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  • HSAN1
  • The study objective is to evaluate the efficacy of L-serine in subjects with hereditary sensory neuropathy type 1 (HSAN1). (clinicaltrials.gov)
  • In this randomized, double-blind, placebo-controlled cross over study the investigators will enroll 20 research participants with HSAN1 with 10 subjects assigned to L-serine (400mg/kg/d) and 10 assigned to placebo who are each treated for 12 months. (clinicaltrials.gov)
  • production
  • Serine is critical for the production of the body's proteins, enzymes and muscle tissue. (drugbank.ca)
  • Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. (uzh.ch)