• Odorants, which are mostly small lipophilic molecules, enter the mucus flow and reach the odorant receptors on sensory neurons. (wikipedia.org)
  • In addition to the olfactory neurons, the epithelium is composed of supporting cells, Bowman glands and ducts unique to the olfactory epithelium, and basal cells that allow for the regeneration of the epithelium, including the olfactory sensory neurons. (medscape.com)
  • Individual sensory neurons of the transplants revealed variable intensity of the AChE staining, thus resembling the pattern of AChE activity in normal DRG. (iospress.com)
  • BuChE activity was mostly localized on the surface of sensory neurons in the ring of satellite cells. (iospress.com)
  • Some BuChE positive blood vessels penetrated into the DRG, and were observed around sensory neurons. (iospress.com)
  • The results showed a considerable viability and adaptability of the sensory neurons in the new environment after a long-term transplantation. (iospress.com)
  • The olfactory mucosa, lining a portion of the nasal cavity, houses the primary olfactory sensory neurons responsible for odor transduction, along with supporting cell populations. (bvsalud.org)
  • The neurogenic cranial placodes are a unique transient epithelial niche of neural progenitor cells that provide rise to multiple derivatives from the peripheral nervous system specially the sensory neurons. (crispr-reagents.com)
  • In vertebrate embryos neurons are produced from three resources the neuroepithelium from the neural pipe Arry-380 the neural crest as well as the ectodermal cranial placodes. (crispr-reagents.com)
  • While some placodes contribute non-neuronal cell types to cranial sensory organs the neurogenic placodes that contribute sensory neurons to the PNS include the trigeminal epibranchial otic and olfactory placodes. (crispr-reagents.com)
  • Placode-derived neurons enter the mesenchyme to co-mingle with neural crest cells to establish cranial ganglia the sensory nervous system Arry-380 component of cranial nerves. (crispr-reagents.com)
  • Roots and derivatives of neurogenic placodes Progenitors inside the neurogenic placodes bring about various kinds of sensory neurons/cells which donate to the cranial ganglia the internal ear as well as the olfactory epithelium. (crispr-reagents.com)
  • Sensory neurons from the placodes delaminate in the epithelium migrate and condense to create the cranial ganglia. (crispr-reagents.com)
  • The only real derivatives of both trigeminal and epibranchial placodes are sensory neurons from the cranial ganglia (D'Amico-Martel and Noden 1983 Harlow and Barlow 2007 The neural contribution from the otic placode includes both supplementary sensory locks cells from the internal ear canal and sensory neurons from the cochleovestibular ganglion (CVG) which delaminate in the epithelium from the invaginated otic vesicle. (crispr-reagents.com)
  • 2004 Trigeminal placode Although some from the cranial placodes make cell types apart from neurons sensory neurons will be the exclusive derivative from the trigeminal placodes. (crispr-reagents.com)
  • The neural crest (NC) gives rise to many derivatives including the neurons and glia of the sensory and autonomic ganglia of the peripheral nervous system, enteric neurons and glia, melanocytes, and the cartilaginous, bony and connective tissue of the craniofacial skeleton, cephalic neuroendocrine organs, and some heart vessels. (monash.edu)
  • These receptors are present on dendrites of olfactory sensory neurons found in the main olfactory or vomeronasal sensory epithelia, and are involved in the odorant, trace amineassociated receptor and vomeronasal type 1 receptor superfamilies. (nutrition-nutritionists.com)
  • The newly described formyl peptide receptor-related genes and vomeronasal sensory neurons, are found in multiple mammalian species. (nutrition-nutritionists.com)
  • Olfaction is maintained through life because, unlike for other sensory neuroepithelia, olfactory neurons have a unique capacity to regenerate after trauma. (hal.science)
  • understanding the immune contributions of olfactory sensory neurons (OSNs) in teleosts against viruses. (unm.edu)
  • Tatti R , Bhaukaurally K, Gschwend O , Seal RP , Edwards RH , Rodriguez I , Carleton A . A population of glomerular glutamatergic neurons controls sensory information transfer in the mouse olfactory bulb. (neurotree.org)
  • One of the neuron types we study, the spinal sensory Rohon-Beard (RB) neurons, make an excellent model to investigate guidance mechanisms because they have stereotyped axon arbor morphology and can be readily imaged in vivo. (wisc.edu)
  • Our findings support a model for PRC2-dependent mechanisms promoting sensory neuronal differentiation in an adult neurogenic niche. (bvsalud.org)
  • Sustentacular cells thus represent a potential entry door for SARS-CoV-2 in a neuronal sensory system that is in direct connection with the brain. (unige.ch)
  • spon1b:GFP larval expression patterns starts in early development in specific neuronal structures of the developing brain associated with sensory-motor modulation. (biomedcentral.com)
  • It is a specialized pseudostratified neuroepithelium containing the primary olfactory receptors. (medscape.com)
  • Dorsal portion of the neuroepithelium that gives rise to sensory nuclei of the spinal cord and brain stem. (mhmedical.com)
  • Methodology/Principal Findings: We present evidence that neural crest (NC) competence can be acquired very early when human embryonic stem cells (hESCs) are selectively neuralized towards dorsal neuroepithelium in the absence of feeder cells in fully defined conditions. (monash.edu)
  • The saccular macula is an elliptical thickened area of sensory epithelium that lies on the anterior vertical wall of the saccule. (medscape.com)
  • the sensory epithelium lies on the crista ampullaris. (medscape.com)
  • The vestibular sensory epithelium is located on the maculae of the saccule and utricle and the cristae of the semicircular canals. (medscape.com)
  • and 2) delamination from your epithelium whereby cells detach from their epithelial neighbors and escape through breaks in the basement membrane into the mesenchyme as migratory sensory neuroblasts in a process different from the epithelial to mesenchyme transition (EMT) seen in neural crest cells (Graham et al. (crispr-reagents.com)
  • 2007 In Arry-380 this focused review we will only briefly introduce the neurogenic placodes and then comprehensively examine how the Notch FGF Wnt and BMP signaling protein families direct sensory neurogenesis and delamination from your placodal epithelium where the pathways are conserved where they diverge and what we still have to find out about the differentiation procedure. (crispr-reagents.com)
  • The tip of the epithelium harbors clusters of CD8α + cells whereas few numbers are found in the neuroepithelium. (unm.edu)
  • the mechanism by which synaptic ribbons orchestrate sensory receptor neurotransmission remains unclear ( Parsons and Sterling, 2003 ). (jneurosci.org)
  • afferent is not synonymous with sensory , which means related to processing information from a receptor sheet (e.g., body surface or retina). (mhmedical.com)
  • They are similar to the four known olfactory receptor gene classes, these genes encode seven-transmembrane proteins, and are characterized by monogenic transcription and a punctate expression pattern in the sensory neuroepithelium. (nutrition-nutritionists.com)
  • To test whether the olfactory neuroepithelium may represent a target of the virus, we generated RNA-seq libraries from human olfactory neuroepithelia, in which we found substantial expression of the genes coding for the virus receptor angiotensin-converting enzyme-2 (ACE2), and for the virus internalization enhancer TMPRSS2. (unige.ch)
  • iii) Radial arbors: Receptor cells in an electrosensory neuroepithelium covering the basal pole of each ampullary organ were innervated by bouton endings of radial neurites, unmyelinated and submicron, forming a thin curviplanar lamina distal to the lectin+ basal lamina. (ohio.edu)
  • We also address the differing roles of additional pathways like the Wnt and BMP signaling family members during sensory neurogenesis and neuroblast delamination in the differing placodes. (crispr-reagents.com)
  • RESULTS: We show that retinoic acid signaling, although dispensable for initial induction of the olfactory placode, plays a key role in neurogenesis within this neuroepithelium. (hal.science)
  • Each olfactory division contains several types of sensory cell identified by the receptors and other proteins they express, the connections they make in the olfactory part of the brain, and the chemical stimuli to which they respond. (nutrition-nutritionists.com)
  • SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain. (unige.ch)
  • Certain sensory receptors contain many transducers, converging onto few afferents. (ohio.edu)
  • The olfactory neuroepithelium, which lines the posterior nasal cavity, is exposed to a wide range of odorants and airborne toxic compounds. (wikipedia.org)
  • That portion of the nasal mucosa containing the sensory nerve endings for SMELL, located at the dome of each NASAL CAVITY. (lookformedical.com)
  • The thalamic complex is the major sensory relay station in the vertebrate brain and comprises three developmental subregions: the prethalamus, the thalamus and an intervening boundary region - the zona limitans intrathalamica(ZLI). (silverchair.com)
  • Another main research area in the lab is aimed at understanding mechanisms of neural crest cell (NCC) migration, and in particular the epithelial to mesenchymal transition (EMT) that NCCs undergo to delaminate from the neuroepithelium and begin migration. (wisc.edu)
  • A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. (lookformedical.com)
  • After initial induction of this panplacodal primordium into individual placodes each placode is specified for a unique sensory fate. (crispr-reagents.com)
  • Placodes talk about the epithelial quality from the CNS neuroepithelium as well as the transient migratory character from the neural crest. (crispr-reagents.com)
  • Please check the GO:0045177 "apical part of cell" annotation from MGI:3037622/PMID 15037549, which states, "beta-catenin, f-actin, and myosin II-B localize predominantly to the apical-junctional complex in normal neuroepithelium (Fig. 6E-G)." Is there additional supporting evidence for the 45177 annotation? (geneontology.org)
  • Mouse Ctnnb1: Is GO:0050909 "sensory perception of taste" actually shown in PMID 17128274? (geneontology.org)
  • This diversity of sensory cells in the nose has given rise to the concept of olfactory subsystems, each dedicated to a particular chemosensory role. (nutrition-nutritionists.com)
  • Using stereomicroscopy and microscopic examination of plastic sections, dextran dyes dispersed in SNOT are demonstrated in the neuroepithelium of the nose and olfactory bulb of B6;129P2-Omp(tm3Mom)/MomJ mice after intranasal instillation in SNOT. (cdc.gov)
  • These early migratory Neural Crest Stem Cells (emNCSCs) uniformly upregulate Sox10 and vimentin, downregulate N-cadherin, and remodel F-actin, consistent with a transition from neuroepithelium to a mesenchymal NC cell. (monash.edu)
  • The bodies of the cochlear sensory cells resting on the basilar membrane are surrounded by nerve terminals, and their approximately 30,000 axons form the cochlear nerve. (cloudaccess.net)
  • Auditory damage is caused by viral replication in sensory neuroepithelium and a subsequent host immune response. (radiologykey.com)
  • However, the cell bodies and central axons develop normally, indicating that LIM transcription factors function specifically to control peripheral sensory axon outgrowth. (wisc.edu)
  • This workshop explored the viability of studying the effects of altered gravitational exposure on sensory-motor function in genetically altered experimental model systems. (nih.gov)
  • During the development of this organ, highly differentiated, information-processing structures are formed - such as the cerebrum in the telencephalon, the tectum in the mesencephalon and the cerebellum in the rhombencephalon - which all have to be wired up with the information-generating sensory systems. (silverchair.com)
  • All higher brain functions including the integration and processing of sensory and motor information, the memory storage and retrieval, and the regulation of emotional and drive states take place at the telencephalic level. (intechopen.com)
  • The olfactory neuroepithelium is located at the upper area of each nasal chamber adjacent to the cribriform plate, superior nasal septum, and superior-lateral nasal wall. (medscape.com)
  • On June 21 and 22, 1999, the National Institute on Deafness and Other Communication Disorders (NIDCD) and the Life Sciences Division of the National Aeronautics and Space Administration (NASA) co-sponsored a program planning workshop, "Role of Transgenic and Knockout Studies in Understanding Sensory-Motor Performance in Altered Gravitational Performance. (nih.gov)
  • The ear is the sensory organ responsible for hearing and the maintenance of equilibrium, via the detection of body position and of head movement. (cloudaccess.net)
  • [ 2 ] Given the aging of the US population, therefore, it stands to reason that a significant and increasing number of individuals will experience age-related sensory loss. (medscape.com)