• This moiety is the mainly responsible for the antibacterial properties of all these molecules, due to their ability to block the bacterial cell wall synthesis as a result of their covalent binding to penicillin-binding proteins (PBPs), which are essential enzymes involved in the terminal steps of the synthesis of peptidoglycan, the main component of the bacterial cell wall [ 9 ] . (encyclopedia.pub)
  • It has little clinically relevant in vitro activity against bacteria due to its reduced affinity to penicillin-binding proteins. (cathaydrug.com)
  • A semi-synthetic antibiotic related to penicillin. (nih.gov)
  • Mezlocillin sodium is a broad-spectrum penicillin antibiotic. (chemicalkaikeshop.com)