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  • extragonadal
  • However, GCTs, including seminomas, can occur in extragonadal sites along the midline of the body, following the embryologic migration route of its precursor cells -- the primordial germ cells. (medscape.com)
  • recurrence
  • A review of previously published studies found that 17% of seminoma patients managed by surveillance experienced a cancer recurrence. (unm.edu)
  • A 63-year-old man was referred to Nagoya University Hospital for treatment of a recurrence of resected seminoma. (biomedcentral.com)
  • Early Stage Testicular Seminoma: A Multicenter Review of Treatment Outcomes and Patterns of Recurrence" by M. Kim, E. Wuthrick et al. (jefferson.edu)
  • Purpose/Objective(s): Although overall survival for early stage testicular seminoma is generally excellent, certain pathologic factors can increase recurrence risk for those undergoing observation, while radiation therapy (RT) can be associated with long-term morbidity. (jefferson.edu)
  • Cancer
  • Patients with Stage I seminoma have a primary cancer that is limited to the testes and is curable in more than 95% of individuals. (unm.edu)
  • It is important to understand that a few patients with Stage I seminoma already have small amounts of cancer that have spread into the lymph nodes and cannot be detected with any of the currently available tests. (unm.edu)
  • 21st century
  • For unclear reasons, the overall incidence of seminoma has increased progressively in the 21st century in several different countries. (medscape.com)
  • Incidence
  • Overall, the incidence of seminoma is 6- to 10-fold higher in white than black persons, which is observed in all age groups. (medscape.com)
  • GCTs
  • [ 5 ] Interestingly, high economic status represents an important association with the development of GCTs overall and seminoma specifically. (medscape.com)