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  • nucleotides
  • classical genetics cloning codominance codon A series of three nucleotides in a coding region of a nucleid acid sequence which code for a particular amino acid or stop signal during protein synthesis. (wikipedia.org)
  • variations
  • Diagnostic errors can occur due to rare sequence variations. (arupconsult.com)
  • Motivation: Advances of next generation sequencing technologies and availability of short read data enable the detection of structural variations (SVs). (ovid.com)
  • When DNA sequencing was introduced, it opened the door to finding smaller and incredibly more sequence variations including SNPs and minisatellites. (wikipedia.org)
  • Humans
  • Such deletions in humans are referred to as hCONDELs may be responsible for the anatomical and behavioral differences between humans, chimpanzees and other mammals. (wikipedia.org)
  • Syndrome
  • However, the autosomal dominant cases are also categorized under a more commonly diagnosed group called 22q11.2 deletion syndrome. (wikipedia.org)
  • Some researchers consider Opitz G/BBB syndrome to be a type of 22q11.2 deletion syndrome (a slightly different and broader disease). (wikipedia.org)
  • regulatory
  • These transcription factor binding sites (TFBS), or regulatory motifs, have proven hard to identify, primarily because they are short in length, and can show sequence variation. (wikipedia.org)
  • phylogeny
  • In 1973, Sankoff and Robert Cedergren developed a joint estimation method for phylogeny and multiple sequence alignment of 5S ribosomal RNA, laying the algorithmic foundations of comparative genomics. (wikipedia.org)
  • lengths
  • b_{m}} be the sequences to be aligned, where n {\displaystyle n} and m {\displaystyle m} are the lengths of A {\displaystyle A} and B {\displaystyle B} respectively. (wikipedia.org)
  • ancestral
  • Archaea), it can be inferred whether the indel is an insert or a deletion, and which of these two groups A, B, C or X, Y, Z is ancestral. (wikipedia.org)