• Serum levels of interferon-g (IFg), tumor necrosis factor alpha (TNFa) and autoantibodies (a-AT) to these cytokines were investigated in patients with Parkinson's disease (PD). (msk.ru)
  • Severe cases of SARS-COV-2 infected patients experience lymphocytopenia and a high activation of metabolic proinflammatory cytokines mechanisms which leads to an elevated blood concentration of interleukin (IL) 2 (IL-2), IL-6, IL-7, interferon gamma (IFN-γ), macrophage inflammatory protein- 1 alpha (MIP1A), and tumor necrosis factor alpha (TNF-α) pro-inflammatory cytokines ( 4 , 13 ). (frontiersin.org)
  • This high level of cytokines, known as cytokine storm syndrome (CSS), tends to be a critical factor of morbidity and mortality for COVID-19 patients. (frontiersin.org)
  • This therapy also led to significant reductions in serum levels of tumor necrosis factor alpha (TNFα) and interleukin 6 (IL-6), two inflammatory cytokines associated with SLE. (nature.com)
  • SSRIs and SNRIs decrease the neuroinflammation through multiple mechanisms including the reduction of blood or tissue cytokines or regulating complex inflammatory pathways: nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), inflammasomes, Toll-like receptor 4 (TLR4), peroxisome proliferator-activated receptor gamma (PPARγ). (springer.com)
  • Inflammatory markers including serum C-reactive protein, cytokines (interleukins 6 and 10), tumor necrosis factor-alpha, and soluble receptors (sTNFR1 and sTNFR2) were assessed with enzyme immunoassay. (nursingcenter.com)
  • It has been hypothesized that inflammatory cytokines are the key factors that underlie RA [ 5 ]. (hindawi.com)
  • Specific binding modules were achieved by performing phage display selections towards the targets Tumor necrosis factor alpha (TNF⍺) and Interleukin-17c (IL-17c), both proinflammatory cytokines involved in many different inflammatory diseases and therefore interesting targets for therapeutic applications. (kth.se)
  • In vitro , wogonoside decreased the production of pro-inflammatory cytokines like Nitric oxide (NO), prostaglandin E2 (PGE 2 ), tumor necrosis factor alpha (TNF-α), and interleukin-6 (IL-6). (oncotarget.com)
  • Proinflammatory cytokines (eg, tumor necrosis factor-alpha, interleukin-1) may be responsible for some changes. (msdmanuals.com)
  • The THP-1 DCs had significantly increased expression of cluster of differentiation 11c (CD11c), CD40, CD80, CD83, and CD86, as well as secretion of tumor necrosis factor-alpha. (hindawi.com)
  • Recent evidence suggests that a physiological function of TTP is to inhibit tumor necrosis factor alpha secretion from macrophages by binding to and destabilizing its mRNA (Carballo, E., Lai, W.S., Blackshear, P.J., 1998. (embl.de)
  • Interpretation of abnormal thyroid function test results in ill patients is complicated by the effects of various drugs, including the iodine-rich contrast agents and amiodarone, which impairs the peripheral conversion of T4 to T3, and by drugs such as dopamine and corticosteroids, which decrease pituitary secretion of TSH, resulting in low serum TSH levels and subsequent decreased T4 secretion. (msdmanuals.com)
  • and (3) types of outcomes - the primary outcome was total efficacy rate, which was ≥ 50% repigmentation rate, and the secondary outcomes were cure rate (proportion of patients achieving 100% repigmentation of the lesion), serum cytokine levels, and blood ratio of CD4 + /CD8 + T cells. (medscape.com)
  • Therefore, the aim of this study was to evaluate the plasma cytokine levels, specifically tumor necrosis factor-α (TNF-α), interleukin (IL)-6, and IL-4, in chronic periodontitis patients and T2DM patients, so as to investigate the influence of chronic periodontitis in systemic inflammation associated with diabetes mellitus. (thejcdp.com)
  • Aderka D, Engelmann H, Maor Y, Brakebusch C, Wallach D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. (aaem.pl)
  • Tumor necrosis factor-alpha -308 promoter gene polymorphism and increased tumor necrosis factor serum bioactivity in farmer's lung patients. (cdc.gov)
  • From this library, it was possible to achieve protein modules with the ability to simultaneously bind to its intended target as well as to human serum albumin (HSA), a feature that has been shown to increase the binder's half-life in the body. (kth.se)
  • Gribova I.E., Gnedenko B.B., Poleshchuk V.V., Morozov S.G. (2003) Content of interferon-gamma, alpha tumor necrosis factor and autoantibodies to them in blood serum during parkinson's disease. (msk.ru)
  • calprotectin, toll-like receptor 4 and nuclear factors-kappa B p65 protein expression in ankle tissues were determined by Western blot analysis. (ijpsonline.com)
  • This latter effect was due to protein kinase C activation in that it was inhibited by sphingosine and was not seen with 4 alpha-PMA, an inactive analogue. (jci.org)
  • But Actos also improved several heart disease risk factors, including cholesterol and markers of inflammation, such as C-reactive protein. (natap.org)
  • Hypersensitive C-Reactive Protein (CRP), tumor necrosis factor-alpha (TNF-α), and angiotensin II (ANG II) were measured using ELISA. (biomedcentral.com)
  • As secondary endpoints, the effects of exercise treatment on patients" cortisol awakening response as well as on brain-derived neurotrophic factor, insulin-like growth factor 1 and inflammatory markers (tumor necrosis factor-alpha, interleukin-6 and C-reactive protein) serum levels will be assessed. (galileo-training.com)
  • Proteins containing CCCH Znf domains include Znf proteins from eukaryotes involved in cell cycle or growth phase-related regulation, e.g. human TIS11B (butyrate response factor 1), a probable regulatory protein involved in regulating the response to growth factors, and the mouse TTP growth factor-inducible nuclear protein, which has the same function. (embl.de)
  • The mouse TTP protein is induced by growth factors. (embl.de)
  • Another protein containing this domain is the human splicing factor U2AF 35kDa subunit, which plays a critical role in both constitutive and enhancer-dependent splicing by mediating essential protein-protein interactions and protein-RNA interactions required for 3' splice site selection. (embl.de)
  • Periodontitis is a chronic infection capable of inducing an inflammatory response that increases the level of proteins during the acute phase, such as C-reactive protein, and considering that these proteins are independent risk factors for cardiovascular diseases, this could explain the connection between periodontal disease and heart disease that is, periodontal diseases increase the risk of cardiovascular diseases. (bvsalud.org)
  • We also collected the water from Chinese water pipes to assess the mutagenicity of its major components and simulated Chinese water-pipe smoke exposure fine particulate 2.5 (PM2.5) by using the High Volume Air Sampler and individuals' sera to search for the potential protein biomarkers of COPD. (who.int)
  • TNF alpha is an inflammatory cytokine expressed by neutrophils, monocytes and macrophages. (journalcra.com)
  • Inflammatory markers such as interleukins 1 and 6 (IL-1, IL-6) and tumor necrosis factor alpha (TNF-a) could help identify early the presence of protracted postoperative ileus. (medscape.com)
  • Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. (researchgate.net)
  • Fever may also be related to necrotic-inflammatory phenomena of the tumor and/or to alterations in liver function and consequent disorders of steroidogenesis. (medscape.com)
  • OBJECTIVES--To test the hypothesis of a diurnal variation in circulating levels of interleukin-6 (IL-6) and/or tumour necrosis factor-alpha (TNF-alpha) in rheumatoid arthritis and other inflammatory connective tissue diseases. (bmj.com)
  • Adalimumab is a recombinant human anti-TNF-alpha IgG1 monoclonal antibody that blocks inflammatory activity of TNF-alpha. (medscape.com)
  • Golimumab is a human anti-TNF-alpha monoclonal antibody that blocks the inflammatory activity of TNF-alpha. (medscape.com)
  • Imani and co-workers stated that OSAS is associated with a variety of inflammatory factors. (bufflo.biz)
  • There is growing evidence that TNF-alpha and its two receptors play an important role in hormonal regulation, metabolism, inflammation and cancer. (aaem.pl)
  • More rarely, the tumor may interfere with normal metabolic pathways or steroid metabolism. (medscape.com)
  • Cachexia is thought to be caused by bioactive molecules produced by the tumor, such as alpha-lymphotoxin (tumor necrosis factor [TNF] alpha), peptides, and nucleotides, which are able to affect metabolism. (medscape.com)
  • This disturbance in bone metabolism could be linked to the main risk factors for HS, such as obesity and smoking. (medpagetoday.com)
  • Commonality of risk factors, changes in systemic in ammatory mediators and body metabolism play a role in this association. (who.int)
  • 14] reported that women with a higher serum cholesterol level had an increased risk of ovarian cancer. (researchsquare.com)
  • We hypothesized that in older PLWH, plasma mtDNA would be associated with lower cognitive performance, frailty, and higher serum IL-6 level. (natap.org)
  • The authors concluded that adult subjects with OSAS had significantly higher serum/plasma TNF levels compared to healthy and age-matched controls. (bufflo.biz)
  • Haider S, Knofler M. Human tumour necrosis factor: physiological and pathological roles in placenta and endometrium. (aaem.pl)
  • Quadros, NP , Roberts-Thomson, P & Gallus, A 1995, ' Sera from patients with systemic lupus erythematosus demonstrate enhanced IgG binding to endothelial cells pretreated with tumour necrosis factor alpha ', Rheumatology International , vol. 15, no. 3, pp. 99-105. (edu.au)
  • Furthermore, cardiovascular comorbidities have been determined as key factors of mortality for SARS-CoV-2 infected patients, which present high blood levels of cardiac-specific proteins troponin I and/or T, indicative signs of hypoxia, tachyarrhythmia, myocarditis, and myocardial injury ( 3 - 8 ). (frontiersin.org)
  • Case studies performed on COVID-19 patients, and autopsies conducted on those who died due to cardiovascular complications such as stroke and acute coronary syndromes, point to thrombotic disease as a critical factor of mortality in severe cases of COVID-19 ( 9 - 12 ). (frontiersin.org)
  • Patients with severe COVID-19 pneumonia progress to ARDS, accompanied by disseminated intravascular coagulation (DIC) ( 17 ), which may upregulate the coagulation pathways by activation of procoagulant factors, such as tissue factor, leading to both arterial and venous thrombotic disease. (frontiersin.org)
  • These biochemical mechanisms are main factors associated with disturbance of blood coagulation in COVID-19 patients. (frontiersin.org)
  • Opala T, Rzymski P, Wilczak M, Woźniak J. Evaluation of soluble tumour necrosis factor alpha receptors p55 and p75 in ovarian cancer patients. (aaem.pl)
  • A positive correlation between leptin and tumor necrosis factor (TNF)-α levels was found in COPD exacerbations, while it disappeared in patients with stable disease. (karger.com)
  • Sera concentration of circulating sCD40L and IL-10 were assayed using ELISA in 30 HCV-positive patients with HCC, 30 HCV-positive patients with liver cirrhosis and 30 age-matched healthy volunteers with negative anti-HCV-Ab as a control group. (who.int)
  • Serum sCD40Lshowed statistically-significant high levels in HCV-HCC patients compared to HCV-cirrhotic patients and normal controls (P (who.int)
  • Serum sCD40L had higher diagnostic value in HCC patients compared with serum AFP. (who.int)
  • Assessment of serum IL-10 levels in HCV patients may provide a possible predictive marker for disease progression. (who.int)
  • Les concentrations sériques de sCD40L circulant et d'interleukine 10 circulante ont été analysées à l'aide de la méthode immuno-enzymatique chez 30 patients positifs pour le VHC avec un CHC, chez 30 patients patients positifs pour le VHC avec une cirrhose du foie, et chez 30 volontaires d'âge correspondant en bonne santé avec des anticorps anti-VHC négatifs servant de groupe témoin. (who.int)
  • With increasing globalization and advancements in modern medicine, novel therapeutic approaches such as targeted molecular therapy [ 4 ], immunotherapy [ 5 ], and latent/residual tumor cell ablation have been used to improve clinical outcomes for cancer patients, but the prognosis for patients with gastric cancer remains poor. (hindawi.com)
  • However, with the development of immunology, western scientists are gradually realizing the importance of homeostasis in the human body, especially immune balance in tumor patients [ 9 ]. (hindawi.com)
  • Autoimmune antiidiotype-like antibody (Ab2) directed against anti-HIV-1gp120 (Ab1) was found in high titer in the sera of 10 consecutive homosexual and 11 narcotic addict HIV-1-related immunologic thrombocytopenia (HIV-1-ITP) patients, was barely detectable in 10 nonthrombocytopenic HIV-1 sero-positive individuals, and was not detectable in 5 normal subjects by use of a solid-phase RIA. (jci.org)
  • METHODS--Serum levels of IL-6 and TNF-alpha were measured at three hour intervals from 7:30 to 22:30 in 48 patients with different rheumatic diseases as well as ten healthy controls. (bmj.com)
  • In four of the patients with rheumatoid arthritis, serum IL-6 levels were measured before and after one week of treatment with prednisolone 15-20 mg daily. (bmj.com)
  • However, serum IL-6 levels were substantially increased in patients with rheumatoid arthritis. (bmj.com)
  • Levels of TNF-alpha were low in patients with rheumatoid arthritis and high in patients with other connective tissue diseases, but without circadian rhythm. (bmj.com)
  • 15] found that oxidized low-density lipoprotein (ox-LDL) in serum was higher in ovarian cancer patients than in control subjects, but total cholesterol (TC) and high-density lipoprotein (HDL) showed no such association. (researchsquare.com)
  • Patients with HS had lower serum 25-hydroxyvitamin D levels and a higher percentage of degraded and partially degraded bone microarchitecture than controls. (medpagetoday.com)
  • Importantly, after adjusting for potential confounders, such as body mass index and tobacco use, total hip BMD and TBS remained significantly lower in patients with HS, suggesting that HS may be an independent risk factor for bone disease. (medpagetoday.com)
  • Moreover, treatment with anti-TNF (tumor necrosis factor)-alpha agents also did not have a significant effect on TBS in patients with HS. (medpagetoday.com)
  • [ 9 ] Serum and salivary TNF levels are elevated in oral lichen planus patients. (medscape.com)
  • Of possible significance, elevated concentrations of interleukin-6 (IL-6) and neopterin in saliva and serum of patients with the erosive-atrophic form of oral lichen planus suggest they may be involved in the etiology of this disease variation. (medscape.com)
  • The study is powered to detect (alpha = .05, beta = .2) a medium effect size difference between the two groups (d = .5) in terms of patients" change in the Children"s Depression Rating Scale raw-score, from baseline until the end of the intervention. (galileo-training.com)
  • An elevated arterial or free venous serum ammonia level is the classic laboratory abnormality reported in patients with hepatic encephalopathy. (medscape.com)
  • Euthyroid sick syndrome is a condition in which serum levels of thyroid hormones are low in patients who have nonthyroidal systemic illness but who are actually euthyroid. (msdmanuals.com)
  • Background: The adipocyte products, leptin and tumour necrosis factor (TNF)alpha are associated with atherosclerotic diseases and may be factors contributing to the enhanced cardiovascular risk in hypopituitary patients with growth hormone (GH) deficiency. (lu.se)
  • Fasting concentrations of leptin, TNF alpha and insulin were analysed in patients and controls. (lu.se)
  • Serum leptin did not differ significantly between patients and controls. (lu.se)
  • However, when serum leptin concentrations were expressed per kilogram fat mass, the patients had significantly greater concentrations (P = 0.01). (lu.se)
  • Serum TNF alpha and TNF alpha per kilogram fat mass were also significantly greater in the patients (both P = 0.001). (lu.se)
  • In the patients, serum leptin concentrations correlated positively with kilogram fat mass (r = 0.54, P = 0.002). (lu.se)
  • The aim of this study was to analyze serum concentrations of p55 and p75 and hormonal status in healthy women during the normal menstrual cycle. (aaem.pl)
  • Serum insulin, adipocytokines and plasminogen activator inhibitor-1 (PAI-1) concentrations were measured using a customized multiplex Luminex assay. (biomedcentral.com)
  • Conclusions: In contrast to serum concentrations of TNF alpha. (lu.se)
  • Statins can improve the chronic inflammation status reflected by the decreasing of serum CRP and hs-CRP levels, whereas there is no conclusive evidence that it can improve the nutrition status. (nih.gov)
  • Olsson I, Gatanaga T, Gullberg U, Lantz M, Granger GA. Tumour necrosis factor (TNF) binding proteins (soluble TNF receptor forms) with possible roles in inflammation and malignancy. (aaem.pl)
  • The factors that cause normally harmless episodes of inflammation to culminate in disease are largely unknown but likely include genetic and environmental influences. (nih.gov)
  • Colon musocal inflammation and damage were assessed by measuring colon mass, morphologic damage score, colonic myeloperoxidase enzyme (MPO) activity, serum TNF-α and colonic TNF-α mRNA level. (wjgnet.com)
  • CONCLUSION: Results from mostly white, highly educated adults supported a mitigating role of metformin in ties between depression, a well-known behavioral risk factor, and inflammation, a key source of biological aging. (bvsalud.org)
  • These cells interact with tumor cells, via common signaling, and induce inflammation and immunosuppression locally in the tumor, but also systemically. (lu.se)
  • AGP is a sensitive acute phase reactant and its concentration can increase by a factor of 3 within 24-48 hours when inflammation occurs. (cdc.gov)
  • The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction. (thejcdp.com)
  • From the final findings, it may be concluded that non-surgical periodontal therapy showed a tendency to reduce the CRP serum levels. (bvsalud.org)
  • Objective: To investigate whether leptin and TNF alpha are increased in a group of hypopituitary women previously found to have increased cardiovascular morbidity, and to compare them with matched individuals of the same sex and age and with similar body composition. (lu.se)
  • serum leptin did not differ from that in controls, implying that leptin is not a major contributor to the previously found increase in cardiovascular morbidity in the hypopituitary women investigated. (lu.se)
  • In a broad sense, these syndromes are collections of symptoms that result from substances produced by the tumor, and they occur remotely from the tumor itself. (medscape.com)
  • In other cases, paraneoplastic syndromes result from the production and release of physiologically active substances by the tumor. (medscape.com)
  • Pyrolysis is closely related to the occurrence and development of many diseases, such as ulcerative colitis, tumors, and cardiovascular diseases [ 7 , 8 ]. (hindawi.com)
  • To investigate the regulatory effect of electroacupuncture (EA) at Zusanli (ST36) on tumor necrosis factor-alpha (TNF-α) in rats with ulcerative colitis (UC), and further elucidate the therapeutic mechanism of EA on UC. (wjgnet.com)
  • Each kit provides sufficient reagents to perform up to 10 preps, and each preparation can purify up to 10 mL of serum or plasma samples with a yield of ~600 μg of LDL/VLDL per mL and ~4500 μg of HDL per mL for human samples (expected yield will vary by species). (antikoerper-online.de)
  • To 10 mL of serum or plasma on ice, add 50 μL of Dextran Solution and 500 μL of Precipitation Solution A. Incubate 5 minutes on ice. (antikoerper-online.de)
  • For the present meta-analysis and meta-regression of serum and plasma tumor necrosis factor-alpha levels in individuals with and without OSAS, these investigators performed a systematic, unrestricted search of PubMed/Medline, Scopus, the Cochrane Library, and the Web of Science Databases Identification of relevant articles published up to February 1st, 2020. (bufflo.biz)
  • Significantly higher levels of TNF in serum but not in plasma have been observed in children with OSAS. (bufflo.biz)
  • Changes in leukocyte count (solid circles), platelet count (solid squares), and serum antibodies tests for Human herpesvirus 6 (HHV-6), Herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) after admission. (cdc.gov)
  • Globally, gastric cancer remains a serious threat to human health given its high morbidity and mortality [ 1 - 3 ], and tumor treatment continues to be an important issue in modern medicine. (hindawi.com)
  • Engelmann H, Holtmann H, Brakebusch C, Avni YS, Sarov I, Nophar Y, Hadas E, Leitner O, Wallach D. Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. (aaem.pl)
  • When a tumor arises, the body may produce antibodies to fight it by binding to and destroying tumor cells. (medscape.com)
  • [ 9 ] For example, antibodies or T cells directed against the tumor may mistakenly attack normal nerve cells. (medscape.com)
  • The method achieved satisfactory performance using the Institute for Reference Materials and Measurements (IRMM) lyophilized human serum reference material ERM-DA470k, which has a certified AGP value of 0.617 g/L as measured by various methods using ERM-D470 as calibrant. (cdc.gov)
  • Endometrial cancer invasion depends on cancer-derived tumor necrosis factor-alpha and stromal derived hepatocyte growth factor. (aaem.pl)
  • Most tumors, including brain tumors in children, contain not only tumor cells, but also various types of immune cells and other stromal cells. (lu.se)
  • Significant positive correlation was detected between serum sCD40L and IL-10(r = 0.85 P (who.int)
  • Immunotherapy has proven effective in experimental brain tumor models and several clinical trials have been initiated. (lu.se)
  • Treatment led to statistically significant reductions in proteinuria and serum creatinine and preserved renal architecture. (nature.com)
  • Results: TNF alpha levels were significantly higher in preeclamptic women compared to normotensive pregnant women (p=0.001). (journalcra.com)
  • Venous blood was withdrawn for obtaining serum samples from the subjects. (thejcdp.com)
  • Angiogenic and lymphangiogenic effect of the drugs assessed pathologically through counting of the newly formed capillaries and lymphatics that immunohistochemically expressed by vascular Endothelial Growth Factor (VEGF), CD34 and D2-40 in liver sections using Cell Image Analyzer and serologically by evaluation of serum level of Tumor Necrosis Factor-Alpha (TNF-α). (degruyter.com)
  • Wogonoside also inhibited hypertrophy and the generation of vascular endothelial growth factor (VEGF) in interleukin-1β (IL-1β)-induced chondrocytes. (oncotarget.com)
  • Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. (springer.com)
  • Acute liver failure (ALF) is a life-threatening clinical syndrome characterized by rapid hepatocellular necrosis due to various acute injuries induced by hepatotoxic drugs, immune-mediated attack, or viral infections. (springer.com)
  • To determine the effect on compartmentalization of the tumor necrosis factor (TNF)-alpha response in the lung and systemically after ventilation with high peak inspiratory pressure with and without positive end-expiratory pressure (PEEP). (nih.gov)
  • The transfer of lymphocytes or ethylene di-isocyanate (HDI), which are used in a serum from sensitized mice can cause clinical disease in naive variety of industries including polyurethane foam mice. (cdc.gov)
  • The host response to this infection is an important factor in determining the extent and severity of the disease. (medscape.com)
  • Avoiding the factors that promote brain immune activation could prevent autism altogether. (coconutresearchcenter.org)
  • Imbalance of the immune system can lead to the development of tumors. (hindawi.com)
  • In addition to the balance between tumors and the immune system, there is also a balance between tumors and the nonimmune cells that surround them [ 10 ]. (hindawi.com)
  • Thus, both the ability of antitumor drugs to kill tumor cells and their effects on immune function and normal tissue cells should be studied. (hindawi.com)
  • Autoimmune anti-HIV-1gp120 antibody with antiidiotype-like activity in sera and immune complexes of HIV-1-related immunologic thrombocytopenia. (jci.org)
  • These agents regulate key factors of the immune system. (medscape.com)
  • Our research is focused on investigating how the immune system can be modulated from tumor-promoting conditions to a state where the immune system instead helps to reject tumors. (lu.se)
  • and AGP can be assessed in residual serum as long as the specimens have been stored frozen at -70C. (cdc.gov)
  • Our results showed significant decrease in serum TNF-α in ART-treated group compared to control infected and PZQ treated groups. (degruyter.com)
  • Hepatorenal syndrome is diagnosed when a creatinine clearance rate of less than 40 mL/min is present or when a serum creatinine level of greater than 1.5 mg/dL, a urine volume of less than 500 mL/day, and a urine sodium level of less than 10 mEq/L are present. (medscape.com)
  • Chegini N. An inverse relation between the expression of tumor necrosis factor alpha (TNF-alpha) and TNF-alpha receptor in human endometrium. (aaem.pl)
  • Although the data in this field are not decisive and there are some confounding factors in human studies, it can be inferred that the use of any illicit drug with an effect on male sexual health reduces fertility potency. (magiran.com)
  • Modifiable risk factors for frailty including neurocognitive impairment, obesity, smoking, choice of initial cART (with NNRTI [non-nucleoside reverse transcriptase inhibitor]-based cART increasing risk of frailty), and level of education. (natap.org)
  • whereas, the serum level of other positive reactants, such as ceruloplasmin and haptoglobin, increases during such reactions. (cdc.gov)
  • Tristetraprolin (TTP), the prototype of a class of CCCH zinc finger proteins, is a phosphoprotein that is rapidly and transiently induced by growth factors and serum in fibroblasts. (embl.de)
  • The causes of hypertrophic osteoarthropathy remain unknown, although several hypotheses have been developed (eg, estrogen or growth hormone [GH] production by the tumor, vagal hyperactivity). (medscape.com)
  • Periodontitis in itself, is a chronic infectious disease of the supporting tissues of the teeth, with multiple related factors [6]. (bvsalud.org)
  • We searched the databases such as EMBASE, PubMed, and Web of Science with the keywords "stem cell," "progenitor cell," "satellite," "senescence" and excluded the keywords "cancer," "tumor," "malignancy" and "carcinoma" until June 2020. (magiran.com)
  • Serum antibody tests for CMV and HSV were negative, but a serum antibody test for EBV was positive (1:640) on day 2 after admission. (cdc.gov)
  • Serum antibody tests for HHV-6 were positive (1:80 on day 7 and 1:280 on day 30 after admission), suggesting that this was a case of HHV-6 reactivation. (cdc.gov)
  • Considerable time and effort has been spent in developing targeted therapies to fight SLE, yet only one therapy, belimumab (Benlysta), a monoclonal antibody targeting B cell-activating factor, or BAFF, has been approved for the treatment of SLE in the last half-century 16 . (nature.com)
  • Serum assessment showed elevated levels of Tumor Necrosis Factor- alpha in both GERD and Barrett's. (cdc.gov)
  • The determination is used in the assessment of the activity of acute and recurring inflammations as well as of tumors with cell necrosis (Schmid, 1975). (cdc.gov)
  • Thus, it is important to search for effective and accessible prognostic factors to identify ovarian cancer. (researchsquare.com)
  • Weight increase and obesity in menopausal females have been identified as the most important prognostic risk factors for breast cancer in postmenopausal women [ 3 ]. (biomedcentral.com)
  • Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin alpha effects. (aaem.pl)
  • After treatment with prednisolone, levels of serum IL-6 decreased significantly, but the circadian rhythm remained. (bmj.com)
  • These models can be used to answer how tumors respond to new cancer treatments, how current treatment works in tune with new treatments, and provide detailed knowledge of specific interactions between the tumor and surrounding cells. (lu.se)
  • A standardized and reproducible protocol for serum-free monolayer culturing of primary paediatric brain tumours to be utilized for therapeutic assays. (lu.se)
  • TNF alpha can be used as a predictive marker for preeclampsia. (journalcra.com)
  • Elevated tumor necrosis factor alpha and interleukin-6 serum levels as marker for complicated Plasmodium falciparum malaria. (ajtmh.org)
  • Onsrud M, Shabana A, Austgulen R, Nustad K. Comparison between soluble tumor necrosis factor receptors and CA125 in peritoneal fluids as a marker for epithelial ovarian cancer. (aaem.pl)