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Diacylglycerol O-AcyltransferaseSesquiterpenesMolecular Sequence DataSesquiterpenes, GermacraneSesquiterpenes, EudesmaneLactonesCarbon-Carbon LyasesSesquiterpenes, GuaianeAsteraceaeAlkyl and Aryl TransferasesFerulaVernoniaPolyisoprenyl PhosphatesArtemisia annuaMolecular StructureInulaTanacetum partheniumSaussureaPlant ExtractsChicoryPlant Components, AerialHyoscyamusLaurusMonoterpenesTerpenesCyclizationStereoisomerismDysideaMagnetic Resonance SpectroscopyPlants, MedicinalChrysanthemum cinerariifoliumCoprinusGeranyltranstransferaseCentaureaOils, VolatilePoriferaProtein BiosynthesisTanacetumTrichomesSantoninGas Chromatography-Mass SpectrometrySolanumVerticilliumKineticsCelastraceaeCelastrusIntramolecular LyasesEscherichia coliAristolochiaceaeGlycosidesRNA, MessengerCycloheptanesEuonymusProtein Synthesis InhibitorsTaraxacumPlant LeavesCyclopentanesAchilleaIsomerasesAmino Acid SequenceCells, CulturedFarnesolFuransBicyclo CompoundsDNACalendulaChamaecyparisBase SequenceVolatilizationRhizomePlant ProteinsHippocrateaceaeDrug Screening Assays, AntitumorHelianthusPlant RootsWikstroemiaPlant BarkCell LineNaphtholsLinderaStructure-Activity RelationshipOxylipinsLamiaceaeHepatophytaPhaeophytaPeperomiaGene Expression Regulation, PlantDiterpenesBiosynthetic PathwaysCycloheximideCloning, MolecularArnicaDennstaedtiaceaeLettuceBombaxCatalysisLiriodendronInflorescenceDNA ReplicationGossypium
BiosynthesisSynthaseLactonesCytochromeCompoundsSecondary metabolitesVolatileTerpeneNomenclatureExtractsOxidationConstituentsFlavoursPathwayPeptidesCofactorsDerivativesPotentCarbohydrateReactionsPyruvatePrecursorsProteinsChemicalExtractionBiologicalBacterialAlkaloidsNaturallySimplicityMetabolismActivityFunctionsStemProductionNatural productsCancerFormationDesignCreateLeads
Biosynthesis7
  • This biosynthesis can be mimicked in the laboratory by preparing allylic stannane from farnesol, termed Corey synthesis. (wikipedia.org)
  • Knowledge about the central steps of diterpene formation in coffee provides a foundation for future characterization of the subsequent enzymes involved in CAF and KAH biosynthesis. (bvsalud.org)
  • The first committed enzyme in triterpene saponin biosynthesis from A. mongolicus , cycloartenol synthase (AmCAS), which belongs to the oxidosqualene cyclase family, was cloned by us to study the astragalosides biosynthesis. (biomedcentral.com)
  • Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in Pseudo-Aspidosperma alkaloid biosynthesis. (mpg.de)
  • Two bi-functional cytochrome P450 CYP72 enzymes from olive (Olea europaea) catalyze the oxidative C-C bond cleavage in the biosynthesis of secoxy-iridoids - flavor and quality determinants in olive oil. (mpg.de)
  • their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. (dattanibookagency.in)
  • Microbial toluene biosynthesis was reported in anoxic lake sediments more than three decades ago, but the enzyme catalyzing this biochemically challenging reaction has never been identified. (jbei.org)
Synthase4
  • HlRLS alleles produced ( R )-(-)-linalool, whilst alleles of two sesquiterpene synthase genes, HlAFS1 and HlAFS2 produced α-farnesene. (biomedcentral.com)
  • Furthermore, the substrate scope of the 2-methylisoborneol synthase was investigated through enzyme incubations with several substrate analogs, giving access to two C12 monoterpenoids. (journaltocs.ac.uk)
  • Then, two IPPs and one dimethylallyl pyrophosphate (DMAPP) are transformed to farnesyl diphosphate (FPP), which is precursor for all sesquiterpenes, through farnesyl diphosphate synthase (FPS). (springeropen.com)
  • Afterward, sesquiterpene synthase converted FPP to sesquiterpenes, which are further modified by oxidation reactions using cytochrome P450 enzymes. (springeropen.com)
Lactones3
  • New guaianolide sesquiterpene lactones and other constituents from Pyrethrum pulchrum. (mpg.de)
  • Bioactivity-Guided Isolation of Antiproliferative Sesquiterpene Lactones from Centaurea solstitialis L. ssp. (eurekaselect.com)
  • Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention. (who.int)
Cytochrome1
  • Endeavour worked with Oxford Biotrans to determine whether their novel, custom-designed cytochrome P450 enzymes are able to produce the 'peppery' sesquiterpine Rotundone (FEMA No. 4867) from a sustainable, natural source. (endeavourchem.co.uk)
Compounds4
  • This work provides valuable resources for bioengineering and in vitro synthesis of the natural compounds for medical research and for potential drug development. (biomedcentral.com)
  • Parthenolide (PN) is a main bioactive molecule in feverfew which belongs to sesquiterpene lactone compounds. (springeropen.com)
  • Flavours and fragrances represent over a quarter of the world market and most of the flavouring and perfume compounds are produced through chemical synthesis or by extraction from natural materials like plant and animal sources. (medcraveonline.com)
  • TrMTs are sesquiterpene compounds consisting of three rings with an epoxide ring at the C-12-C-13 atoms and a double bond at the C-9-C-10 atoms: so, the group is called 12,13-epoxy-trichotec-9-ens. (actanaturae.ru)
Secondary metabolites1
  • 2017 ). Secondary metabolites (SMs) have complex structures to be manufactured by chemical synthesis and thus frequently extracted from naturally grown or cultivated plants (Deepthi and Satheeshkumar 2016 ). (springeropen.com)
Volatile1
  • In the last decade Petunia hybrida has emerged as the model of choice to study volatile benzenoid and phenylpropanoid synthesis, emission and regulation. (uva.nl)
Terpene2
  • An extremely recent research, using the brand new technique of genome mining [24], also unveils remarkable biosynthetic potential of many bacterial types for terpene synthesis. (abt-888.net)
  • This makes the flavonoid and terpene synthesis more efficient, increasing their values by several percentage points. (potlovesme.com)
Nomenclature1
Extracts1
  • The chapters in this volume are written by eminent authorities in the field and are mainly focused on inhibition of monoamine oxidase (MAO) via green tea extracts, cynaropicrin as an inhibitor of Bcr-Abl fusion oncogene expression, effects of dietary polyphenols on chronic diseases, taxol production, mushroom functionalities in cancer treatment, and health related enzyme inhibiting natural products. (benthambooks.com)
Oxidation2
  • A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (lookformedical.com)
  • Enzymes that catalyze the cleavage of a carbon-carbon bond by means other than hydrolysis or oxidation. (lookformedical.com)
Constituents1
Flavours1
  • Flavours are generally used as food additives and they are mostly produced through artificial means i.e. chemical synthesis or by extraction from plant and animal sources. (medcraveonline.com)
Pathway2
  • Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. (easyomics.org)
  • The crystal structures and biochemical characterization of the NAD-dependent dehydrogenases [LigD (PDB IDs 4Y98 4Y9D ), LigO (PDB IDs 4YA6 4YAC ), and LigL (PDB IDs 4YAE 4YAG 4YAI )] and the glutathione-dependent lyase LigG (PDB IDs 4YAP 4YAV ) provide new insights into the early and late enzymes in the β-ether degradation pathway. (jbei.org)
Peptides1
Cofactors1
  • The gel-like solution of enzymes, substrates, cofactors, and ions in the interior of the mitochondrion. (flashcardmachine.com)
Derivatives1
  • Design, synthesis and biological evaluation of pteridine-7(8H)-one derivatives as potent and selective CDK4/6 inhibitors. (ecust.edu.cn)
Potent2
  • Design, synthesis and biological evaluation of potent and selective S1PR1 agonists for the treatment of Ulcerative Colitis. (ecust.edu.cn)
  • From wine to pepper: rotundone, an obscure sesquiterpene, is a potent spicy aroma compound. (endeavourchem.co.uk)
Carbohydrate2
  • the site of carbohydrate synthesis. (flashcardmachine.com)
  • The inner membrane encloses the stroma, a concentrated solution of enzymes, including those required for carbohydrate synthesis. (flashcardmachine.com)
Reactions1
  • The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. (dattanibookagency.in)
Pyruvate1
  • This is facilitated by glycolytic enzymes such as the M2 isoform of pyruvate kinase (PKM2) which diverts metabolites into PPP [ 6 ]. (degruyter.com)
Precursors2
  • The other bio-route for flavour synthesis is based on de novo microbial processes (fermentation) or on bioconversions of natural precursors using microbial cells or enzymes (biocatalysis). (medcraveonline.com)
  • An attractive alternative method for flavour and fragrance synthesis is based on de novo microbial processes (fermentation) or on bioconversions of natural precursors using microbial cells or enzymes (biocatalysis) [2]. (medcraveonline.com)
Proteins1
  • The stroma also contains the ___,____, and ribosomes involved in the synthesis of several chloroplast proteins. (flashcardmachine.com)
Chemical4
  • Due to the simplicity of their synthesis and the modularity of their stereoelectronic properties, NHCs have unquestionably emerged as one of the most fascinating and well-known species in chemical science. (journaltocs.ac.uk)
  • Their chemical structures are elucidated by the modern sophisticated techniques like mass spectroscopy and NMR that is followed by their chemical synthesis. (medcraveonline.com)
  • The chemical synthesis of fragrances is not desirable as this is not ecofriendly. (medcraveonline.com)
  • Here are a few case studies of collaborative chemical synthesis projects that Endeavour has participated in recently. (endeavourchem.co.uk)
Extraction1
  • Data extraction and synthesis: Two researchers independently extracted data on study characteristics and outcomes and assessed quality. (researchgate.net)
Biological4
  • Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. (benthambooks.com)
  • The development of robust enzymes, in particular cellulases, is a key step in the success of biological routes to `second-generation' biofuels. (jbei.org)
  • Biological cleavage of lignin has been well characterized in fungi, in which enzymes that create free radical intermediates are used to degrade this material. (jbei.org)
  • 2015). Metal oxides, in spite of having many modes of nanoparticle synthesis, are widely accepted in "green synthesis", which means, synthesizing nanoparticles with biological sources from microscopic algae to macroscopic plants. (nanomedicine-rj.com)
Bacterial1
  • Indolyl Septanoside Synthesis for In Vivo Screening of Bacterial Septanoside Hydrolases. (iqs.edu)
Alkaloids1
  • Precursor-directed synthesis of apoptosis-initiating N-hydroxyalkyl phenylbenzoisoquinolindione alkaloids. (mpg.de)
Naturally1
  • Humulene, also known as α-humulene or α-caryophyllene, is a naturally occurring monocyclic sesquiterpene (C15H24), containing an 11-membered ring and consisting of 3 isoprene units containing three nonconjugated C=C double bonds, two of them being triply substituted and one being doubly substituted. (wikipedia.org)
Simplicity1
  • This synthesis is noteworthy for the simplicity of the C−C bond constructions and cyclization steps, which it is believed will prove advantageous in the synthesis of related polyterpenoids. (wikipedia.org)
Metabolism1
  • While it is also an impressive source of B complex vitamins that help in enzyme synthesis, nervous system function and regulating metabolism. (netmeds.com)
Activity3
  • The results presented here demonstrate that this domain leads to a reduced enzyme activity, in addition to its ability to increase long-term solubility of the protein. (journaltocs.ac.uk)
  • The product contains no methyl jasmonate or salicylic acid, instead its main ingredient is potassium (K) which increases enzyme activity making the essential oil production more efficient. (potlovesme.com)
  • Transglycosylation activity of engineered Bifidobacterium lacto- N -biosidase mutants at donor subsites for lacto- N -tetraose synthesis. (iqs.edu)
Functions1
  • Use of metals in nanoparticle synthesis is an advantage since these metals are somewhere or the other linked to the body's functions. (nanomedicine-rj.com)
Stem1
  • Increased Collagen Production: In on study, Gardenia stem cells were shown to upregulate the synthesis of collagen. (alitura.com)
Production2
  • Not just that, it also inhibited the production of the enzyme MMP-1, the enzyme responsible for the decline of collagen within the skin. (alitura.com)
  • Environmental and safety considerations should also be taken into account during the synthesis process to minimize the production of hazardous waste and ensure the safety of the workers. (thebiotek.com)
Natural products1
  • Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. (dattanibookagency.in)
Cancer1
  • Consequently, ROS-modulation has emerged as an anticancer strategy with synthesis of various ROS-inducing or responsive agents that target cancer cells. (degruyter.com)
Formation1
  • The formation of humulene from FPP is catalyzed by sesquiterpene synthesis enzymes. (wikipedia.org)
Design1
  • Deficiency of vitamin A is common in developing countries and was inspiration for the design and synthesis of the genetically-modified golden rice, which is used as a source of vitamin A to help prevent blindness in children. (pressbooks.pub)
Create1
  • Activated acylfulvenes can oxidize various cellular thiols, as well as create DNA adducts that disrupt DNA and RNA synthesis. (biomedcentral.com)
Leads1
  • The subsequent mutagenesis of this plastic residue leads to generation of a mutant enzyme SanSyn F441V which can produce both α - and β -santalenes. (nature.com)