We find that lung squamous cell carcinoma tumors from AAs exhibit higher genomic instability-the proportion of non-diploid genome-aggressive molecular features such as chromothripsis and higher homologous recombination deficiency (HRD). (nature.com)
Compounds7
In organic chemistry, a homologous series is a sequence of compounds with the same functional group and similar chemical properties in which the members of the series can be branched or unbranched, or differ by molecular formula of CH2 and molecular mass of 14u. (wikipedia.org)
Compounds within a homologous series typically have a fixed set of functional groups that gives them similar chemical and physical properties. (wikipedia.org)
The name "homologous series" is also often used for any collection of compounds that have similar structures or include the same functional group, such as the general alkanes (straight and branched), the alkenes (olefins), the carbohydrates, etc. (wikipedia.org)
Atomic and electronic structures of R 2 O 3 (ZnO) 3 (R=Al, Ga, and In), which are included in homologous series of compounds, are investigated using first-principles calculations based on density functional theory. (elsevierpure.com)
and a Ph.D. from the University of Texas at Austin, where she synthesized a series of strained organic compounds and studied electron transfer in solutions and thin films. (mtsu.edu)
We designed a series of tetrazolium-based compounds for the intracellular release of metal-binding formazan ligands. (bvsalud.org)
Alcohols4
For example, the series of primary straight-chained alcohols has a hydroxyl at the end of the carbon chain. (wikipedia.org)
Some important classes of organic molecules are derivatives of alkanes, such as the primary alcohols, aldehydes, and (mono)carboxylic acids form analogous series to the alkanes. (wikipedia.org)
The corresponding homologous series of primary straight-chained alcohols comprises methanol (CH4O), ethanol (C2H6O), 1-propanol (C3H8O), 1-butanol, and so on. (wikipedia.org)
The long chain linear aliphatic alcohol Category has at its centre an homologous series of increasing carbon chain length alcohols. (europa.eu)
Booster4
vaccine dose and 2 alternative booster dose strategies: 1) a CDC recommends that all persons aged 18 years receive a homologous booster (i.e., 2 Janssen doses) and 2) a heter- single COVID-19 vaccine booster dose 2 months after receipt ologous mRNA booster (i.e., 1 Janssen dose/1 mRNA dose). (cdc.gov)
a heterologous COVID-19 with VE of a homologous booster following mRNA primary mRNA vaccine is preferred over a homologous (matching) series vaccination (i.e., 3 mRNA doses). (cdc.gov)
Using a retrospective cohort study design emulating a target trial, we determined the relative vaccine effectiveness (RVE) of a homologous booster dose of a SARS-CoV-2 messenger RNA (mRNA) vaccine compared with the primary vaccine series alone in preventing infection, hospitalization, and intensive care unit admission, and death in the Department of Veterans Affairs healthcare system in the United States. (nih.gov)
We observed wide geographic variation in primary series vaccination and booster rates, with marked inequities by ZIP code-level education, median household income, essential worker share, and racial/ethnic composition. (cdc.gov)
Vaccination4
Twentyman, and I'm here to discuss recommendations for the Novavax COVID-19 vaccine as a two-dose primary series vaccination against COVID-19 for adults ages 18 years and older. (cdc.gov)
Today we'll be starting with why another primary series vaccine is relevant to COVID-19 vaccination in the US, including a review of adults still in need of their first COVID-19 vaccine dose. (cdc.gov)
Let's start with why another primary series vaccine is relevant in the US by reviewing together the remaining need for primary series COVID-19 vaccination among us adults. (cdc.gov)
SAGE recommended that moderately and severely immunocompromised persons should be offered an additional dose of al WHO EUL COVID-19 vaccines as part of an extended primary series since these individuals are less likely to respond adequately to vaccination fol owing a standard primary vaccine series and are at high risk of severe COVID-19 disease. (who.int)
Heterologous1
VE of other homologous and heterologous three dose series was similar. (cdc.gov)
Alkanes2
The homologous series of straight-chained alkanes begins methane (CH4), ethane (C2H6), propane (C3H8), butane (C4H10), and pentane (C5H12). (wikipedia.org)
Homologous and Analogous Structures: What's the Difference? (prepscholar.com)
The key to understanding these differences lies in knowing what homologous and analogous structures are. (prepscholar.com)
What's the Difference Between Homologous and Analogous Structures? (prepscholar.com)
Homologous and analogous structures have several key differences. (prepscholar.com)
Molecular2
These properties typically change gradually along the series, and the changes can often be explained by mere differences in molecular size and mass. (wikipedia.org)
According to the combination, homologous series and bioisoterism principles of pharmaceutical molecular devise, we designed and. (fip.org)
Genes1
The prevalence of germline HRD (that is, the total number of pathogenic variants in homologous recombination genes) is higher in tumors from AAs, suggesting that the somatic differences observed have genetic ancestry origins. (nature.com)
Dose2
24% after 1 Janssen dose, 54% after 2 Janssen doses, 79% after with homologous boosting ( 2 ). (cdc.gov)
an additional dose of COVID-19 vaccine given after protection from the initial vaccine series begins to decline. (harvard.edu)
Structural1
Herein, we achieve the synthesis and structural study of a luminescent Na-stabilized Ga-Ti oxide homologous series by atomically resolved electron microscopy. (rsc.org)
Complementary1
Single strand annealing proteins (SSAPs) like RedĪ² initiate homologous recombination by annealing complementary DNA strands. (nature.com)
Similarities1
Disagreements about the probable homologous or homoplastic nature of shared derived similarities between taxa lie at the core of most conflicting phylogenetic hypotheses. (creation.com)
Form3
The single-ring cycloalkanes form another such series, starting with cyclopropane. (wikipedia.org)
Biopolymers also form homologous series, for example the polymers of glucose such as cellulose oligomers starting with cellobiose, or the series of amylose oligomers starting with maltose, which are sometimes called maltooligomers. (wikipedia.org)
Titanium, vanadium, and molybdenum oxides all form homologous series (e.g. (wikipedia.org)
Study2
The proposed method yielded prediction errors lower than reported in the literature in all the homologous series that were included in this study. (tau.ac.il)
The study on a homologous series of ethers by Vermue (1993) indicated increasing toxicity with decreasing alkyl chain length. (europa.eu)
Boiling point1
Within that series, many physical properties such as boiling point gradually change with increasing mass. (wikipedia.org)
Primary series2
Recommendations for the Novavax COVID-19 Vaccine Primary Series in Adults 18 Years and Older. (cdc.gov)
In age-stratified analyses, primary series vaccine coverage was very high among the elderly. (cdc.gov)
Similar2
Also, they share a similar protein architecture based on an N-terminal ssDNA binding domain of ~180 amino acids and a C-terminal extension that in the case of RAD52 is required for homologous recombination (HR) through specific protein-protein interactions 6 . (nature.com)
Homologous structures are similar structures in related organisms. (prepscholar.com)
Processes1
In addition to non-homologous end joining, we detect signatures of replication-associated processes and templated insertions. (lu.se)
Properties2
On the periodic table, homologous elements share many electrochemical properties and appear in the same group (column) of the table. (wikipedia.org)
17. We call homologous substances those that have the same chemical properties and whose composition offers certain analogies in the relative proportion of elements. (wikipedia.org)
Blog post1
Found this blog post on the Homologous Series: Cycloalkanes useful? (twinklsecondary.blog)
Linear2
Prediction of normal melting temperature (T m ) using linear Quantitative Structure Property Relationships (QSPR) whose applicability domain is limited to a particular homologous series is considered. (tau.ac.il)
Hn+2PnO3n+1, where n=2-8, and a homologous series of linear and cyclic P6-P16 polyphosphates (Spanggord et al. (cdc.gov)
Rings1
We show that areas in the outer rings of the neocortex have comparable laminar elaboration in rats and primates, while most 6-layer eulaminate areas in the innermost rings of primate neocortex lack homologous counterparts in rats. (springer.com)
Formation1
We show that C-terminally truncated RedĪ², whilst still able to promote annealing and nucleoprotein filament formation, is unable to mediate homologous recombination. (nature.com)
Share2
The most important thing to remember about homologous structures is that they share common ancestry. (prepscholar.com)
Bats and bees do not share common ancestry, so the structures cannot be homologous. (prepscholar.com)
Virus1
The homologous (Lone Star virus) immune ascitic fluid neutralized more than 5 dex of virus. (cdc.gov)
Common1
Common structures that can't be explained by common ancestry are called homoplasies , and are common in the alleged transitional series. (creation.com)
Patients2
[ 9 ] There is a predilection for female patients (in published series, the female-to-male ratio is approximately 2:1) and for African American patients. (medscape.com)
It was first described in 1954 by David Bloom in a series of patients with telangiectatic erythema on the face and dwarfism. (medscape.com)
Members1
In that series, successive members differ in mass by an extra methylene bridge (-CH2- unit) inserted in the chain. (wikipedia.org)