Cell AgingTumor Suppressor Protein p53Cyclin-Dependent Kinase Inhibitor p16Cell Line, TumorFibroblastsTelomereAgingTumor Markers, BiologicalTumor Necrosis Factor-alphaTumor BurdenTelomeraseCell ProliferationCyclin-Dependent Kinase Inhibitor p21Plant LeavesTumor Suppressor Proteinsbeta-GalactosidaseAging, PrematureGenes, Tumor SuppressorCells, CulturedDNA DamageCell Transformation, NeoplasticSignal TransductionWilms TumorNeoplasms, ExperimentalCell DivisionNeoplasmsCell CycleCell LineTumor Suppressor Protein p14ARFCarcinoid TumorRetinoblastoma ProteinApoptosisPhenotypeTelomere ShorteningMutationTumor MicroenvironmentNeuroendocrine TumorsBrain NeoplasmsRNA, MessengerReverse Transcriptase Polymerase Chain ReactionDown-RegulationTime FactorsMice, Inbred C57BLOxidative StressChlorophyllMammary Neoplasms, ExperimentalRNA, Small InterferingGene Expression Regulation, PlantEthylenesCell Cycle CheckpointsBlotting, WesternTransplantation, HeterologousNeovascularization, PathologicNeoplasm ProteinsRNA InterferenceUp-RegulationReactive Oxygen SpeciesGene Expression ProfilingModels, BiologicalDNA-Binding ProteinsAdenocarcinomaNeoplasm MetastasisLongevityGene Expression RegulationGene Expression Regulation, NeoplasticGenes, rasGenes, p53Cell SurvivalMice, Inbred BALB CXenograft Model Antitumor Assaysras ProteinsSkin NeoplasmsTranscription FactorsMolecular Sequence DataArabidopsisFibrosarcomaMice, NudeTransfectionGastrointestinal Stromal TumorsImmunohistochemistryGene ExpressionColonic NeoplasmsPlant Growth RegulatorsBase SequenceMice, KnockoutCell Line, TransformedSirtuin 1OncogenesFlow CytometryCell Cycle ProteinsPlant ProteinsGene Knockdown TechniquesFlowersPlants, Genetically ModifiedPromoter Regions, GeneticLiver NeoplasmsAntigens, NeoplasmArabidopsis ProteinsMice, SCIDDisease Progression