• in the meanwhile, "a tailor-made management by a heart team in specialised heart valve clinics is recommended in patients with asymptomatic severe AS, with thorough risk stratification, patient education and close follow-up. (bmj.com)
  • Patients with asymptomatic severe AS and an LV ejection fraction of 50% or higher are recognized as Stage C1 AS and those with LV systolic dysfunction are recognized as Stage C2 AS. (acc.org)
  • (1) , who reported that a strategy of earlier aortic valve replacement (AVR) in patients with asymptomatic severe aortic stenosis (AS) was associated with a lower long-term risk of hospitalization for heart failure or all-cause mortality compared with the strategy currently recommended in clinical practice guidelines, which is to wait for the onset of symptoms before intervention. (onlinejacc.org)
  • Among patients with asymptomatic severe AS, cardiopulmonary exercise testing (CPET) provides more sensitive detection of exercise intolerance than the stress test criteria recommended in the guidelines (3) . (onlinejacc.org)
  • In comparison, in patients with conventionally defined severe AS, orifice area by echo/Doppler was 0.72 ± 0.17 cm 2 and by catheterization 0.51 ± 0.15 cm 2 (oxymetry) and 0.68 ± 0.21 cm 2 (thermodilution), respectively, and mean systolic gradient 51 ± 10 mm Hg and 55 ± 8 mm Hg, respectively. (acc.org)
  • The authors concluded that low-gradient severe AS despite preserved EF was confirmed by invasive hemodynamics, and was not the result of a systematic bias in the echo/Doppler calculation of aortic orifice area. (acc.org)
  • However, because echo/Doppler effective orifice area (EOA) is subject to error in calculation, controversy has existed as to whether low-flow low-gradient severe AS and paradoxical normal LVEF is mostly due to error in echo/Doppler calculation of EOA rather than genuine pathophysiology. (acc.org)
  • Because the abnormal architecture induces turbulent flow, it traumatizes the leaflets and leads to fibrosis, increased rigidity, and calcification of the leaflets, which ultimately results in the narrowing of the aortic orifice. (nih.gov)
  • While the individual areas of each orifice were consistent with severe AS, the effective total AVA by planimetry was 1.3 cm 2 [Figure . (scmr.org)
  • This case represents an overestimation of the severity of AS by TTE due to unusual dual orifice aortic valve anatomy that was ultimately defined on CMR. (scmr.org)
  • Ascending aortic diameter was significantly smaller in the "paradoxical" AS group than in patients with conventionally defined severe AS (28 ± 5 mm vs. 31 ± 5 mm), and energy loss index was significantly larger (0.51 ± 0.12 cm 2 /m 2 vs. 0.42 ± 0.09 cm 2 /m 2 , respectively). (acc.org)
  • We evaluate all aspects of AS quantitation in reference to paradoxical low flow aortic stenosis and discuss newer parameters which may help the clinician reconcile some of the discrepancies of this less understood condition. (biomedsearch.com)
  • Prospective cohort study to test the hypothesis that patients identified with severe aortic stenosis are under-diagnosed and under-treated. (bioportfolio.com)
  • So you know, I suffered from aortic stenosis due to a bicuspid valve with calcified leaflets. (heart-valve-surgery.com)
  • The morphology of the aortic valve, including aortic valve leaflets, free edges, and annuli, can be assessed in parallel and perpendicular planes at the mid-systolic phase (i.e., open valve) and at the mid-diastolic phase (i.e., closed valve) using multiplanar reformation and double-oblique reformations (Fig. 1) on an ECG-gated MDCT. (nih.gov)
  • An ECG-gated MDCT has the ability to accurately depict these morphologic abnormalities of the aortic valve (10-12). (nih.gov)
  • TTE Doppler of velocity through aortic valve and subsequent calculations of gradients and AVA. (scmr.org)
  • The diagnostic features include a poorly contracting left ventricle, aortic valve thickening/restriction, a varying degree of left ventricular hypertrophy and abnormal Doppler flow characteristics in the left heart. (wikipedia.org)