Selenium study. Medical search. Frequent questions

Early stage cancers were better halted, but age made no difference, as young and old alike benefited from selenium supplementation. (naturalnews.com)
The conclusion was that selenium supplementation did not protect against the development of further skin cancers, but it did preclude incidences of, and deaths from, other types of cancer. (naturalnews.com)
Men should avoid selenium or vitamin E supplementation at doses that exceed recommended dietary intakes," Dr. Eric Klein, chairman of the Glickman Urological and Kidney Institute at the Cleveland Clinic, and his colleagues wrote in their study, published today (Feb. 21) in the Journal of the National Cancer Institute. (livescience.com)
Given the risks and lacking evidence of benefits for other diseases, men older than 55 should avoid supplementation with either vitamin E or selenium at doses that exceed recommended dietary intakes, the researchers said. (livescience.com)
Supplementation of Q10 and Selenium over a 4-year period could halve cardiovascular mortality. (vitalraadet.dk)
The article was an offshoot of the sensational article by researcher Dr. Urban Alehagen and colleagues from 2015 , who showed massive cardiovascular protection with supplementation of Q10 in combination with selenium. (vitalraadet.dk)
I summarized several studies, which found that selenium supplementation reduced inflammation and damage to thyroid tissue, lowered thyroid antibody levels in the blood, and improved the conversion of T4 to T3. (chriskresser.com)
These preliminary studies show the positive effects of selenium supplementation on inflammatory activity in autoimmune thyroid conditions, but the long-term effects of supplementation on thyroid health are still unknown. (chriskresser.com)
And we know that selenium is an essential component of the enzymes that convert T4 to T3, but whether supplementation will increase serum T3 levels is unclear. (chriskresser.com)
While it seems that selenium supplementation would be an obvious solution to poor thyroid function, long-term consumption of high doses of selenium can lead to complications such as gastrointestinal upsets, hair loss, white blotchy nails, garlic breath odor, fatigue, irritability, and mild nerve damage. (chriskresser.com)
2 ) It was a large clinical trial (with over 35,000 participants) that examined the relationship between baseline selenium status, supplementation with selenium and vitamin E (either together or separately), and future rates of prostate cancer in men over 55 years of age. (chriskresser.com)
60th percentile), selenium supplementation of 200 mcg/d increased the risk of high-grade prostate cancer by 62% when taken alone, and by 224% when taken with vitamin E. (chriskresser.com)
60th percentile), selenium supplementation of 200 mcg/d (either alone or with vitamin E) did not substantially increase or decrease the risk of prostate cancer. (chriskresser.com)
But if baseline levels are normal or high, supplementation may cause harm-as it appears to have done in this study. (chriskresser.com)
At least one study found that selenium supplementation produced these benefits even when selenium levels were normal at baseline. (chriskresser.com)
Therefore, a considerable number of studies have looked for alternative methods for the simultaneous supplementation of selenium and iodine in foodstuff. (muni.cz)
Evidence from 14 human studies, including clinical trials of selenium supplementation, case-control, cohort, and cross sectional studies on the association between selenium exposure and type-2 diabetes is conflicting. (dguv.de)
Brazil nuts are commonly used as a form of selenium supplementation, but it isn't commonly known that the level of selenium in Brazil nuts is highly variable. (zrtlab.com)
Organic and inorganic selenium supplementation to lactating mothers increase the blood and milk Se concentrations and Se intake by breast-fed infants. (deepdyve.com)
Selenium and vitamin E supplementation are unlikely to affect age-related cataract development in older men, according to an article published online September 18 in JAMA Ophthalmology . (medscape.com)
To our knowledge, the SEE study is the first randomized trial to assess the separate effect of selenium supplementation in cataract prevention," the researchers write. (medscape.com)

The effective form of selenium is L-selenomethionine, as this is the form most easily absorbed and stored in the body. (naturalnews.com)
When the yeast is grown in a selenium-enriched medium, it absorbs the selenium and converts it into the form of selenium naturally found in foods, selenomethionine. (openpr.com)
however, this form of selenium can cause cancer if ingested. (livescience.com)

10 wells were found to have selenium higher levels of selenium in the air. (cdc.gov)
Meats produced from animals that ate grains or plants found in selenium-rich soil have higher levels of selenium. (medlineplus.gov)
Now, the results showed that selenium supplements did not benefit men who had lower levels of the element at the start of the study, and nearly doubled the risk of prostate cancer in those who had higher levels of selenium (but still within ranges common among U.S. men). (livescience.com)
Our results support an increased risk of pancreatic cancer associated with higher levels of cadmium, arsenic, and lead, as well as an inverse association with higher levels of selenium and nickel. (medicalnewstoday.com)
Higher levels of selenium intake in the range of 200-300 µg/day are believed to be effective in the prevention of certain types of cancer such as lung, colon and prostate [7] [8] . (zrtlab.com)

Selenium deficiency produces biochemical changes that may predispose people who experience additional stresses to develop certain illnesses. (ion.ac.uk)
Keshan disease (congestive cardiomyopathy which historically occurred in parts of China) is an example, resulting from selenium deficiency and Coxsackievirus infection. (ion.ac.uk)
Rayman said: "Given the history of viral infections associated with selenium deficiency, we wondered whether the appearance of COVID-19 in China could possibly be linked to the belt of selenium deficiency that runs from the north-east to the south-west of the country. (ion.ac.uk)
September 2003 there is selenium deficiency. (cdc.gov)
There are thousands of articles that cement heavy research into selenium, such as a study of selenium deficiency related to cardiovascular disorders and inflammatory conditions. (vitalraadet.dk)
However, in the United States, selenium levels are typically much higher than they are in Holland, where deficiency is widespread. (chriskresser.com)
Furthermore, due to the strong relationship between iodine and selenium in metabolic processes, selenium deficiency often compromises the desired positive impact of salt iodization efforts. (muni.cz)
Selenium deficiency is not likely to be a concern in Canada, as the estimates from the Canadian TDS (2005-2011) show that the Canadian population meets the Institute of Medicine's recommended daily intake from food, which represents the main source of selenium. (canada.ca)
A research study at Lund University shows that there is an association between selenium deficiency and an increased risk of developing heart failure. (lu.se)
Since the 1960s, it has been known that chronic selenium deficiency leads to an aggressive type of heart failure, primarily affecting children and young people in areas with selenium-poor soil. (lu.se)
Already in 2019, our research group demonstrated that selenium deficiency is linked to a worsened prognosis in patients with established heart failure, says Martin Magnusson, cardiologist at Skåne University Hospital, adjunct professor at Lund University, and Clinical Fellow at the Wallenberg Center for Molecular Medicine. (lu.se)
In this current study, published in the journal Free Radical Biology and Medicine, the researchers observed that selenium deficiency is also associated with an increased risk of developing heart failure in individuals who do not have a known history of heart disease. (lu.se)
However, the researchers emphasize that they still do not know whether the selenium deficiency itself has this effect on the prognosis of heart failure or if it is the heart failure that affects selenium levels. (lu.se)

Selenium monochloride or diselenium dichloride is an inorganic compound with the formula Se2Cl2. (wikipedia.org)
Selenium can also be detected in the Ingestion of organic and inorganic forms absorbed through the gastrointestinal feces, hair, and nails. (cdc.gov)
Hydrogen diselenide, also known as (SeH)2, is an inorganic selenium compound with the chemical formula H2Se2. (qsstudy.com)
The key discovery occurred when Self found during an earlier study that the arthritis drug auranofin blocked selenoprotein synthesis ( Journal of Biological Inorganic Chemistry , May 2009, Vol. 14:4, pp. 507-519). (drbicuspid.com)
Evidence regarding inorganic selenium compounds is inadequate due to a lack of reliable studies. (dguv.de)
By itself, selenium and its inorganic compounds showed some genotoxic potential at high doses, but it is unclear if this activity is expressed at low levels to which humans may be exposed. (dguv.de)
Selenium cycling involves the transformation of inorganic species (Se0, SeII, SeIV, SeVI) in sediments and the water column to dimethylselenide and dimethyl diselenide by bacteria with the accumulation of organic Se species in plant detritus (selenomethionine) and animals (selenomethionine and selenocysteine). (edu.au)
Herein, ultrasound-assisted emulsification microextraction (USAEME) and dispersive liquid-liquid microextraction (DLLME) methods based on applying low-density organic solvents have been critically compared for the speciation of inorganic selenium, Se(IV) (selenite) and Se(VI) (selenate) in environmental water samples by gas chromatography-flame ionization detection (GC-FID). (who.int)
Total inorganic selenium was determined after the reduction of Se(VI) to Se(IV) and prior to the above procedures. (who.int)
The Se(VI) concentration was calculated as the difference between the measured total inorganic selenium and Se(IV) content. (who.int)
Both methods were successfully applied to the analysis of inorganic selenium in different environmental water samples and certified reference material (NIST SRM 1643e). (who.int)

This report studies the high-selenium yeast market, high selenium yeast is a form of supplemental selenium, which is also referred to as organic selenium. (openpr.com)
This experiment was conducted to determine the influences of adding organic selenium (Se) on growth properties, Se absorption and utilization, immunity and antioxidant activity in diets of Duroc weaning piglets. (scirp.org)
BioActive Selenium + Zinc contains the patented organic selenium yeast, SelenoPrecise, which has very good bioavailability. (selenium.ie)
Evidence from 65 human epidemiological studies on organic selenium compounds suggests an inverse association between selenium exposure and risk of several cancers, especially in men. (dguv.de)
These data do not provide evidence for any increase in cancer risk associated with intake of organic selenium compounds. (dguv.de)

Selenium (Se), an essential element and potent reproductive toxin, is enriched in parts of the San Francisco Estuary (SFE) to levels known to cause toxicity, yet the risk of Se to species that inhabit the SFE is not well understood. (usgs.gov)
Excess zinc is associated with gastrointestinal disturbances while chronic toxicity can lead to anaemia, neutropenia and bone abnormalities, whilst excess selenium is associated with nail-abnormalities, skin lesions and changes in peripheral nerves. (nutraingredients.com)
However, selenium toxicity is rare in the United States. (medlineplus.gov)
Selenium toxicity can result in hair loss, tremors, kidney failure, cardiac failure, neurological and gastrointestinal issues, respiratory distress and even death [6] [11] . (zrtlab.com)
The fate of selenium (Se) inputs from coal-fired power station operations in a marine dominated estuary, Lake Macquarie NSW, is explored, as well as Se toxicity, including sublethal and population effects. (edu.au)
Selenium toxicity generally occurs when exposure levels are much higher than the recommended daily intakes. (canada.ca)
Persistent selenosis symptoms were observed in five Chinese individuals with blood selenium concentrations ranging between 1054 and 1854 µg/L. The authors calculated that a blood selenium concentration of 1054 µg/L corresponded to an intake of 910 µg/day and identified these as the minimum blood selenium concentration and selenium intake causing toxicity, respectively. (canada.ca)
Further studies are needed to explore the possibility of mercury -induced ischemic stroke toxicity in other populations at higher exposure levels. (cdc.gov)

The basic theory of crystallography is introduced in Chapter 1, followed by a general discussion on pentafluorosulfuranyl (SF₅) containing heteroatom compounds and sulfur/selenium heterocycles in Chapter 2. (st-andrews.ac.uk)
Ten pentafluorosulfuranyl (SF₅)-containing aromatic compounds have been studied crystallographically in Chapter 3. (st-andrews.ac.uk)
selenium compounds can be absorbed detect recent exposures to high levels of Selenium is an essential element needed through the lungs. (cdc.gov)
The aim of this epidemiological and toxicological risk assessment of selenium and its compounds is to derive exposure riskrelationships (ERBs) if assessed to be carcinogenic or alternatively, an occupational exposure limit (AGW) based on the most sensitive endpoint, if assessed to be non-carcinogenic and ERBs cannot be derived. (dguv.de)
Selected studies were reviewed that investigated treatment with selenium compounds within the context of initiation-promotion experiments as well as some studies that studied their chemopreventative effects in animal models of different cancers. (dguv.de)
The ultimate mechanism of action of the effect of selenium on cancer development has not been established, but mechanistic studies indicate that both low-molecular weight selenium compounds as well as selenoproteins might be involved. (dguv.de)

However, cancer prevention remains one of the major benefits of selenium, and it is the only mineral that qualifies for a Food and Drug Administration (FDA)-approved qualified health claim for general cancer reduction incidence. (nutraingredients.com)
More studies on the benefits of selenium are needed. (medlineplus.gov)
The nutritional benefits of selenium were first discovered in a long-term trial on nutritional prevention of cancer that started in 1983. (naturalnews.com)

A while back I wrote an article on the role of selenium in autoimmune thyroid disease . (chriskresser.com)
While these studies provide some insight into biological effects of selenium that might affect glucose homeostasis, they are not sufficient to demonstrate a clear role of selenium in the development of frank diabetes. (dguv.de)
While many studies have investigated the possible association between selenium exposure and the endpoints of diabetes and cancer, no conclusions can be drawn regarding a causal role of selenium in those diseases. (dguv.de)

Brazil nuts are a very good source of selenium. (medlineplus.gov)
As a source of selenium, it may have limited utility in chemical synthesis or research. (qsstudy.com)
The source of selenium was mainly food (plant based) (Yang et al. (canada.ca)

Soil in Nebraska, South Dakota and North Dakota is especially rich in selenium, and people living in these areas typically have the highest dietary intake of selenium in the United States, according to the 2014 Harvard Health publication "The Truth About Vitamins and Minerals. (livescience.com)
Because of its uneven distribution in different geographical regions, the intake of selenium varies hugely worldwide. (dguv.de)
The authors also indicated that the maximum daily safe intake of selenium was 750-850 µg/day. (canada.ca)

Daily supplements of selenium may not reduce the risk of lung cancer, say results from a major trial that adds more questions to the cancer-fighting ability of the mineral. (nutraingredients.com)
In January 2009 the Journal of the American Medical Association (JAMA, 2009, Vol 301, pp. 39-51) reported the results the high profile Selenium and Vitamin E Cancer Prevention Trial (SELECT) which found no differences between daily supplements of selenium, vitamin E, both, or placebo with regards the rosk of prostate cancer. (nutraingredients.com)
A new study comparing the labelled and actual contents of zinc and selenium supplements, finds these products regularly contain less of the mineral than labelled, with some even falling outside the allowed labelling tolerances. (nutraingredients.com)
The Food Safety Authority of Ireland (FSAI) recently conducted a study to assess the safety of zinc and selenium containing supplements, as part of ongoing monitoring in this area. (nutraingredients.com)
Each of the 12 zinc and 10 selenium containing supplements were measured by Galway Public Analyst Laboratory between 1-3 times using accredited methods, in November 2021. (nutraingredients.com)
No selenium containing supplements in this study exceeded the selenium UL for any population group. (nutraingredients.com)
Sanecka summarised: "It is clear that some of the zinc supplements in this study were found to be non-conformant with the EU nutritional tolerances, but overall, most values for both nutrients were within the permitted nutrient tolerances, and did not exceed the UL. (nutraingredients.com)
She concluded with a number of recommendations: "This study highlights the importance of continuous monitoring by the FSAI to ensure the safety of food supplements on the Irish market. (nutraingredients.com)
Despite the importance of selenium, however, it is possible to take in too much - especially if taking supplements. (ion.ac.uk)
Recommended [selenium] intake (total, food + supplements) is 75 mcg/d for men and 60 mcg/d for women, or by the US RDA, 55 mcg/d. (ion.ac.uk)
What Are Selenium Supplements? (livescience.com)
Selenium supplements are popular, but do they work? (livescience.com)
Chinese government programs to supplement people's diets with selenium in the 1970s greatly reduced cases of Keshan disease, according to the National Institutes of Health's Office of Dietary Supplements. (livescience.com)
Low selenium levels are more common in people with certain conditions across the world, which has raised questions and hopes that selenium supplements could bring health benefits. (livescience.com)
Antioxidant supplements , including selenium, are often touted to help prevent to heart disease, cancer and vision loss. (livescience.com)
Selenium supplements in particular are purported to help people with asthma, and reduce the risk of rheumatoid arthritis and cardiovascular disease. (livescience.com)
Headaches, nausea and vertigo symptoms from intracranial pressure are said to be improved by selenium supplements. (livescience.com)
Keshan disease caused many childhood deaths in China until the link to selenium was discovered and supplements were given. (medlineplus.gov)
Men who take selenium and vitamin E supplements may increase their risk of prostate cancer, researchers have found. (livescience.com)
These men had previously participated in a large trial in 2001, in which they had been randomly assigned to take either high doses of vitamin E and selenium supplements , or a placebo. (livescience.com)
Researchers had measured the amount of selenium in the men's toenails before they started taking the supplements. (livescience.com)
The study is, in fact, a second look at a previous large, randomized trial, which aimed to investigate whether high doses of selenium and vitamin E supplements could lower a man's risk for prostate cancer, something that earlier studies had suggested. (livescience.com)
Previous studies have suggested that the effects of nutrition supplements depend on how well-nourished a population is. (livescience.com)
Read more news stories and studies on vitamins and supplements by going to SupplementsReport.com . (naturalnews.com)
The results of this study reinforce the long-standing view of Public Citizen's Health Research Group that there is little evidence that dietary supplements are either safe or effective. (citizen.org)
Because other foods, beverages, and supplements provide selenium on top of Brazil nuts, it is best to measure total daily selenium intake. (zrtlab.com)
Some foods and supplements have been studied more than others, and many studies are ongoing. (msdmanuals.com)
However, studies have not shown that taking supplements containing these antioxidants decreases the risk of cancer. (msdmanuals.com)
Some studies have found that higher vitamin D levels and calcium supplements may reduce the risk of precancerous polyps of the colon. (msdmanuals.com)

When investigating the difference between labelled and measured values, it was found that most zinc (86%) and selenium (78%) samples contained less of the nutrient than the labelled value, while fewer zinc (9.5%) and selenium (17%) samples contained more of the nutrient than the labelled value indicated. (nutraingredients.com)
No variation was found in one zinc and one selenium supplement. (nutraingredients.com)
The isotopes measured by this method include zinc (m/z 64), copper (m/z 65), and selenium (m/z 78) and the internal standard gallium (m/z 71). (cdc.gov)
The preparation was used was BioActive Selenium + Zinc from Pharma Nord. (selenium.ie)
Selenium + Zinc also contains zinc (which contributes to normal sperm cell production) and vitamins A, B6, C, and E. (selenium.ie)
You can read more about BioActive Selenium + Zinc and SelenoPrecise here . (selenium.ie)
Included in the study correlation of low zinc levels and active were 30 children in the age range 2-12 years pulmonary TB in adults [7,8]. (who.int)
11], there is no comprehensive study of zinc monary TB. (who.int)
This case-control study during 2003-04 compared serum zinc levels and other variables in 23 mothers of neonates affected with NTD and 36 mothers with normal healthy neonates in Dezyani hospital in Gorgan. (who.int)

Symptoms were not present in individuals with a blood selenium concentration of 1000 µg/L or below. (canada.ca)
Blood selenium levels in the range of 1000-2000 µg/L induced symptoms in up to 35% of individuals, whereas blood selenium concentrations in the range of 2000-3300 µg/L or higher induced symptoms in 45% of individuals. (canada.ca)
By 1992, their symptoms had disappeared, and their blood selenium concentrations had dropped from an average of 1346 µg/L to 968 µg/L, the latter representing a mean intake of 819 µg/day, which was identified as the NOAEL by the authors. (canada.ca)
After taking into account interindividual variations, the authors identified a safe maximum daily intake of 400 µg/day (corresponding to a blood selenium concentration of 0.559 mg/L). (canada.ca)
2012), also performed in areas with high levels of selenium, confirm the findings from the studies by Yang and colleagues, as selenosis symptoms were not observed at exposure levels up to 724 µg/day and blood selenium concentrations up to 1500 µg/L, respectively. (canada.ca)
A new study, published in The American Journal of Clinical Nutrition , shows that the highest levels of blood selenium or of selenoprotein P, the protein that distributes selenium from the liver around the body, are associated with a decreased risk of developing liver cancer (particularly hepatocellular carcinoma), even when all other major liver cancer risk factors are taken into account. (who.int)

Early routes to diselenium dichloride involved chlorination of elemental selenium. (wikipedia.org)
Tests for selenium in blood and urine are to low environmental levels of selenium elemental selenium dusts and other the most common methods used to daily through food, water, and air. (cdc.gov)
elemental selenium or selenium dioxide black hexagonal crystals. (cdc.gov)
This form is in the air can induce respiratory tract often referred to as elemental selenium or Oral (mouth) - Primary route of irritation, bronchitis, difficulty breathing, selenium dust. (cdc.gov)
At room temperature, hydrogen diselenide easily dissociates to hydrogen selenide (H2Se) and elemental selenium, making it unstable. (qsstudy.com)
Hydrogen diselenide can be prepared by the reaction of hydrogen gas (H2) with elemental selenium (Se) at elevated temperatures. (qsstudy.com)

Selenium is one of several nutrients known to have antioxidant properties, meaning selenium plays a part in chemical reactions that stop free radicals from damaging cells and DNA. (livescience.com)
Selenium helps your body make special proteins, called antioxidant enzymes. (medlineplus.gov)
Cambridge Heart Antioxidant Study (Stephens et al. (nationalacademies.org)
This was unexpected because both vitamin E and selenium have antioxidant roles and one could reasonably expect the opposite -- that supplemental vitamin E could compensate for an antioxidant deficit resulting from lower selenium, wrote Paul Frankel, a biostatistician at City of Hope Comprehensive Cancer Center, in an accompanying editorial. (livescience.com)
Selenium (Se) is an essential trace element for human and animal health, which has effects on anticancer, antioxidant, anti-cardiovascular diseases, strengthening antioxidant and immunity capacity, promoting growth and improving meat qualities, and so on [1] [2]. (scirp.org)
Plasma selenium, plasma glutathione peroxidase (a selenium-containing antioxidant) and whole blood glutathione peroxidase were measured. (zrtlab.com)
Brazil nuts, therefore, increase plasma selenium levels and antioxidant production in this human population. (zrtlab.com)
Nano-selenium enhances melon resistance to Podosphaera xanthii by enhancing the antioxidant capacity and promoting alterations in the polyamine, phenylpropanoid and hormone signaling pathways. (bvsalud.org)

Selenium is a trace element that occurs naturally in the soil and is absorbed by plants and crops, from where it enters the human food chain - either directly or through consumption of meat and other products from grazing animals. (nutraingredients.com)
Because selenium occurs naturally in the soil, organic crops will absorb it and transfer it into a form that is bioavailable to humans. (naturalnews.com)
The East Coast has selenium deficient soil, but the soil in the rest of the United States is rich in this mineral. (naturalnews.com)
Soil around the world varies in its selenium concentration. (livescience.com)
The higher the concentration of selenium in soil, the higher the concentration of selenium in crops. (livescience.com)
Soil in some areas of China and Russia is naturally low in selenium. (livescience.com)
areas with natural y high levels of Water www.atsdr.cdc.gov selenium in the soil. (cdc.gov)
How much selenium is in the vegetables you eat depends on how much of the mineral was in the soil where the plants grew. (medlineplus.gov)
Selenium is an essential element that is present in soil and enters the food chain through plants. (dguv.de)
Selenium content depends on the region in which the tree is grown, the pH of the soil, and can vary from nut to nut in a single batch or between trees [2] . (zrtlab.com)

Selenium has critical roles in reproduction, thyroid hormone metabolism, DNA synthesis, and protection from oxidative damage and infection. (ion.ac.uk)
It is a well-established fact that stannous salts prevent tooth decay and inhibit the growth of T. denticola , and this study demonstrated that stannous salts achieve this by impairing selenium metabolism, Self said. (drbicuspid.com)
This study provides evidence that the antimicrobial action of stannous salts and auranofin against T. denticola is mediated through inhibiting the metabolism of selenium for selenoprotein synthesis, the authors concluded. (drbicuspid.com)

According to findings presented at the American Society of Clinical Oncology 2010 Annual Meeting, a daily supplement of 200 micrograms of selenium was just as ineffective as placebo for reducing the risk of lung cancer recurrence or second primary malignancy. (nutraingredients.com)
Taking a selenium supplement in addition to food sources of selenium is not currently recommended for these conditions. (medlineplus.gov)
Selenium is found in meat, grains, seafood, and Brazil nuts, but one can also take it in supplement form. (selenium.ie)
Often, when doctors do a controlled trial and randomly give some people a seemingly helpful food or supplement, the studies do not show a beneficial effect. (msdmanuals.com)

Researchers concluded that selenium may protect against both goiter and thyroid disease. (naturalnews.com)
According to a team of international researchers, being deficient in selenium could negatively affect a patient's recovery from COVID-19. (ion.ac.uk)
Similarly, it is possible that the U.S. population is already getting adequately high levels of selenium through diet, and supplementing them with more selenium results in an unnaturally high amounts of the element, and has either no effect or increases cancer risk, the researchers said. (livescience.com)
The findings also point to a complex interaction between selenium and vitamin E, the researchers said. (livescience.com)
The trace mineral selenium could be the key to developing a new line of antibiotics for bacteria that cause periodontal disease, the researchers have discovered. (drbicuspid.com)
A study conducted by researchers at Erasmus Medical Center Rotterdam in The Netherlands found that healthy people who consumed the most vitamin K2 had 50 percent less calcium in their arteries. (naturalnews.com)
Researchers from University College, London, who studied 3,486 civil servants over five years, also came up with exactly the same figure: Mediterranean-style eaters were 30 per cent less likely to develop depression. (independent.co.uk)
Given that nails and toenails in particular are believed to be more reliable indicators of trace element levels compared with dietary assessment because of their ability to store intake/exposure from other sources over the long term, the researchers examined the study participants' toenails for 12 trace element levels. (medicalnewstoday.com)
The researchers used data from the prospective epidemiological heart failure study Malmö Preventive Medicine, which included 4,803 individuals (average age 70 years, of which 29.1 percent were women). (lu.se)
Researchers randomly assigned the SEE participants to receive vitamin E (n = 2844), selenium and vitamin E (n = 2789), selenium (n = 2805), or placebo (n = 2829). (medscape.com)
The limitation of the study she characterized is that the researchers did not distinguish among cataracts. (medscape.com)

Yet humans only need to eat a trace of selenium every day, about 55 micrograms or millionths of a gram. (livescience.com)
The doses used in that trial were 200 micrograms of selenium and 400 international units of vitamin E. These doses are higher than most multivitamins, which contain about 50 micrograms of selenium and 30 to 200 international units of vitamin E. (livescience.com)

Although selenium (Se) is considered as an anti-oxidant which may detoxify the effects, there are no data on whether Se could protect against the TL-shortening effects of heavy metals. (nih.gov)
Selenium has an anti-oxidant role. (nature.com)
The effects of methylmercury may be modified by selenium, which is an anti-oxidant that often co-exists with mercury in fish. (cdc.gov)

Baseline selenium status alone was not associated with prostate cancer risk. (chriskresser.com)

NewsTarget) Selenium is an essential trace mineral that forms an important part of our immune defense function, as well as a component in heart muscle. (naturalnews.com)
Selenium is an essential trace element. (medlineplus.gov)
Selenium is an essential trace nutrient mineral. (immunotec.com)
Selenium and iodine are essential trace elements for both humans and animals. (muni.cz)

A recent study in the Journal of the American Medical Association ( JAMA ) showed a 50 percent reduction in cancer deaths, including cancers of the lungs, colon and prostate. (naturalnews.com)
Previous studies showed selenium effective against prostate cancer in volunteers with a history of skin cancer. (naturalnews.com)
The new study examined about 1,700 men with prostate cancer and 3,100 healthy men. (livescience.com)
In addition, vitamin E more than doubled the risk of the most aggressive type of prostate cancer, but only among men with low selenium levels at the beginning of the study. (livescience.com)
It's worth pointing out that these findings contradict two previous (and considerably smaller) observational studies in the United States, which found that low toenail selenium status increases the risk of prostate cancer. (chriskresser.com)
3 , 4 ) In addition, a large Dutch study including over 58,000 participants found that those with the highest toenail selenium status had a 37% lower risk of prostate cancer than those with the lowest selenium status. (chriskresser.com)
While it's entirely possible that the very low selenium levels seen in Holland are associated with increased prostate cancer risk, there does not appear to be a correlation between selenium and prostate cancer in the United States-at least within the ranges of toenail selenium found in U.S. men over 55 years of age. (chriskresser.com)
In other malignancies, such as lung and prostate cancers, several agents have been studied, but no strategies have been proven effective. (medscape.com)
Cadmium is a known carcinogen and has been linked to an increased risk of lung, kidney, and prostate cancers , whilst high levels of selenium have been linked to offering protection against certain cancers. (medicalnewstoday.com)
In some men, taking high doses of vitamin E or selenium may double the risk of developing high-grade prostate cancer, according to a recent analysis. (consumerlab.com)
The SELECT was a 4-group, phase 3, randomized placebo-controlled trial of selenium , vitamin E, and a combination of selenium and vitamin E for the prevention of prostate cancer in 35,533 men, beginning in 2001. (medscape.com)
However, other studies suggest that a high calcium intake increases the risk of prostate cancer. (msdmanuals.com)
Interestingly, every prostate-cancer study with survival as the endpoint has found that most patients die of causes other than prostate cancer, mostly cardiovascular disease. (medscape.com)
In an interview study from the United Kingdom, Avery et al found that over half of men diagnosed with prostate cancer reported making dietary changes, primarily to promote general or prostate health or to facilitate coping. (medscape.com)

Those with lower selenium levels in the blood had a larger thyroid, which can be a sign of goiter or thyroid disease. (naturalnews.com)
Low selenium levels contribute to early miscarriage, thyroid disease , arthritis, and even viral infections. (naturalnews.com)
High blood levels of selenium have been shown to slow the replication of the HIV virus and those with low levels were 20 times more likely to die from AIDS than those with higher selenium levels. (naturalnews.com)
Studies have found that low levels of selenium could be linked with severity of COVID-19. (ion.ac.uk)
They found that in areas with high levels of selenium, people were more likely to recover from the virus. (ion.ac.uk)
The team reported that the COVID-19 cure rate was also significantly associated with selenium status (as measured by levels of selenium in hair) in 17 cities outside of Hubei. (ion.ac.uk)
Low selenium levels in China, Tibet and Siberia may play a role in a type of osteoarthritis called Kashin-Beck disease. (livescience.com)
Selenium levels drop with age, so some have claimed selenium can slow the aging process, cognitive decline and dementia. (livescience.com)
Low selenium levels are also implicated in depression, male infertility, weak immune systems and thyroid problems. (livescience.com)
Short-term exposure to high levels of Pure selenium exits as metallic grey to for selenium workers. (cdc.gov)
The study showed that vitamin E increased the cancer risk in men who had low levels of selenium. (livescience.com)
In fact, low levels of selenium can be significantly associated with a greater incidence of preterm births. (naturalnews.com)
Alcoholics, as well as patients with candidiasis, chronic fatigue syndrome, and ARC, have all shown low levels of selenium. (healthy.net)
In addition, heart disease and cancer are higher in people with diminished selenium levels. (healthy.net)
According to a study published online in Gut , high levels of the trace elements nickel and selenium in the body may lower the risk of developing the most common type of pancreatic cancer , whilst high levels of arsenic, lead, and cadmium could increase the risk of developing the disease. (medicalnewstoday.com)
Furthermore, those patients with the highest levels of nickel and selenium in their toenails were between 33% and 95% less likely to have the disease than those with the lowest levels. (medicalnewstoday.com)
If you are planning on supplementing with Brazil nuts, it is highly recommended that you test your urine selenium levels to determine if safe levels of selenium are being consumed. (zrtlab.com)
Healthy cholesterol levels are a fine balancing act as a new study has revealed both high and low levels can increase chances of an early death. (foodnavigator.com)
Moderate butter consumption could result in higher levels of both 'bad' LDL and 'good' HDL cholesterol, the findings of a Danish study suggest. (foodnavigator.com)
Since information on the endogenous Se levels of infant formulae is largely lacking, therefore there is still need for stricter quality control of the selenium content in infant formulae. (deepdyve.com)
Selenosis symptoms resulting from chronic exposure to high levels of selenium are characterized by hair loss, nail anomalies or loss, skin anomalies, garlic odour of the breath, tooth decay and, more severely, disturbances of the nervous system. (canada.ca)
The studies of Yang and colleagues focus on the symptoms of selenosis in a Chinese population (Enshi County) exposed to high levels of selenium (Yang et al. (canada.ca)
Yang and Zhou, 1994) have some limitations, they provide qualitative and quantitative information useful for the dose-response assessment and risk characterization of selenium associated with high levels of intake. (canada.ca)
The absence of symptoms in other populations with high dietary levels of selenium exposure is supportive of the use of the NOAEL identified by Yang and colleagues and the Institute of Medicine (Otten et al. (canada.ca)
Objectives: To examine the association between serum mercury levels with the incidence of ischemic stroke and to explore the possible effect modifications by serum selenium levels and demographic and geographic factors. (cdc.gov)
The risk is twice as high for individuals with low selenium levels. (lu.se)
The study shows an association between low selenium levels and an increased risk of developing heart failure over a follow-up period of 15 years. (lu.se)
The risk was twice as high in the 20 percent with the lowest selenium levels, says Amra Jujic, postdoctoral researcher at Lund University and the first author of the study. (lu.se)

Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer. (nutraingredients.com)
In 2003 a French study investigated the size of the thyroid gland compared to selenium consumption. (naturalnews.com)
This report studies the global market size of High Selenium Yeast (High-Selenium Yeast) in key regions like North America, Europe, Asia Pacific, Central & South America and Middle East & Africa, focuses on the consumption of High Selenium Yeast (High-Selenium Yeast) in these regions. (openpr.com)
Feed is the main application of high-selenium yeast, accounting for 92% of consumption share in 2016. (openpr.com)
Consumption of black garlic may improve endothelial function and lipid profile in subjects with high cholesterol resulting in lower cardiovascular risks, according to a recent study. (foodnavigator.com)
Although some older studies appeared to show a link between coffee consumption and cancer risk, more recent studies have not shown any connection. (msdmanuals.com)

Green leafy vegetables and several herbs, such as American and Siberian Ginseng, have bio-available forms of selenium. (healthy.net)

however, the amount of selenium is highly variable. (zrtlab.com)
Around 50-70% of selenium ingested is excreted in urine, therefore the amount of selenium in urine is proportional to the amount ingested [13] [14] . (zrtlab.com)

Plant foods, such as vegetables, are the most common food sources of selenium. (medlineplus.gov)
Brewer's yeast, wheat germ, and enriched breads are also good sources of selenium. (medlineplus.gov)

An article in the medical journal Lancet (July 15, 2000) also commented on the importance of selenium to thyroid health, as well as fertility problems and heart disease. (naturalnews.com)

Brazil nuts are well known for their high concentration of selenium. (zrtlab.com)

Selenium and sulfur are chemically very similar, so plants take up selenium in place of sulfur, forming the amino acids selenomethionine and selenocysteine. (zrtlab.com)
In a New Zealand study, 59 adults were separated into three groups, receiving either Brazil nuts (2 nuts a day or an estimated 100 µg selenium/day), selenomethionine tablets (100 µg selenium/day), or placebo tablets (no selenium) for 3 months [12] . (zrtlab.com)

An improved method involves the reaction of a mixture of selenium, selenium dioxide, and hydrochloric acid: 3 Se + SeO2 + 4 HCl → 2 Se2Cl2 + 2 H2O A dense layer of diselenium dichloride settles from the reaction mixture, which can be purified by dissolving it in fuming sulfuric acid and reprecipitating it with hydrochloric acid. (wikipedia.org)
In numerous studies, sodium selenite, selenate, selenide, and selenium dioxide have been shown to inhibit the genotoxicity of mutagens. (dguv.de)

The immune system relies on adequate dietary selenium intake and this nutrient exerts its biological effects mostly through its incorporation into selenoproteins. (mdpi.com)
The development of high-throughput omic approaches and novel bioinformatics tools has led to new insights regarding the effects of selenium and selenoproteins in human immuno-biology. (mdpi.com)
Scientists now know selenium is necessary in the body's production of selenoproteins, a family of proteins that contain selenium in the form of an amino acid. (livescience.com)
Selenium is found in a number of proteins in bacterial cells and human cells called selenoproteins. (drbicuspid.com)
Mode of action studies reviewed suggest that a U-shaped association between selenoproteins and type-2 diabetes risk might explain some of the apparently contradictory findings in the epidemiology studies. (dguv.de)
Among other factors, polymorphisms in genes encoding for selenoproteins may contribute to the inconsistencies observed in human studies. (dguv.de)
Selenium is a trace essential element that is incorporated into selenoproteins. (zrtlab.com)

No one has ever tried this approach, and it could potentially be a source for new narrow-spectrum antibiotics that block bacteria that require selenium to grow. (drbicuspid.com)
We have established the proof of principle that by blocking the bioavailability of selenium, the growth of microbes that require selenium can be inhibited," said Self in an interview with DrBicuspid.com . (drbicuspid.com)

The geometric mean concentration of concentrations ranging from 0.050 to Atlanta, GA 30333 selenium in serum from U.S. residents of 0.339 mg/L. (cdc.gov)
Serum mercury concentration and the risk of ischemic stroke: The REasons for Geographic and Racial Differences in Stroke Trace Element study. (cdc.gov)

has been applied for all cases according to There are studies that have revealed the the WHO since 1991. (who.int)

On the other hand, several studies indicate that supplementing with selenium has several benefits for people with autoimmune thyroid disease, including reduced inflammation and damage to thyroid tissue. (chriskresser.com)
In addition, studies by the National Toxicology Program showed that rodents developed liver and thyroid tumors after being given a ginkgo extract for up to 2 years. (cdc.gov)

Selenium is eliminated primarily in the Selenium was detected in concentrations urine and feces. (cdc.gov)
When undertaking risk assessments of Se, careful consideration should be given to understanding the fate of Se inputs and remobilisation into food webs as not all systems act in accordance with published studies that generally have high Se concentrations in the water column and phytoplankton-based food webs. (edu.au)

Selenium is one of the "essential" nutrients for humans, meaning that our bodies cannot make it, and so we have to get it from our diet. (livescience.com)
Plants pick up trace minerals that are in the dirt - including selenium - and convert it into a form that is consumable and useable to humans and other animals," said Dr. Stephen Neabore, a primary care doctor at the Barnard Medical Center in Washington, D.C. "Because it's found naturally in plants, generally if you're eating a varied diet you are going to get all the nutrients and minerals you need. (livescience.com)
Dosages for selenium, as well as other nutrients, are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board at the National Academies of Sciences, Engineering, and Medicine. (medlineplus.gov)

The study was stopped prematurely when an interim analysis revealed no general benefits, and a slightly higher progression-free survival in the placebo group compared with the selenium group. (nutraingredients.com)
The study showed a "significant reduction in total cancer mortality": 29 deaths compared to 57 in the placebo group. (naturalnews.com)
165 received 200µg Selenium + 200mg Q10 daily, and 161 received placebo. (vitalraadet.dk)
A new study suggests that high-dose vitamin E can help people with Alzheimer's disease retain their ability to perform activities of daily living (such as dressing) for several months longer than those given placebo, reducing caregiver time. (consumerlab.com)

Selenium dichloride degrades to diselenium dichloride after a few minutes at room temperature: 3 SeCl2 → Se2Cl2 + SeCl4 Diselenium dichloride is an electrophilic selenizing agent, and thus it reacts with simple alkenes to give bis(β-chloroalkyl)selenide and bis(chloroalkyl)selenium dichloride. (wikipedia.org)
selenium may occur to people living in of selenide. (cdc.gov)

The available studies were inadequate to address a potential cancer risk in humans under occupational conditions. (dguv.de)
Selenium has been classified by the International Agency for Research on Cancer in Group 3: not classifiable as to its carcinogenicity to humans (IARC, 1975). (canada.ca)
No studies in humans show an increased risk of cancer with the use of these sweeteners. (msdmanuals.com)
Laboratory studies in animal models provide important leads in designing, conducting, and interpreting large studies in humans, but translating data from animal studies to humans is often fraught with error. (medscape.com)
The principal message from nutritional studies in humans has been an endorsement of the benefits of a diet consisting mainly vegetables, fruits, grains, and fish, combined with restricted caloric intake and exercise. (medscape.com)

Market Research Hub (MRH) has actively included a new research study titled "Global High Selenium Yeast (High-Selenium Yeast) Market Insights, Forecast to 2025" to its wide online repository. (openpr.com)
This research report categorizes the global High Selenium Yeast (High-Selenium Yeast) market by players/brands, region, type and application. (openpr.com)
Selenium yeast is produced using the microorganism Saccharomyces cerevisiae, which is better known as bakers yeast or brewers yeast. (openpr.com)
In the past few years, high-selenium yeast industry maintained a rapid growth rate. (openpr.com)
In 2017, the global High Selenium Yeast (High-Selenium Yeast) market size was 290 million US$ and is forecast to 380 million US in 2025, growing at a CAGR of 3.2% from 2018. (openpr.com)
The objectives of this study are to define, segment, and project the size of the High Selenium Yeast (High-Selenium Yeast) market based on company, product type, application and key regions. (openpr.com)
The various contributors involved in the value chain of High Selenium Yeast (High-Selenium Yeast) include manufacturers, suppliers, distributors, intermediaries, and customers. (openpr.com)
To study and analyze the global High Selenium Yeast (High-Selenium Yeast) market size (value & volume) by company, key regions/countries, products and application, history data from 2013 to 2017, and forecast to 2025. (openpr.com)
To understand the structure of High Selenium Yeast (High-Selenium Yeast) market by identifying its various subsegments. (openpr.com)
Focuses on the key global High Selenium Yeast (High-Selenium Yeast) manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years. (openpr.com)
To analyze the High Selenium Yeast (High-Selenium Yeast) with respect to individual growth trends, future prospects, and their contribution to the total market. (openpr.com)

Earlier research suggests selenium may counter the harmful effects of arsenic, cadmium and lead. (medicalnewstoday.com)
He suggests that only randomized, carefully controlled studies can address these important issues. (medscape.com)

Selenium may reduce the risk of certain cancers. (nutraingredients.com)
Some studies in animals suggest that omega-3 fatty acids may stop cancers from growing or slow their growth. (msdmanuals.com)

Brazil nuts are very high in selenium (about 544 mcg per 28 g). (ion.ac.uk)
As mentioned above, it is based on Alehagen and colleagues' article from 2015, and it is evidence with a very high degree of reliability, as it was a double-blind, randomized, prospective study. (vitalraadet.dk)
A diet high in vegetables, fruits, fish, nuts, whole grains and olive oil could stave off depression, according to two separate studies conducted in Spain and London last month. (independent.co.uk)
National Toxicology Program (NTP) studies indicate that ingestion of high doses of selenium sulfide causes liver tumors in rats and mice, but no adequate inhalation studies exist. (dguv.de)
A recent study found that giving high-dose vitamin C or vitamin E to people involved in intensive exercise training blunted cellular changes thought to be important for improving muscular endurance. (consumerlab.com)
Why Are Brazil Nuts High in Selenium? (zrtlab.com)
1983). The level of intake was classified as low, medium or high and estimated through questionnaire distribution and measurements of selenium in food items. (canada.ca)
The results of this study showed evidence of an association between high cariogenic risk and great severity of oral disease in the studied group of young women and low calcium intake. (medscape.com)
The most convincing evidence is from studies that show diets low in fiber and high in processed meats increase cancer risk. (msdmanuals.com)
Some studies report that a diet high in fiber reduces the risk of cancer, especially colorectal cancer, but these reports controversial. (msdmanuals.com)

Conclusion: This study does not support an association between mercury and the incidence of ischemic stroke within a population with low-to-moderate level of exposure. (cdc.gov)
They then compared cataract incidence among the selenium vs no-selenium groups and the vitamin E vs no-vitamin E groups. (medscape.com)

1 ) Additionally, supplementing with selenium in the context of low iodine status may actually aggravate hypothyroidism. (chriskresser.com)
This paper reviews the most recent strategies in agriculture to fortify selenium and iodine in crop plants, their effect on the quality of the plant species used, and the potential impact of food processing on their stability in fortified crops. (muni.cz)

These observations and those of gel filtration studies of erythrocytes and plasma proteins reported elsewhere (Butler et al. (cambridge.org)

A second method for the synthesis involves the reaction of selenium with oleum and hydrochloric acid: 2 Se + 2 SO3 + 3 HCl → Se2Cl2 + SO2 + H2O + SO2(OH)Cl The crude diselenium dichloride is removed via separatory funnel. (wikipedia.org)
Selenium is a trace element that has a vital function in fertility, as it contributes to the synthesis of normal sperm cells. (selenium.ie)

Selenium also protects cells (sperm cells included) against oxidative damage. (selenium.ie)

Severe gastrointestinal disorders may affect the body's ability to absorb selenium. (medlineplus.gov)

Selenium by the body in smal amounts. (cdc.gov)
Small amounts of selenium are good for your health. (medlineplus.gov)
In Europe, even an average diet may not be able to provide sufficient amounts of selenium, according to food analyses. (selenium.ie)
However, selenium can be toxic in large amounts. (healthy.net)

These recommended daily intakes vary between 15 and 55 µg of selenium per day, depending on the age group. (canada.ca)

Many people with allergic reactions to these substances have found relief through the use of selenium. (healthy.net)

The Institute of Medicine's Food and Nutrition Board set a recommended dietary allowance of 55 µg selenium/day for adults with a tolerable upper intake level of 400 µg selenium/day [6] . (zrtlab.com)
Numerous studies in Europe (Ireland, Netherlands, United Kingdom, France) and in the United states suggest that the dietary factors in children may be as important as they are in adults. (medscape.com)
[ 9 ] In a recent study, severe tooth loss in older adults was found to be a key indicator of a compromised dietary quality. (medscape.com)
ABSTRACT This study aimed to evaluate the compliance of daily meals served to hypertensive and cardiac inpatients in Jordan according to WHO guidelines and the Therapeutic Lifestyle Changes (TLC) and Dietary Approach to Stop Hypertension (DASH) diets plans. (who.int)
RÉSUMÉ La présente étude visait à évaluer dans quelle mesure les repas quotidiens servis aux patients hospitalisés atteints d'hypertension ou de cardiopathie en Jordanie respectaient les recommendations de l'Organisation mondiale de la Santé (OMS) et les régimes alimentaires Therapeutic Lifestyle Changes (TLC) et Dietary Approach to Stop Hypertension (DASH). (who.int)
It is difficult to do a study like this because there are so many variables, and it's really hard to control for dietary factors and to actually get accurate reports," Shuchi Patel, MD, assistant professor of ophthalmology at Loyola Stritch School of Medicine in Maywood, Illinois, told Medscape Medical News . (medscape.com)

A study in older men in the U.S. found that taking large daily doses of vitamin E and/or selenium did not significantly reduce the risk of developing cataracts. (consumerlab.com)

Anatomy2

Diseases2

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes2

Technology, Industry, Agriculture3

Health Care1

Supplementation21

Form of selenium3

Higher levels of selenium5

Deficiency13

Inorganic11

Organic selenium5

Toxicity8

Compounds6

Benefits of selenium3

Role of selenium3

Source of selenium3

Intake of selenium3

Supplements29

Zinc9

Blood selenium6

Elemental selenium6

Antioxidant8

Soil10

Metabolism3

Supplement4

Researchers11

Micrograms2

Anti-oxidant3

Baseline selenium status1

Essential trace4

Prostate14

Levels28

Consumption6

Forms of selenium1

Amount of selenium2

Sources of selenium2

Importance of selenium1

Concentration of selenium1

Selenomethionine2

Dioxide2

Selenoproteins7

Require selenium2

Serum2

19911

Thyroid2

Concentrations2

Nutrients3

Placebo4

Selenide2

Humans5

Yeast11

Suggests2

Cancers2

High10

Incidence2

Iodine2

Proteins1

Synthesis2

Oxidative damage1

Body's1

Amounts4

Intakes1

Substances1

Dietary6

Significantly1