• We determined the serum level of antibody to hepatitis B surface antigen (anti-HBsAg) in 273 randomly selected 7-9-year-old schoolchildren from Zanjan City, Islamic Republic of Iran, who had been fully vaccinated against hepatitis B starting at birth. (who.int)
  • The surface antigen, HBsAg is a good marker in the estimation of the number of hepatitis B virus (HBV) carriers among a population because its presence shows either an acute viral hepatitis B or a chronic carriage state of the HBV [ 1 - 3 ]. (omicsonline.org)
  • Here, we aimed to investigate the role of HBV DNA and hepatitis B surface antigen ( HBsAg ) monitoring to predict off- treatment sustained response. (bvsalud.org)
  • Monitoring of HBsAg level can guide the timing of stopping lamivudine in HBeAg -negative chronic hepatitis B . (bvsalud.org)
  • It has been postulated that polymerized human serum albumin may play a role in the infection of hepatocytes by hepatitis B virus, because both the envelope of hepatitis B virus (HBsAg) and hepatocytes exhibit binding activity for human serum albumin after cross‐linking by glutaraldehyde. (mssm.edu)
  • HBsAg particles bound transglutaminase‐cross‐linked as well as glutaralde‐hyde‐cross‐linked human serum albumin as demonstrated by radioimmunoassay and immunoelectron microscopy. (mssm.edu)
  • The binding was blocked by preincubation of HBsAg with transglutaminase‐or glutaraldehyde‐cross‐linked human serum albumin, anti‐HBs or monoclonal anti‐pre‐S2, but not by polymerized bovine or rat serum albumin or by monomeric human serum albumin. (mssm.edu)
  • These data indicate that HBsAg particles contain specific binding sites for transglutaminase‐cross‐linked human serum albumin, but it remains to be determined whether the albumin polymers play a role in the attachment of hepatitis B virus to hepatocytes. (mssm.edu)
  • The Alinity s HBsAg Confirmatory assay is used to confirm the presence of hepatitis B surface antigen (HBsAg) in human serum and plasma by means of specific antibody neutralization on the Alinity s System. (fda.gov)
  • HBV) DNA loss with d detection of antibodies against HBeAG) or - until Hepatitis B surface antigen (HBsAG) seroconversion or - until loss of efficacy (see section 4.4). (who.int)
  • Subjects with suspected liver disease (SLD), defined on the basis of elevated serum alanine aminotransferase (ALT) and gamma-glutamyl-transferase (GGT) activity, hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV)-RNA positivity, were matched with randomly selected subjects of the same age and sex without SLD. (nih.gov)
  • Anti HBc IgM appears shortly after HBV infection and can be detected in serum soon after the appearance of circulating HBsAg and HBeAg. (thyrocare.com)
  • Both subsequently developed HBsAg and acute hepatitis. (karger.com)
  • Serum samples from all study subjects were tested for hepatitis B surface antigen (HBsAg) and antibodies to HCV (anti-HCVs) by enzyme immunoassays, as well as HCV RNA by reverse transcription-PCR assays. (aacrjournals.org)
  • Chromatographic kits were used to detect the presence of HBsAg and antibodies against HCV in serum samples of the studied subjects. (biomedcentral.com)
  • This study aimed to determine the magnitude of serum HBsAg and the risk factors for hepatitis B virus infection among pregnant women in Bahir Dar. (biomedcentral.com)
  • Blood sample was taken from 338 study participants and serum was tested for hepatitis B surface antigen (HBsAg) using Enzyme Linked ImmunoSorbent Assay. (biomedcentral.com)
  • Immunochromatographic Test for Qualitative Detection of Hepatitis B Surface Antigen (HBsAg) in Serum or Plasma. (arkray.co.jp)
  • Routine screening of donor blood for hepatitis B surface antigen (HBsAg) has nearly eliminated the previously common posttransfusion transmission, but transmission through needles shared by drug users remains common. (msdmanuals.com)
  • For example, a hepatitis B surface antigen (HBsAg) level of less than 1 s/c is considered negative, while a level more than 5 s/c is considered positive. (medscape.com)
  • The prevalence of infection for at least 15 years, that antibody hepatitis B carriers varies in different parts levels decrease the most among persons of the world, ranging from less than 1% to immunized at 4 years of age or younger, and 15% [ 2 ]. (who.int)
  • Recommendations have also been developed for the prevention and control of hepatitis C virus (HCV) infection. (cdc.gov)
  • NHANES testing for markers of infection with hepatitis viruses will be used to determine secular trends in infection rates across most age and racial/ethnic groups, and will provide a national picture of the epidemiologic determinants of these infections. (cdc.gov)
  • There is a need for improved immunogenicity of hepatitis B virus (HBV) vaccines among young adults with risk of infection. (nih.gov)
  • Lamivudine is a nucleoside analogue and reverse transcriptase inhibitor used in the therapy of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infection. (nih.gov)
  • Lamivudine is a rare cause of liver test abnormalities or clinically apparent liver injury in patients with HIV infection without hepatitis B. Although several instances of lactic acidosis with hepatic steatosis and liver failure have been reported in patients receiving lamivudine, in all instances other nucleoside analogues more clearly associated with mitochondrial injury [didanosine, stavudine, zalcitrabine, zidovudine] were also being taken. (nih.gov)
  • Mortality and morbidity related to hepatitis C virus infection in hospitalized adults-A propensity score matched analysis. (medscape.com)
  • Therapy should be initiated by a health care provider experienced in the management of HIV infection or treatment of chronic hepatitis B. (who.int)
  • HIV co-infection), the patient should be closely monitored for evidence of exacerbation of hepatitis (see section 4.4). (who.int)
  • The present invention provides a simple and robust human liver cell-based system in which persistent hepatitis C infection, persistent hepatitis B infection or ethanol exposure induces a clinical Prognostic Liver Signature (PLS) high-risk gene signature. (sumobrain.com)
  • This technique is best for "when you have an enriched population of antigen-specific cells-they're not there, except for a short time after vaccination or infection," says Wilson. (the-scientist.com)
  • HCV Rapid Test is used as an aid in the diagnosis of hepatitis C infection. (rapidtest.com)
  • Many people who are infected with the hepatitis C virus do not show the symptoms, thus are not aware of the infection. (rapidtest.com)
  • Serological evidence of HCV infection may be obtained by testing for HCV antigens or antibodies in serum of individuals suspected of hepatitis C infection. (rapidtest.com)
  • The levels are high during acute infection and typically disappear within 6 months, though it can persist in some cases of chronic hepatitis. (thyrocare.com)
  • Hepatitis B Core antigen test is used to detect hepatitis B virus (HBV) infection in an individual. (thyrocare.com)
  • The one-step strip-style HBeAg test is a direct binding rapid test for the visual detection of hepatitis B e antigen (HBeAg) in serum to aid in the diagnosis of hepatitis B infection. (prsbio.com)
  • It has been reported that as many as 80% of HCC cases can be attributed to chronic hepatitis B virus (HBV) infection ( 2 ). (spandidos-publications.com)
  • HBV was originally recognized as the age responsible or serum Repatitis the most common form of partially transmitted viral Repatitis and an import cause of acute and chronic infection of the liver. (researchwap.com)
  • A population-based case-control study was conducted in Taiwan to determine the hepatitis C virus (HCV)-associated risk of hepatocellular carcinoma (HCC) in a hyperendemic area for hepatitis B virus (HBV) infection. (aacrjournals.org)
  • Basuki B. Age, hepatitis B infection and risk of anti hepatitis B surface antigen. (ui.ac.id)
  • Aberrant IgG glycosylation is a feature of hepatitis B virus (HBV) infection but its effect on a long-term efficacy of antiviral therapy has never been addressed. (ncku.edu.tw)
  • The overall prevalence of hepatitis B virus infection among pregnant women were 16 (4.7%) (95% CI 2.7, 7.7). (biomedcentral.com)
  • 95% CI 1.1-10.1) were the significant risk factors for hepatitis B virus infection. (biomedcentral.com)
  • Hepatitis B virus (HBV) is DNA virus causing hepatitis in humans which is classified as chronic hepatitis B and acute hepatitis B virus infection. (biomedcentral.com)
  • The risk of HBV infection transmission decreases where there is periodic perinatal HBV screening, immunoprophylaxis given infants born with HBV infected mother and hepatitis vaccine given both to the high risk mother and the newborn. (biomedcentral.com)
  • Prior unrecognized infection is common but is much less widespread than that with hepatitis A virus. (msdmanuals.com)
  • In the US, 3322 cases of acute hepatitis B infection were reported in 2018-a decrease from the 25,000 annual cases reported before use of hepatitis B vaccine became widespread. (msdmanuals.com)
  • Neonatal Hepatitis B Virus (HBV) Infection Neonatal hepatitis B virus infection is usually acquired during delivery. (msdmanuals.com)
  • Presence of the antigen longer than 6 months after initial exposure indicates chronic infection. (medscape.com)
  • It is used to assess recovery from infection and candidacy for antiviral therapy and to differentiate between inactive carrier state and chronic active hepatitis in chronic HBV infection. (medscape.com)
  • Infection with hepatitis D virus leads to liver disease and cancer most rapidly of all hepatitis viruses. (cdc.gov)
  • A recent Viral Hepatitis Prevention Board meeting reviewed the current epidemiological status, improvements in diagnostic testing, advances in the development of novel antiviral agents in phase III trials and the need for a greater public health response, such as new guidelines and recommended testing of all people newly identified as infected with hepatitis B virus for hepatitis D virus infection. (cdc.gov)
  • In 2016, World Health Organization (WHO) introduced global targets for the care and management of hepatitis C virus (HCV) infection to eliminate hepatitis C as a public health threat by 2030. (cdc.gov)
  • The timing of antiviral therapy cessation in hepatitis B e antigen ( HBeAg )-negative patients is controversial. (bvsalud.org)
  • A total of 53 HBeAg -negative chronic hepatitis B patients who received lamivudine for 34 ±23 (range 12-76) months and had lamivudine stopped for 47 ±35 months were studied. (bvsalud.org)
  • In patients who are positive for hepatitis B e antigen (HBeAg-positive patients) without cirrhosis, treatment should be continued - for at least 6-12 months after confirmed BeAG seroconversion (i.e. (who.int)
  • The One Step HBeAg Test is designed for in vitro diagnostic use in the rapid and qualitative detection of Hepatitis Be antigen directly from serum. (prsbio.com)
  • The HBeAg test One-step is based on the principle of the sandwich immunoassay for the determination of HBeAg in serum. (prsbio.com)
  • Pegasys is indicated for the treatment of hepatitis B envelope antigen (HBeAg)-positive or HBeAg-negative chronic hepatitis B (CHB) in adult patients with compensated liver disease and evidence of viral replication, increased alanine aminotransferase (ALT) and histologically verified liver inflammation and/or fibrosis. (roche.com)
  • It is also indicated for the treatment of HBeAg-positive CHB in non-cirrhotic children and adolescents 3 years of age and older with evidence of viral replication and persistently elevated serum ALT levels. (roche.com)
  • After a screening of 1,085 patients, 132 eligible HBV e antigen (HBeAg)-positive and 101 HBeAg-negative patients with anti-HBV nucleos(t)ide analogue monotherapy were enrolled with on-treatment follow-ups for at least one year. (ncku.edu.tw)
  • The results indicated that a high level of serum fucosyl-agalactosyl IgG1 (IgG1-G0F) at baseline was associated with the severity of liver inflammation and damage but advanced treatment responses, including HBV DNA loss, HBeAg seroconversion, a reduced drug resistance rate, and a liver histological improvement at year 1, thereby improving the long-term treatment efficacy and the probability of treatment discontinuation in HBeAg-positive patients. (ncku.edu.tw)
  • In conclusion, IgG1-G0F favors the medication outcome for HBeAg-positive chronic hepatitis B. (ncku.edu.tw)
  • Loss of HBeAg and appearance of anti-HBe in serum is called seroconversion, which is an important clinical event in the course of HBV disease. (medscape.com)
  • Proposed cutoffs for consideration for antiviral therapy is 100,000 copies/mL or 20,000 IU/mL in HbeAg-positive patients with chronic hepatitis and 10,000 copies/mL or 2,000 IU/mL in HbeAg-negative patients. (medscape.com)
  • In 1993, 495 additional samples from participants with a medical occupation who were negative for antibody to hepatitis core antigen were tested to determine mIU/ml of antibody to assess vaccination status. (cdc.gov)
  • Hepatitis B surface antibody testing was only done on hepatitis B core antibody positives. (cdc.gov)
  • Results of the serum hepatitis B surface antibody can not be used to estimate the vaccination status of the U.S. population since all participants were not tested for this serologic marker. (cdc.gov)
  • For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. (medscape.com)
  • The Ortho HBc ELISA Test System is a qualitative enzyme-linked immunosorbent assay (ELISA) for the detection of total antibody to anti-HBc in human serum or plasma. (cdc.gov)
  • This HCV Rapid Test also known as One Step HCV test is a direct binding assay for the visual detection of hepatitis C antibodies (anti-HCV) in serum. (rapidtest.com)
  • Flow cytometric detection of intracellular antigens has become a standard method in establishing proper leukemic cell lineage affiliation. (ijpmonline.org)
  • Regarding the detection of intracellular antigens, standardization of the procedure remains, however, a real challenge. (ijpmonline.org)
  • Detection of intracellular antigens by flow cytometry (FCM) requires effective fixation and permeabilization of the cell membrane. (ijpmonline.org)
  • Nineteen national-level public health laboratories performed routine dengue diagnostic assays on a proficiency testing panel consisting of two modules: one containing commercial serum samples spiked with cultured dengue viruses for the detection of nucleic acid and non-structural protein 1 (NS1) (Module A) and one containing human serum samples for the detection of anti-dengue virus antibodies (Module B). A review of logistics arrangements was also conducted. (who.int)
  • All nine laboratories performing NS1 antigen detection obtained the correct results. (who.int)
  • Hepatitis B virus (HBV) testing plays an important role in detection, classification, and management of HBV disease . (medscape.com)
  • [ 4 ] Detection of anti-HBs in the serum implies either active or passive immunization that usually persists for life. (medscape.com)
  • To achieve these results, Georgia implemented HCV core antigen (HCVcAg) testing, utilization of point-of-care HCV RNA, and simplification of HCV viremia detection by qualitative HCV RNA. (cdc.gov)
  • HA516 trade name] is indicated for the treatment of chronic hepatitis B in adults with: · compensated liver disease and evidence of immune active disease, i.e. active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence of active inflammation and/or fibrosis. (who.int)
  • Recently, a study that investigated a cohort of 117 men showed that raising serum testosterone concentrations to normal levels by treatment with parenteral testosterone for 1 year improved the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), as well as weight, body mass index (BMI), waist size, and lipid profiles [ 26 ]. (biomedcentral.com)
  • Background: In Togo, no overall prevalence of hepatitis B has been previously estimated and yet it is a country located in an area of high transmission of this virus. (omicsonline.org)
  • The objective of this study was to document the prevalence of HBs antigen among youth aged 15 to 24 in Togo in 2010 and its associated factors. (omicsonline.org)
  • It covers a serum bank samples of 2,101 obtained in the framework of a national survey on the prevalence of HIV/AIDS among subjects of both sexes aged 15 to 24 years. (omicsonline.org)
  • The prevalence of viral hepatitis B among patients in National Orthopedic Hospital Enugu was studied. (researchwap.com)
  • Hepatitis-B surface antigen and antibody: prevalence and persistence in institutionalized and noninstitutionalized persons. (cdc.gov)
  • The Journal of Viral Hepatitis is a bimonthly journal, publishing reviews, original work (full papers) and short rapid communications in the area of viral hepatitis. (medscape.com)
  • Guinea pig liver transglutaminase covalently cross‐linked human serum albumin molecules into dimers, trimers and polymers up to hexamers as shown by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. (mssm.edu)
  • An exacerbation of hepatitis also typically occurs after development of lamivudine resistance, a few weeks or months after the initial appearance of the mutant HBV strain and rise in HBV DNA levels (Case 2). (nih.gov)
  • Hepatitis viruses constitute a major public health problem because of the morbidity and mortality associated with the acute and chronic consequences of these infections. (cdc.gov)
  • In addition, NHANES provides the means to better define the epidemiology of other hepatitis viruses. (cdc.gov)
  • Incidentally, not all "hepatitis" is caused by viruses. (researchwap.com)
  • Five hepatotropic viruses (A to E) are known to cause hepatitis. (biomedcentral.com)
  • Overview of Acute Viral Hepatitis Acute viral hepatitis is diffuse liver inflammation caused by specific hepatotropic viruses that have diverse modes of transmission and epidemiologies. (msdmanuals.com)
  • Presence of HBcAg (core Antigen) in the cytoplasm and nucleus may reflect disease activity and predict response to antiviral treatment. (thyrocare.com)
  • Medical charts were retrospectively evaluated for clinical and serological data and frozen sera were tested for the presence of antibodies against HIV, hepatitis C virus, and thyroid antigens. (vitality101.com)
  • Treatment flares typically occur during the first few months of therapy and are marked by asymptomatic elevations in serum aminotransferase levels and rarely with jaundice or symptoms (Case 1). (nih.gov)
  • Severe adverse events occur largely when it is withdrawn in patients with chronic hepatitis B or with the development of antiviral resistance. (nih.gov)
  • Elevations in serum ALT levels occur in a proportion of patients with chronic hepatitis B treated with lamivudine. (nih.gov)
  • In 1991, the World at least 6-8 years before with 3 doses of Health Organization (WHO) recommended hepatitis B vaccine starting at birth to that hepatitis B vaccination be included provide information on the effect of the in national immunization programmes in immunization strategy for hepatitis B and countries with a hepatitis B surface antigen the need for booster doses. (who.int)
  • It has been reported that when hepatitis services is good throughout the territory, B vaccination is initiated at birth, there and vaccinations are delivered through local is an increased likelihood that the child health districts which are able to reach the will complete the series [ 8,9 ] hence an whole population. (who.int)
  • The hepatitis B virus (HBV) vaccination schedule in Libya follows international recommendations (1st dose at birth, 2nd after 1 month and 3rd after 6 months). (hud.ac.uk)
  • Madour, A, Alkout, A & Vanin, S 2013, ' Première évaluation de la concentration sérique de l'antigène de surface du virus de l'hépatite b après la vaccination en Libye ', Eastern Mediterranean Health Journal , vol. 19, no. 12, pp. 990-994. (hud.ac.uk)
  • Ethiopia is now identifying the magnitude of the problem and implementing the vaccination for health workers but still there is no accessibility and availability of vaccination of hepatitis B virus for those healthy mothers. (biomedcentral.com)
  • Vaccination is protective and postexposure use of hepatitis B immune globulin may prevent or attenuate clinical disease. (msdmanuals.com)
  • HA516 trade name] is indicated for the treatment of chronic hepatitis B in adolescents 12 to 18 years of age and weighing at least 35 kg with: · compensated liver disease and evidence of immune active disease, i.e. active viral replication, persistently elevated serum ALT levels and histological evidence of active inflammation and/or fibrosis. (who.int)
  • Hepatitis C is a major cause of liver inflammation, liver disease, and liver cancer in North America. (rapidtest.com)
  • Hepatitis is the inflammation of liver, most commonly caused by viral infections. (biomedcentral.com)
  • The expression of serum miR‑101 in patients with HBV‑related HCC was significantly higher than that in the healthy controls, and this increase correlated with hepatitis B surface antigen positivity, HBV DNA levels and tumor size. (spandidos-publications.com)
  • This study was undertaken to determine the seroprevalence of HBsAgs and anti-HCV antibodies and what socio-demographic factors are associated with sero-positivity of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections among pregnant women attending maternity ward of Felege Hiwot Referral Hospital, northwest, Ethiopia. (biomedcentral.com)
  • To demonstrate manufacturing equivalence of a 3-antigen (3A) HBV vaccine, evaluate noninferiority of seroprotection rate (SPR) of 3A-HBV vs single-antigen (1A) HBV after 2 and 3 vaccine doses, and compare safety and reactogenicity between 3A-HBV and 1A-HBV vaccines. (nih.gov)
  • More recently, Wilson and others have devised ways to isolate single, antigen-specific B cells from the blood of human donors with active immune responses against a particular pathogen or vaccine. (the-scientist.com)
  • The study also gave the general view of the group of individual affected whether children or adult, and the wid expired of the repetitious B. Hepatitis B one of the major cause of human suffering in the world despite a though understanding of its transmission and prevention and control by use of vaccine was found to be prevalent in National Orthopedic Hospital Enugu among the patients. (researchwap.com)
  • Three of the children had antibodies to hepatitis B core protein. (who.int)
  • The patient was subjected to immunological tests (i.e., purified protein derivative, venereal disease research laboratory, anti-human immunodeficiency virus 1/2, anti-hepatitis B surface antigen, anti-hepatitis B core, anti-Epstein-Barr virus, Chagas [ELISA]) and was diagnosed nonreactive. (jcadonline.com)
  • Hepatitis A Hepatitis A is caused by an enterically transmitted RNA virus that, in older children and adults, causes typical symptoms of viral hepatitis, including anorexia, malaise, and jaundice. (msdmanuals.com)
  • The disease is characterized with acute and chronic form and more than 50% of the infected individuals develop severe, life threatening chronic hepatitis with liver cirrhosis and hepatocellular carcinomas. (rapidtest.com)
  • Hepatitis B virus (HBV) is a common cause of acute and chronic viral hepatitis worldwide. (biomedcentral.com)
  • The International Immunodiagnostics HDV Ab assay is a competitive enzyme immunoassay (ELISA) for the determination of antibodies to Hepatitis D Virus or HDV in human plasma and sera with a 'two step" methodology. (cdc.gov)
  • The assay is also intended for use in testing serum and plasma specimens to screen organ donors when specimens are obtained while the donor's heart is still beating, and in testing serum specimens to screen cadaveric (non-heart-beating) donors. (fda.gov)
  • However, the current assay requires plasma or serum. (pasteur.fr)
  • Viral hepatitis during pregnancy is associated with high risk of maternal, fetal and neonatal complications. (biomedcentral.com)
  • There is a high rate of vertical transmission of HBV causing fetal and neonatal hepatitis, which may lead to impaired mental and physical health later in life [ 7 ]. (biomedcentral.com)
  • A case that meets the clinical case definition, is laboratory confirmed, and is not known to have chronic hepatitis B. (cdc.gov)
  • ANTI-HCV InstaTest is based on the principle of double antigen sandwich immunoassay for determination of anti-HCV in serum. (rapidtest.com)
  • Combination of analysis of fluorescence labeling and light scatter properties of cells allows rapid and better determination of target cell antigens. (ijpmonline.org)
  • Serum levels of hepatitis B surface antigen were determined in 277 randomly selected children aged 1-12 years. (hud.ac.uk)
  • Lamivudine is currently used in many HAART regimens but is now rarely used to treat hepatitis B because of a high rate of antiviral resistance when it is used as monotherapy as well as the availability of more potent agents with a higher barrier to resistance. (nih.gov)
  • These elevations appear to be due to a transient flare in the underlying chronic hepatitis B and occur in three situations during and after therapy: upon initiation of therapy (treatment flares), upon development of antiviral resistance (breakthrough flares), and shortly after stopping therapy (withdrawal flares). (nih.gov)
  • The HBs antigen screening was made by the 4th generation, 'sandwich' type of ELISA test. (omicsonline.org)
  • 5. That a Hepatitis B surface antigen test not be performed if the person requesting the test indicates that the test is for a prenatal assessment. (ontario.ca)
  • The test is designed to be used as an aid in the diagnosis of hepatitis B virus infections. (prsbio.com)
  • It would be extremely laborious to use this strategy to try to identify an antibody against an antigen of interest using the blood of a person without an active immune response, he says, because millions of memory B cells are present in the blood, each of which is uniquely specific for a different antigen. (the-scientist.com)
  • Cry1Ac toxin administration induced a strong immune response in serum but in the small intestinal fluids only anti-Cry1Ac IgA antibodies were detected. (scielo.br)
  • In this review, we discuss the use of pVNPs for the delivery of peptide antigens to the host immune in pre-clinical studies with the final aim of promoting systemic immunity against the corresponding pathogens. (eurekaselect.com)
  • However, the relationship between hepatic steatosis and serum testosterone levels has not been extensively studied. (biomedcentral.com)
  • Efficacy and safety of pan-genotypic sofosbuvir and velpatasvir in patients with hepatitis C and HIV coinfection on dolutegravir-based antiretroviral therapy. (medscape.com)
  • Occasionally, coinfection with hepatitis D occurs. (msdmanuals.com)