• Septin 2, also known as SEPT2, is a protein which in humans is encoded by the SEPT2 gene. (wikipedia.org)
  • SEPT2 can hetero-oligomerize with SEPT6 and SEPT7 to form filaments. (wikipedia.org)
  • SEPT2 interacted with SEPT6 through its C-terminal coiled-coil domain. (wikipedia.org)
  • Knockdown of SEPT2, SEPT6, and SEPT7 in causes actin stress fibers to disintegrate and cells to lose polarity. (wikipedia.org)
  • SEPT2 has been shown to interact with: SEPT6 SEPT7, and SEPT9. (wikipedia.org)
  • Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). (nih.gov)
  • 3 disease terms (MeSH) has been reported with SEPT2 gene. (cdc.gov)
  • In mice that lack the Sept2/ARTS gene, stem cells involved in wound healing live longer and wounds heal faster and more thoroughly than in normal mice. (nih.gov)
  • This confocal microscopy image from a mouse lacking the Sept2/ARTS gene shows a tail wound in the process of healing. (nih.gov)