• These tests are also referred to as molecular or genetic assays. (wikipedia.org)
  • We aimed to develop a sensor technology that can quantitatively measure nAb responses against different isolates of SARS-CoV-2, be adapted for an all-in-solution multiwell format and provide rapid results in 1 hour, which is faster than established ELISA assays measuring SARS-CoV-2 antibody titer (~6 hours) or cell-based neutralization assays (~one to several days). (nature.com)
  • Induction of binding Abs was measured by ELISA and neutralizing activity by PBMC and TZM-bl assays in all serum and vaginal samples. (europa.eu)
  • The animals were intramuscularly administered different vaccine doses, and the control and enzyme-linked immunosorbent assays (ELISA) and pseudovirus neutralization assays were used to determine the serum antibody titers. (news-medical.net)
  • During the live virus neutralization experiments, plaque reduction neutralization assays were used to measure the macaque serum samples, while cytopathic effect neutralization assays were used to determine the neutralizing antibody titers in hamster serum samples. (news-medical.net)
  • Measuring bovine viral diarrhea virus vaccine response: using a commercially available ELISA as a surrogate for serum neutralization assays. (tamu.edu)
  • Recently, standard procedures were adopted for conducting neutralization assays. (who.int)
  • Twenty-four national-level public health laboratories performed routine diagnostic assays on a proficiency testing panel consisting of two modules. (who.int)
  • Fluorescent staining and neutralization assays: Using specific antibodies, these tests are used to further confirm and delineate the type of enterovirus isolated from cell culture. (medscape.com)
  • Molecular methods may soon replace viral culture and neutralization assays used to isolate and type enteroviruses. (medscape.com)
  • Viral culture and neutralization assays are reliable but time-consuming and costly methods. (medscape.com)
  • Procedures -PI status was determined by use of an antigen-capture ELISA (ACE) and confirmed by use of a second ACE, reverse transcriptase-PCR assay of sera, immunohistochemical analysis, and virus isolation from sera. (avma.org)
  • Antibody-capture enzyme-linked immunosorbent assay (ELISA), serum neutralization tests and antigen-capture detection tests, which all test for the presence of Ebola-specific antigens (immune proteins). (thirdage.com)
  • For measuring humoral vaccine response, serum neutralization (SN) measures antibodies that can neutralize BVDV, but relative to enzyme-linked immunosorbent assay (ELISA) is time consuming, technically demanding, and expensive. (tamu.edu)
  • Our objective was to test whether a commercially available BVDV antibody ELISA could be used as a surrogate (or indicator trait) for neutralizing antibodies as measured by SN. (tamu.edu)
  • The BVDV-specific antibody concentration was measured on each serum and plasma sample by (1) a commercially available total antibody ELISA, (2) BVDV-1 SN, and (3) BVDV-2 SN. (tamu.edu)
  • Correlation between the ELISA and SN tests was estimated with a Spearman correlation coefficient. (tamu.edu)
  • Enzyme-linked immunosorbent assay (ELISA) is more sensitive than the neutralization test and can be used as a screening tool, followed by the neutralization test for confirmation. (medscape.com)
  • All neutralization titers mea- cently, a large-scale epidemiologic study addressed sured for BA.1 and BA.2 were above the threshold limit concerns about BA.1 vaccine evasion by showing (Figure). (cdc.gov)
  • Using the Wilcoxon signed-rank test, we as- that 2-dose vaccination and an mRNA vaccine sessed differences between the neutralization titers of booster dose provides at least temporary protection the ancestral strain and the 2 Omicron strains and found against this variant ( 2 ). (cdc.gov)
  • Recently developed cell-free tools can measure antibody titers but cannot necessarily evaluate neutralization, and none of the currently available tools have estimated neutralization activity against the emerging set of SARS-CoV-2 VOCs 8 . (nature.com)
  • The immune sera had equivalent neutralizing titers to both variants. (biorxiv.org)
  • 50% pseudovirus neutralization titers of 16 sera from BNT162b2 vaccine recipients against VSV-SARS-CoV-2-S pseudovirus bearing the Wuhan or lineage B.1.1.7 spike protein. (biorxiv.org)
  • Serum neutralization titers ³32 were considered positive for IBDV exposure. (unl.edu)
  • To achieve this goal, we designed an assay that focuses on antibodies competing with RBD:ACE-2 interactions as a proxy for antibody neutralization 8 (Fig. 1a,b ). (nature.com)
  • Sera of 16 participants in the previously reported German phase 1/2 trial ( 7 ), drawn from eight younger (18-55 yrs) and eight older adults (56-85 yrs) at 21 days after the booster immunization with 30 μg BNT162b2 (Fig S2), were tested for neutralization of SARS-CoV-2 Wuhan and lineage B.1.1.7 spike-pseudotyped VSV by a 50% neutralization assay (pVNT 50 ). (biorxiv.org)
  • In this study, using a live virus assay, we describe the neutralizing antibody response to the B.1.617.1 variant in serum from infected and vaccinated individuals. (biorxiv.org)
  • Prof Wang and his team invented the sVNT assay, trade named cPass TM , which has been granted Emergency Use Authorisation by the US FDA to determine SARS-CoV-2-specific neutralising antibodies in human sera following infection or vaccination. (sciencedaily.com)
  • 2. TNA Relative Neutralization Activity - Estimates relative neutralization activity (RNA) for serum samples tested in the toxin neutralization assay (TNA). (r-project.org)
  • Reverse transcriptase polymerase chain reaction (RT-PCR) assay , which tests for the presence of Ebola RNA (organism-specific genetic material). (thirdage.com)
  • IMPORTANCE Serological diagnostic testing for flaviviral infections is hindered by the need for specialized biocontainment for preparation of reagents and assay implementation. (bvsalud.org)
  • The 'gold standard' method to assess humoral antibody responses fol owing vaccination is the neutralization assay. (who.int)
  • Laboratory testing with a rapid conducted at that time showed that 6.1% of the residents assay suggested that a dengue virus (DENV) was the caus- in nearby regions of Uganda had specifi c antibodies to ative agent. (folkhalsomyndigheten.se)
  • Molecular tests for viral presence through its molecular components are used to diagnose individual cases and to allow public health authorities to trace and contain outbreaks. (wikipedia.org)
  • Positive viral tests indicate a current infection, while positive antibody tests indicate a prior infection. (wikipedia.org)
  • Tests that look for the viral antigens (parts of the virus) are called antigen tests. (wikipedia.org)
  • remarked that for 2003 SARS, "from a diagnostic point of view, it is important to note that nasal and throat swabs seem less suitable for diagnosis, since these materials contain considerably less viral RNA than sputum, and the virus may escape detection if only these materials are tested. (wikipedia.org)
  • Serological antibody tests (ideally home-based diagnostics) are critical to evaluate the response to vaccination and viral infection 2 . (nature.com)
  • Viral tests detect current infection . (cdc.gov)
  • The animal models used to test immunogenicity and antibody responses to viral challenge included BALB/c mice, rhesus macaques, and Golden Syrian hamsters. (news-medical.net)
  • Objective -To detect bovine adenovirus serotype 7 (BAV-7) infections in calves by use of viral isolation and serologic testing. (avma.org)
  • Tests included viral isolation in cell culture from peripheral blood leukocytes (PBL) and detection of serum BAV-7 antibodies by use of microtitration viral neutralization. (avma.org)
  • Following HIV-1 infection, serum neutralizing antibody responses against the evolving autologous viral swarm are generated by the vast majority of infected subjects, usually within the first few months of infection [ 1 - 6 ]. (plos.org)
  • New combination vaccines should induce similar or superior levels of neutralizing antibody in serum for individual protection against paralytic disease and mucosal immunity that effectively decreases viral replication in the intestine and pharynx for population protection against transmission of poliovirus. (who.int)
  • We analyzed serum samples collected of BA.2 seems to occur as a result of mechanisms of during January 26-28, 2022, from 20 (8 male, 12 female) transmissibility other than antibody escape. (cdc.gov)
  • The ratio of the 50% neutralization geometric mean titer (GMT) of the sera against the SARS-CoV-2 lineage B.1.1.7 spike-pseudotyped VSV to that against the Wuhan reference spike-pseudotyped VSV was 0.79, indicating no biologically significant difference in neutralization activity against the two pseudoviruses ( Fig. 1 , Fig. S3, Table S1). (biorxiv.org)
  • In suspected outbreaks, serial serum samples from pigs sometimes are used to show a rising titer against JE. (iastate.edu)
  • We designed a protein biosensor that uses thermodynamic coupling for sensitive and rapid detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in serum. (nature.com)
  • In addition, antibody detection may provide a complementary perspective, along with RT-qPCR testing, in the diagnosis of COVID-19 (24,25). (researchgate.net)
  • This method can be more effective than antigen-detection tests in diagnosing the disease in its acute (early) stage, because patients often die from Ebola before their bodies are able to produce the appropriate antigens. (thirdage.com)
  • Module A contained serum samples spiked with cultured dengue virus (DENV) or chikungunya virus (CHIKV) for the detection of nucleic acid and DENV non-structural protein 1 (NS1) antigen. (who.int)
  • Module B contained human serum samples for the detection of anti-DENV antibodies. (who.int)
  • [ 1 ] The dilute Russel viper venom test (dRVVT) is widely used as another coagulation test for this purpose and is believed to be more specific for LA detection. (medscape.com)
  • Antibody testing is not currently recommended to assess for immunity to SARS-CoV-2 following COVID-19 vaccination or to assess the need for vaccination in an unvaccinated person. (cdc.gov)
  • Antibody tests can detect the presence of these antibodies in serum within days to weeks following acute infection or vaccination. (cdc.gov)
  • Antibody tests are not recommended or authorized by the FDA to assess someone's immunity after COVID-19 vaccination or determine if they need to be vaccinated. (cdc.gov)
  • A new study by researchers in France reports impaired neutralization of two new SARS-CoV-2 variants by antibodies induced by vaccination or natural infection. (news-medical.net)
  • The vaccine was safe and well tolerated, induced potent serum IgG & IgA responses waning post last vaccination, and low and intermittent mucosal IgG, but did not induce neutralizing activity neither in serum nor vaginal samples. (europa.eu)
  • Sera and plasma samples (n=406) were collected from these calves at the time of vaccination and post-vaccination (20-72 days post-vaccination). (tamu.edu)
  • Sera obtained from vaccinees one month after receiving the booster vaccination (third dose of BNT162b2 vaccine) neutralized the Omicron variant to levels that are comparable to thoseobserved for the wild-type SARS-CoV-2 spike protein after two doses. (pfizer.com)
  • however, a reduction in neutralization efficacy is expected for individuals infected by the Gamma variant, highlighting the importance of continuous vaccination even for previously infected individuals. (bvsalud.org)
  • 0.001), with all patients showing neutralization against all tested variants. (lww.com)
  • Our in vitro findings using authentic SARS-CoV-2 variants indicate that in contrast to the currently circulating Delta variant, the neutralization efficacy of vaccine-elicited sera against Omicron was severely reduced highlighting T-cell mediated immunity as essential barrier to prevent severe COVID-19. (medrxiv.org)
  • The three variants were incubated with serum from a range of convalescent COVID-19 subjects, who had mild, moderate and severe-to-critical disease. (news-medical.net)
  • The recent emergence of SARS-CoV-2 variants that are less sensitive to neutralization by convalescent sera or vaccine-induced neutralizing antibody responses has raised concerns. (biorxiv.org)
  • These variants contain mutations arising within the spike protein that are known to increase resistance to antibody neutralization 3 . (biorxiv.org)
  • WHO does not recommend isolation of male or female convalescent patients whose blood has tested negative for Marburg virus. (who.int)
  • Passive transfer of serum antibodies from convalescent patients has been used in the past ( 7 , 8 ), however, this approach is of limited use in a global pandemic emergency. (frontiersin.org)
  • Test analysis is often performed in automated, high-throughput, medical laboratories by medical laboratory scientists. (wikipedia.org)
  • Also, at the end of today's session, participants will be able to apply CDC Zika laboratory testing algorithms when determining which patients with relevant travel history, possible Zika virus exposure, or Zika symptoms, should receive testing. (cdc.gov)
  • On November 7, 2022, dengue virus (DENV), which is not endemic in the continental United States, [ 1 ] was identified in a Maricopa County, Arizona resident by reverse transcription-polymerase chain reaction (RT-PCR) testing at Arizona State Public Health Laboratory (ASPHL). (medscape.com)
  • NEW YORK & MAINZ, Germany--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced results from an initial laboratory study demonstrating that serum antibodies induced by the Pfizer-BioNTech COVID-19 Vaccine (BNT162b2) neutralize the SARS-CoV-2 Omicron variant after three doses. (pfizer.com)
  • Accurate laboratory testing is a critical component of dengue and chikungunya surveillance and control. (who.int)
  • [ 5 ] Laboratory evidence of Zika virus infection was defined as a positive test for Zika virus immunoglobulin M (IgM) and virus specific-neutralizing antibodies or a positive test for Zika virus-specific neutralizing antibodies in an infant sample. (medscape.com)
  • tory testing to the Arbovirus Diagnostic Laboratory at the Over the next 20 years, several ZIKV isolates were Centers for Disease Control and Prevention (CDC, Fort obtained from Aedes spp. (folkhalsomyndigheten.se)
  • The standard for laboratory diagnosis is a mouse neutralization bioassay confirming botulism by isolation of the toxin. (medscape.com)
  • These antigens can replace current antigens derived from live or inactivated virus for safer use in diagnostic testing. (bvsalud.org)
  • The use of these cell lines for production of flaviviral antigens will expand serological diagnostic testing of flaviviruses worldwide. (bvsalud.org)
  • CDC Arboviral Diseases Branch confirmed DENV-3 by plaque reduction neutralization testing. (medscape.com)
  • Our findings demonstrate that a single intramuscular injection in mice of AAV encoding R1a-B6 fused to Fc fragments of different isotypes equipped either, with or without antibody dependent cellular cytotoxicity (ADCC) activity, was able to drive sustained high-level expression (0.5-1.1 mg/mL) in sera with no evidence of reduction for up to 6 months. (frontiersin.org)
  • No reduction in the neutralizing efficacy of the Delta variant was observed when compared to B lineage and a reduced neutralization was observed for the Gamma variant. (bvsalud.org)
  • Antibody responses, including isotypes, were assessed by virus neutralization (VN) and indirect fluorescent antibody (IFA) tests over time before and after re-challenge. (usda.gov)
  • S- isolates in serum samples from persons who received 20210007C). (cdc.gov)
  • COVID-19 testing involves analyzing samples to assess the current or past presence of SARS-CoV-2. (wikipedia.org)
  • Test samples are treated with certain chemicals that allow DNA to be extracted. (wikipedia.org)
  • Archived serum samples were tested at the Poultry Diagnostic and Research Center, University of Georgia, Athens, Georgia, in July 2007. (unl.edu)
  • Maricopa County Environmental Services Department (MCESD) conducted retrospective testing for DENV in samples collected from 21 mosquito pools located within 5 miles (8 km) of patient A's residence during October 1-November 3. (medscape.com)
  • We used an RT-PCR, with primers targeted to the 3' terminal portion of the nucleoprotein gene (N), to test neck-skin samples of nine patients who had rabies in order to validate a diagnostic method that could serve as an additional tool for rabies diagnosis, particularly in antemortem samples. (scielo.br)
  • Open in a separate window Physique 1 Location of Zhejiang Province in China (left) and the location of selected districts (right) within the province where serum samples of healthy persons were collected and tested in 2013 for the presence of severe fever with thrombocytopenia syndrome virusCspecific IgG and IgM. (woofahs.com)
  • All serum samples were unfavorable for SFTSV-specific IgM, whereas 4 (7.4%) of the serum samples were positive for SFTSV-specific IgG (Physique 2). (woofahs.com)
  • Serologic tests that reveal antibody in fetuses also are useful in diagnosis. (iastate.edu)
  • 2020 clinical practice guidelines from the Centers for Disease Control and Prevention on the collection, handling, and testing of specimens for the diagnosis of coronavirus disease 2019 (COVID-19). (medscape.com)
  • We tested 49 known coronavirus disease-19 (COVID-19) patients and 111 prepandemic stored serology specimens. (researchgate.net)
  • Due to numerous mutations in the spike protein, the SARS-CoV-2 variant of concern Omicron (B.1.1.529) raises serious concerns since it may significantly limit the antibody-mediated neutralization and increase the risk of reinfections. (medrxiv.org)
  • However, all do not show the same level of immune evasion, with the UK variant being more susceptible to neutralization than the other two. (news-medical.net)
  • We found that the B.1.617.1 variant is 6.8-fold more resistant to neutralization by sera from COVID-19 convalescent and Moderna and Pfizer vaccinated individuals. (biorxiv.org)
  • Despite this, a majority of the sera from convalescent individuals and all sera from vaccinated individuals were still able to neutralize the B.1.617.1 variant. (biorxiv.org)
  • This suggests that protective immunity by the mRNA vaccines tested here are likely retained against the B.1.617.1 variant. (biorxiv.org)
  • BNT162b2-immune sera neutralized SARS-CoV-2 (USA/WA-1/2020 background strain) with an introduced N501Y mutation as efficiently as SARS-CoV-2 without the mutation ( 6 ). (biorxiv.org)
  • Further, 19 pseudoviruses, each bearing a SARS-CoV-2 S with a different mutation found in circulating strains, were also neutralized as efficiently as non-mutant SARS-CoV-2 S bearing pseudoviruses by BNT162b2-immune sera ( 7 ). (biorxiv.org)
  • Nevertheless, the question remained whether a virus with the full set of mutations in the lineage B.1.1.7 spike would be neutralized efficiently by BNT162b2-immune sera. (biorxiv.org)
  • It is noteworthy that all of them share some escape mutations already known to have emerged under the selection pressure of antibody exposure, both from immune serum or therapeutic antibody use in prolonged survival within immunocompromised individuals, and from the antibodies elicited by natural infection. (news-medical.net)
  • A series of three tests was conducted, using S. D. and Md vira on the same days, with controls in the form of normal serum-virus mixtures and saline-virus mixtures of the same virus dilution as that in the immune serum-virus mixtures. (wiktionary.org)
  • It did react with homologous serum, polyvalent Palyam and virus strain BeAr 263191 (isolated in 1974). (cdc.gov)
  • The two main types of tests detect either the presence of the virus or antibodies produced in response to infection. (wikipedia.org)
  • Rapid self-tests and point-of-care testing are also available and can offer a faster and less expensive method to test for the virus although with a lower accuracy. (wikipedia.org)
  • There are multiple types of tests that look for the virus by detecting the presence of the virus's RNA. (wikipedia.org)
  • The biosensor is a switchable, caged luciferase-receptor-binding domain (RBD) construct that detects serum-antibody interference with the binding of virus RBD to angiotensin-converting enzyme 2 (ACE-2) as a proxy for neutralization. (nature.com)
  • Based on further analysis of ongoing research, WHO recommends that male survivors of Marburg virus disease practise safer sex and hygiene for 12 months from onset of symptoms or until their semen twice tests negative for Marburg virus. (who.int)
  • When assayed using the authentic B.1.351 virus, however, neutralization by plasma from six convalescent donors was markedly weaker, with the 50% inhibitory concentrations (IC50) rising by 6-200 times relative to the original strain. (news-medical.net)
  • The technique of preparing virus suspensions, mixing and holding serum-virus inocula, was identical to that employed by Howitt in neutralization tests of poliomyelitis and equine encephalomyelitis vira . (wiktionary.org)
  • Virus can be identified by neutralization tests in suckling mice or cell culture. (iastate.edu)
  • The U.S. Centers for Disease Control and Prevention (CDC) previously issued travel, testing, and other guidance related to areas of active Zika virus transmission in Florida. (cdc.gov)
  • Pregnant women who have an epidemiologic link to any area of Miami-Dade County after August 1, 2016 should be tested for Zika virus in accordance with CDC guidance ( https://www.cdc.gov/mmwr/volumes/65/wr/mm6529e1.htm?s_cid=mm6529e1_e ). (cdc.gov)
  • Pregnant women with an epidemiologic link to the 4.5-square-mile area of Miami Beach with active Zika virus transmission, after July 14, 2016, should be tested for Zika virus. (cdc.gov)
  • Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles ' by Syed, A., et al. (asm.org)
  • Further comprehensive diagnostic testing, including testing for Zika virus, should comprise future iterations of the EQA. (who.int)
  • Neutralizing activity was more potent in sera from those with critical disease relative to all others, but was maintained in all cases at six months. (news-medical.net)
  • We have previously described R1a-B6, an alpaca-derived single domain antibody (nanobody), that is capable of potent cross-subtype neutralization in vitro of H1N1, H5N1, H2N2, and H9N2 influenza viruses, through binding to a highly conserved epitope in the influenza hemagglutinin stem region. (frontiersin.org)
  • The trimeric conformation and purity of the modified spike protein were tested using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and size-exclusion high-performance liquid chromatography (HPLC). (news-medical.net)
  • test sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA). (biolegend.com)
  • Antibody tests (serology immunoassays) instead show whether someone once had the disease. (wikipedia.org)
  • Antibody tests have public health value for monitoring and evaluating population levels of immunity, as well as clinical utility for patients. (cdc.gov)
  • Antibody tests that have received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) may be used for both public health and clinical purposes. (cdc.gov)
  • Antibody tests are not used for diagnosing a current case of COVID-19. (cdc.gov)
  • However, EUA indications do not preclude use of antibody tests in vaccinated individuals in certain situations. (cdc.gov)
  • In a diagnostic test, sensitivity is a measure of how well a test can identify true positives and specificity is a measure of how well a test can identify true negatives. (wikipedia.org)
  • For all testing, both diagnostic and screening, there is usually a trade-off between sensitivity and specificity, such that higher sensitivities will mean lower specificities and vice versa. (wikipedia.org)
  • Although CEA testing is a cost-effective and widely available diagnostic tumor marker, its lack of sensitivity and specificity precludes any pathognomonic diagnosis. (degruyter.com)
  • Early diagnosis can eliminate the expense of unnecessary diagnostic tests and inappropriate medical treatment [9]. (scielo.br)
  • Diagnostic testing for these viruses is difficult because many of the pathogens require specialized biocontainment. (bvsalud.org)
  • This information is in contrast to a study in Wuhan, China that found 10% of patients lost SARS-CoV-2 antibodies within weeks of infection (12) , although different serology tests were used in this case. (researchgate.net)
  • Neutralization against B.1.1.7 was detectable in all kidney transplant recipients with seroconversion, with a median serum dilution that reduces infection of cells by 50% of 80 (interquartile range, 80-320). (lww.com)
  • In a recent study published in the journal npj Vaccines , researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer. (news-medical.net)
  • In addition to the presence of Ebola symptoms and recent travel to or from an Ebola-affected region, doctors can use several tests to confirm an Ebola diagnosis. (thirdage.com)
  • The person with the positive test result reported no travel during the 2 weeks preceding symptom onset. (medscape.com)
  • In 36 kidney transplant recipients with seroconversion, neutralization against B.1.1.7 ( α ), B.1.351 ( β ), and B.1.617.2 ( δ ) was determined on VeroE6 cells and compared with neutralization in 25 healthy controls. (lww.com)
  • In contrast, only 23 of 36 (64%) and 24 of 36 (67%) kidney transplant recipients showed neutralization against B.1.351 and B.1.617.2, respectively, with median serum dilutions that reduce infection of cells by 50% of 20 (interquartile range, 0-40) and 20 (interquartile range, 0-40), respectively. (lww.com)
  • The well-known N301Y mutation by itself does not appear to be responsible for resistance to neutralization by vaccine-induced antibodies. (news-medical.net)
  • Lateral-flow antigen tests have been introduced, but they are used primarily as binary qualitative tests and report only binding between antibody and antigen rather than neutralization 7 . (nature.com)
  • At both time points, D614G and B.1.1.7 strains showed equal sensitivity to the sera, but with large inter-individual variations over two orders of magnitude. (news-medical.net)
  • At what times during infection is SARS-CoV-2 detectable and no longer detectable using RT-PCR-based tests? (crossref.org)
  • Produced from sera of goats pre-immunized with highly pure (>98%) recombinant Rat IL-6. (prosci-inc.com)
  • Here, we investigated SARS-CoV-2-S pseudoviruses bearing either the Wuhan reference strain or the B.1.1.7 lineage spike protein with sera of 16 participants in a previously reported trial with the mRNA-based COVID-19 vaccine BNT162b2. (biorxiv.org)
  • In this study, two H7N9 split virion vaccines with or without AS03 adjuvant were tested in the naive ferret model. (nature.com)
  • µg sizes: 0.2 mg/mL test sizes: lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool. (biolegend.com)
  • We found no subsequent infections when we used serological and molecular tests to evaluate close contacts. (bvsalud.org)
  • This variation has likely significantly impacted reported statistics, including case and test numbers, case fatality rates and case demographics. (wikipedia.org)
  • The time between the booster dose and serum sampling high number of spike mutations and indications of was 42 (IQR 40-42) days. (cdc.gov)
  • and 4) advised providers to test for and report suspected DENV to MCDPH. (medscape.com)
  • mosquitoes collected in a professional BG-Sentinel mosquito trap § tested negative for DENV by RT-PCR. (medscape.com)
  • Among 20 laboratories testing Module A, 17 (85%) correctly detected DENV RNA by reverse transcription polymerase chain reaction (RT-PCR), 18 (90%) correctly determined serotype and 19 (95%) correctly identified CHIKV by RT-PCR. (who.int)
  • Neutralization tests, utilizing a hyperimmune horse serum and a hyperimmune rabbit serum, were conducted with the two vira . (wiktionary.org)
  • The second and more sensitive method is to neutralize the inhibitor activity by increasing the amount of phospholipid, as is done in the platelet neutralization procedure (PNP) or the rabbit brain neutralization procedure (RBNP). (medscape.com)
  • Individual jurisdictions have adopted varied testing protocols, including whom to test, how often to test, analysis protocols, sample collection and the uses of test results. (wikipedia.org)
  • Table 4 shows the results of these tests, which show convincingly that the vira are related, as could be expected, but certainly not identical. (wiktionary.org)
  • Results of prenatal and newborn testing to rule out other congenital infections were available for some infants and their mothers. (medscape.com)
  • This is based on evidence showing that no single test is sensitive for detecting all LA. However, the risk of false-positive results increases to an unacceptable level if more than 2 screening tests are performed. (medscape.com)
  • For testing human IL-2 in serum or plasma, BioLegend's LEGEND MAX™ Kit (Cat. (biolegend.com)