• Supplementation of Q10 and Selenium over a 4-year period could halve cardiovascular mortality. (vitalraadet.dk)
  • The article was an offshoot of the sensational article by researcher Dr. Urban Alehagen and colleagues from 2015 , who showed massive cardiovascular protection with supplementation of Q10 in combination with selenium. (vitalraadet.dk)
  • Men should avoid selenium or vitamin E supplementation at doses that exceed recommended dietary intakes," Dr. Eric Klein, chairman of the Glickman Urological and Kidney Institute at the Cleveland Clinic, and his colleagues wrote in their study, published today (Feb. 21) in the Journal of the National Cancer Institute. (livescience.com)
  • Given the risks and lacking evidence of benefits for other diseases, men older than 55 should avoid supplementation with either vitamin E or selenium at doses that exceed recommended dietary intakes, the researchers said. (livescience.com)
  • Early stage cancers were better halted, but age made no difference, as young and old alike benefited from selenium supplementation. (naturalnews.com)
  • The conclusion was that selenium supplementation did not protect against the development of further skin cancers, but it did preclude incidences of, and deaths from, other types of cancer. (naturalnews.com)
  • Selenium supplementation in people with Hashimoto's thyroiditis might reduce antibody levels and result in a decreased dosage of levothyroxine (LT 4 ) and may provide other beneficial effects (e.g. on mood and health-related quality of life). (karger.com)
  • The aim of our systematic review was to assess the effects of selenium supplementation on Hashimoto's thyroiditis. (karger.com)
  • In conclusion, the results of these four studies, assessed at unclear to high risk of bias, show that evidence to support or refute the efficacy of selenium supplementation in people with Hashimoto's thyroiditis is incomplete and not reliable to help inform clinical decision making. (karger.com)
  • Selenomethionine and sodium selenite are the two most common oral forms of selenium supplementation that are available in variable dosages (100 and 200 μg/day) [ 6,7 ]. (karger.com)
  • In a 12-week, randomized, double-blind, placebo-controlled clinical trial, 116 participants received daily supplementation with 500 mg of EpiCor or placebo for 12 weeks. (researchgate.net)
  • Brazil nuts are commonly used as a form of selenium supplementation, but it isn't commonly known that the level of selenium in Brazil nuts is highly variable. (zrtlab.com)
  • 3) The intervention was supplementation with probiotics, prebiotics or synthetics for the experimental group and placebo treatment for the control group. (researchsquare.com)
  • Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis. (druglib.com)
  • The effect of vitamin-mineral supplementation on juvenile delinquency among American schoolchildren: a randomized, double-blind placebo-controlled trial. (personalpowertraining.net)
  • The review of trials of selenium supplementation for preterm babies found that it reduces sepsis (blood infection). (cochrane.org)
  • Higher than usual levels of selenium supplementation may be beneficial, but more research is needed as most of the evidence comes from a country where selenium levels were unusually low. (cochrane.org)
  • To assess the benefits and harms of selenium supplementation in preterm or very low birth weight (VLBW) infants. (cochrane.org)
  • Randomised controlled trials which compared selenium supplementation either parenterally or enterally with placebo or nothing from soon after birth in preterm or VLBW infants and which reported clinical outcomes were considered for the review. (cochrane.org)
  • Supplementation with selenium was not associated with improved survival, a reduction in neonatal chronic lung disease or retinopathy of prematurity. (cochrane.org)
  • The largest clinical trial ever conducted on the use of dietary supplements to prevent cancer was the selenium and vitamin E supplementation randomized trial (SELECT). (medscape.com)
  • Current research suggests that selenium supplementation may be helpful in co-treating certain types of thyroid disorders. (myvillagegreen.com)
  • In this study, researchers evaluated the antioxidant effects of prolonged supplementation with coenzyme Q10 (CoQ10), selenium, and vitamins C and E on arterial elasticity, inflammatory, and metabolic measures in patients deemed as having multiple cardiovascular risk factors. (nutritionaloutlook.com)
  • Today, more and more experts call for selenium supplementation as a useful measure for improving global health. (pharmanord.com)
  • OBJECTIVE: This study was designed to assess the effects of selenium supplementation on CIMT and metabolic profiles of in diabetic hemodialysis (HD) patients. (bvsalud.org)
  • Selenium and vitamin E supplementation are unlikely to affect age-related cataract development in older men, according to an article published online September 18 in JAMA Ophthalmology . (medscape.com)
  • To our knowledge, the SEE study is the first randomized trial to assess the separate effect of selenium supplementation in cataract prevention," the researchers write. (medscape.com)
  • A double blind, randomized, placebo-controlled cancer prevention trial was published in 1997. (naturalnews.com)
  • A randomized placebo-controlled clinical trial of the effectiveness of thyroxine and triiodothyronine and short-term exposure to bright light in prevention of decrements in cognitive performance and mood during prolonged Antarctic residence. (druglib.com)
  • The randomized, placebo-controlled trial was performed over six months on 70 patients with at least two cardiovascular risk factors. (nutritionaloutlook.com)
  • The SELECT was a 4-group, phase 3, randomized placebo-controlled trial of selenium , vitamin E, and a combination of selenium and vitamin E for the prevention of prostate cancer in 35,533 men, beginning in 2001. (medscape.com)
  • Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials. (who.int)
  • Now, the results showed that selenium supplements did not benefit men who had lower levels of the element at the start of the study, and nearly doubled the risk of prostate cancer in those who had higher levels of selenium (but still within ranges common among U.S. men). (livescience.com)
  • Similarly, it is possible that the U.S. population is already getting adequately high levels of selenium through diet, and supplementing them with more selenium results in an unnaturally high amounts of the element, and has either no effect or increases cancer risk, the researchers said. (livescience.com)
  • The study showed that vitamin E increased the cancer risk in men who had low levels of selenium. (livescience.com)
  • High blood levels of selenium have been shown to slow the replication of the HIV virus and those with low levels were 20 times more likely to die from AIDS than those with higher selenium levels. (naturalnews.com)
  • Higher levels of selenium intake in the range of 200-300 µg/day are believed to be effective in the prevention of certain types of cancer such as lung, colon and prostate [7] [8] . (zrtlab.com)
  • If you are planning on supplementing with Brazil nuts, it is highly recommended that you test your urine selenium levels to determine if safe levels of selenium are being consumed. (zrtlab.com)
  • Pregnant women with low levels of selenium in the blood might have a higher chance of developing pre-eclampsia. (mymmunity.com)
  • This was unexpected because both vitamin E and selenium have antioxidant roles and one could reasonably expect the opposite -- that supplemental vitamin E could compensate for an antioxidant deficit resulting from lower selenium, wrote Paul Frankel, a biostatistician at City of Hope Comprehensive Cancer Center, in an accompanying editorial. (livescience.com)
  • Those with lower selenium levels in the blood had a larger thyroid, which can be a sign of goiter or thyroid disease. (naturalnews.com)
  • Babies are born with lower selenium concentrations in their blood than their mothers. (cochrane.org)
  • Patients with chronic inflammation typically have lower selenium status than those who are healthy. (interclinical.com.au)
  • Selenium is one of several nutrients known to have antioxidant properties, meaning selenium plays a part in chemical reactions that stop free radicals from damaging cells and DNA. (livescience.com)
  • Antioxidant supplements , including selenium, are often touted to help prevent to heart disease, cancer and vision loss. (livescience.com)
  • Patients were randomized to receive either selenium (SE), an antioxidant (as selenium selenite, 100 (g b.i.d), or pentoxifylline (PF), an anti-inflammatory and antifibrotic agent (6. (endocrine-abstracts.org)
  • Plasma selenium, plasma glutathione peroxidase (a selenium-containing antioxidant) and whole blood glutathione peroxidase were measured. (zrtlab.com)
  • Brazil nuts, therefore, increase plasma selenium levels and antioxidant production in this human population. (zrtlab.com)
  • Antioxidant compounds include certain vitamins - such as beta-carotene and vitamins A , C , and E - as well as compounds such as zinc , selenium , coenzyme Q10 , astaxanthin , lutein and zeaxanthin , lycopene , curcumin , and resveratrol . (consumerlab.com)
  • These researchers looked at clinical trials involving the common antioxidant vitamins beta carotene, vitamin A, vitamin C (ascorbic acid), vitamin E, and selenium either singly or in combinations. (abc.net.au)
  • The men used an antioxidant supplement or a placebo for between three and six months. (berkleycenter.com)
  • The rate was 15 percent in the antioxidant group and 24 percent in the placebo group. (berkleycenter.com)
  • According to the researchers, MOXI is the biggest placebo controlled, randomized trial to study the effects of antioxidant supplements on fertility in men without including assisted reproductive technology. (berkleycenter.com)
  • It is an absolutely vital component of the selenium-dependent proteins that have several biological functions in human health, including an antioxidant function. (pharmanord.com)
  • As an essential cofactor of the antioxidant enzyme glutathione peroxidase, selenium helps avert free radical damage and works with vitamin E. It supports normal growth, fertility, detoxification and the immune system. (mymmunity.com)
  • The doses used in that trial were 200 micrograms of selenium and 400 international units of vitamin E. These doses are higher than most multivitamins, which contain about 50 micrograms of selenium and 30 to 200 international units of vitamin E. (livescience.com)
  • Yet humans only need to eat a trace of selenium every day, about 55 micrograms or millionths of a gram. (livescience.com)
  • According to findings presented at the American Society of Clinical Oncology 2010 Annual Meeting, a daily supplement of 200 micrograms of selenium was just as ineffective as placebo for reducing the risk of lung cancer recurrence or second primary malignancy. (nutraingredients.com)
  • Be mindful, however, that according to the NIH, one ounce, or about 4 to 6 Brazil nuts contain approximately 544 micrograms of selenium, which is more than nine times the recommended daily allowance (RDA) of 55 mcg for most adults. (naturalhealth365.com)
  • The randomised, double masked placebo controlled trial recruited 633 children (age range one to four) in New Delhi, and assigned 316 kids to receive the fortified milk, containing iron (9.6 mg per day), selenium (4.2 micrograms), copper (0.27 mg), zinc (7.8 mg), and vitamins A (156 micrograms), C (40.2 mg) and E (7.5 mg). (bakeryandsnacks.com)
  • The study is, in fact, a second look at a previous large, randomized trial, which aimed to investigate whether high doses of selenium and vitamin E supplements could lower a man's risk for prostate cancer, something that earlier studies had suggested. (livescience.com)
  • Higher doses of selenium supplements may be able to reduce some complications for preterm babies, but more research is needed. (cochrane.org)
  • Supplemental doses of selenium for infants on parenteral nutrition higher than those currently recommended may be beneficial. (cochrane.org)
  • High doses of selenium can cause significant side effects including nausea, vomiting, nail changes, loss of energy, and irritability. (mymmunity.com)
  • Selenium supplements are popular, but do they work? (livescience.com)
  • Men who take selenium and vitamin E supplements may increase their risk of prostate cancer, researchers have found. (livescience.com)
  • These men had previously participated in a large trial in 2001, in which they had been randomly assigned to take either high doses of vitamin E and selenium supplements , or a placebo. (livescience.com)
  • Researchers had measured the amount of selenium in the men's toenails before they started taking the supplements. (livescience.com)
  • What Are Selenium Supplements? (livescience.com)
  • Chinese government programs to supplement people's diets with selenium in the 1970s greatly reduced cases of Keshan disease, according to the National Institutes of Health's Office of Dietary Supplements. (livescience.com)
  • Low selenium levels are more common in people with certain conditions across the world, which has raised questions and hopes that selenium supplements could bring health benefits. (livescience.com)
  • Selenium supplements in particular are purported to help people with asthma, and reduce the risk of rheumatoid arthritis and cardiovascular disease. (livescience.com)
  • Headaches, nausea and vertigo symptoms from intracranial pressure are said to be improved by selenium supplements. (livescience.com)
  • Because other foods, beverages, and supplements provide selenium on top of Brazil nuts, it is best to measure total daily selenium intake. (zrtlab.com)
  • Daily supplements of selenium may not reduce the risk of lung cancer, say results from a major trial that adds more questions to the cancer-fighting ability of the mineral. (nutraingredients.com)
  • In January 2009 the Journal of the American Medical Association ​ (JAMA, 2009, Vol 301, pp. 39-51) reported the results the high profile Selenium and Vitamin E Cancer Prevention Trial (SELECT) which found no differences between daily supplements of selenium, vitamin E, both, or placebo with regards the rosk of prostate cancer. (nutraingredients.com)
  • For Jane's hypothyroidism, the doctor prescribed natural thyroid hormones and also recommended that Jane begin taking iodine and selenium supplements. (betternutrition.com)
  • People with autoimmune diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and other should avoid taking selenium supplements. (mymmunity.com)
  • In a randomized, double-blind, placebo-controlled clinical trial over 8 weeks, 284 children on inhaled steroids were allocated to receive zinc supplements (50 mg/day) ( n = 144) or placebo ( n = 140). (who.int)
  • Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors, and inflammatory markers in patients with multiple cardiovascular risk factors," Nutrition & Metabolism , vol. 7, no. 55 (July 2010). (nutritionaloutlook.com)
  • One study at high risk of bias showed statistically significant improvement in subjective well-being with sodium selenite 200 μg plus titrated LT 4 compared with placebo plus titrated LT 4 (RR 4.67, 95% CI 1.61-13.50). (karger.com)
  • Selenium in the form of selenoproteins, is absorbed through active amino acid transport mechanisms and is more bioavailable than selenite or selenate. (interclinical.com.au)
  • However, it probably will not change clinical practices, because prescribing vitamin E and selenium for cataract "is definitely not mainstream," she said. (medscape.com)
  • Soil in Nebraska, South Dakota and North Dakota is especially rich in selenium, and people living in these areas typically have the highest dietary intake of selenium in the United States, according to the 2014 Harvard Health publication "The Truth About Vitamins and Minerals. (livescience.com)
  • Above and beyond the inadequacy of the dietary intake of selenium that results when people live in regions with selenium-poor soils and selenium-poor foods, there are groups of people who will need supplementary selenium regardless of where they live and grow or buy their food. (pharmanord.com)
  • however, the amount of selenium is highly variable. (zrtlab.com)
  • Around 50-70% of selenium ingested is excreted in urine, therefore the amount of selenium in urine is proportional to the amount ingested [13] [14] . (zrtlab.com)
  • Selenium disulfide should not be applied to damaged skin as there is a risk of systemic absorption and associated toxicity. (wikipedia.org)
  • The systemic absorption and toxicity of orally administered selenium sulfide has been studied in animals. (wikipedia.org)
  • Selenium toxicity can result in hair loss, tremors, kidney failure, cardiac failure, neurological and gastrointestinal issues, respiratory distress and even death [6] [11] . (zrtlab.com)
  • Taking doses above 400 mcg can increase the risk of developing selenium toxicity. (mymmunity.com)
  • In addition, vitamin E more than doubled the risk of the most aggressive type of prostate cancer, but only among men with low selenium levels at the beginning of the study. (livescience.com)
  • In fact, more users of vitamin E were getting prostate cancer than men who were on placebo. (livescience.com)
  • Previous studies showed selenium effective against prostate cancer in volunteers with a history of skin cancer. (naturalnews.com)
  • Prostate cancer, which is very common in older men, caused 63 percent fewer deaths among the selenium-takers. (harvardmagazine.com)
  • For example, results of the Prostate Cancer Prevention Trial (PCPT) garnered attention plus controversy regarding the use of finasteride daily versus placebo to reduce the risk of prostate cancer. (medscape.com)
  • However, the PCPT results also provided information that has not received adequate exposure and debate in the medical literature: Of the almost 19,000 men included in this randomized trial, 5 men died from prostate cancer in the finasteride and in the placebo arm, but 1123 men in total died. (medscape.com)
  • The Institute of Medicine's Food and Nutrition Board set a recommended dietary allowance of 55 µg selenium/day for adults with a tolerable upper intake level of 400 µg selenium/day [6] . (zrtlab.com)
  • Its prevalence is influenced by ethnicity, environmental factors, such as iodine and selenium status, age and gender [ 1,2 ]. (karger.com)
  • Even a moderate deficiency of selenium can have long term consequences since it may increase the risk of diseases associated with aging. (interclinical.com.au)
  • There is also evidence that suggests that deficiency of selenium may increase inflammatory lung damage caused during influenza virus infection. (mymmunity.com)
  • The most familiar ones are vitamin C , vitamin E , beta-carotene , and other related carotenoids, along with the minerals selenium and manganese. (harvard.edu)
  • The findings also point to a complex interaction between selenium and vitamin E, the researchers said. (livescience.com)
  • Researchers concluded that selenium may protect against both goiter and thyroid disease. (naturalnews.com)
  • Researchers in Arizona found that the group of volunteers who received a daily 200-microgram dose of selenium for four and a half years had a cancer death rate 50 percent lower than that of the group that received a placebo. (harvardmagazine.com)
  • The researchers were shocked to find 36 percent more lung cancers and 17 percent more lung-cancer deaths among those taking beta carotene and vitamin A than among those receiving a placebo. (harvardmagazine.com)
  • Researchers randomly assigned the men to receive a formulation containing a combination of the nutrients or the placebo. (berkleycenter.com)
  • Researchers randomly assigned the SEE participants to receive vitamin E (n = 2844), selenium and vitamin E (n = 2789), selenium (n = 2805), or placebo (n = 2829). (medscape.com)
  • These products included vitamins C, E, and D. They also featured nutrients such as lycopene, folic acid, selenium, zinc, and the amino acid derivative L-Carnitine. (berkleycenter.com)
  • However, excess intake is a rare problem in North America, since many people here rely on diets rich in processed foods and find it difficult to get enough selenium in the foods they eat. (myvillagegreen.com)
  • Unfortunately, people in many countries fail to get enough selenium to optimize their health. (pharmanord.com)
  • Materials and Methods: Sixty-six participants with NAFLD were allocated randomly to take either a placebo or one oral tablet of folic acid (1 mg) on a daily basis within eight weeks. (bvsalud.org)
  • Selenium is an essential trace element that is required for the correct functioning of the immune system with a recommended daily intake for adults of 55 μg [ 4 ]. (karger.com)
  • At the highest concentration, a single serving of Brazil nuts (around 6 whole nuts) could result in a selenium intake of 14515 µg, much higher than the recommended daily amount (RDA) of 55 µg [5] . (zrtlab.com)
  • Adverse effects of selenium intake are seen above 1500 µg/day, with "selenosis" and DNA damage occurring above 3000 µg/day [9] [10] . (zrtlab.com)
  • Due to the large variation of selenium in Brazil nuts, it is difficult to determine if Brazil nuts are providing inadequate, adequate, or excessive intake. (zrtlab.com)
  • Brazil nuts are a popular way to ensure you meet the recommended daily intake of selenium. (naturalhealth365.com)
  • Studies link low selenium intake with an increased risk of cancer and other problems. (pharmanord.com)
  • The data also exclude any large beneficial effect on cataract for long term supplemental use of selenium, with or without vitamin E, although a smaller but potentially important beneficial effect could not be ruled out. (medscape.com)
  • Selenium disulfide, also known as selenium sulfide, is a chemical compound and medication used to treat seborrheic dermatitis, dandruff, and pityriasis versicolor. (wikipedia.org)
  • Several scattered case reports of orange to red-brown scalp discoloration with selenium sulfide shampoo exist. (wikipedia.org)
  • There are thousands of articles that cement heavy research into selenium, such as a study of selenium deficiency related to cardiovascular disorders and inflammatory conditions. (vitalraadet.dk)
  • Gradually, it became clear that selenium plays an important role in normal inflammation and immune response, thyroid and reproductive function, liver reactions, protection against certain types of cancer, and cardiovascular health. (interclinical.com.au)
  • Further studies have shown the benefit of selenium in minimizing the risk of inflammatory diseases such as cardiovascular disease and asthma. (interclinical.com.au)
  • In his book "History of Selenium", Richard Morrill takes a closer look at some of the studies that link improved selenium status to lower cancer rates and fewer cardiovascular diseases. (pharmanord.com)
  • They looked only at well-designed studies ones that compared groups of people taking vitamins, single or in combinations with other vitamins and compared them to similar groups taking a placebo or taking nothing. (abc.net.au)
  • Because selenium occurs naturally in the soil, organic crops will absorb it and transfer it into a form that is bioavailable to humans. (naturalnews.com)
  • The East Coast has selenium deficient soil, but the soil in the rest of the United States is rich in this mineral. (naturalnews.com)
  • Soil around the world varies in its selenium concentration. (livescience.com)
  • Soil in some areas of China and Russia is naturally low in selenium. (livescience.com)
  • Selenium content depends on the region in which the tree is grown, the pH of the soil, and can vary from nut to nut in a single batch or between trees [2] . (zrtlab.com)
  • Selenium is a trace element that occurs naturally in the soil and is absorbed by plants and crops, from where it enters the human food chain - either directly or through consumption of meat and other products from grazing animals. (nutraingredients.com)
  • This is partly due to the fact that the agricultural soil in many parts of the world is low in selenium, and the problem is only made worse by unbalanced diets, veganism, and gluten intolerance (wheat is a selenium source). (pharmanord.com)
  • Large parts of Europe and the Middle East, Africa, Asia, and New Zealand are known to have low selenium concentrations in the soil and in the locally grown food. (pharmanord.com)
  • Similarly, large parts of certain regions of the United States - the Northeast, the Southeast, the Northwest, and the Southwest - have lower than average selenium concentrations in the soil and in the locally produced foodstuffs. (pharmanord.com)
  • White-muscle disease has been prevalent in animals, especially in ruminants, in regions in which the soil and the feedstuffs are lacking in selenium. (pharmanord.com)
  • A 2015 systematic review of topical treatments for seborrheic dermatitis of the scalp identified only a single randomized controlled trial evaluating selenium disulfide for the condition. (wikipedia.org)
  • It was a three-arm trial of 246 people with moderate to severe dandruff and compared treatment with 2% ketoconazole shampoo (n=97), 2.5% selenium disulfide shampoo (n=100), and placebo (shampoo base with no antiseborrheic agent) (n=49) for 29 days. (wikipedia.org)
  • A randomized controlled trial of 100 people who received selenium disulfide reported side effects of itching or burning sensation of the scalp (3 people), eruption near the hairline (1 person), psoriasis (1 person), lightening or bleaching of hair color (2 people), orange staining of the scalp (1 person), and a chemical taste while shampooing (1 person). (wikipedia.org)
  • Thirty-three New Zealand women aged 18-23 years received daily for 32 weeks, 200 μg Se as Seenriched yeast (selenomethionine), or brewer's yeast mixed with selenate, or no added Se (placebo) in a double-blind trial. (cambridge.org)
  • This study included 4447 French participants aged 45-60 y who were enrolled in the SU.VI.MAX study (1994-2002), which was a double-blind, placebo-controlled, randomized trial. (nih.gov)
  • Combined treatment with sertraline and liothyronine in major depression: a randomized, double-blind, placebo-controlled trial. (druglib.com)
  • Genistein aglycone does not affect thyroid function: results from a three-year, randomized, double-blind, placebo-controlled trial. (druglib.com)
  • The data are dominated by one large trial from a country with low selenium concentrations and may not be readily translated to other populations. (cochrane.org)
  • Two trials, including one trial with a much larger sample size than the others combined, were from geographical areas with low population selenium concentrations. (cochrane.org)
  • British Medical Journal ​ Online first, doi: 10.1136/bmj.39035.482396.55 "Effects of fortified milk on morbidity in young children in north India: community based, randomized, double masked placebo controlled trial" ​ Authors: S. Sazawal et al. (bakeryandsnacks.com)
  • This double-blind, placebo-controlled, randomized clinical trial was carried out at nine locations in the United States. (berkleycenter.com)
  • Forty patients with NAFLD were enrolled in a double-blind placebo-controlled trial to receive either one oral tablet of vitamin B12 (1000 µg cyanocobalamin) or a placebo per day for 12 weeks. (bvsalud.org)
  • MATERIALS AND METHODS: This randomized, double-blind, placebo-controlled trial was performed on 60 diabetic HD patients. (bvsalud.org)
  • William G. Christen, ScD, from the Division of Preventive Medicine and the Division of Medicine at Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, and colleagues conducted an ancillary study within the Selenium and Vitamin E Cancer Prevention Trial ( SELECT ) Eye Endpoints (SEE) Study. (medscape.com)
  • Selenium, an essential micronutrient for thyroid function, also boosts T4 to T3 conversion, protects the gland against damage, and plays a vital role in thyroid hormone synthesis. (naturalhealth365.com)
  • Selenium requires similar precautions as it can be toxic at high amounts. (naturalhealth365.com)
  • Selenium is a naturally occurring metalloid element that is essential to both humans and animal in trace amounts. (interclinical.com.au)
  • Pregnancy and breast-feeding: Selenium is POSSIBLY SAFE during pregnancy and breast-feeding when used short-term in amounts that are not above 400 mcg daily. (mymmunity.com)
  • Selenium has now been approved by the FDA for cancer reduction. (naturalnews.com)
  • The study showed a "significant reduction in total cancer mortality": 29 deaths compared to 57 in the placebo group. (naturalnews.com)
  • The study found a 73% reduction in dandruff score with ketoconazole, a 67% reduction with selenium disulfide, and a 45% reduction with placebo. (wikipedia.org)
  • However, cancer prevention remains one of the major benefits of selenium, and it is the only mineral that qualifies for a Food and Drug Administration (FDA)-approved qualified health claim for general cancer reduction incidence. (nutraingredients.com)
  • Supplementing very preterm infants with selenium is associated with benefit in terms of a reduction in one or more episodes of sepsis. (cochrane.org)
  • During 5.6 years of follow-up, 185 cataracts developed in the selenium groups and 204 in the no-selenium group, for a nonsignificant reduction of 9% for the selenium groups. (medscape.com)
  • Selenium deficiencies in the Keshan region in northeast China were severe enough to spur a form of heart disease called cardiomyopathy, now called Keshan's disease. (livescience.com)
  • Deficiencies in selenium can be detrimental to health, while selenium excess can be just as dangerous. (zrtlab.com)
  • Plants pick up trace minerals that are in the dirt - including selenium - and convert it into a form that is consumable and useable to humans and other animals," said Dr. Stephen Neabore, a primary care doctor at the Barnard Medical Center in Washington, D.C. "Because it's found naturally in plants, generally if you're eating a varied diet you are going to get all the nutrients and minerals you need. (livescience.com)
  • In 2003 a French study investigated the size of the thyroid gland compared to selenium consumption. (naturalnews.com)
  • Based on the study, the systematic review concluded that selenium disulfide may be effective in the treatment of dandruff but that the available evidence is limited and overall evidence quality is low. (wikipedia.org)
  • One study where patients with arteriosclerosis were either given vitamin E or a placebo. (marilynglenville.com)
  • In a single study, Brazil nut selenium concentration ranged from 0.03 to 512 µg/g, a substantial difference [4] . (zrtlab.com)
  • In a New Zealand study, 59 adults were separated into three groups, receiving either Brazil nuts (2 nuts a day or an estimated 100 µg selenium/day), selenomethionine tablets (100 µg selenium/day), or placebo tablets (no selenium) for 3 months [12] . (zrtlab.com)
  • The study was stopped prematurely when an interim analysis revealed no general benefits, and a slightly higher progression-free survival in the placebo group compared with the selenium group. (nutraingredients.com)
  • In a recent study, selenium was measured in patients suffering from IBD revealing that levels were significantly lower than in controls. (interclinical.com.au)
  • Selenium disulfide is sold as an antifungal agent in shampoos for the treatment of dandruff and seborrheic dermatitis associated in the scalp with fungi of genus Malassezia. (wikipedia.org)
  • However, the review did suggest use of over-the-counter selenium disulfide shampoos as an inexpensive option for managing mild symptoms of seborrheic dermatitis. (wikipedia.org)
  • Selenium is an essential trace element gained from nutrients. (cochrane.org)
  • There is preliminary experimental evidence that selenium inhibits reverse transcriptase and replication of human immunodeficiency virus (HIV). (mymmunity.com)
  • Incidences of cancer were reduced: only 77 people in the selenium group compared to 119 in the control. (naturalnews.com)
  • Men in the finasteride group had statistically significantly more erectile dysfunction, loss of libido, and gynecomastia than men in the placebo group. (cigna.com)
  • "Our results demonstrate that selenium is not an effective chemoprevention agent in an unselected group of lung cancer patients, and it's not something we can recommend to our patients to prevent a second cancer from developing or recurring," ​ said Karp. (nutraingredients.com)
  • First, participants in the zinc-selenium group saw a 9.2 percent increase in Free T3 hormone levels. (naturalhealth365.com)
  • There were 85 men in the treatment group and 86 in the placebo group. (berkleycenter.com)
  • The sperm shape, concentration, mobility, and DNA quality of those who received antioxidants were not statistically different from those of counterparts in the placebo group. (berkleycenter.com)
  • One group orally supplemented with two capsules per day containing 500 mg of vitamin C, 200 IU of vitamin E, 60 mg of CoQ10, and 100 mcg of selenium. (nutritionaloutlook.com)
  • However, these changes did not reach a significant level compared to the placebo group. (bvsalud.org)
  • Selenium may reduce the risk of certain cancers. (naturalnews.com)
  • Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer. (naturalnews.com)
  • Selenium and vitamin C didn't show any increased risk (and selenium actually seemed to lower the risk of death). (abc.net.au)
  • In very preterm babies, low selenium is associated with an increased risk of complications. (cochrane.org)
  • In very preterm infants low selenium concentrations have been associated with an increased risk of chronic neonatal lung disease and retinopathy of prematurity. (cochrane.org)
  • A yeast-based product (EpiCor, a dried Saccharomyces cerevisiae fermentate) was compared to placebo to determine effects on the incidence and duration of cold and flu-like symptoms in healthy subjects recently vaccinated for seasonal influenza. (researchgate.net)
  • Participants receiving the yeast-based product had significantly fewer symptoms and significantly shorter duration of symptoms when compared with subjects taking a placebo. (researchgate.net)
  • However, selenium is POSSIBLY UNSAFE when taken by mouth in high doses or for a long time. (mymmunity.com)
  • Selenium improves immunologic function by increasing the activity of interleukin-2 (IL-2) and promoting the normal growth and development of T helper cells. (mymmunity.com)
  • Blood selenium concentrations in newborns are lower than those of their mothers and lower still in preterm infants. (cochrane.org)
  • In experimental animals low selenium concentrations appear to increase susceptibility to oxidative lung disease. (cochrane.org)
  • Les cas comme les témoins présentaient des concentrations sériques en zinc initiales faibles [61,8 (E.T. 7,3) µg/dL et 60,9 (E.T. 4,3) µg/dL]. (who.int)
  • Selenium is one of the "essential" nutrients for humans, meaning that our bodies cannot make it, and so we have to get it from our diet. (livescience.com)
  • Selsun Blue is an over-the-counter shampoo for dandruff with 1% selenium disulfide as its active ingredient. (wikipedia.org)
  • Side effects of selenium disulfide shampoo for dandruff appear to be infrequent. (wikipedia.org)
  • Selenium disulfide acts as an antifungal and keratolytic agent to treat seborrheic dermatitis and dandruff. (wikipedia.org)
  • From 1994 to 2002, participants received daily vitamin C (120 mg), β-carotene (6 mg), vitamin E (30 mg), selenium (100 μg), and zinc (20 mg) in combination or as a placebo. (nih.gov)