Severe aortic stenosis in patients. Medical search. Frequent questions

Transcatheter aortic valve implantation is currently being evaluated in patients with severe aortic stenosis who are considered high-risk surgical candidates. (nih.gov)
This study aimed to detect incidences, causes, and correlates of mortality in patients ineligible to participate in transcatheter aortic valve implantation studies. (nih.gov)
From April 2007 to July 2009, a cohort of 362 patients with severe aortic stenosis were screened and did not meet the inclusion/exclusion criteria necessary to participate in a transcatheter aortic valve implantation trial. (nih.gov)
Patients with severe symptomatic aortic stenosis not included in transcatheter aortic valve implantation trials do poorly and have extremely high mortality rates, especially in nonsurgical groups, and loss of quality of life in surgical groups. (nih.gov)
Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement: How Would You Manage This Patient With Severe Aortic Stenosis? (acpjournals.org)
Surgical aortic valve replacement (SAVR) was the standard of care until transcatheter aortic valve replacement (TAVR) was shown to have lower mortality rates in patients at the highest surgical risk and was recommended for this group in the 2014 American Heart Association/American College of Cardiology (AHA/ACC) guidelines. (acpjournals.org)
5. Arora S , Misenheimer JA , Ramaraj R . Transcatheter aortic valve replacement: comprehensive review and present status. (acpjournals.org)
The final cohort comprised of 18 subjects (86 ± 4 years, 28% males) with severe aortic stenosis who underwent a Transcatheter Aortic Valve Implantation (TAVI). (atlantis-press.com)
Among patients with severe isolated aortic stenosis younger than 65, the rate of transcatheter aortic valve replacement (TAVR) now almost matches that of surgical aortic valve replacement (SAVR) despite guideline recommendations to the contrary, a study in a national US population shows. (medscape.com)
TAVI = Transcatheter Aortic Valve Implantation. (medtronic.com)
Transcatheter aortic valve replacement (TAVR), initially developed as a less invasive treatment for inoperable patients, has successfully been used in healthier patient cohorts. (wustl.edu)
The Valve Academic Research Consortium (VARC) has proposed a standardized definition of bleeding in patients undergoing transcatheter aortic valve interventions (TAVI). (123dok.net)
Aims The present study aimed to evaluate the impact of prior cardiovascular events (CVE) on outcome in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR). (tau.ac.il)
Predictors of Mortality and Symptomatic Outcome of Patients With Low-Flow Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. (omicsdi.org)
Impaired left ventricular (LV) ejection fraction is a common finding in patients with aortic stenosis and serves as a predictor of morbidity and mortality after transcatheter aortic valve replacement. (omicsdi.org)
We wanted to examine the impact of LV ejection fraction, mean pressure gradient, and stroke volume index on the outcome of patients treated by transcatheter aortic valve replacement. (omicsdi.org)
Despite increased long-term mortality, high procedural success and excellent functional improvement support transcatheter aortic valve replacement in patients with LF severe aortic stenosis. (omicsdi.org)
D. He should not be considered a candidate for either surgical or transcatheter aortic valve replacement (AVR) and offered medical management only. (acc.org)
Transcatheter Aortic Valve Replacement (TAVR) or implantation (TAVI) is a minimally invasive heart procedure to repair the aortic valve by wedging it with a replacement valve. (yashodahospitals.com)
Transcatheter Aortic Valve Replacement (TAVR) is used for patients with aortic stenosis, who are very weak and cannot tolerate a major heart surgery. (yashodahospitals.com)
Transcatheter Aortic Valve Replacement (TAVR) is a catheter-based interventional method of repairing the stenosed aortici valve. (yashodahospitals.com)
Catheter is a long narrow tube that is used to implant a transcatheter aortic valve over a damaged valve. (yashodahospitals.com)
Transcatheter aortic valve is a specialized prosthetic valve that is different from the ones used in open surgery. (yashodahospitals.com)
Then, he makes a small incision in the groin, leg or chest to insert and guide the transcatheter aortic valve (TAV) in the heart and implants it over the existing valve. (yashodahospitals.com)
1,2 Valve replacement, either surgical or catheter directed (ie, transcatheter aortic valve replacement, or TAVR), is the mainstay of treatment for advanced disease. (emra.org)
Patients with severe aortic stenosis may now be candidates for transcatheter aortic valve replacement, or TAVR. (samhealth.org)
MDT ) announced today that it received CE Mark approval for its Evolut transcatheter aortic valve implantation (TAVI) system. (massdevice.com)
CHICAGO, IL-Transcatheter aortic valve replacement using a second-generation balloon-expandable device is at least as good as surgery in intermediate-risk patients with severe symptomatic aortic stenosis. (tctmd.com)
PARTNER 2A randomized 2,032 intermediate-risk patients with severe symptomatic aortic stenosis at one of 57 centers to either open surgical valve replacement or transcatheter aortic valve implantation with the Sapien XT. (tctmd.com)
Transcatheter aortic valve implantation (TAVI) is a well-recognized and established therapy for severe aortic stenosis, with expanding indications toward younger patients with low surgical risk profile. (frontiersin.org)
Transcatheter aortic valve implantation (TAVI) has been widely recognized as a safe and effective treatment for aortic stenosis (AS) in patients who cannot undergo surgical aortic valve replacement (SAVR) or are at high or intermediate surgical risk ( 1 - 4 ). (frontiersin.org)
AIMS : Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. (lu.se)
To assess the safety and effectiveness of performing percutaneous coronary intervention (PCI) before transcatheter aortic valve implantation (TAVI). (bvsalud.org)
Intentional laceration of the aortic leaflet during transcatheter aortic valve replacement (TAVR) may prevent the rare but fatal complication of coronary artery obstruction, a first-in-humans study suggests. (medscape.com)
In elderly (75 years or older) patients living in Latin America with severe symptomatic aortic stenosis candidates for transfemoral approach, the panel suggests the use of transcatheter aortic valve implant (TAVI) over surgical aortic valve replacement (SAVR). (bvsalud.org)

Atrial lead insertion during cardiac implantable electronic devices implantation in patients with atrial arrhythmia on hospital admission, when does the struggle for sinus rhythm make sense? (escardio.org)

We performed cardiac catheterization in 486 patients (age 74 ± 10 years, 58% males) with severe AS [indexed aortic valve area 0.41 ± 0.13 cm, left ventricular ejection fraction 58 ± 12%]: 50 patients had AF, and 436 patients had SR. All patients underwent surgical (n = 350) or transcatheter (n = 136) AVR. (kssg.ch)

In the 2017 AHA/ACC focused update, evidence of benefit and noninferiority extended the use of TAVR to intermediate-risk patients. (acpjournals.org)
More recent studies suggest potential benefit to low-risk patients, although no published guidelines yet recommend the use of TAVR for this population. (acpjournals.org)
Although TAVR has less than 10-year experience with valve durability, it has lower or noninferior primary end points, such as mortality and stroke, and fewer periprocedural complications among anatomically permissive patients. (acpjournals.org)
Here, a cardiologist and a cardiothoracic surgeon debate the risks and benefits of TAVR versus SAVR for a patient with severe symptomatic AS who is at low risk for surgical death. (acpjournals.org)
The 2020 American Heart Association/American College of Cardiology (AHA/ACC) valve guideline recommends SAVR for patients younger than 65 with severe aortic stenosis, the researchers note, but their study showed "near equal utilization between TAVR and SAVR in these younger patients by 2021," at 48% and 52% respectively. (medscape.com)
To our knowledge, the current findings represent the first national temporal trends study stratifying [aortic stenosis] therapies according to guideline-recommended age groups: our observations demonstrate the dramatic growth of TAVR in all age groups, including young patients," the researchers conclude. (medscape.com)
These findings have implications for lifetime management of younger patients who undergo TAVR, they write, "including issues related to lifetime coronary access, valve durability and the potential for subsequent TAVR procedures over time. (medscape.com)
From the Vizient clinical database, including more than 250 US academic centers that perform both TAVR and SAVR, the researchers identified 142,953 patients who underwent TAVR or SAVR for isolated aortic stenosis from October 1, 2015, to December 31, 2021. (medscape.com)
The one that's surprising, and in contradiction to the guideline, is the growth of TAVR in young patients less than 65. (medscape.com)
Among patients younger than 65, prior bypass surgery and congestive heart failure predicted the use of TAVR instead of surgery, whereas bicuspid aortic valve disease was the biggest predictor of surgery instead of TAVR. (medscape.com)
Most studies on TAVR valve durability are limited to patients in the randomized trials who were primarily in their mid-70s to mid-80s, some of whom died before a 10-year follow-up, Dauerman noted. (medscape.com)
European guidelines recommend surgery for patients younger than 70, and it would be interesting to see if clinicians there follow this recommendation or if TAVR is now the preferred approach, he added. (medscape.com)
There is a need for further, longer study of TAVR in younger patients, he said, to determine whether there are long-term clinical issues of concern. (medscape.com)
Age is only one of multiple patient characteristics that enter into consideration of TAVR vs SAVR," said Carroll, from Anschutz Medical Campus, University of Colorado, Aurora. (medscape.com)
Carroll was lead author of a review article published in 2020 based on data from the ACC-Society of Thoracic Surgeons (STS)-Transcatheter Valve Therapy (TVT) registry on 276,316 patients who had TAVR in the United States from 2011-2019. (medscape.com)
In 2017, TAVR became the most common approach for aortic valve replacement in the United States. (wustl.edu)
Observations: During the past decade, the Placement of Aortic Transcatheter Valve (PARTNER) trials (for balloon-expandable valves) and the CoreValve trials (for self-expandable valves) investigated the performance of TAVR in progressively lower-risk patient cohorts. (wustl.edu)
The initial trials demonstrated TAVR to be superior (PARTNER B) and noninferior (CoreValve Extreme Risk) to optimal medical therapy in inoperable patients. (wustl.edu)
However, owing to the fundamentally different nature of the procedure, some complications have been more prevalent with TAVR, most notably moderate or severe paravalvular leak, conduction abnormalities necessitating permanent pacemaker placement, and vascular complications. (wustl.edu)
Conclusions and Relevance: The results of the groundbreaking TAVR trials from the past decade have led to a revolution in the treatment of aortic stenosis. (wustl.edu)
There are now 3 US Food and Drug Administration-approved TAVR devices, and with the encouraging results from the latest low-risk trials, TAVR is likely going to become the dominant treatment for symptomatic severe aortic stenosis. (wustl.edu)
Methods and results Patients with severe AS undergoing TAVR between May 2007 and March 2015 were included and categorized to patients with and without prior stroke, defined as embolic, hemorrhagic stroke and transit ischemic attack. (tau.ac.il)
A cohort of 662 consecutive patients with severe AS undergoing TAVR were included in the analysis. (tau.ac.il)
Transfemoral access was used in 78% (571), and pre-TAVR balloon aortic valvuloplasty was performed in 87% (574). (tau.ac.il)
Therefore, history of prior stroke should not be considered an exclusion criterion for TAVR in patients with severe AS. (tau.ac.il)
Use our search tool to find a physician near you who is experienced in treating severe aortic stenosis with TAVR. (medtronic.com)
Hear stories from TAVR patients like Darian. (medtronic.com)
We would typically wait for patients to develop angina or exertional breathlessness, presyncope, or syncope before offering them an intervention, be it surgical aortic valve replacement or TAVR," said Cahill. (tctmd.com)
TAVR is a novel procedure which is well tolerated by many patients for whom an open heart surgery is considered to be risky. (yashodahospitals.com)
TAVR is indicated for a patient with intermediate or high-risk for complications related to surgical aortic valve replacement. (yashodahospitals.com)
The TAVR procedure is a minimally invasive alternative and is considered safer for many older patients for whom a major surgery could be prohibitively risky. (samhealth.org)
A TAVR procedure is done using a long, thin, hollow tube, called a catheter, which is usually inserted through a blood vessel in the groin," said Cardiac Surgeon Edward Bender, MD . "Using high-tech imaging equipment, we guide the catheter, which carries a replacement valve to your heart's damaged aortic valve, where the replacement valve is expanded. (samhealth.org)
In a TAVR procedure, the patient can be under less anesthetic and the recovery time is much faster - patients are usually up and about the next day, and on their way home within three days. (samhealth.org)
A patient who has had the TAVR procedure often starts feeling better immediately, because they now have a working aortic valve," said Dr. Bender. (samhealth.org)
Not every severe aortic stenosis patient is an appropriate candidate for TAVR. (samhealth.org)
Endocarditis (infection of the heart) would disqualify a patient for TAVR. (samhealth.org)
But for many older patients with severe, symptomatic aortic stenosis, TAVR can be a game changer," said Dr. Toggart. (samhealth.org)
Results from the PARTNER 2, Cohort A trial showed that death or disabling stroke at 2 years-the trial's primary endpoint-were not significantly different for patients randomized to TAVR using the Sapien XT (Edwards Lifesciences) or open-heart surgery. (tctmd.com)
All the same, "in patients who are candidates for transfemoral access, TAVR may result in additional clinical advantages," Smith noted. (tctmd.com)
No difference in the primary endpoint was seen between patients treated surgically and those who underwent a transthoracic TAVR procedure. (tctmd.com)
Questioned about this point during the late-breaking clinical trial session, Smith commented: "My own guess is that, as time goes on, there will be still be some patients who can't have transfemoral TAVR and shouldn't have surgery and still need some other access route to have TAVR. (tctmd.com)
The present study, published in the April 9 issue of JACC Cardiovascular Interventions , involved compassionate use of BASILICA in seven patients considered unsuitable for surgery and turned down for TAVR in CoreValve (Medtronic) and Sapien (Edwards Lifesciences) trials. (medscape.com)

A patient presenting with uncontrolled heart failure should be treated supportively with oxygen, cardiac and oximetry monitoring, intravenous access, loop diuretics, nitrates (keep in mind the potential nitrate sensitivity of patients with aortic stenosis), morphine (as needed and tolerated), and noninvasive or invasive ventilatory support (as indicated). (medscape.com)
We hypothesized that cardiac steatosis is involved in the pathophysiology and also assessed whether it is reversible after aortic valve replacement. (ox.ac.uk)
METHODS AND RESULTS: Thirty-nine patients with severe AS (symptomatic=25, asymptomatic=14) with normal LV ejection fraction and no significant coronary artery disease and 20 age- and sex-matched healthy controls underwent cardiac 1H-magnetic resonance spectroscopy and imaging for the determination of steatosis (myocardial triglyceride content) and cardiac function, including circumferential strain (measured by magnetic resonance tagging). (ox.ac.uk)
Initially, these compensatory changes allow the LV to maintain cardiac output, and patients are asymptomatic. (medscape.com)
As the stenosis progresses, patients are unable to increase stroke volume, and as a result, they are unable to increase cardiac output so as to compensate for increases in myocardial oxygen demand. (medscape.com)
Unexpected events included cardiac death or hospitalization with heart failure in patients who had not been recommended valve replacement. (cpxinternational.com)
In clinical trials, the safety profile of clevidipine was generally similar to sodium nitroprusside, nitroglycerin, or nicardipine in patients undergoing cardiac surgery. (wikipedia.org)
Background and Objectives: We investigated echocardiographic predictors: left ventricular (LV) geometric changes following aortic valve replacement (AVR) according to the late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) in patients with severe aortic stenosis (AS) and preserved LV systolic function. (elsevierpure.com)
Patients with asymptomatic aortic stenosis (AS) followed at specialty heart-valve hospitals are at a low risk of sudden cardiac death and have "good midterm survival" outcomes, suggest the results of a new analysis. (tctmd.com)
To TCTMD, Cahill highlighted the ongoing EVOLVED study, which is testing whether cardiac fibrosis detected on MRI can successfully guide early valve replacement in asymptomatic patients with severe AS. (tctmd.com)
It is a catheter-based procedure which is performed by the interventional cardiologist and cardiac surgeon for patients with calcified, narrowed aortic valve (aortic valve stenosis). (yashodahospitals.com)
Patients with critical AS have a fixed cardiac output and cannot meaningfully increase cardiac output to meet the physiologic demands of critical illness. (emra.org)
Samaritan Heart Center provides a wide range of advanced cardiology and cardiac surgery services, with clinics in Albany, Corvallis, Lebanon, Lincoln City and Newport, and also serves patients from Eugene, Salem and neighboring areas. (samhealth.org)
In patients with depressed cardiac function, both dobutamine and isoproterenol increase the cardiac output to a similar degree. (drugs.com)
In the limited number of patients who were studied for 24, 48, and 72 hours, a persistent increase in cardiac output occurred in some, whereas output returned toward baseline values in others. (drugs.com)
With these approvals, more patients will now be candidates for the Evolut TAVI system while surgical aortic valve replacement will evolve to serve a more complex patient population," Medtronic VP & chief medical officer for the structural heart & cardiac surgery business Dr. Pieter Kappetein said in a news release. (massdevice.com)
She also has a specific interest in the burgeoning field of Cardio-Rheumatology, focused on cardiac diseases among patients with rheumatologic conditions such as rheumatoid arthritis, systemic lupus erythematosus, scleroderma, and ankylosing spondylitis, among others. (stanford.edu)
Her clinical research in this area has focused on the evaluation of structural cardiac disease and diastolic dysfunction in ankylosing spondylitis patients, primarily using echocardiography. (stanford.edu)
Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, affecting 1-2% of the population, and is the cause of a significant proportion of aortic valve disease in young adults ( 9 ). (frontiersin.org)

Key pressure waveform features were extracted and wave separation analysis was performed by combining aortic pressure and flow (Doppler echocardiography) data before and after the valve replacement. (atlantis-press.com)
A low-dose dobutamine stress echocardiography may be used for this purpose in patients with classical LF-LG AS, whereas aortic valve calcium scoring by multi-detector computed tomography is the preferred modality in those with paradoxical LF-LG or NF-LG AS. (omicsdi.org)
All patients were examined with transthoracic echocardiography (TTE), CMR before and after AVR (in the hospital) and serial TTEs (at 6 and 12 months) were repeated. (elsevierpure.com)
In addition to the identification of a systolic ejection murmur, bedside echocardiography can help screen patients. (emra.org)
Echocardiography revealed severe aortic regurgitation without any stenosis. (bmj.com)

Mild aortic regurgitation. (acc.org)
There were peripheral signs of aortic regurgitation. (bmj.com)
With a clinical diagnosis of aortic regurgitation, the patient underwent aortic valve replacement. (bmj.com)
All patients experienced severe aortic regurgitation after leaflet laceration, but no patient required hemodynamic support in the 8 to 30 minutes between BASILICA and valve deployment, or afterward, Khan reported. (medscape.com)

In patients with a bicuspid aortic valve (BAV), these degenerative changes occur at an earlier age as a consequence of the abnormal hemodynamics across the valve leaflets. (medscape.com)
Bicuspid and unicuspid aortic valve disease are congenital conditions. (medscape.com)
Bicuspid and unicommissural unicuspid valves generally function normally for the first few decades, after which superimposed degenerative changes occur, at a faster rate that normal trileaflet aortic valves. (medscape.com)
For example, a patient must have a valve with three leaflets (tricuspid) rather than one with two leaflets (bicuspid). (samhealth.org)
As bicuspid aortic valve (BAV) affects ~1-2% of the population, it may be speculated that an increasing number of patients with degenerated BAV may eventually need TAVI during the course of the disease. (frontiersin.org)
Furthermore, considering the growing expansion of TAVI indications toward younger patients with higher prevalence of bicuspid AS, the clinical outcomes of TAVI in BAV warrant special attention ( 12 ). (frontiersin.org)
Calcium buildup of the valve happens sooner in people who are born with abnormal aortic or bicuspid valves. (medlineplus.gov)
Двостулковий аортальний клапан Bicuspid aortic valve is the presence of only two (rather than the normal three) valve cusps. (msdmanuals.com)
Bicuspid aortic valve is the most common congenital cardiovascular abnormality. (msdmanuals.com)

The medical/balloon aortic valvuloplasty group had a higher New York Heart Association functional class, incidence of renal failure, and lower ejection fraction. (nih.gov)
Increased BNP level was associated with a higher risk for AS-related adverse events in patients with asymptomatic severe AS with normal left ventricular ejection fraction who were not referred for AVR. (qxmd.com)
Using a decision tree algorithm, a Severe AS Index that estimates the likelihood that a patient with similar values would have severe AS diagnosed was developed from the training/validation dataset using AVA, JV, and MPG measurements, as well as left ventricular ejection fraction (LVEF) when available. (bostonsp.com)
On investigations it revealed concentric LVH with severe AS with moderate AR maintaining 60% ejection fraction. (anesthesiologypaper.com)
Severe, low flow, low-gradient aortic stenosis with reduced ejection fraction and evidence of flow (contractile) reserve excluding pseudo-severe aortic stenosis. (medtronic.com)
LF is a common finding within the aortic stenosis population and, in contrast to LV ejection fraction or mean pressure gradient, an independent predictor of all-cause and cardiovascular mortality. (omicsdi.org)
Flow-gradient patterns in severe aortic stenosis with preserved ejection fraction: clinical characteristics and predictors of survival. (omicsdi.org)
Among patients with severe aortic stenosis (AS) and preserved ejection fraction, those with low gradient (LG) and reduced stroke volume may have an adverse prognosis. (omicsdi.org)
A 90-year-old male with a past medical history of severe aortic stenosis, heart failure with reduced ejection fraction, and chronic kidney disease presents with shortness of breath. (emra.org)
With respect to patients with LVH and systolic dysfunction (ejection fraction less than 40 percent), evidence-based trials have led to the development of consensus guidelines for the management of heart failure. (aafp.org)

Among symptomatic patients with medically treated moderate-to-severe aortic stenosis, mortality from the onset of symptoms is approximately 25% at 1 year and 50% at 2 years. (medscape.com)
In July 2023, Cardiawave successfully completed the patient enrolment with no procedure or device-related mortality up to 30 days. (businesswire.com)
In patients with severe aortic stenosis (AS), atrial fibrillation (AF) is associated with increased long-term mortality after aortic valve replacement (AVR), which may be due to unfavorable hemodynamics in AF. (kssg.ch)
Patients with AF and SR had a different mPAWP-left ventricular end-diastolic pressure (LVEDP) relationship with higher mPAWP in AF and higher LVEDP in SR. After a median follow-up of 49 (interquartile range, 35-64) months post-AVR patients with AF (p = 0.05) and patients with a larger difference between mPAWP and LVEDP (p = 0.005) had higher mortality. (kssg.ch)
Patients with paradoxical LF-LG (35.0%), classic LF-LG (35.1%) and LF-high gradient (38.1%) had higher all-cause mortality at 3 years compared with NF-high gradient (24.8%) and NF-LG (27.9%) ( P =0.001). (omicsdi.org)
In their analysis, which was published October 3, 2018, in JAMA Cardiology , peak aortic velocity greater than 5 m/s and LVEF less than 60% were associated with an increased risk of all-cause and cardiovascular mortality without an aortic valve replacement procedure. (tctmd.com)
In fact, there's an appreciable mortality in patients with asymptomatic severe aortic stenosis. (tctmd.com)
Objective The purpose of this study is to describe recent mortality trends from aortic stenosis (AS) among eight high-income countries. (bmj.com)
In patients with severe stenosis, significant morbidity and mortality were experienced when aortic valve replacement was delayed beyond the postpartum period. (nih.gov)
A single study of patients with chronic heart failure has demonstrated that higher serum levels of cortisol are independent predictors of increased mortality risk. (druglib.com)
Evolut TAVI, now commercially launched in Europe, is now indicated for patients with severe native aortic stenosis who are at a low risk of surgical mortality. (massdevice.com)
All-cause mortality at 30-days was 1.6% for patients with AS+CAD treated with PCI compared to 2.9% for patients with AS alone (P = 1). (bvsalud.org)

Progressive calcific degeneration of the trileaflet aortic valve is the most common cause of AS, especially in the elderly population. (medscape.com)
Hemodynamic and clinical improvements statistically demonstrated in high-risk patients with calcific aortic stenosis (CAS). (businesswire.com)
The study, entitled "Prospective, Single-arm Pivotal Study for the Treatment of Subjects with Severe Symptomatic Calcific Aortic Valve Stenosis Using Valvosoft® Non-Invasive Ultrasound Therapy", successfully enrolled 60 patients at 11 clinical sites in France, Germany and the Netherlands and marks a significant milestone in the development of Cardiawave's medical advances, paving the way for CE marking of the device. (businesswire.com)
Calcific aortic stenosis has been also termed "degenerative aortic stenosis" and "fibrocalcific aortic stenosis. (medscape.com)
Calcific aortic valve disease occurs on previously normally-functioning valves, either bi- or trileaflet, and less commonly on unicuspid valves. (medscape.com)
Patients with severe calcific degenerative aortic stenosis can be categorized into three clinical groups at the time of diagnosis: those without evidence of congestive heart failure, those with chronic congestive heart failure, and those with acute heart failure requiring hospitalization. (medscape.com)
This is called calcific aortic stenosis. (medlineplus.gov)

Importance: Medically treated symptomatic severe aortic stenosis has poor outcomes, and in the past 6 decades, it has successfully been treated with surgical aortic valve replacement (SAVR). (wustl.edu)
However, one-third of patients with indications for SAVR are not offered surgery because of the high risk of complications. (wustl.edu)
Subsequent trials showed both balloon-expandable and self-expandable valves to have good results in high-risk, medium-risk, and low-risk surgical patients when compared with SAVR. (wustl.edu)
1-4 Owing to the substantial differences in invasiveness between TAVI and SAVR, major bleeding complications and packed red blood cell (PRBC) transfusions have been shown to be 2 to 3 times less frequent among patients undergoing TAVI, com- pared to those undergoing SAVR, in the PARTNER trial. (123dok.net)
After discussion with the surgeons and his family, the patient is worried about the risk of open heart surgery as well as high morbidity associated with surgical aortic valve replacement (SAVR) based on his STS scores. (acc.org)
Clinical data from a global, randomized trial that evaluated three valve generations against surgical valve replacement (SAVR) in more than 1,400 patients revealed that TAVI is an effective treatment for low-risk patients, improving 30-day quality-of-life scores compared to SAVR. (massdevice.com)

The only definitive treatment for aortic stenosis in adults is aortic valve replacement (surgical or percutaneous). (medscape.com)

Over time, inflammation, atherosclerosis and calcification thicken the aortic valve leaflets and restrict mobility. (medscape.com)
Regardless of the etiology, calcification of the aortic valve leads to stenosis, inevitably resulting in a fixed obstruction to LV emptying. (medscape.com)
Acquired stenosis of the aortic valve, which affects adults, is most often caused by calcification of the leaflets themselves and is considered an age-related or degenerative process. (medscape.com)
Hardening of the aortic valve, usually by degenerative calcification, with a jet velocity of less than 5 mm/second is considered aortic sclerosis and is asymptomatic. (medscape.com)
At present, the most common cause of valve replacement in the United States is aortic stenosis secondary to calcification. (medscape.com)
She was diagnosed with severe stenosis of aortic valve, with extensive valve calcification. (yashodahospitals.com)
Lipid deposition and inflammation lead to thickening of aortic valve structures by fibrosis and calcification initially without causing significant obstruction. (msdmanuals.com)

The pathologic findings, clinical symptoms, and treatment are similar to degenerative aortic stenosis in trileaflet valves. (medscape.com)
[ 3 ] Degenerative aortic stenosis is currently the most common indication for valve surgery, as the population ages and newer techniques, such as minimally invasive surgery and transcutaneous methods, become available. (medscape.com)

In conclusion, if CPET does not indicate a significant hemodynamic compromise because of aortic stenosis, an initially conservative strategy results in a good prognosis and an acceptable event rate. (cpxinternational.com)
We aimed to analyze the hemodynamic profile of patients with severe AS and AF versus sinus rhythm (SR). (kssg.ch)
Patients with severe AS and concomitant AF have a distinct and significantly worse hemodynamic profile compared to patients with SR associated with worse clinical outcome. (kssg.ch)
Forty-eight hours later, the patient had paroxysmal atrial fibrillation and a temperature of 39°C, with severe hemodynamic and respiratory impairment. (cdc.gov)
Additionally, Evolut displayed superior hemodynamic performance with lower mean aortic valve gradients and larger effective orifice areas compared to surgery at one year. (massdevice.com)

Aortic stenosis can be caused by acquired conditions, be the result of a congenital malformation, or be a result of a combination of acquired and congenital processes. (medscape.com)
Congenital aortic stenosis is classified as valvular, subvalvular, and supravalvular. (medscape.com)
Congenital aortic stenosis becomes symptomatic in childhood. (medscape.com)
Aortic stenosis may be present from birth (congenital), but most often it develops later in life. (medlineplus.gov)
All patients critical for the comprehensive and optimum were finally diagnosed in the main referral care of congenital heart disease population institutes. (who.int)
A significant number of referrals (234 are also considered of pivotal importance of 974, i.e. around 24% in the Al Hasaa for groups which care for patients with study) were normal and excluded from the congenital heart disease as well as for poli- study. (who.int)

Invasive aortic and left ventricular pressure waveforms were obtained simultaneously before and after the TAVI. (atlantis-press.com)
Methods and Results--Between August 2007 and April 2012, 489 consecutive patients with severe aortic stenosis were included into the Bern-TAVI-Registry. (123dok.net)
Thus, TAVI procedure risks are minimal and patients can recover quickly without any postoperative side-effects. (yashodahospitals.com)
Peculiar features such as larger dimensions of the aortic valve components, higher calcium burden, presence of a heavily calcified raphe, and associated aortopathy represent some pitfalls when treating BAV patients with TAVI. (frontiersin.org)
However, the unique morphological features of BAV and the lack of consensus on the optimal sizing technique pose a challenge when offering TAVI to such patients. (frontiersin.org)
20 ) proposed a new classification for BAV based on multi-slice computed tomography (MSCT) imaging, taking in account the increasing role of TAVI in such patients. (frontiersin.org)
The aim of the present investigation was to determine the incidence, risk factors for, clinical presentation of, and outcome after prosthetic valve endocarditis (PVE) in patients treated with TAVI in a nationwide study. (lu.se)
In the context of PVE, TAVI seems to be a safe option for patients. (lu.se)
Comparison of early and late outcomes of TAVI alone compared to TAVI plus PCI in aortic stenosis patients with and without coronary artery disease. (bvsalud.org)
Patients with severe symptomatic aortic stenosis (AS) (n = 249) that underwent TAVI were divided into two groups patients with CAD (subdivided to patients treated with TAVI alone and to patients that underwent PCI before TAVI) and patients with isolated AS. (bvsalud.org)
Of a cohort of 249 consecutive patients with mean age of 83.2 ± 5.5 years, 83 patients with AS + CAD were treated with TAVI alone, 61 patients with AS + CAD underwent PCI before TAVI and 105 patients underwent TAVI for isolated AS. (bvsalud.org)
Performing PCI before TAVI in high- risk elderly patients with significant CAD and severe AS is feasible and safe. (bvsalud.org)

In response to the progressive narrowing of the aortic valve opening, the LV myocardium becomes hypertrophic in order to generate increased pressure during systole and thus force blood past the obstruction. (medscape.com)
Aortic stenosis (AS) is narrowing of the aortic valve, obstructing blood flow from the left ventricle to the ascending aorta during systole. (msdmanuals.com)

The evolving epidemiology of valvular aortic stenosis. (acpjournals.org)
This is particularly possible in those with valvular aortic stenosis after valve replacement. (aafp.org)

The approach to managing asymptomatic or questionably symptomatic patients for aortic stenosis is difficult. (cpxinternational.com)
AVR is recommended for symptomatic patients but the timing of surgery is critical to optimise outcome. (gla.ac.uk)

Background Development of left ventricle (LV) hypertrophy in aortic stenosis (AS) is accompanied by adaptive coronary flow regulation. (bmj.com)
We aimed to assess absolute coronary flow, microvascular resistance, coronary flow reverse (CFR) and microvascular resistance reserve (MRR) in patients with and without AS. (bmj.com)
Methods Absolute coronary flow and microvascular resistance were measured by continuous thermodilution in 29 patients with AS and 29 controls, without AS, matched for age, gender, diabetes and functional severity of epicardial coronary lesions. (bmj.com)
Conclusions In patients with severe AS and non-obstructive coronary artery disease, with the progression of LV hypertrophy, the compensatory mechanism of increased resting flow maintains adequate perfusion at rest, but not during hyperaemia. (bmj.com)
Angiography shows right dominant coronary anatomy with 40% stenosis of the mid left anterior descending artery and 30% stenosis of the proximal right coronary artery. (acc.org)
Valve replacement is also recommended if the patient is undergoing concomitant valve or coronary surgery or has induced symptoms on a treadmill stress test. (tctmd.com)
The stenotic aortic valve results in a buildup of pressure inside the left ventricle and a comparably lower pressure in the aortic root, resulting in low coronary perfusion pressure. (emra.org)
Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of amlodipine, particularly in patients with severe obstructive coronary artery disease. (nih.gov)
Patients with LVH tend to be older and more obese, have higher blood pressure and be more likely to have preexisting coronary artery disease and depressed left ventricular systolic function. (aafp.org)
The clinical unit is located at the Department of Cardiology and focuses on prospective studies of patients with ST-elevation myocardial infarction (STEMI) who are treated with primary percutaneous coronary intervention. (gu.se)
Intervention group: patients with slow flow coronary arteries in angiography will be treated with standard medicine for two weeks and in case of pain continuation, will be treated with oral pentoxifylline 400 milligram three times a day for two weeks and finally pentoxifylline effect in chest pain reduction will be evaluated. (who.int)
In line with the ageing population, the prevalence of coronary artery disease (CAD), lower extremity peripheral arterial disease (PAD), supra-aortic arterial disease (SAD) and renal stenosis (RAS) is increasing. (who.int)
The procedure, called BASILICA, involves an electrified guidewire that traverses and lacerates the aortic leaflet in front of the coronary artery at risk for obstruction, so that the split leaflet splays out of the way once the valve is deployed. (medscape.com)
There was no evidence of coronary obstruction, and no patient had more than mild paravalvular leak. (medscape.com)

The heart sounds S1 and S2 were audible with an ejection systolic murmur at the aortic area. (bmj.com)
Physical examination showed a systolic murmur and an echocardiogram showed aortic stenosis. (cdc.gov)

A patient with severe aortic stenosis and hyperopia had no atherosclerosis but a confluence of SDD and no drusen. (medpagetoday.com)
The cause of aortic sclerosis and stenosis is not yet known but is mediated by an inflammatory process that is similar to but distinct from atherosclerosis. (msdmanuals.com)
Lipoprotein (a) is implicated in the pathogenesis of both aortic stenosis and atherosclerosis. (msdmanuals.com)
are at increased risk for atherosclerosis, and more recently, psoriasis has been tied to an increased risk of aortic stenosis. (msdmanuals.com)

Spectroscopic measurements of myocardial triglyceride content correlated significantly with histological analysis of biopsies obtained during aortic valve replacement. (ox.ac.uk)

Clinically, the patients experienced a considerable improvement in their clinical status suggesting a better quality of life. (businesswire.com)
In June 2022, following the positive results of our FIH clinical studies, Cardiawave started a pivotal study on severe symptomatic aortic valve stenosis patients who refuse (in Germany and Netherland) or were not recommended for valve replacement. (businesswire.com)
Cardiawave would like to express its gratitude to the patients who took part in this clinical study, and to the medical teams and researchers who helped make it possible. (businesswire.com)
Here, a Diagnostic Precision Algorithm was developed from a de-identified dataset of 1,147,157 echocardiographic reports from 35 institutions to help physicians identify patients who may have incorrectly not received a severe AS diagnosis and prioritize these findings for secondary clinical review. (bostonsp.com)
Most patients in clinical trials were treated with doses of 16 mg/hour or less. (wikipedia.org)
In clinical studies, no significant changes occurred in serum triglyceride levels in the Cleviprex treated patients. (wikipedia.org)
One of the most important clinical challenges in these three categories of patients with LG AS (classical LF-LG, paradoxical LF-LG, and NF-LG) is to differentiate a true-severe AS that generally benefits from AVR vs. a pseudo-severe AS that should be managed conservatively. (omicsdi.org)
An active follow-up means we need to clearly follow patients and identify any occurrence of symptoms or clinical deterioration. (tctmd.com)
The American Heart Association (AHA) and American College of Cardiology (ACC) recommend a watch-and-wait approach that includes serial clinical and echocardiographic examinations for patients with asymptomatic AS. (tctmd.com)
To TCTMD, Lancellotti said they selected heart valve centers because they wanted to accurately identify the natural history of asymptomatic AS in patients who would be stringently followed over time and managed and/or treated according to the clinical guidelines. (tctmd.com)
Left ventricular hypertrophy (LVH) is a common clinical problem, and the number of patients with LVH is increasing. (aafp.org)
If indeed, hair cortisol and testosterone levels would correlate with heart failure status, they may be used as a quantitative mode for clinical follow-up of CHF patients (similar to the role of HbA1C in the follow-up of diabetic patients). (druglib.com)
In clinical practice, once all this has been formulated and codified, it is possible that we could have these fairly inexpensive retinal cameras available through[out] the medical world so that patients can be screened by them as part of their routine medical care," Smith told MedPage Today . (medpagetoday.com)
That said, he continued, "long-term durability assessments of transcatheter bioprosthetic valves are still lacking and extrapolation of these findings to low-risk patients requires further clinical trial evaluation. (tctmd.com)
Early data suggest that stroke rates are even lower with the lower-profile Sapien 3 device (Edwards Lifesciences), which is the subject of another late-breaking clinical trial presentation tomorrow, also in intermediate-risk patients. (tctmd.com)
As a clinical cardiologist, she believes strongly in the tenets of evidence-based practice, diagnostic cognizance, and patient education. (stanford.edu)

We sought to evaluate the prognostic impact of the B-type natriuretic peptide (BNP) levels in patients with asymptomatic severe aortic stenosis (AS), who were not referred for aortic valve replacement (AVR). (qxmd.com)

The group of 34 patients (age 60-90 years, 17 women and 17 men) with severe AS and 50 healthy controls (age 61-85 years, 29 women and 21 men) underwent MRI brain examinations, which were analysed for the neuroradiological indices of brain atrophy. (polradiol.com)

Hypovolemia and supraventricular tachyarrhythmias (eg, atrial fibrillation) dramatically reduce left ventricular preload and are tolerated poorly in this patient population. (emra.org)
Facilitation of atrioventricular conduction has been observed in human electrophysiologic studies and in patients with atrial fibrillation. (drugs.com)
by contrast, surgery-treated patients had more acute kidney injury, severe bleeding, and new-onset atrial fibrillation. (tctmd.com)
Given the now substantial body of knowledge regarding the fetal physiology and natural history of these lesions in utero and the success of balloon aortic and pulmonary valvuloplasty in preventing or reversing newly onset ventricular dysfunction postnatally in infants, there is a theoretical rationale for intervention to relieve valvar stenosis or to enlarge a restrictive atrial septal opening in fetal life. (medscape.com)
Modification of early techniques has since allowed percutaneous access for catheter-based interventions and has met with technical success, not only in fetal aortic valve stenosis but also in pulmonic valve atresia and stenosis and in hypoplastic left heart syndrome (HLHS) with an intact or highly restrictive atrial septum. (medscape.com)

Anticipate hypotension in volume-or salt-depleted patients with treatment initiation. (nih.gov)
Symptomatic hypotension is possible, particularly in patients with severe aortic stenosis. (nih.gov)

We used data from a Japanese multicentre registry, the Contemporary outcomes after sURgery and medical tREatmeNT in patients with severe Aortic Stenosis Registry, which enrolled 3815 consecutive patients with severe AS. (qxmd.com)
Missed diagnosis of severe AS can lead to a delay in treatment and poor outcomes, but there are limited tools available to help physicians minimize the risk of missed diagnoses. (bostonsp.com)
Although patients with LF-LG severe AS have worse outcomes than those with high-gradient AS following AVR, they nonetheless display an important survival benefit with this intervention. (omicsdi.org)
But with asymptomatic patients, we don't know when to intervene or if we intervene whether it would be associated with improved outcomes. (tctmd.com)
The researchers analyzed outcomes from 1,375 patients treated at dedicated heart valve centers in Europe, Canada, and the United States between 2001 and 2014. (tctmd.com)
In late December 2021, COVID-19, is critical to preventing COVID-19-associated the B.1.1.529 (Omicron) variant of SARS-CoV-2 (the virus that hospitalization and severe outcomes. (cdc.gov)

In six patients, bioprosthetic aortic valves had failed, and one patient had native aortic stenosis . (medscape.com)

In severe aortic stenosis, the carotid arterial pulse typically has a delayed and plateaued peak, decreased amplitude, and gradual downslope (pulsus parvus et tardus). (medscape.com)

Improved valve function was confirmed at 6 months, reflected by a 10% increase in mean aortic valve area and by quality-of-life improvements. (businesswire.com)

Blood flows out of the heart and into the aorta through the aortic valve. (medlineplus.gov)
Коарктація аорти Coarctation of the aorta is a localized narrowing of the aortic lumen that results in upper-extremity hypertension, left ventricular hypertrophy, and malperfusion of the abdominal organs and. (msdmanuals.com)

22 ± 8 vs. 15 ± 7 mmHg), and pulmonary vascular resistance (2.8 ± 1.9 vs. 2.0 ± 1.3 Wood units) and lower stroke volume index (26 ± 9 vs. 37 ± 10 ml/m) than patients with SR (p (kssg.ch)
Hemodynamically significant AS must be on the differential in the undifferentiated patient presenting with acute pulmonary edema, syncope, or cardiogenic shock , particularly if they are elderly. (emra.org)

The prognosis is especially poor in the setting of acute heart failure, for which aortic valve replacement provides the least benefit. (medscape.com)
However, this study included patients with heart failure who were admitted to the hospital due to other causes and it might be speculated that the single serum cortisol measurement taken may have been influenced by the acute illness or by the emotional stress associated with the admission itself. (druglib.com)
We have recently demonstrated higher hair cortisol levels in patients with acute myocardial infarction compared with controls (the manuscript has been submitted for publication). (druglib.com)
However, the patient developed septic shock, adult respiratory distress syndrome, and oliguric acute renal failure, and died of multiple organ failure. (cdc.gov)

2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (acpjournals.org)
To assess the prevalence of the neuroradiological indices of brain atrophy in patients with severe aortic valve stenosis (AS) in magnetic resonance imaging (MRI) with particular emphasis on the assessment of atrophy areas typical of cerebral small vessel disease (CSVD). (polradiol.com)
Severe aortic stenosis (AS) remains a life-threatening form of valvular heart disease. (bostonsp.com)
The Diagnostic Precision algorithm was highly accurate at identifying the likelihood of severe AS diagnosis and applying this information to prioritize physician follow-up for patients who may have undiagnosed severe disease. (bostonsp.com)
Coexistence of both intracranial aneurysm and aortic stenosis is quiet rare but it may complicate management of either disease. (anesthesiologypaper.com)
See also Aortic Stenosis , Pediatric Valvar Aortic Stenosis , Pediatric Rheumatic Heart Disease , and Pathology of Rheumatic Heart Disease . (medscape.com)
Aortic sclerosis, which is clinically defined as valve thickening without obstruction to outflow, is the most prevalent valve disease in developed countries, being present in about 25% of patients over age 65 years. (medscape.com)
The incidence of symptomatic stenosis, a more advanced form of sclerosis that causes symptoms, is approximately 5 in 10,000 and is generally a disease of the elderly. (medscape.com)
This is a functional nonagenarian with multiple comorbidities including previous cerebrovascular accident, obesity, hypertension, diabetes mellitus type 2, hyperlipidemia, obstructive sleep apnea and chronic kidney disease stage 3, in addition to his advanced age, which contribute to the high-surgical risk of isolated aortic valve replacement in this patient. (acc.org)
Critical aortic stenosis (AS) is the single most problematic valvular disease we encounter in the emergency department. (emra.org)
50 mmHg indicates severe disease. (emra.org)
3-5 However, it is important to note that a substantial proportion of patients with severe and critical AS have a low gradient, which most frequently results from the decreased stroke volume associated with advanced disease. (emra.org)
Aortic stenosis (AS) is a critical disease without structural treatment. (bmj.com)
The concept of chronic disease self-management programmes together with the emerging expert patient has not been widely studied in the context of heart disease. (bjcardio.co.uk)
But many of our patients with chronic heart disease are already experts. (bjcardio.co.uk)
It has also been acknowledged in the report 'The expert patient: a new approach to chronic disease management for the 21st Century',2 which recommends action over a six-year period to introduce lay led self-management training programmes for patients with chronic diseases within the NHS in England. (bjcardio.co.uk)
Investigators hypothesized that high-risk CVD -- including myocardial infarction (MI), valvular disease, and internal carotid artery stenosis (ICA) -- are strongly associated with SDDs but not drusen. (medpagetoday.com)
Aortic stenosis is an increasingly common and serious valve disease in which the aortic valve becomes narrow, and blood is not adequately pumped through the heart," said Cardiologist Edward Toggart, MD . "The most common cause is the buildup of calcium deposits on the valve leaflets. (samhealth.org)
Medtronic is well positioned to provide a variety of therapy options to meet the varying needs of patients with heart valve disease. (massdevice.com)
AS was classified by both disease (mild/severe) severity and symptomatic (Sy/Asy) status. (gla.ac.uk)
Most people with aortic stenosis do not develop symptoms until the disease is advanced. (medlineplus.gov)
Several previous reports suggest a A total of 2604 patients, 1299 males changing pattern and incidence of congeni- and 1305 females, age range 0-13 years, tal heart disease in various geographic loca- were evaluated in the studies. (who.int)
Patients with acquired heart disease cymakers. (who.int)

2022). Artificial intelligence to assist physicians in identifying patients with severe aortic stenosis. (bostonsp.com)
On April 19, 2022, this report was posted as an MMWR Early obesity were more likely to experience severe COVID-19. (cdc.gov)

Patients with severe heart failure due to aortic stenosis that is resistant to medical management should be considered for urgent surgery. (medscape.com)
Spironolactone can be considered in patients with advanced heart failure. (aafp.org)
The purpose of this study is to determine whether hair cortisol and testosterone levels correlate with heart failure status in patient with chronic congestive heart failure. (druglib.com)
Regarding testosterone, several studies have recently demonstrated lower free serum testosterone levels in patients with heart failure compared with controls. (druglib.com)
Left untreated, severe aortic stenosis can lead to heart failure and death. (samhealth.org)
Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure. (cdc.gov)

The concept of performing balloon valvuloplasty in fetuses with stenotic heart valves followed the successful introduction of neonatal balloon valvuloplasty in the 1980s, with the first reported case performed in a fetus with aortic stenosis in 1989. (medscape.com)

Subjects and Methods: We analyzed 41 patients (24 males, 63.1±8.7 years) with preserved LV systolic function who were scheduled to undergo AVR for severe AS. (elsevierpure.com)

Postrheumatic aortic stenosis is another common cause of acquired aortic stenosis, and is a result of remote infection from group A streptococci that triggers an autoimmune process resulting in scarring of the valve leaflets. (medscape.com)
Notably, two leaflets were lacerated in one of the seven patients. (medscape.com)

Aortic stenosis is the obstruction of blood flow across the aortic valve (see the image below). (medscape.com)

CONCLUSIONS: Pronounced myocardial steatosis is present in severe AS, regardless of symptoms, and is independently associated with the degree of LV strain impairment. (ox.ac.uk)

Greater jet flow velocity with a gradient of less than 20 mm Hg is considered mild stenosis. (medscape.com)
Children with mild or moderate aortic stenosis may get worse as they get older. (medlineplus.gov)

Patients who receive prolonged Cleviprex infusions and are not transitioned to other antihypertensive therapies should be monitored for the possibility of rebound hypertension for at least 8 hours after the infusion is stopped. (wikipedia.org)

Led by Dr. Nicholas Schiff, the study looked at five people with moderate to severe brain injuries. (massdevice.com)
After a 2-d echo showed moderate to severe aortic stenosis. (heart-valve-surgery.com)

Trileaflet calcified aortic valve with severe AS with mean gradient of 55 mm Hg, peak velocity of 4.8 m/sec and aortic valve area of 0.9 cm 2 . (acc.org)
Peak aortic velocity and LVEF can help physicians select asymptomatic patients who might benefit from an early AVR intervention. (tctmd.com)

In fact, qualitative assessment of the aortic valve from the parasternal long and short axis views has been shown to be 75% sensitive and 93% specific for the diagnosis of severe AS among trained emergency medicine providers. (emra.org)

Anatomy8

Diseases51

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment68

Phenomena and Processes20

Information Science2

Named Groups1

Health Care25

Transcatheter aortic valve35

Implantation1

Indexed aortic valve1

TAVR42

Cardiac19

Echocardiography5

Regurgitation4

Bicuspid9

Ejection Fraction10

Mortality12

Calcific7

SAVR6

Treatment for aortic stenosis1

Calcification7

Degenerative aortic stenosis2

Hemodynamic5

Congenital6

TAVI12

Narrowing of the aortic valve2

Valvular aortic stenosis2

Symptomatic patients2

Coronary14

Systolic murmur2

Atherosclerosis4

Obtained during aortic valv1

Clinical16

Referred for aortic valve repla1

Underwent1

Atrial5

Hypotension2

Outcomes6

Native aortic1

Arterial1

Mean aortic valve1

Aorta2

Pulmonary2

Acute4

Disease23

20222

Heart failure6

Valvuloplasty1

Methods1

Leaflets2

Obstruction1

Conclusions1

Mild2

Therapies1

Moderate-to-severe2

Velocity2

Diagnosis1