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AcetyltransferasesSerineHistone AcetyltransferasesCholine O-AcetyltransferaseChloramphenicol O-AcetyltransferaseAcetylationp300-CBP Transcription FactorsSerine O-AcetyltransferaseCarnitine O-AcetyltransferaseMolecular Sequence DataSerine EndopeptidasesN-Terminal Acetyltransferase AN-Terminal Acetyltransferase EBase SequenceDihydrolipoyllysine-Residue AcetyltransferaseAmino Acid SequencePromoter Regions, GeneticSerine ProteasesTranscription, GeneticEscherichia coli O157Acetyl Coenzyme ASerine Proteinase InhibitorsHistonesTransfectionPlasmidsCloning, MolecularCell LineSaccharomyces cerevisiae ProteinsCREB-Binding ProteinBinding SitesGene Expression RegulationTranscription FactorsE1A-Associated p300 ProteinO(6)-Methylguanine-DNA MethyltransferaseMutationNuclear ProteinsPhosphorylationPyruvate Dehydrogenase ComplexN-Terminal AcetyltransferasesN-Terminal Acetyltransferase BProtein BindingSubstrate SpecificityRNA, MessengerSpermineDNA-Binding ProteinsKineticsRecombinant ProteinsSequence Homology, Amino AcidCoenzyme ATranscriptional ActivationVesicular Acetylcholine Transport ProteinsRecombinant Fusion ProteinsCysteine SynthaseLysineRegulatory Sequences, Nucleic AcidTrans-ActivatorsPolyaminesCholinergic FibersSpermidineGene Expression Regulation, EnzymologicRestriction MappingEscherichia coliHeLa CellsMutagenesis, Site-DirectedProtein Structure, TertiarySerine C-PalmitoyltransferaseSaccharomyces cerevisiaeAcetyl-CoA C-AcetyltransferaseChromatinDNACells, CulturedEnhancer Elements, GeneticGenes, ReporterProtein-Serine-Threonine KinasesAcetylcholinesteraseTumor Cells, CulturedAcyltransferasesChloramphenicol ResistanceAnacardic AcidsDNA PrimersGlucosamine 6-Phosphate N-AcetyltransferaseSequence AlignmentCell NucleusGene ExpressionPhosphoserineGenes, RegulatorElectrophoresis, Polyacrylamide GelGenesGenes, BacterialProtein KinasesModels, MolecularCell Cycle ProteinsHistone DeacetylasesChloramphenicolGlycine HydroxymethyltransferasePlatelet Activating FactorThreonineBacterial ProteinsEnzyme ActivationAmino-Acid N-Acetyltransferase

Acetyl-CoAHistoneRegulation of serineSpecific serineLyaseCysteineProteinBiosynthesis1.16GeneHelicaseEnzymeIncludeSpecifically1.30Arylamine N-acetyltransferaThreonine protein kinaseTransacetylaseResiduesArylalkylamine N-acetyltransferaseProteaseACETYL-COAAmino AcidsSERATBacterialPurificationActivityExpression

Acetyl-CoA7

• In enzymology, a serine O-acetyltransferase (EC 2.3.1.30) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L-serine ⇌ {\displaystyle \rightleftharpoons } CoA + O-acetyl-L-serine Thus, the two substrates of this enzyme are acetyl-CoA and L-serine, whereas its two products are CoA and O-acetyl-L-serine. (wikipedia.org)
• The systematic name of this enzyme class is acetyl-CoA:L-serine O-acetyltransferase. (wikipedia.org)
• More specifically, its role is to catalyse the activation of L-serine by acetyl-CoA.This entry refers to the N-terminus of the protein which has a sequence that is conserved in plants and bacteria. (wikipedia.org)
• Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine. (cathdb.info)
• In Acetyl-CoA fermentation to Butyrate its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)
• In Archaeal lipids its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)
• In Serine-glyoxylate cycle its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)

Histone4

• Here we show through systematic epigenetic studies that the histone acetyltransferase p300/CBP-associated factor (PCAF) promotes acetylation of histone 3 Lys 9 at the promoters of established key regeneration-associated genes following a peripheral but not a central axonal injury. (nature.com)
• They also showed that p53-interacting SET inhibits action of histone acetyltransferases (CBP/p300) and lowers p21 expression (Figure 1A). (oatext.com)
• Post-translational modifications (PTMs) of histones include the acetylation of specific lysine residues by histone acetyltransferases (HATs), deacetylation by histone deacetylase (HDACs), the methylation of lysine and arginine residues by histone methytransferases (HMTs), the demethylation of lysine residues by histone demethylases (HDMTs), and the phosphorylation of specific serine groups by histone kinases (HKs). (gentaur.be)
• Euchromatin is also characterized by a high level of histone acetylation, which is mediated by histone acetyltransferases. (gentaur.be)

Regulation of serine1

• 2) Lysine acetylation in histones and various other proteins is certainly effected with the active interplay of acetyltransferase (HAT) and deacetylase (HDAC) enzymes, which is certainly analogous towards the regulation of serine, threonine, and tyrosine phosphorylation by kinases and phosphatases. (smartrailexpo-europe.com)

Specific serine1

• and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. (nih.gov)

Lyase2

• Expression Profile of the Serine Acetyltransferase (SERAT) and O-Acetylserine (thiol)lyase (OASTL) Gene Families in Arabidopsis. (mpg.de)
• We found that one gene cluster - consisting of a cysteine synthase, a cystathionine lyase, and a serine acetyltransferase - is present in all strains that grow in medium with methionine as sole sulfur source. (pacb.com)

Cysteine2

• In molecular biology, the protein domain SATase is short for Serine acetyltransferase and refers to an enzyme that catalyses the conversion of L-serine to L-cysteine in E. coli. (wikipedia.org)
• This particular enzyme catalyses serine into cysteine which is eventually converted to the essential amino acid methionine. (wikipedia.org)

Protein2

• The N-terminal domain of the protein Serine acetyltransferase helps catalyse acetyl transfer. (wikipedia.org)
• Ten of sixteen variants previously associated with iron traits generalized to HCHS/SOL, including variants at the transferrin (TF), hemochromatosis (HFE), fatty acid desaturase 2 (FADS2)/myelin regulatory factor (MYRF), transmembrane protease, serine 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), ABO blood group (ABO), and GRB2 associated binding protein 3 (GAB3) loci. (escholarship.org)

Biosynthesis5

• In plants, association of O-acetylserine sulfhydrylase (OASS) and Ser acetyltransferase (SAT) into the Cys synthase complex plays a regulatory role in sulfur assimilation and Cys biosynthesis. (rcsb.org)
• Wulfert S. and Krueger S.* (2018) Phosphoserine Aminotransferase1 is part of the phosphorylated pathways for serine biosynthesis and essential for light and sugar-dependent growth promotion. (uni-koeln.de)
• Gerlich S.C., Walker B.J., Krueger S., Kopriva S. (2018) Sulfate metabolism in C4 flaveria species is controlled by the root and connected to serine biosynthesis. (uni-koeln.de)
• R. (2017) Studying the function of the phosphorylated pathway of serine biosynthesis in Arabidopsis thaliana . (uni-koeln.de)
• Serine in plants: biosynthesis, metabolism, and functions. (uni-koeln.de)

1.161

• In Serine-glyoxylate cycle its role is 3-ketoacyl-CoA thiolase (EC 2.3.1.16) . (theseed.org)

Gene1

• However, the SbCIccr was integrated into the serine acetyltransferase gene rimL, not into the canonical integration site for SCCs, methyltransferase gene rlmH (orfX). (muni.cz)

Helicase1

• Serine 970 of RNA helicase MOV10 is phosphorylated and controls unfolding activity and fate of mRNAs targeted for AGO2-mediated silencing. (cdc.gov)

Enzyme1

• Of particular interest to scientists, is the ability to harness the natural ability of the enzyme, Serine acetyltransferase, to create nutritionally essential amino acids and to exploit this ability through transgenic plants. (wikipedia.org)

Include1

• Other names in common use include SATase, L-serine acetyltransferase, serine acetyltransferase, and serine transacetylase. (wikipedia.org)

Specifically1

• Using mass spectrometry, we show that MOV10 is phosphorylated in cells at the C-terminus, specifically at serine 970 (S970). (cdc.gov)

1.301

• In enzymology, a serine O-acetyltransferase (EC 2.3.1.30) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L-serine ⇌ {\displaystyle \rightleftharpoons } CoA + O-acetyl-L-serine Thus, the two substrates of this enzyme are acetyl-CoA and L-serine, whereas its two products are CoA and O-acetyl-L-serine. (wikipedia.org)

Arylamine N-acetyltransfera1

• This enzyme is also referred to as serotonin acetylase despite the fact that serotonin acetylation can also occur through the action of broad specificity acetyltransferases such as ARYLAMINE N-ACETYLTRANSFERASE. (wakehealth.edu)

Threonine protein kinase1

• In this study, we show that the Gα subunit PsGPA1 directly interacts with PsYPK1, a serine/threonine protein kinase that consists of an N-terminal region with unknown function and a C-terminal region with a conserved catalytic kinase domain. (prolekarniky.cz)

Transacetylase1

• Other names in common use include SATase, L-serine acetyltransferase, serine acetyltransferase, and serine transacetylase. (wikipedia.org)

Residues4

• Two elements regulate the complex: an E1 kinase and a phospho-E1 phosphatase, which phosphorylate and dephosphorylate, respectively, three serine residues in the E1 α subunit, resulting in the deactivation and activation, respectively, of the complex (2) . (nature.com)
• The acetylation N- and C-terminal histone lysine tail residues, along with lysine methylation and serine/threonine phosphorylation, are important forms of post-translational modification that help couple histones to changes in chromatin organization and allow for the epigenetic control of gene expression. (cellsignal.com)
• We show that YopJ acted as an acetyltransferase, using acetylcoenzyme A (CoA) to modify the critical serine and threonine residues in the activation loop of MAPKK6 and thereby blocking phosphorylation. (elsevierpure.com)
• Transcriptional induction is accompanied by phosphorylation of Pol II at serine (S) residues in the heptapeptide repeats within its C-terminal domain (CTD). (frontiersin.org)

Arylalkylamine N-acetyltransferase4

• Arylalkylamine N-acetyltransferase (AANAT) is the key regulatory enzyme controlling the daily rhythm of melatonin biosynthesis. (nih.gov)
• Arylalkylamine N-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
• This graph shows the total number of publications written about "Arylalkylamine N-Acetyltransferase" by people in this website by year, and whether "Arylalkylamine N-Acetyltransferase" was a major or minor topic of these publications. (wakehealth.edu)
• Below are the most recent publications written about "Arylalkylamine N-Acetyltransferase" by people in Profiles. (wakehealth.edu)

Protease1

• Encodes AtSBT1.1, a subtilisin-like serine protease. (or.jp)

ACETYL-COA6

• The systematic name of this enzyme class is acetyl-CoA:L-serine O-acetyltransferase. (wikipedia.org)
• An enzyme that catalyzes the conversion of L-SERINE to COENZYME A and O-acetyl-L-serine, using ACETYL-COA as a donor. (nih.gov)
• The mode of recognition of acetyl-lysine by the Bromo domain is similar to that of acetyl-CoA by histone acetyltransferases, though the bromodomain is the only domain known that interacts with acetylated lysine containing peptides. (cellsignal.com)
• In Acetyl-CoA fermentation to Butyrate its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)
• In Archaeal lipids its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)
• In Serine-glyoxylate cycle its role is Acetyl-CoA acetyltransferase (EC 2.3.1.9) . (theseed.org)

Amino Acids1

• Of particular interest to scientists, is the ability to harness the natural ability of the enzyme, Serine acetyltransferase, to create nutritionally essential amino acids and to exploit this ability through transgenic plants. (wikipedia.org)

SERAT1

• Expression Profile of the Serine Acetyltransferase (SERAT) and O-Acetylserine (thiol)lyase (OASTL) Gene Families in Arabidopsis. (mpg.de)

Bacterial2

• 2. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. (nih.gov)
• 6. The polysialic acid-specific O-acetyltransferase OatC from Neisseria meningitidis serogroup C evolved apart from other bacterial sialate O-acetyltransferases. (nih.gov)

Purification1

• 10. Properties and partial purification of sialate-O-acetyltransferase from bovine submandibular glands. (nih.gov)

Activity1

• 11. High level of sialate-O-acetyltransferase activity in lymphoblasts of childhood acute lymphoblastic leukaemia (ALL): enzyme characterization and correlation with disease status. (nih.gov)

Expression2

• 12. Induction of sialic acid 9-O-acetylation by diverse gene products: implications for the expression cloning of sialic acid O-acetyltransferases. (nih.gov)
• KEY POINTS: â ¢ Expression of the feedback-insensitive serine O-acetyltransferase provided B. subtilis the ability of accumulating SeCys. (bvsalud.org)