• Signs and symptoms may include bone pain and/or deformity, neurologic disorders, elevated cardiac output and other vascular disorders, and increased serum alkaline phosphatase and/or urinary hydroxyproline levels. (nih.gov)
  • Pamidronate for Injection USP therapy in patients with Paget's disease has been effective in reducing serum alkaline phosphatase and urinary hydroxyproline levels by ≥50% in at least 50% of patients, and by ≥30% in at least 80% of patients. (sdrugs.com)
  • The serum level of hydroxyproline excretion correlates well with its urinary level. (medscape.com)
  • However, given that physiological conditions such as age, gender, and health status, as well as the intake of other foods with highly accessible amino acids or fatty acids may affect plasma acylcarnitine levels and their excretion into urine [64, 65], these metabolites may not be suitable markers per se for specific and quantitative assessment of meat intake and are therefore not considered for further validation as single markers. (musiceye11.com)
  • As a major part of collagen, hydroxyproline has an essential role in collagen stability. (medscape.com)
  • Two isomeric forms of hydroxyproline have been identified in collagenTrans-4-hydroxy-L-proline is found in type I and type III collagen, whereas higher amounts of trans-3-hydroxy-L-proline are found in type IV collagen. (medscape.com)
  • Therefore, without hydroxyproline, no functional collagen fibers appear in the extracellular space. (medscape.com)
  • The ratio of hydroxyproline/creatinine in a fresh specimen of early morning urine, considered the total urinary hydroxyproline, is the best index of collagen breakdown in metastatic bone disease. (medscape.com)
  • Spot urine testing is measurement of choice in screening for bony involvement by malignancy because collagen intake does not influence hydroxyproline/creatinine. (medscape.com)
  • Chapter calcium and hydroxyproline, urine collagen cross links deoxy pyridinoline, serum tartrate-resistant acid phosphatase. (familytreecounseling.com)
  • To determine the effect of thiamine (vitamin B,) on collagen production during wound healing, hydroxyproline content (HP), lysyl oxidase activity (LO), and pepsin-solubilized collagen components were examined in dermis, wound fluid, and artificially induced granulation tissue from surgically wounded rats. (coek.info)
  • In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. (pharmfair.com)
  • Glycine is the primary amino acid in collagen, making up one-third of its amino acids in the repeated form of tripeptides (glycine-proline-Y and glycine-X-hydroxyproline, where X and Y can be any amino acid). (examine.com)
  • In addition, the serum ratios of arginine/citrulline, tyrosine/phenylalanine, and serine/glycine were higher in CG T30 than in RG T180. (bvsalud.org)
  • Etidronate disodium therapy does not adversely affect serum levels of parathyroid hormone or calcium. (nih.gov)
  • Miacalcin injection is indicated for the early treatment of hypercalcemic emergencies, along with other appropriate agents, when a rapid decrease in serum calcium is required, until more specific treatment of the underlying disease can be accomplished. (drugs.com)
  • Serum calcium and phosphate was indeed calculated colorimetrically (BioVision, Milpitas, CA). Solution PTH is dependent on chemical immunoassay for undamaged PTH (ALPCO, Salem, NH). (romeomorales.info)
  • Standard hypercalcemia-related metabolic parameters, such as serum levels of calcium, phosphate, magnesium, and potassium, should be carefully monitored following initiation of therapy with pamidronate disodium. (pfizermedicalinformation.com)
  • In Paget's disease of bone, 17% of patients treated with 90 mg of pamidronate disodium showed serum calcium levels below 8 mg/dL. (pfizermedicalinformation.com)
  • Serum phenylalanine, tryptophan, and hydroxyproline were higher in RG T0 (dogs with CKD before consuming a renal diet) when compared to RG T180. (bvsalud.org)
  • Spot urine assays for N-telopeptide levels have replaced 24-h urine collections for hydroxyproline as a measure of antiresorptive activity. (sagepub.com)
  • Antibodies directed against SVCV react with the homologous virus in serum neutralization, immunofluorescence, immunoperoxidase, or enzyme-linked immunosorbent assays, but they cross-react to various degrees with the pike fry rhabdovirus (PFR), suggesting the 2 viruses are closely related. (musiceye11.com)
  • The object discrimination test was used, with a normal stage (NS) and a reverse stage (RS), and blood samples were collected to evaluate the serum polyunsaturated fatty acid (PUFA) concentration and total antioxidant capacity (TAC) before (T0) and 30 (T1), 60 (T2) and 90 (T3) days after beginning the study. (bvsalud.org)
  • Their plasma of growth not is blood of the Na(+)-K(+)-exchanging ATPase and they are severely involved in spin percutaneous muscles for that urine. (siriuspixels.com)
  • Plasma-EDTA and serum samples were taken after overnight fasting during the fifth week of feeding. (hindawi.com)
  • Plasma, serum, and fecal samples not immediately analyzed were frozen at −80°C. (hindawi.com)
  • This could reflect an increase in urine crystal inhibitory interest due toward highest urinary citrate amount. (romeomorales.info)
  • This observational study aimed to evaluate serum and urinary amino acid (AA) concentrations in healthy dogs and dogs with chronic kidney disease (CKD) fed a commercial therapeutic renal diet with reduced protein and phosphorus levels. (bvsalud.org)
  • The Veterinary two General actions day whether heart being contains greater in patients with ' immune ' survival variability versus a rate function of neuroprotective testing, kidney coursework, failure, and metabolism, and is its urine on rate care numbness, died cardiac contrast, and loss gene. (augenta.net)
  • Here is a case report showing abnormal lab results including baseline serum levels of immunoglobulins and sexual hormones, see the supplementary data e table 1. (poiscenter.com)
  • [ 1 ] However, urinary hydroxyproline better discriminates (x 100) between normal and metastatic disease of the bone. (medscape.com)
  • Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. (pharmfair.com)
  • In urine, the total EAA/total non-essential AA ratio in RG T180 was higher than in CG T30 as well as tyrosine/phenylalanine ratio higher in CG T30. (bvsalud.org)
  • Renal Tubular Defects in Small Animals The form of metabolic acidosis that occurs in acute kidney injury and Stages 2-4 of chronic kidney disease, referred to as uremic acidosis, is due to reduced urine-acidifying ability of diseased. (merckvetmanual.com)
  • Three acylcarnitines (acetylcarnitine, propionylcarnitine and 2-methylbutylcarnitine) were significantly higher in the urine of subjects from the EPIC cohort after the intake of meat and fish compared to control subjects with no meat intake, with no distinction among the different animal protein sources [38]. (musiceye11.com)
  • Serum for bile acid analysis was available at the baseline and at the end of the study (mean treatment duration DOK2 = 2.38 ± 0.56 years) for 56 of these patients. (dehydrogenase-signal.com)
  • The gastric and gallbladder emptying time was reduced after long term acid inhibition by omeprazole in the treatment of reflux esophagitis combined with concomitant reduction of postprandial release of pancreatic polypeptides and normal serum VIP and CCK. (wjgnet.com)
  • [ 9 ] Moreover, hydroxyproline level measurements may permit illness monitoring and assessment of treatment response in such settings. (medscape.com)
  • You can also find here Habibou's blood/urine tests results. (poiscenter.com)
  • Vigorous saline hydration, an integral part of hypercalcemia therapy, should be initiated promptly and an attempt should be made to restore the urine output to about 2 L/day throughout treatment. (sdrugs.com)
  • The serum eicosapentaenoic acid (EPA) + HA concentrations at T1, T2 and T3 were higher than at T0 for the EG (p = 0.0159), in addition, EG showed higher serum EPA + DHA concentrations than CG at T2 (p = 0.0245). (bvsalud.org)
  • The virus is shed mostly with the feces and urine of clinically infected fish and by carriers. (musiceye11.com)
  • It was concluded that the cognitive function of puppies can be enhanced with DHA-concentrated fish oil supplementation without increasing the serum lipid oxidation. (bvsalud.org)
  • This research suggests that subsequent degree should be done into the person Limit stone formers to select the negative effects of K-cit into the urine supersaturation when it comes to Cover and you can stone formation. (romeomorales.info)