acetyl derivatives of aniline of the Amido-benzene series, whose base? (nih.gov)
In this study, a series of novel shikonin N-benzyl matrinic acid ester derivatives (PMMB-299-PMMB-310) were synthesized and tested for their ability to inhibit the proliferation of cancer cells. (bvsalud.org)
6. Novel hydroxamate and anilide derivatives as potent histone deacetylase inhibitors: synthesis and antiproliferative evaluation. (nih.gov)
Alkyne Coupling Pd/C Cancer Anti-proliferation abstract A series of 3-(hetero)aryl substituted 3-[(prop-2-ynyloxy)(thiophen-2-yl)methyl]pyridine derivatives were designed as potential anticancer agents. (dokumen.tips)
Chapter 1 concerns general considerations for separation of metronidazole and tinidazole carbamol and for anilide derivatives. (kurashi-kyoiku.com)
Amides1
The amides formed from aniline are sometimes called "anilides", for example CH 3 -CO-NH-C 6 H 5 is acetanilide . (wikidoc.org)
Inhibitors6
Two series of (hetero)arylamino-naphthoquinones and benzo-fused carbazolequinones were considered for study with the rationale that related structural motifs are present in numerous drugs, clinical trial agents, natural products and hTopoIIα inhibitors. (bvsalud.org)
2. Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors. (nih.gov)
3. 2-aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors. (nih.gov)
13. Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. (nih.gov)
16. Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors. (nih.gov)
A series of benzyloxy anilides of nipecotic (5, 6) and isonipecotic (7, 8) acids were synthesized and assayed in vitro as inhibitors of ADP-induced platelet aggregation and the blood coagulation enzymes factor Xa (FXa) and thrombin (FIIa). (uniba.it)
Compounds3
Procedures for the determination of phenolic products, and the effects of metyrapone (54364) and related compounds on anilide hydroxylation were investigated. (cdc.gov)
The investigated series compounds showed important properties like significant apoptotic antiproliferation in cancer cells with cell cycle arrest at S-phase and downregulation of NF- κß signaling cascade, relatively less cytotoxicity to normal cells, and hTopoIIα inhibition with more efficiency compared to an anticancer drug etoposide. (bvsalud.org)
The SAR-analysis of the substituted arylamides of 4-(4-oxo-4H-quinazolin-3-yl)-piperidine-1-carboxylic acids has demonstrated that the presence of the electron-donating substituents in position 8 of the quinazolin-4-one cycle and in position 4 of the aromatic fragment of the urea increases the activity of the compounds of this series against gram-positive bacteria. (edu.ua)
Case series4
Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series. (nih.gov)
Retrospective interventional case series. (nih.gov)
To report a case series of three patients with hepatitis C virus infection who all presented with severe type B lactic acidosis shortly after starting treatment with ombitasvir-paritaprevir-ritonavir-dasabuvir. (nih.gov)