• For example, a population set provides information on genetic variation within an organism, while a phylogenetic set may contain sequences, and their alignment, of a single gene obtained from several related organisms. (unt.edu)
  • A collection of human gene-specific reference genomic sequences. (unt.edu)
  • A public registry of nucleic acid reagents designed for use in a wide variety of biomedical research applications, together with information on reagent distributors, probe effectiveness, and computed sequence similarities. (unt.edu)
  • Endoproteinase-cleaved peptides of the APO-1 protein were subjected to amino acid sequencing, and corresponding oligonucleotides were used to identify a full-length APO-1 cDNA clone from an SKW6.4 cDNA library. (uni-regensburg.de)
  • A high number of specific clones was obtained after immunization with a pool of nine mimotopes, and the resulting mAbs were shown to recognize several 16- and 27-mer peptides derived from natural HVR1 sequences isolated from patients with acute and chronic HCV infection, suggesting that HVR1 mimotopes were efficient antigenic and immunogenic mimics of naturally occurring HCV variants. (jimmunol.org)
  • Prospective studies of serological responses to synthetic oligopeptides derived from HVR1 sequences of patients with acute and chronic HCV infection showed apparently extensive serological cross-reactivity for unrelated HVR1 peptides in the majority of the patients ( 3 , 4 , 5 , 6 , 7 , 8 , 9 ). (jimmunol.org)
  • With the advent of the post genome era and the development of sequencing technology, how to find all forms of miRNAs from millions of reads has become one of the challenging topics in bioinformatics. (springer.com)
  • Computer analysis of the uvrD coding sequence has indicated that it contains seven conserved motifs that are shared by a superfamily of proteins involved in DNA metabolism ( 16 ). (asm.org)
  • Motifs IA, IB, and II, previously identified as Walker A and Walker B sequences, respectively, are conserved segments found in many nucleoside triphosphate-binding proteins and all helicases characterized to date ( 14 , 15 , 46 ). (asm.org)
  • Combining expression and sequence data: searching for motifs in expression clusters (Tavazoie), linear contribution of motifs to expression levels (Bussemaker), combinations of motifs (Pilpel). (indiana.edu)
  • There is a high level of sequence homology (98-100%) between D4Z4 repeats from the 4q35 and the 10q26 D4F104S1 loci. (barnardhealth.us)
  • DNA sequencing was successful in identifying a unique BluI restriction site present only in each copy of the 10q26-derived repeat units and a XapI site in all 4q35-derived repeats. (barnardhealth.us)
  • Our analyses indicate that these rearrangements were produced by non-homologous recombinational events occurring between short (2-7 bp) sequence repeats at the two termini of the deletion which leave one copy of the repeat in the mutant gene. (nih.gov)
  • Typically, vector systems package versions of the cognate viral genome, where the majority of viral RNA sequences have been removed. (asm.org)
  • We propose the name NUPAVs (nuclear sequences of plasmid and viral origin) for these objects, by analogy to NUMTs (nuclear copies of mitochondrial DNA) and NUPTs (nuclear copies of plastid DNA, in plants) of organellar origin. (asm.org)
  • We propose that this region was formed by the capture of plasmid and viral sequences by the same mechanism that captures mitochondrial DNA to form NUMTs ( 43 , 65 ). (asm.org)
  • Based on the functional properties of the integrase of bacteriophage lambda, on the analysis of the nucleotide sequence of the junction fragments and of the target before insertion and after excision, a model is proposed for ORF2-catalysed excision of Tn1545 and related conjugative transposons. (nih.gov)
  • In this report, we provide an analysis of the nucleotide sequence for a 57,988-bp region. (asm.org)
  • Kluyveromyces polysporus ) ( 49 ), we were therefore surprised to find the genomic region we describe here, which contains integrated fragments of several plasmid- and virus-like sequences. (asm.org)
  • Conversely, an organism that is further removed evolutionarily from another organism is likely to display a greater divergence in the sequence of the orthologs being studied. (wikipedia.org)