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  • commonly
  • There are eight serologically distinct botulinum neurotoxin isoforms serotypes A-H. Currently, botulinum neurotoxin serotype A BoNT⁄A is commonly used for the treatment of many disorders, such as hyperactive musculoskeletal disorders, dystonia, and pain. (duhnnae.com)
  • problematic
  • We illustrate how stable, synthetic oligosaccharide analogs of labile CPS induce a specific protective immune response against native CPS using S. pneumoniae serotype 5 (ST-5), a problematic CPS component of Prevnar13. (nih.gov)
  • infection
  • To have complete protection against the dengue infection, a vaccine has to simultaneously stimulate an equally strong antibody response against all four serotypes. (eurekalert.org)
  • Assoc. Prof. Lok's overall strategy is to develop a safe therapeutic by combining four antibodies that inhibit infection of each of the dengue virus serotypes. (eurekalert.org)
  • research
  • Associate Professor Shee-Mei Lok and Research Fellow Guntur Fibriansah, from the Duke-NUS Emerging Infectious Diseases (EID) Programme, led research that showed how an antibody neutralises dengue virus serotype 2 (DENV-2). (eurekalert.org)
  • In past research, Assoc. Prof. Lok has shown that the DENV-2 is more complex than the rest of the dengue serotypes as the mosquito-derived virus has a highly dynamic structure which changes its form, or morphology, as it infects humans. (eurekalert.org)
  • shown
  • An isogenic mutant of S. suis serotype 2 unable to produce Lsp was constructed and shown to process lipoproteins incorrectly, including an S. suis homologue of the pneumococcal PsaA lipoprotein. (sigmaaldrich.com)
  • work
  • Discovering this strain really represents the intellectual detective work that Marie Bugarel did, in that she identified that something just didn't make sense and pursued it to the point that we have confirmation of a new serotype from the reference center at the Pasteur Institute in France," he said. (avma.org)
  • found
  • The serotype is named after the city where it was found, the home of Texas Tech's main campus. (avma.org)