• Taiwan (online Technical Appendix), dis serogroup W135 were reported All isolates were susceptible to 12 an- but no direct epidemiologic links in China during 2006-2008. (cdc.gov)
  • Nucleotide sequencing was used to characterize unidentified California (CAL) serogroup virus isolates from Russia. (ajtmh.org)
  • This study aimed to identify serogroups of Escherichia coli important for human health in isolates from psittacine of illegal wildlife trade in Ceará State. (scielo.br)
  • Within L. monocytogenes , sequences homologous to gtcA were found in all serogroup 4 isolates but not in strains of any other serotypes. (asm.org)
  • Another study in Korea demonstrated that some serogroup 6 isolates encode distinctive cps (capsular) loci, differing from those of most other serogroup 6 isolates. (biomedcentral.com)
  • In the present study, we report the STs of all the serogroup 6 isolates and an association between the STs and antibiotic resistance. (biomedcentral.com)
  • To evaluate the genetic diversity of Legionella pneumophila in Southeast Michigan, we determined the sequence type (ST) and serogroup (SG) of the 18 residential isolates from Flint and Detroit, MI, and the 33 clinical isolates submitted by hospitals in three area counties in 2013 to 2016. (wayne.edu)
  • The Direct Fluorescent Antibody Reagents are intended for the presumptive (serological) identification of Legionella pneumophila serogroups 2 through 14 from culture isolates. (pro-lab.com)
  • Isolates were sent to the National Microbiology Laboratory for confirmation of serogroup and further studies including phenotype and clonal complex identification. (canada.ca)
  • Prior to 2015, most invasive serogroup W isolates were identified as clonal complex 22 (ST-22 CC) and the increase in serogroup W in Canada in recent years has been associated with the replacement of the endemic ST-22 CC with the hyper-virulent ST-11 CC. (canada.ca)
  • Antimicrobial characterisation of CEM-101 activity against respiratory tract pathogens, including multidrug-resistant pneumococcal serogroup 19A isolates. (jmilabs.com)
  • Genome-Based Characterization of Emergent Invasive Neisseria meningitidis Serogroup Y Isolates in Sweden from 1995 to 2012. (ox.ac.uk)
  • Whole-genome sequencing was performed on invasive serogroup Y isolates from 1995 to 2012 in Sweden (n = 186). (ox.ac.uk)
  • These isolates were compared to a collection of serogroup Y isolates from England, Wales, and Northern Ireland from 2010 to 2012 (n = 143), which had relatively low serogroup Y incidence, and two isolates obtained in 1999 in the United States, where serogroup Y remains one of the major causes of IMD. (ox.ac.uk)
  • Serogroup W135, chocolate agar grew N. meningitidis diseases caused by W135 meningo- after 24 h. (cdc.gov)
  • Because of the lack of scribe these 3 meningitis patients and ed therapeutic and prophylaxis agents W135 strains from Hajj pilgrimages the N . meningitidis serogroup W135 used frequently in China. (cdc.gov)
  • On October 29, 2014, a new vaccine against invasive meningococcal disease caused by Neisseria meningitidis serogroup B was licensed by the Food and Drug Administration. (chop.edu)
  • CusabioAlternative Name(s): /Gene Names: ihfBResearch Areas: TranscriptionOrganism: Neisseria meningitidis serogroup B (strain MC58)AA. (joplink.net)
  • CusabioAlternative Name(s): Class 3 protein PorinGene Names: porBResearch Areas: Signal TransductionOrganism: Neisseria meningitidis serogroup BAA. (joplink.net)
  • Serogroup A Neisseria meningitidis was the major cause of meningococcal meningitis epidemics in the African meningitis belt before 2010 when the monovalent meningococcal A conjugate vaccine (MenAfriVac) was introduced in the region. (springer.com)
  • Therefore, this study aimed to establish the trends in N. meningitidis serogroups from 2016 to 2020 in Ghana's meningitis belt. (springer.com)
  • This study showed the emergence of serogroup X, a non-vaccine type, as the predominant N. meningitidis serogroup in the wake of a declining serogroup W in Ghana's meningitis belt. (springer.com)
  • SynF is a capsule biosynthesis gene that uniquely identifies Neisseria meningitidis serogroup Y from the other meningococcal serogroups. (loinc.org)
  • https://www.cdc.gov/meningitis/lab-manual/chpt10-pcr.html] There has been a large increase in the proportion of meningococcal disease caused by N. meningitidis serogroup Y since 1989. (loinc.org)
  • Recent vaccines for serogroups A and C have proven to be more effective in that age group which has led to serogroup Y being the most likely cause of pneumonia from Neisseria meningitidis. (loinc.org)
  • IMD is caused by Neisseria meningitidis, with the majority of cases caused by serogroups (A, B, C, W, Y) in most of the world. (gsk.com)
  • Menveo does not prevent N eisseria meningitidis serogroup B infections. (gsk.com)
  • BACKGROUND: In a previous study 60 infants receiving an nvestigational a serogroup B meningococcal vaccine containing recombinant meningococcal proteins alone (rMenB) or combined with an outer-membrane vesicle from Neisseria meningitidis (4CMenB) at 6, 8 and 12 months of age produced serum bactericidal antibodies (SBA) against meningococcal strains expressing vaccine antigens. (ox.ac.uk)
  • Neisseria meningitidis serogroups A, B, C, W, X and Y are responsible for most of these life -threatening infections , and its unpredictable epidemiology can cause outbreaks in communities , with significant health , social and economic impact. (bvsalud.org)
  • Two novel protein -based vaccines are a significant addition to our armamentarium against N. meningitidis as they provide broad coverage against highly diverse strains in serogroup B and other groups. (bvsalud.org)
  • ; Neisseria meningitidis serogroup W ( NmW ) and Hemophilus influenzae type b ( Hib ). (who.int)
  • We measured antibodies against Neisseria meningitidis serogroups A, C, Y and W135 in mothers and their 2-month-old infants at study enrollment. (ox.ac.uk)
  • Draft Genome Sequence of a Neisseria meningitidis Serogroup C Isolate of Sequence Type 11 Linked to an Outbreak among Men Who Have Sex with Men. (pasteur.fr)
  • Invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup Y has increased in Europe, especially in Scandinavia. (ox.ac.uk)
  • FDA has approved the first combination vaccination for use in children aged 6 weeks through 18 months for the prevention of invasive disease caused by Neisseria meningitidis serogroups C and Y and Haemophilus influenza type b, according to an FDA statement. (formularywatch.com)
  • These vaccines may also be given to anyone 16 through 23 years old to provide short-term protection against most strains of serogroup B meningococcal disease, based on discussions between the patient and health care provider. (cdc.gov)
  • Previously, meningococcal vaccines licensed for use in the U.S. only covered four of the five main serogroups of bacteria that cause meningococcal disease: A, C, W and Y. (chop.edu)
  • While all adolescents are currently recommended to receive the current meningococcal vaccines (either Menactra® or Menveo®), the new serogroup B vaccine, Trumenba®, offers an opportunity to protect against the type of meningococcal infection that was recently diagnosed on the campuses of Princeton University and University of California, Santa Barbara. (chop.edu)
  • Global epidemiology of serogroup B meningococcal disease and opportunities for prevention with novel recombinant protein vaccines. (bvsalud.org)
  • Mass vaccination strategies using polysaccharide vaccines have been deployed since the 1970s and the use of conjugate vaccines has controlled endemic and epidemic disease caused by serogroups A, C, W and Y and more recently serogroup B using geographically-specific outer membrane vesicle based vaccines . (bvsalud.org)
  • These novel serogroup B vaccines should be actively considered for individuals at increased risk of disease and to control serogroup B outbreaks occurring in institutions or specific regions, as they are likely to save lives and prevent severe sequelae. (bvsalud.org)
  • A variety of routine childhood and adolescent meningococcal vaccination programs using monovalent (serogroup C) and quadrivalent (A, C, Y, W) conjugate vaccines have been implemented in Canada since 2002, resulting in a decrease in invasive meningococcal disease (IMD) incidence, particularly in serogroup C. Meningococcal vaccines have also been used for outbreak response, including the multicomponent vaccine serogroup B vaccine. (canada.ca)
  • Serogroup W associated with ST-11 CC is becoming a growing contributor of disease in all age groups not protected by serogroup W-containing vaccines. (canada.ca)
  • Since the early 2000s, a variety of routine childhood and adolescent vaccination programs using monovalent (serogroup C) and quadravalent (serogroup A, C, Y and W-135) meningococcal conjugate vaccines have been implemented in Canada Footnote 3 . (canada.ca)
  • Impact of meningococcal serogroup C conjugate vaccines on carriage and herd immunity. (ox.ac.uk)
  • BACKGROUND: In 1999, meningococcal serogroup C conjugate (MCC) vaccines were introduced in the United Kingdom for those under 19 years of age. (ox.ac.uk)
  • Molecular epidemiology of meningococcal disease in England and Wales 1975-1995, before the introduction of serogroup C conjugate vaccines. (ox.ac.uk)
  • This scheme was employed to survey 323 meningococci isolated from invasive disease in England and Wales from 1975 to 1995, before the introduction of meningococcal conjugated serogroup C polysaccharide vaccines in 1999. (ox.ac.uk)
  • BACKGROUND: The meningococcal serogroup C conjugate (MCC) vaccination program has successfully reduced morbidity and mortality from serogroup C disease in England and Wales, owing to high short-term vaccine effectiveness and substantial herd immunity. (bris.ac.uk)
  • Clonal expansion of sequence type (ST-)5 and emergence of ST-7 in serogroup A meningococci, Africa. (cdc.gov)
  • The objective of this study was to investigate the serogroup Y emergence by whole-genome sequencing and compare the meningococcal population structure of Swedish invasive serogroup Y strains to those of other countries with different IMD incidence. (ox.ac.uk)
  • ABSTRACT In this study, the serogroup and susceptibility patterns of Shigella and Salmonella spp. (who.int)
  • O antigen clusters from two serogroup O58 S. enterica strains had approximately 85 % identity with the E. coli O123 O antigen region over their entire length, suggesting that these Salmonella and E. coli O antigen regions evolved from a common ancestor. (microbiologyresearch.org)
  • The O antigen cluster of a Salmonella serogroup O41 isolate had a lower level of identity with E. coli O123 over only part of its O antigen DNA cluster sequence, suggesting a different and more complex evolution of this gene cluster than those in the O58 strains. (microbiologyresearch.org)
  • Results from a head-to-head Phase 3 study, evaluating the immune response of MenQuadfi ® to serogroup C, one of the main serogroups of invasive meningococcal disease (IMD), compared to Nimenrix ® (quadrivalent ACWY vaccine) and NeisVac-C ® (monovalent C vaccine) in healthy toddlers, were presented today in an oral session at the 2021 European Congress of Clinical Microbiology and Infectious Disease. (sanofi.com)
  • Although several serotypes of L. monocytogenes are present in the environment and in foods, the majority of infections are caused by strains of serogroup 1/2 (mostly serotypes 1/2a and 1/2b) and 4 (almost always serotype 4b) ( 6 , 35 ). (asm.org)
  • TA of strains of serogroup 1/2 and 3 consists of polyribitol phosphate, with N -acetylglucosamine (Glc-NAc) and rhamnose (in the case of serogroup 1/2) substituents on ribitol (Fig. 1 ). (asm.org)
  • The predominant clinical presentation of the W135 serogroup was a sepsis in 67% of cases. (uandes.cl)
  • We found that the predominant serovar and serogroup was S . Derby and O:4(B), with a prevalence of 41.9 and 55%, respectively. (frontiersin.org)
  • outbreak because they were genotypi- public of China, all meningococcal An isolate from the cousin of patient cally distinct from the Hajj-related diseases were caused by serogroups 3 was also identifi ed as W135. (cdc.gov)
  • Results: Mothers had low IgG antibodies against serogroups C, W135 and Y polysaccharides, but high serogroup A antibody, whereas 61-78% had protective human complement serum bactericidal activity (hSBA) (≥1:4) for serogroups C, W135 and Y but only 31% for serogroup A. Only 9%, 32%, 45% and 19% of 2-month-old infants had hSBA ≥1:4 for serogroups A, C, W135 and Y, respectively. (ox.ac.uk)
  • At the end of 2011, the W135 serogroup belonging to the hypervirulent clone ST-11 emerged. (uandes.cl)
  • These viruses were isolated from mosquitoes and humans during epidemiologic investigations on the role of CAL serogroup viruses in the increased incidence of arboviral encephalitis in Russia. (ajtmh.org)
  • 1 Recent trends in Europe suggest a decreasing incidence of IMD cases caused by serogroup B and an increase in serogroups Y and W. 1 There has also been a significant increase in the incidence of IMD caused by hypervirulent serogroup W, with a case fatality rate more than twice that of IMD caused by other serogroups. (sanofi.com)
  • The highest age-adjusted incidence rate was associated with serogroup B (0.17 cases per 100, 000 population per year, 95% CI: 0.16-0.19). (canada.ca)
  • This has resulted in a decrease in IMD incidence, particularly for serogroup C. In the last decade, the multicomponent meningococcal B vaccine (4CMenB) has been used to control outbreaks Footnote 3 but has not been used in routine vaccination programs across the country. (canada.ca)
  • In Sweden, serogroup Y is now the dominating serogroup, and in 2012, the serogroup Y disease incidence was 0.46/100,000 population. (ox.ac.uk)
  • A potential cause of this shift is the fact that the polysaccharide capsule based vaccine formulated for serogroups A, C, W-135 and Y is ineffective against children under 2 years of age and has only been useful for outbreaks of the disease. (loinc.org)
  • In the absence of a vaccine that immunizes against the serogroup B capsular polysaccharide, this can only be achieved by targeting subcapsular antigens, and a number of outer-membrane proteins (OMPs) are under consideration as candidates. (ox.ac.uk)
  • Action: As part of the outbreak response, a community-wide meningococcal vaccination programme against serogroups A, C, W and Y was implemented in a collaboration among different agencies of the South Australia Department for Health and Well-being, Aboriginal health and community services providers, and other local service providers and government agencies. (who.int)
  • No local cases of serogroup W occurred during the vaccination programme, but two further cases were notified by the end of 2018. (who.int)
  • Serogroup 6 is one of the most common causes of invasive pneumococcal disease in unvaccinated populations. (biomedcentral.com)
  • 0.5 mu g/ml) stratified by both pneumococcal serogroup and age of the carrier were compared. (diva-portal.org)
  • The results highlight the importance of taking both serogroup and age of the carriers into account when studying the dynamics of pneumococcal transmission in young children. (diva-portal.org)
  • Invasive meningococcal disease caused by some serogroups is vaccine preventable and endemic in Canada, with increased activity occurring periodically in the winter months. (canada.ca)
  • The most common vaccine-preventable serogroups are C and Y. No vaccine is currently available in the United States to protect against serogroup B. (formularywatch.com)
  • The results support division of KEM-related viruses into 3 new serogroups - KEM (comprising KEM and GI subgroups), CNU and WM - and indicate that a 38 to 43kD polypeptide carries the major inter-group specific antigen. (ox.ac.uk)
  • Resolution of a Protracted Serogroup B Meningococcal Outbreak with Whole-Genome Sequencing Shows Interspecies Genetic Transfer. (ox.ac.uk)
  • One hundred four serogroup A meningococci in our collection, isolated in Africa from 1988 to 1999, were characterized by multilocus sequence typing (MLST). (cdc.gov)
  • The impact of this intervention on asymptomatic carriage of meningococci was investigated to establish whether serogroup replacement or protection by herd immunity occurred. (ox.ac.uk)
  • To assess the frequency of serogroups and serotypes, as well as the antimicrobial susceptibility pattern of Shigella species isolated from known cases of diarrhoea and dysentery from Karachi, Pakistan. (aku.edu)
  • Molecular characterization of California serogroup viruses isolated in Russia. (ajtmh.org)
  • About 70% of non-O157 STEC isolated from humans fall into six serogroups, which are (in order of frequency): O26, O103, O111, O121, O45, and O145. (cdc.gov)
  • 50 other STEC serogroups isolated from ill persons, most are probably human pathogens. (cdc.gov)
  • Some STEC serogroups isolated from animals are almost never isolated from ill persons. (cdc.gov)
  • Table 2 presents the results from analysis of raw ground beef component samples for both E. coli O157:H7 and for the non-O157 STECs by each non-O157 STEC serogroup. (usda.gov)
  • Currently, serogroup B is the main cause of MD in Europe and North America and one of the most prevalent serogroups in Latin America . (bvsalud.org)
  • Serogroup 6 traditionally comprises two serotypes, 6A and 6B. (biomedcentral.com)
  • We set out to identify any new serotypes (serotypes "6E", "6F", and "6G") in serogroup 6 S. pneumoniae in China and to report the population biology of this group. (biomedcentral.com)
  • Frequency of isolation of shigella serogroups/serotypes and their anti" by Afia Zafar, Nasim Sabir et al. (aku.edu)
  • A number of serotypes were isolated in each serogroup, 8 serotypes in S. flexneri, 8 serotypes in S. dysenteriae, 9 serotypes in S. boydii, and Phase 1& 2 were found in S. sonnei. (aku.edu)
  • We previously showed that a strain type belonging to sequence type 23 was responsible for the increased prevalence of this serogroup in Sweden. (ox.ac.uk)
  • Problem: From December 2016 to February 2017, two cases of invasive meningococcal disease and one case of meningococcal conjunctivitis, all serogroup W, occurred in Aboriginal children in the Ceduna region of South Australia. (who.int)
  • Serogroup A meningococcus is implicated in a significant number of epidemics of meningitis that occur in the African meningitis belt and China but rarely in industrialised countries. (springer.com)
  • The beginning of the end for serogroup B meningococcus? (ox.ac.uk)
  • Conclusions: The levels of serogroup-specific meningococcal antibodies were low in mothers and 2-month-old infants. (ox.ac.uk)
  • In conclusion, the investigated psittacine from illegal wildlife trade hosted ESBL-producing E. coli strains and some belong to important serogroups often linked to severe human infections. (scielo.br)
  • The disease produced was similar to that observed for strains of L. pneumophila and a representative graph of infection with the Corby strain is shown (A). L. longbeachae serogroup 1 strain A5H5 (B), K4A1, K8B9, A5E1, D-880, and D-493 clustered in this group. (bioz.com)
  • However, serogroup W also causes endemic diseases in some African meningitis belt countries. (springer.com)
  • Serogroup A epidemics in Africa's meningitis belt occur every 8-12 years, with each wave following a gradual increase in volume-decrease in the volume of cases pattern [ 14 ]. (springer.com)
  • A booster dose of MenACWY is recommended at age 16 years, and using shared clinical decision-making, adolescents and young adults aged 16-23 years may also receive serogroup B meningococcal vaccine (MenB). (medscape.com)
  • Meningococcal B vaccine can help protect against meningococcal disease caused by serogroup B. A different meningococcal vaccine is available that can help protect against serogroups A, C, W, and Y. (cdc.gov)
  • Bivalent rLP2086 is a recombinant factor H binding protein-based vaccine approved in the USA for prevention of meningococcal serogroup B disease in 10-25-year-olds. (nih.gov)
  • The proportion of serogroup Y disease increased in the early to mid 1990s. (cdc.gov)
  • Serogroup B continues to account for the greatest proportion of disease. (canada.ca)
  • Future genome-wide association studies are needed to reveal additional genes associated with serogroup Y meningococcal disease, and this work would benefit from a complete serogroup Y meningococcal reference genome. (ox.ac.uk)
  • While serogroup distribution may vary from year to year, serogroups B, C, and Y cause most cases of meningococcal disease in the United States. (formularywatch.com)
  • The high impact on the carriage of ST-11 complex serogroup C could be attributed to high levels of capsule expression. (ox.ac.uk)
  • Immunogenicity was determined in serum bactericidal antibody assay using human complement (hSBA) by use of four meningococcal serogroup B test strains expressing vaccine-heterologous factor H binding protein variants: PMB80 (A22), PMB2001 (A56), PMB2948 (B24), and PMB2707 (B44). (nih.gov)
  • The Phase 3 study met all primary and secondary endpoints, demonstrating that MenQuadfi induced superior immune responses to serogroup C based on geometric mean antibody titers (GMTs*) compared to NeisVac-C - a standard-of-care vaccine - in healthy toddlers. (sanofi.com)
  • The study shows that a switch from monovalent C to MenQuadfi in toddlers can be achieved without compromising serogroup C protection. (sanofi.com)
  • MEQ00065 is a head-to-head comparative, multi-center, Phase 3 study conducted in Germany, Finland and Denmark to compare the immune response against meningococcal serogroup C and describe the safety following a single dose of MenQuadfi in healthy meningococcal vaccine-naïve toddlers 12 to 23 months of age compared to Nimenrix or NeisVac-C. (sanofi.com)
  • No salient antibiotic-resistant clones were isolated among the serogroup 6 S. pneumoniae . (biomedcentral.com)
  • The means and 95% confidence intervals (CIs) were estimated by fitting a gamma distribution to the observed duration of carriage for each age and serogroup stratum. (diva-portal.org)
  • For patients aged 5 years or older, no significant difference in carriage duration for different ages or serogroups could be noted. (diva-portal.org)
  • RESULTS: A reduction in serogroup C carriage (rate ratio, 0.19) was observed that lasted at least 2 years with no evidence of serogroup replacement. (ox.ac.uk)