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  • cannot
  • However, because of the deficiency, the final intermediate of the GABA degradation pathway, succinic semialdehyde, accumulates and cannot be oxidized to succinic acid and is therefore reduced to gamma-hydroxybutyric acid (GHB) by gamma-hydroxybutyric dehydrogenase. (wikipedia.org)
  • glutamic
  • L-Glutamic-gamma-semialdehyde can also be converted to or be formed from the amino acids L-ornithine (EC 2.6.1.13) and L-proline (EC 1.5.99.8 and EC 1.5.1.2). (hmdb.ca)
  • phosphate
  • Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate. (rcsb.org)
  • pathway
  • The GC-MS data also shows the presence of catechol and 2-hydroxymuconic semialdehyde , which confirms the established pathway of benzene biodegradation. (thefreedictionary.com)
  • 2-amino-3-carboxymuconic acid semialdehyde is an intermediate metabolite of the tryptophan-niacin catabolic pathway. (hmdb.ca)
  • acid
  • The presence of Catechol-1,2-dioxygenase (C12D) or Catechol-2,3-dioxygenase (C23D) was detected by the formation of products cis-cis muconic acid and 2-hydroxymuconic semialdehyde (2-HMS) at 260 nm and 375 nm, respectively (Santos and Linardi, 2004). (thefreedictionary.com)