Cysteine DioxygenaseCysteineSulfur CompoundsTaurineDioxygenasesCarboxy-LyasesSulfatesGlutathionePyruvate KinaseSerinePyruvate Dehydrogenase ComplexCysteine EndopeptidasesPyruvic AcidCysteine ProteasesPyruvatesPyruvate DecarboxylaseAmino Acid SequenceMolecular Sequence DataCysteine Proteinase InhibitorsCysteine SynthasePyruvate OxidaseSerine EndopeptidasesEnergy MetabolismPyruvate Dehydrogenase (Lipoamide)KineticsOxidation-ReductionLipid MetabolismDisulfidesGlucoseMutagenesis, Site-DirectedSulfhydryl CompoundsLiverSerine Proteinase InhibitorsSerine ProteasesBinding SitesBase SequenceMutationLactatesSequence Homology, Amino AcidEscherichia coliRecombinant ProteinsPyruvate Dehydrogenase (Lipoamide)-PhosphataseGlycolysisCystineLactic AcidCathepsinsSubstrate SpecificityCloning, MolecularModels, MolecularSerine O-AcetyltransferaseCitric Acid CycleProtein ConformationProtein BindingProtein Structure, TertiaryMetabolismCystatinsHydrogen-Ion ConcentrationCarbon IsotopesAlanineChromatography, High Pressure LiquidPhosphorylationAmino AcidsCell LineSulfhydryl ReagentsPapainPhosphoenolpyruvateSulfurCathepsin LAcetatesSequence AlignmentStructure-Activity RelationshipAmino Acid SubstitutionAdenosine TriphosphateBacterial ProteinsElectrophoresis, Polyacrylamide GelMalatesCathepsin BMagnetic Resonance SpectroscopyEthylmaleimideCatalysisCarbon-Sulfur LyasesMitochondriaEnzyme ActivationThiamine PyrophosphateCells, CulturedDichloroacetic AcidModels, BiologicalPyruvate Dehydrogenase Complex Deficiency DiseaseDithiothreitolMethionineMass SpectrometryNADOxygen ConsumptionOxaloacetic AcidIsoenzymesDihydrolipoyllysine-Residue AcetyltransferaseTime FactorsCatalytic DomainProtein Processing, Post-TranslationalRNA, Messenger