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IschemiaCold IschemiaWarm IschemiaMyocardial IschemiaBrain IschemiaReperfusion InjuryTime FactorsOrgan PreservationAmputationDelayed Graft FunctionIschemic Attack, TransientLower ExtremityTissue DonorsGraft SurvivalNephrectomyKidney TransplantationLiver TransplantationCerebrovascular CirculationConstriction, PathologicPeripheral Vascular DiseasesTissue and Organ HarvestingLegDeathDisease Models, AnimalTissue and Organ ProcurementCoronary CirculationCadaverLiving DonorsMyocardiumSaphenous VeinMyocardial Reperfusion InjuryVascular Surgical ProceduresTreatment OutcomeOrgan Preservation SolutionsBiliary TractHeartRaffinoseReperfusionCoronary DiseaseDogsPancreas TransplantationLaparoscopyTransplantsBrain DeathRats, Sprague-DawleyRetrospective StudiesSeverity of Illness IndexRoboticsIschemic PreconditioningGerbillinaeSpinal Cord IschemiaGraft RejectionAllopurinolRats, WistarIschemic Preconditioning, MyocardialPostoperative ComplicationsKidneyPrimary Graft DysfunctionKidney Tubular Necrosis, AcuteNeuroprotective AgentsBile DuctsInfarction, Middle Cerebral ArteryBiliary Tract DiseasesMyocardial ReperfusionLiver FailureHepatic ArteryTissue PreservationDonor SelectionBrainTissue FixationRisk FactorsHindlimbTransplantation, HomologousCerebral InfarctionMyocardial InfarctionFollow-Up StudiesCreatinineRenal ArteryPerfusionAnastomosis, SurgicalLiverHemodynamicsKidney NeoplasmsCardiotonic AgentsConstrictionRisk AssessmentSpecimen HandlingMesenteric Vascular OcclusionProspective StudiesElectrocardiographyReoperationArterial Occlusive DiseasesImmunosuppressive AgentsBrain EdemaMyocardial ContractionNeuronsSurvival RatePatient SelectionExercise TestRegional Blood Flow
NecrosisAcuteSymptomCardiacInfarctionBrain ischemiaSymptomsLate-onsetPerfusionAnterior spinalReperfusion injuryFocalCerebral tissueTissueVasospasmCardiovascularAtrial fibrillationSystemicSubarachnoidPatientsInhibitionStroke onsetIrreversibleBlindnessInjuryImpairmentTransientMetabolicDeficitsOcclusionIschemic strokeVascularBloodHepaticVulnerablePrognosisSeveritySignificantlyHeadacheProthrombin TimeHoursDurationPatient had severeClinicallyEvidence
Necrosis4
  • Acute cerebral infarction leads to cerebral tissue ischemia, hypoxia and necrosis, mainly manifested as a series of neurological deficits such as disturbance of consciousness, aphasia and hemiplegia. (journalmc.org)
  • Fulminant hepatic failure (FHF) is an acute and eventually fatal illness, caused by a severe hepatocyte damage with massive necrosis. (uandes.cl)
  • Our Mesenteric Ischemia/Necrosis solicitors deal with claims using a no win no fee arrangement which means that if you don�t win then you don�t pay them their professional costs. (medneg.com.au)
  • If you would like legal advice at no cost with no further obligation just complete the contact form or email our lawyers offices or use the helpline and a Mesenteric Ischemia/Necrosis solicitor will review your medical negligence compensation claim and phone you immediately. (medneg.com.au)
Acute16
  • The patient had severe cardiac dysfunction and atrial fibrillation and presented with acute ischemia in the right lower limb 24 h after receiving an inferior vena cava filter. (medscape.com)
  • 30%) with acute symptoms of right lower-extremity ischemia. (medscape.com)
  • The onset of action of immediate-release oral isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode. (nih.gov)
  • Acute spinal cord ischemia syndrome is a rare condition comprising a small fraction of neurovascular accidents, the majority of which occur within the cerebral circulation. (biomedcentral.com)
  • In this case report, we review acute spinal cord ischemia syndrome and consider the pathophysiology, diagnostic measures and prognostic factors associated with patient recovery. (biomedcentral.com)
  • Acute spinal cord ischemia syndrome with atypical patterns of sensory deficit is uncommon. (biomedcentral.com)
  • Acute spinal cord ischemia syndrome (ASCIS) is predictably due primarily to pathology in the anterior spinal artery, its feeders or its branches. (biomedcentral.com)
  • The hallmarks of acute spinal cord infarction are a sudden, apoplectic onset of severe back or neck pain (50-80% of cases) accompanied by paraparesis or paraplegia [ 4 ]. (biomedcentral.com)
  • Acute coronary syndrome (ACS) describes any condition characterized by myocardial ischaemia and reduction in blood flow. (hindawi.com)
  • Acute coronary syndrome (ACS) is a cardiovascular disease, which describes any condition characterized by signs and symptoms of sudden myocardial ischaemia and reduction in blood flow to the heart [ 1 ]. (hindawi.com)
  • Patients who develop severe stroke symptoms due to acute internal carotid artery occlusion eventually in combination with a thromboembolic obstruction of the middle cerebral artery incur a major risk of developing extensive MCA infarction with a poor outcome. (ajnr.org)
  • 1 However, there is a subgroup of patients who develop severe stroke symptoms due to acute internal carotid artery occlusion eventually in combination with a thromboembolic obstruction of the central arteries, such as the terminal carotid segment or the middle cerebral artery, and subsequently incur a major risk of developing extensive MCA infarction with a poor outcome. (ajnr.org)
  • 3,162) Metabolic efficiency with ranolazine for less ischemia in Non-ST elevation acute coronary syndromes compared long-term treatment with extended-release ranolazine with placebo, on top of standard therapy, for acute and long-term treatment of patients with non-ST-elevation ACS. (escardio.org)
  • FHF is currently defined as hyperacute (encephalopathy appearing within 7 days of the onset of jaundice), acute (encephalopathy appearing between 8 and 28 days) or subacute (encephalopathy appearing between 5 and 12 weeks). (uandes.cl)
  • Spinal ischemia underlies 6% of acute myelopathies [1]. (fortunejournals.com)
  • The acute syndrome presents with rapidly progressive severe upper abdominal pain , yellow discoloration of the skin and whites of the eyes , liver enlargement , enlargement of the spleen , fluid accumulation within the peritoneal cavity , elevated liver enzymes , and eventually encephalopathy . (wikipedia.org)
Symptom9
  • [ 15 ] expanding the treatment window from 3 hours to 4.5 hours after symptom onset. (medscape.com)
  • The patient was hospitalized 6 days after symptom onset. (cdc.gov)
  • On day 8 after symptom onset, he had pulseless electrical heart activity probably caused by metabolic acidosis. (cdc.gov)
  • He died on day 11 after symptom onset. (cdc.gov)
  • The trial included 11 016 patients with a noncardioembolic, nonsevere ischemic stroke or high-risk TIA, including 10 803 with modified Rankin Scale score (mRS) recorded at 30 days.Interventions: Ticagrelor (180-mg loading dose on day 1 followed by 90 mg twice daily for days 2-30) or placebo within 24 hours of symptom onset. (kb.se)
  • The medical records of 5 patients presenting with signs and symptom of delayed-onset PUK following ocular alkali injury were reviewed. (entokey.com)
  • While the causes of myelopathy may be multiple, the acuity of presentation and symptom onset frame a practical approach to the differential diagnosis. (bvsalud.org)
  • of symptoms, and common compli- the symptom interpretation and care- Fourteen patients were excluded be- cations include recurrent ischaemia, seeking behaviour. (who.int)
  • Alzheimer's is characterized by pathologic changes that precede symptom onset by decades, yet the disease is diagnosed by clinical symptoms. (medscape.com)
Cardiac5
  • Whereas coma and seizures are well-recognized neurological sequelae of hypoglycaemia, much interest is currently focused on the potential for hypoglycaemia to cause dangerous and life-threatening cardiac complications, such as arrhythmias and myocardial ischaemia, and whether recurrent severe hypoglycaemia can cause permanent cognitive impairment or promote cognitive decline and accelerate the onset of dementia in middle-aged and elderly people with diabetes mellitus. (nature.com)
  • Ischemia and reperfusion can cause serious brain damage in stroke or cardiac arrest. (benbest.com)
  • Reductions in heart rate, blood pressure, peripheral vascular resistance, cardiac output, and central venous pressure occur during severe hypothermia. (wildliferesearch.com)
  • Absence of coronary artery disease: Cardiac ischaemia with angina pectoris can exist in the absence of significant coronary artery disease, possibly due to microcoronary dysfunction (up to 10% of patients of which a majority of women). (escardio.org)
  • It is estimated that 20-25 percent of cardiac output goes to the GI tract at any given period of time. (medneg.com.au)
Infarction6
  • When a cerebral infarction occurs, especially in the brain stem where the nerve fiber bundles in the respiratory and circulatory centers are concentrated, if the treatment is not treated in time, the mortality rate is as high as 80-90%, which seriously threatens the life of the patient [ 4 , 5 ]. (journalmc.org)
  • Although cardiovascular death, myocardial infarction or severe recurrent ischaemia were not proven better with ronalazine, the individual component of recurrent ischaemia was significantly reduced by ranolazine - demonstrated as safe. (escardio.org)
  • More cardiovascular events, including myocardial ischemia and/or infarction, were observed in treatment-experienced subjects who received maraviroc. (drugs.com)
  • Ischemia results from mass effect and disruption of blood flow, which may cause infarction of the spinal cord. (medscape.com)
  • Transient Ischemic Attack (TIA) A transient ischemic attack (TIA) is focal brain ischemia that causes sudden, transient neurologic deficits and is not accompanied by permanent brain infarction (eg, negative results on diffusion-weighted. (msdmanuals.com)
  • Ischemic Stroke Ischemic stroke is sudden neurologic deficits that result from focal cerebral ischemia associated with permanent brain infarction (eg, positive results on diffusion-weighted MRI). (msdmanuals.com)
Brain ischemia18
Symptoms10
  • Ischemia within the arteries branching from the internal carotid artery may result in symptoms such as blindness in one eye, weakness in one arm or leg, or weakness in one entire side of the body. (wikipedia.org)
  • Ischemia within the arteries branching from the vertebral arteries in the back of the brain may result in symptoms such as dizziness, vertigo, double vision, or weakness on both sides of the body[citation needed]. (wikipedia.org)
  • Further, symptoms can last from a few seconds to a few minutes or extended periods of time. (wikipedia.org)
  • Nabeel Khan, MD, Associate Professor of Clinical Medicine, University of Pennsylvania, who led the study said, "since IBD symptoms can be severe, maintaining a stable condition is important for IBD management. (biospace.com)
  • Some reported symptoms of using nasal decongestants include nausea, vomiting, seizures, sudden onset of severe headache, confusion and visual disturbances. (healthwire.co)
  • Immediately discontinue maraviroc and other suspected agents if signs or symptoms of severe skin or hypersensitivity reactions develop and monitor clinical status, including liver aminotransferases, closely. (drugs.com)
  • This can happen within twelve hours after the onset of symptoms. (medneg.com.au)
  • Signs and symptoms of mesenteric ischaemia include severe abdominal pain with a lack of obvious physical findings. (medneg.com.au)
  • There is a significant reduction in renal mass (50%-60%) and reduced GFR before the onset of any significant symptoms or any minor signs and symptoms are indicated. (petnvet.in)
  • Symptoms include sudden, severe headache, usually with loss or impairment of consciousness. (msdmanuals.com)
Late-onset3
  • citation needed] Late onset depression is increasingly seen as a distinct sub-type of depression, and can be detected with an MRI. (wikipedia.org)
  • This is a descriptive case series of patients with late-onset PUK following alkali ocular injury. (entokey.com)
  • Yet, we couldn´t find any reported case of a trauma patient, that describes a late onset complete paraplegia of the lower limbs caused by spinal chord ischaemia without a spinal (chord) injury. (fortunejournals.com)
Perfusion1
Anterior spinal2
  • Mid-thoracic levels are most vulnerable to ischemia (for example, as a result of thrombosis) as there is only one radicular artery supplying the anterior spinal artery in this region, and sparse anastomoses. (biomedcentral.com)
  • The classic presentation for anterior spinal artery ischemia or infarct is sensory deficits in the following pattern: distal to the lesion, pain and temperature are lost bilaterally (owing to the involvement of anterolateral spinothalamic tracts), but light touch, vibration and position sense are preserved (owing to sparing of dorsal columns). (biomedcentral.com)
Reperfusion injury1
Focal1
  • In experimental focal cerebral ischemia, Rock and roll inhibition continues to be uniformly efficacious.1, 2, 3, 4 Generally, previous treatment onset affords higher effectiveness in focal cerebral ischemia. (bio-biz-navi.com)
Cerebral tissue1
Tissue6
  • and global ischemia, which encompasses wide areas of brain tissue. (wikipedia.org)
  • Clotting time of PLASMA recalcified in the presence of excess TISSUE THROMBOPLASTIN. (lookformedical.com)
  • Ischemia is a restriction of blood and the oxygen it carries that creates tissue or organ damage. (millerandzois.com)
  • Prior research has shown that use of any antipsychotic is associated with smaller brain tissue volumes, including white matter reduction and that this brain shrinkage is dose dependent and time dependent. (worldsbest.rehab)
  • Naturally when endothelial injury occurs, after some time clot is formed, and endothelial tissue releases tissue plasminogen activator. (howmed.net)
  • Treatment of mesenteric ischemia include having a surgical embolectomy, resection of dead tissue and revascularization of the mesenteric arteries. (medneg.com.au)
Vasospasm3
  • In a study that compared three-dimensional (3D) spin-echo-based black-blood MRA (BBMRA) with time-of-flight (TOF)-MRA for detection of cerebral vasospasm in the early posttreament period after subarachnoid hemorrhage, Takano et al found that BBMRA, owing to its contrast properties, may be superior to TOF-MRA for the evaluation of intracranial arteries. (medscape.com)
  • For this reason, routine surveillance imaging studies are carried out to supplement the neurologic examination with the aim of diagnosing vasospasm before the onset of delayed cerebral ischemia (DCI). (medscape.com)
  • 4 Fluorescein angiographic findings support the hypothesis that retinal detachment in preeclampsia/eclampsia is secondary to choroidal ischemia from intense arteriolar vasospasm. (aao.org)
Cardiovascular1
  • Secondary objectives include: time to first investigator evaluation of AHRE episodes, regardless of its duration, time to anticoagulant therapy onset, time to any medical reaction related to the treatment of new onset atrial arrhythmia, time to cerebral ischemia, and time to first hospitalization due to cardiovascular issues [ Table 1 ]. (jafib.com)
Atrial fibrillation2
  • Atrial fibrillation and ventricular tachycardia also may occur in cases of severe hypothermia. (wildliferesearch.com)
  • The RAPID study is a multicenter, prospective, non-interventional study designed to compare the time from onset to first physician's evaluation of AHRE episode with arrhythmic burden ≥5% (72 minutes) for pacemaker recipients without atrial fibrillation history, between patients followed with RM or conventionally with annual in-hospital visits. (jafib.com)
Systemic5
  • Hepatotoxicity has been reported which may be preceded by severe rash or other features of a systemic allergic reaction (e.g., fever, eosinophilia, or elevated IgE). (drugs.com)
  • Hepatotoxicity accompanied by severe rash or systemic allergic reaction, including potentially life-threatening events, has been reported. (drugs.com)
  • Empiric anti-fungal therapy should be considered in patients at risk for invasive fungal infections who develop severe systemic illness. (rxlist.com)
  • Ischaemia to the intestinal lining results in a release of toxins, bacteria and vasoactive mediators so that there is a systemic response to the iscahaemia. (medneg.com.au)
  • Possible mechanisms for these changes include hormonal changes, endothelial damage, hypoperfusion ischemia/edema, and coexisting systemic vascular disease. (aao.org)
Subarachnoid1
  • Definition of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage as an outcome event in clinical trials and observational studies: proposal of a multidisciplinary research group. (medscape.com)
Patients19
  • Current knowledge of the long-term outcome in patients with spinal cord ischemia is based on only a few small studies, some of which are discussed here. (biomedcentral.com)
  • Nearly all patients with type 1 diabetes (younger-onset patients) and more than 60% of patients with type 2 diabetes (older-onset patients) develop retinopathy during the first two decades of disease, and approximately 4% and 2% of these patients respectively, become legally blind (defined as visual acuity of 1/20). (institut-vision.org)
  • Retinopathy is already present at the time of diagnosis in 20% of patients with type 2 diabetes. (institut-vision.org)
  • Among patients with younger-onset diabetes, the prevalence is estimated at approximately 8% at 3 years, 25% at 5 years, 60% at 10 years, and 80% at 15 years. (institut-vision.org)
  • All patients received aspirin, 300 to 325 mg on day 1 followed by 75 to 100 mg daily for days 2 to 30.Main Outcomes and Measures: Time to the occurrence of disabling stroke (progression of index event or new stroke) or death within 30 days, as measured by mRS at day 30. (kb.se)
  • The primary end point was time to the occurrence of stroke or death within 30 days.Results:Of 11 016 randomized patients, 2351 (21.3%) patients had an ipsilateral atherosclerotic stenosis. (kb.se)
  • Patients treated with ranolazine had significantly better exercise duration - an ncrease by 115 seconds from baseline versus 91 seconds in placebo group - time to onset of angina, and fewer angina attacks. (escardio.org)
  • Spinal ischemia in traumatized patients is rarely described, and when it occurs, it is usually associated with direct trauma to the spine and consecutive vascular injury. (fortunejournals.com)
  • To date, no case has been described in the literature in which traumatized patients developed vascular myelopathy with a time delay without the presence of direct spinal trauma or direct vertebral vascular injury. (fortunejournals.com)
  • Patients should all the time be questioned concerning adherence to and tolerance of prescribed remedy. (atpobtvs.com)
  • Maraviroc tablets are contraindicated in patients with severe renal impairment or end-stage renal disease (ESRD) (CrCl less than 30 mL per minute) who are concomitantly taking potent CYP3A inhibitors or inducers. (drugs.com)
  • Severe and potentially life-threatening skin and hypersensitivity reactions have been reported in patients taking maraviroc. (drugs.com)
  • If patients with severe renal impairment or ESRD receiving maraviroc (without concomitant CYP3A inducers or inhibitors) experience postural hypotension, the dose of maraviroc should be reduced from 300 mg twice daily to 150 mg twice daily. (drugs.com)
  • The objective of this study is to evaluate the time from onset to first physician's evaluation of AHRE with arrhythmic burden ≥5% (72 minutes) in ordinary clinical practice for pacemaker patients without documented AF history and compare it between patients followed with RM or conventionally with annual in-hospital visits. (jafib.com)
  • The majority of patients have a slower-onset form of Budd-Chiari syndrome. (wikipedia.org)
  • Exudative (or serous) retinal detachment occurs in less than 1 percent of patients with preeclampsia and in 10 percent with eclampsia, although preeclamptic and eclamptic women with HELLP syndrome ( hemolysis/elevated liver enzymes/low platelet count) may be approximately seven times more likely to develop a retinal detachment than those who do not have the syndrome 4 (Figs. 1, 2). (aao.org)
  • We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subcortical infarcts according to the ASCO classification with baseline and follow-up MRI (≥90 days of stroke onset). (frontiersin.org)
  • In the absence of pharmacokinetic studies in patients with stable severe hepatic impairment (Child Pugh grade C) without decompensation, caution should be exercised when ritonavir is used as a pharmacokinetic enhancer as increased levels of the co-administered protease inhibitor may occur. (who.int)
  • In a multivariate logistic regression analysis, the type of AMI was classified based on electrocardiography findings (odds ratio 5.18, 95% confidence interval: 1.69-15.91, P=0.004) and was independently associated with a long prehospital delay time, indicating that patients with S T segment elevation MI would seek early medical care. (who.int)
Inhibition2
  • Rock and roll inhibition offers antithrombotic and vasodilator results that may be helpful in severe ischemic heart stroke.1, 4, 7, 8 However, exactly the same results could be harmful in main intracerebral hemorrhage (ICH). (bio-biz-navi.com)
  • Although some adults infected with influenza 2009 A(H1N1)pdm09 viruses mounted high hemagglutination inhibition (HAI) antibody response, they still suffered from severe disease, or even death. (cdc.gov)
Stroke onset1
  • MRI scans were performed within seven days of stroke onset, and then neuroimaging markers of SVD including WMH, lacunes, cerebral microbleeds (CMB), and perivascular spaces (PVS) , SVD burden scores were assessed. (researchsquare.com)
Irreversible1
  • Severe neurologic deficits may develop and become irreversible within minutes or a few hours. (msdmanuals.com)
Blindness2
  • In the younger-onset group, approximately 90% of blindness is attributable to DR. In the older-onset group, in which other eye diseases may be present, one-third of the cases of legal blindness are due to DR. (institut-vision.org)
  • The degree of vision impairment can range from severe visual impairment to total blindness. (lindastcviteachershare.com)
Injury4
  • To report delayed-onset peripheral ulcerative keratitis (PUK) following alkali injury. (entokey.com)
  • Our attorneys explain how these HIE malpractice lawsuits work, which of these ischemia cases are most viable, and the typical settlement amounts and jury compensation awards our birth injury attorneys see in these cases. (millerandzois.com)
  • ischemia": not enough blood supply to the brain), developmental brain defects, head injury, hydrocephalus, and infections of the central nervous system, such as meningitis, and encephalitis. (lindastcviteachershare.com)
  • Ingestion of concentrated hydrochloric acid can cause severe corrosive injury to the lips, mouth, throat, esophagus, and stomach. (cdc.gov)
Impairment1
  • The degree of neurological damage and visual impairment depends upon the time of onset, as well as the location and intensity of the insult. (lindastcviteachershare.com)
Transient1
  • Recounting the days of Laney's first transient ischemic attacks (TIAs) and strokes and the horror and confusion that accompanied that time is something I would never wish on any parent. (aap.org)
Metabolic3
  • Ischemia leads to alterations in brain metabolism, reduction in metabolic rates, and energy crisis. (wikipedia.org)
  • In times of high metabolic demand and adequate availability of oxygen, elevated calcium in mitochondria can increase ATP production by stimulation of three enzymes in the Krebs citric acid cycle: pyruvate dehydrogenase, alpha-ketoglutarate and isocitrate dehydrogenase. (benbest.com)
  • Severe shivering contributes to lactic acid accumulation and resultant metabolic abnormalities. (wildliferesearch.com)
Deficits1
  • Although pre\medical center administration significantly shortens enough time to treatment,5 medical exam alone is usually not adequate to accurately determine the etiology of severe neurological deficits in the field.6 For instance, the necessity to distinguish ischemic from hemorrhagic heart stroke by neuroimaging is arguably the largest contributor to hold off of thrombolysis. (bio-biz-navi.com)
Occlusion1
  • Pretreatment anteroposterior (AP) pelvic image shows severe atherosclerotic disease with attenuated flow through the left superficial femoral artery (SFA), which suggests a distal occlusion. (medscape.com)
Ischemic stroke2
  • Rho\connected kinase (Rock and roll) can be an growing target in severe ischemic stroke. (bio-biz-navi.com)
  • A study reports high levels of CRP associated with clinical prognosis in the time window between 12 and 72 hours after ischemic stroke [ 17 , 18 ]. (hindawi.com)
Vascular1
  • More common causes are aneurysms of the aorta or ischemia after aortic surgery, compression of vascular structures by tumors, thrombosis or embolism and arterio-venous malformations. (fortunejournals.com)
Blood5
  • Ischemia is the condition suffered by tissues & organs when deprived of blood flow -- mostly the effects of inadequate nutrient & oxygen. (benbest.com)
  • In both cases, there is a risk of reduced blood supply to the brain, known as ischaemia . (healthwire.co)
  • Creatine phosphokinase (CPK) increases in the blood during severe hypothermia as a result of cellular damage. (wildliferesearch.com)
  • Mesenteric ischaemia is a blockage or interruption in the blood flow of the intestine. (medneg.com.au)
  • This isa sudden loss of kidney functions due to a blunt trauma, severe haemorrhage, loss of body fluid in severe diarrhoea causing fluid-electrolytes imbalance and blood volume. (petnvet.in)
Hepatic1
  • Hepatic laboratory parameters including ALT, AST, and bilirubin should be obtained prior to starting maraviroc tablets and at other time points during treatment as clinically indicated. (drugs.com)
Vulnerable1
  • The splenic flexure is partially supplied by both the SMA and the IMA and is vulnerable to ischemia. (medneg.com.au)
Prognosis1
  • The prognosis of spinal ischemia depends on the severity of the neurologic deficit that presents at the beginning [5]. (fortunejournals.com)
Severity1
  • Initial stroke severity, degree of successful revascularization, and the side of ischemia were found to independently predict the functional outcome at 3 months after treatment. (ajnr.org)
Significantly1
  • The level of consciousness was significantly reduced at the onset, the tone of the speech was not clear, the limb muscle strength was significantly reduced, there was confusion in the course of the disease and magnetic resonance imaging (MRI) showed that the midline shift was obvious. (journalmc.org)
Headache2
  • Headache is usually severe, peaking within seconds. (msdmanuals.com)
  • A 39-year-old woman experiences vomiting and a severe occipital headache that she describes as the worst she has ever had. (medscape.com)
Prothrombin Time2
  • Factors that are valuable in assessing the likelihood of spontaneous recovery are age, etiology, degree of encephalopathy, prothrombin time and serum bilirubin. (uandes.cl)
  • Prothrombin time. (lookformedical.com)
Hours4
  • What began as a possible fiasco ended, in those brief hours of demonstration time, in every little thing Cajal had hoped for: the chance to current the evidence to the main authorities-he mentions His, Schwalbe, Retzius, Waldeyer, van Gehuchten, 'and particularly K�lliker' (Cajal, 1989)-and acquire their acceptance of his outcomes. (dnahelix.com)
  • Best results are obtained within 6 hours of attack, although administered up to 24 hours, the benefits decrease as time from onset of attack is increased. (howmed.net)
  • Prehospital delay time ranged from 15 minutes to 10 days, with a median of 2 hours (interquartile range: 9.50). (who.int)
  • One hundred and twenty-six pa- within the first 2 hours after the onset tional variables (14,15,21) influenced tients were approached in the 2 months. (who.int)
Duration1
  • is defined as the gradual loss of renal structure or functions which may have happened slowly and over a long period of time with a minimum of three months duration. (petnvet.in)
Patient had severe1
  • The patient had severe loss of nerve function at the onset of the disease. (journalmc.org)
Clinically1
  • 4. Known clinically significant gastric emptying abnormality (e.g., severe diabetic gastroparesis or gastric outlet obstruction). (who.int)
Evidence1
  • As this country considers its medical future, it is time for coordinated care, and evidence supports the effective- to integrate mental health care with general medical care. (cdc.gov)