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  • epithelial cell
  • Here we describe a method to conditionally induce epithelial cell transformations and the subsequent live imaging of innate immune cell interaction with HRAS G12V expressing skin cells in zebrafish larvae. (jove.com)
  • Factors derived from Escherichia coli Nissle 1917, grown in different growth media, enhance cell death in a model of 5-fluorouracil-induced Caco-2 intestinal epithelial cell damage. (nih.gov)
  • rats
  • This study aimed at studying the potential neuroprotective effect of Rutin hydrate (RH) alone or in conjugation with α-tocopherol against cadmium chloride (CdCl2)-induced neurotoxicity and cognitive impairment in rats and to investigate the mechanisms of action. (readbyqxmd.com)
  • Effects of commercially produced almond by-products on chemotherapy-induced mucositis in rats. (nih.gov)
  • Taxol
  • In a pilot RNAi-based screen we found that knockdown of retinophilin (rtp), which encodes a MORN (membrane occupation and recognition nexus) repeat-containing protein, protects axons from degeneration in the presence of taxol. (nih.gov)
  • researchers
  • INDIANAPOLIS - Indiana University cancer researchers have been awarded $2.9 million to study the debilitating side effects caused by chemotherapy that affect a significant number of cancer patients. (iu.edu)
  • To find out if this drug inhibits colon cancer, researchers from University of Texas Health Sciences Center in Houston conducted a study involving unmodified indomethacin and indomethacin modified with phosphatidylcholine to protect against NSAID injury in the gastrointestinal tract. (eurekalert.org)
  • ATF3
  • Dr. Hai and her team have found that the expression of ATF3 in non-cancer stromal cells is induced by chemotherapeutic agents, and this induction is required for the agents to exert their devastating effect. (osu.edu)
  • potent
  • Cisplatin (cis-diamminedichloroplatinum) is a potent chemotherapy drug, which is an alkylating agent that is used extensively against many solid tumors (including bladder, testicular, ovarian, and mammillary tumors), hematologic malignancies, and cancers of the head and neck. (tinnitusjournal.com)
  • mucositis
  • Chemotherapy often induces damage to the oral cavity, resulting in oral mucositis, oral infection, and salivary gland dysfunction. (wikipedia.org)
  • Effects of Supernatants from Escherichia coli Nissle 1917 and Faecalibacterium prausnitzii on Intestinal Epithelial Cells and a Rat Model of 5-Fluorouracil-Induced Mucositis. (nih.gov)
  • cancers
  • While it only occurs in certain classes of chemotherapies used in some cancers, the treatments are among the more common, such as taxanes for breast cancer, and platinum agents for colorectal tumours (see table below). (cancerworld.net)
  • There are about 300,000 testicular cancer survivors worldwide, as well as millions of survivors of other cancers who have been treated with cisplatin-based chemotherapy. (curetoday.com)
  • The drug is used to treat ovarian, bladder, head and neck and small cell lung cancers, as well as germ cell tumors and testicular cancer, in which it's often used as part of a chemotherapy regimen following surgery and radiation. (curetoday.com)
  • tumor
  • The cancer is not only difficult to detect but treatment is often complicated by mutations in the p53 tumor suppressor gene that make the cancer cells resistant to chemotherapy. (eurekalert.org)
  • Tumor cells appear to have co-opted this neural protein channel, which is associated with multiple types of cancer, to protect themselves against oxidative stress," said senior study author Joan Brugge, the Louise Foote Pfeiffer Professor of Cell Biology at HMS. (eurekalert.org)
  • apoptosis
  • The Ginkgo biloba extract (EGb 761 o Ginkgoselect®) is known to have antioxidant proprieties with a free radicals scavenging effect, and protecting cells against apoptosis. (unife.it)
  • Apoptosis factor data imply that FZE protected Schwann cells through the mitochondria pathway. (jove.com)
  • regimen
  • Influence of oak maturation regimen on composition, sensory properties, quality, and consumer acceptability of cabernet sauvignon wines. (nih.gov)
  • vitro
  • And in vitro, FZE was also found to protect Schwann cells against high glucose injury. (jove.com)
  • nerve
  • What they eventually found astonished them: IL-17c was stimulating the growth of nearby sensory nerve fibers, and the herpes virus itself was goading skin cells to produce it. (fredhutch.org)
  • Molecular
  • An expert in how plants cope with heat, Vierling's interest for many years has been small heat shock proteins (HSPs), which accumulate in plants at high temperatures and appear to act as "molecular chaperones" to protect other proteins from damage. (phys.org)
  • occurs
  • Thus, in current clinical practice, when ototoxicity occurs, then use of the drug is discontinued or chemotherapy is continued using a different drug. (tinnitusjournal.com)
  • Lithium induced hypothyroidism occurs most often resolves with prompt recognition and prompt surgical evacuation of a specific recommendation on which to evaluate botulinum toxin were ine ective. (roanokechowan.edu)
  • effects
  • However, a protocol has yet to be developed to protect hearing from the effects of cisplatin. (tinnitusjournal.com)
  • However, the target molecule (receptor) of DIFs is unknown and it is not clear even in Dictyostelium how DIFs induce antiproliferative effects and cell differentiation. (chemdiv.com)
  • pathways
  • They also showed that the compound's potency comes from its ability to induce crosstalk between PDAC cell death pathways. (eurekalert.org)
  • cell
  • Normal and pathological stressors engage the AMP-activated protein kinase (AMPK) signaling axis to protect the cell from energetic pressures. (tdl.org)
  • Differentiation-inducing factors (DIFs) were identified in Dictyostelium discoideum as the morphogens required for stalk cell differentiation . (chemdiv.com)
  • DIF-1 and /or DIF-3 strongly inhibit proliferation and induce differentiation in several leukemia cells, including the murine erythroleukemia cell line B8, human leukemia cell line K562, and human myeloid leukemia cell line HL-60 . (chemdiv.com)
  • drug
  • Recent studies have suggested that involvement of neuroinflammatory processes in brain dysfunction is induced by misuse of this drug. (readbyqxmd.com)
  • pain
  • Injury-induced sensitization of nociceptors contributes to pain states and the development of chronic pain. (tdl.org)