Selectivity microelectrodes. Medical search. Frequent questions

Multiplexed detection of these two biomarkers yield about 90% sensitivity and selectivity that individual detection of cTnT and cTnI on separate microelectrode platform. (confex.com)
The methodcombines the spatial resolution of optical detection with the high sensitivity and selectivity of electrochemical recognition. (phys.org)
Calibration results showed the MEA probe had high sensitivity and good selectivity for DA. (uky.edu)
A research group has developed a neural device that detects specific neurotransmitters in the brain with high sensitivity and selectivity by combining multifunctional fibers and DNA molecular probes. (tohoku.ac.jp)
These defined aptamers sense neurochemicals with high sensitivity and high selectivity. (tohoku.ac.jp)
The nitrate- and phosphate-based microneedle electrochemical sensors had excellent selectivity and sensitivity, with a determined limit of detection (LOD) of 0.008 mM and 0.007 mM, respectively. (macewan.ca)
Accordingly, the solution is to merge various technologies into a single system that would employ the best available methods for the detection of specific water contaminants, so as to provide overall superior sensitivity, selectivity and long-term stability, while enabling real-time wireless data collection for enhanced cost-effectiveness. (ljmu.ac.uk)
Obtaining a limit of detection of 1.97 μM, sensitivity of 0.103 V log (μM) −1 of peak shift, and linear range of 10-150 μM, the effect of possible interfering species present in sweat is minimized, with no observable cross-reaction, thus maintaining a high degree of selectivity despite the absence of enzymes in the fabrication scheme. (tu-dresden.de)

Herein, we report an aptamer-based field effect transistor (aptaFET) biosensor, developed by using an extended gate field effect transistor with inter-digitated gold microelectrodes (IDμE) for the detection of the malaria biomarker Plasmodium falciparum glutamate dehydrogenase (PfGDH) in serum samples. (bath.ac.uk)
A flexible sensor is presented for electrochemical detection of ascorbic acid in sweat based on single-step modified gold microelectrodes. (tu-dresden.de)

In 1958, David Hubel and Torsten Wiesel discovered cells in the visual cortex that had orientation selectivity. (wikipedia.org)
They discovered this orientation selectivity when changing slides on the projector. (wikipedia.org)
The first possible advantage is that orientation selectivity may be intensified with lateral inhibition from neighboring cells of a slightly different preferred orientation. (wikipedia.org)
The third possible advantage is that if columns with similar orientation selectivity are close together, fewer afferents from the LGN are needed. (wikipedia.org)
So by removing a few LGN inputs and adding a few, the orientation selectivity can be changed marginally. (wikipedia.org)
We found 10.9% of V2 neurons exhibited robust orientation selectivity to MBs, and their responses correlated with monkeys' orientation-discrimination performances. (elifesciences.org)

Our approach involves the use of multiple microelectrodes arranged in compact arrays and moved simultaneously parallel to the cortical laminas. (jneurosci.org)
aspects of Pt electrical, mechanical, and biological performance remain as limiting factors which prevent the application of high-density microelectrode arrays for neural interfacing. (frontiersin.org)
We trained macaque monkeys to do orientation discrimination for motion boundaries (MBs) and recorded neuronal response in area V2 with microelectrode arrays. (elifesciences.org)
From electrode arrays implanted over areas V1 and V2, we recorded neural activity and examined (1) their selectivity to the orientation of MB, (2) their correlation with monkeys' behavioral choice, and (3) neuronal couplings between DS neurons and MB neurons. (elifesciences.org)
A theoretical approach to the steady-state limiting current response behavior of multiple microelectrode arrays, consisting of spherical, hemispherical, disk-shaped, or hemicylindrical electrode units, is presented. (keyopinionleaders.com)
An approximative treatment is given for realistic arrays that contain microelectrodes of finite size and a rigorous description is offered for hypothetical arrays of point or line electrodes. (keyopinionleaders.com)
The trend in neural recording interfaces toward employing high-channel-count probes or 2D microelectrodes arrays with densely spaced recording sites for recording large neuronal populations makes it harder to save on resources. (csic.es)

We have established previously that the density of ZnO nanostructure on microelectrode platform can be effectively controlled by varying precursor concentration, which in turn modulates the electrode behavior (micro/ nanoelectrode). (confex.com)
Dopamine sensing, increased channel count, and reduced electrode size for higher spatial selectivity are enabled by glassy carbon microelectrodes within a polyimide thin-film-silicone rubber hybrid assembly. (uni-freiburg.de)
Measurements of carbon nanotube aerosol at elevated electrode temperature showed improved selectivity to elemental carbon and compared well with the measurements from the thermal optical method (NIOSH Method 5040). (cdc.gov)
Moreover, the relationships, which exist between the thresholds of the electrical extracellular stimulation and the parameters including position of the electrode array and the spacing of the microelectrodes in array, are studied and obtained. (jpier.org)

Subsequent instrumentation of many distal nerves enabled direct measurement of the selectivity and peripheral targets of recruited neurons. (pitt.edu)
Recent advances in microelectrode array technology now permit a direct examination of the way populations of sensory neurons encode information about a limb's position in space. (utah.edu)
Dominance of end-stopped V1 neurons in the model leads to pattern selectivity in MT, while dominance of V1 cells with extra-classical RFs result in component selectivity. (edu.au)

Self-referencing recordings may be utilized to further improve the selectivity of the recordings. (uky.edu)
To improve the selectivity for carbon nanomaterial s, which mainly consist of elemental carbon (EC), the cathode was heated to 300 degrees C to reduce the contribution of organic carbon to the total atomic carbon. (cdc.gov)

Greater selectivity & micro. (science-products.ch)

Animal studies have shown the potential value of microstimulation with respect to increased stimulus selectivity. (nih.gov)

Traditional neuronal interfaces utilize metallic electrodes which in recent years have reached a plateau in terms of the ability to provide safe stimulation at high resolution or rather with high densities of microelectrodes with improved spatial selectivity. (frontiersin.org)
Optogenetics offers many advantages in terms of cell-type specificity, allowing to investigate functional connectivity between different brain areas at high spatial and neural population selectivity. (nih.gov)
Neuroscience research into how complex brain functions are implemented at an extra-cellular level requires in vivo neural recording interfaces, including microelectrodes and read-out circuitry, with increased observability and spatial resolution. (csic.es)

One means of accomplishing this is by microstimulation with microelectrodes implanted directly into neural tissue. (nih.gov)
A transient finite-element model has been presented to simulate extracellular potential stimulating in a neural tissue by a nonplanar microelectrode array (MEA). (jpier.org)

The selectivity and response time of these electrodes make them suitable for in vivo measurements in brain tissue. (uky.edu)
They were incorporated into solvent polymeric membranes, and the selectivity, slope of response, response time, emf repeatability, and the signal stability of the corresponding ion-selective electrodes (ISEs) were studied. (keyopinionleaders.com)
Finally the selectivity and dynamic range of epineural electrodes were characterized to demonstrate a path forward to clinical testing. (pitt.edu)

There has been growing interest in the development of electrochemical sensors for direct and real-time monitoring of NO. As the direct electrooxidation of NO requires a relatively high working potential, further surface modification with permselective membranes is required to achieve the desired selectivity for NO via size exclusion or electrostatic repulsion. (intechopen.com)
Scanning electrochemical microscopy (SECM) has been used to image electrochemical reactions by mechanically scanning a sample surface using a microelectrode. (phys.org)

The resulting l-lactate microelectrodes were linear to 20 mM (R 2 = 0.997 ± 0.001) and beyond in some cases with detection limits of 0.078 ± 0.013 mM (n = 12). (uky.edu)

The anion selectivity of the GABA-Cl channel was investigated, selectivity was determined using the reversal potential of the GABA event (E GABA ). (soton.ac.uk)

For this purpose, three all-solid-state Irgarol-selective microelectrodes based on PVC-type sensitive membrane were prepared using three different plasticizers and the novel ion-pair complex [Irgarol-H] + [Co(C 2 B 9 H 11 ) 2 ] − as the active site for selective irgarol recognition. (icmab.es)
The potentiometric coefficient of selectivity, K A,Bpot , shown that the Irgarol-selective microsensors were highly selective towards irgarol when compared to some possible interfering phytotoxins. (icmab.es)
Using standard orientation-selective V1 cells, end-stopped V1 cells, and V1 cells with extra-classical receptive fields (RFs) as inputs to MT, the model shows that the degree of pattern or component selectivity in MT could arise from the relative strengths of the three V1 input types. (edu.au)
We investigated the basolateral membranes, using double-barreled Ca 2+ or pH ion-selective microelectrodes. (cellphysiolbiochem.com)

amperometric sensors, biosensors, specifically-sensitive microelectrodes and lab-on-chip sensing systems. (ljmu.ac.uk)

During microelectrode experiments, it is normal to see penetrations where eye dominance changes between the contralateral eye and ipsilateral eye but this does not interrupt the orientation sequence. (wikipedia.org)
These columns have been investigated extensively by electrophysiological recording of neuronal responses along individual microelectrode penetrations. (jneurosci.org)

Direction selectivity of the retinotectal system of fish: Findings based on microelectrode extracellular recordings of the tectum opticum. (iitp.ru)

The AC/DC Differential Amplifier (AM3000H) with a headstage designed for use with glass pipette microelectrodes is also available. (adinstruments.com)
Low noise microelectrode array signal headstage pre-amplifier for in-vitro neuron culture. (upo.es)

These electrophysiological methods also allowed a direct investigation of neuronal selectivities that give rise to map features. (jneurosci.org)

A newly developed multisite array microelectrode for in vivo measurements of l-lactate is presented. (uky.edu)
Third, a layer of polyurethane is coated over the l-lactate oxidase to adjust the linear range of the microelectrode to one that is compatible with in vivo measurements. (uky.edu)
Preliminary in vivo measures of l-lactate in the brain of anesthetized rats support that the microelectrodes are capable of measuring rapid endogenous changes in vivo. (uky.edu)
In this paper, We described a low cost silicon based 16-site implantable microelectrode array (MEA) chip fabricated by standard lithography technology for in vivo test. (uky.edu)

Ion sensitive microelectrodes (ISMs) incorporating the ion exchanger Corning 477913, were used to measure intracellular Cl - concentration in the muscle bag cells. (soton.ac.uk)

They are typically composed of a linear array of microelectrodes integrated on a slender probe shafts combined with flat-cleaved optical fibers (FF) placed above the recording sites. (nih.gov)

Then, the effective lifetime of microelectrodes implanted in the DRG was characterized using recordings from the sciatic nerve. (pitt.edu)

High Pass, Low Pass, and Notch Filters offer wide frequency selectivity. (adinstruments.com)
The high selectivity of the biosensor for PfGDH was verified by testing relevant analogous human and parasitic proteins on the device. (bath.ac.uk)

Ortho-dimercury aromatic compounds were found to induce an adequate chloride-selectivity for physiological measurements. (keyopinionleaders.com)

In the future, dynamic selectivity could be combined with directed motion to develop building blocks for bottom-up fabrication in applications such as additive manufacturing and soft robotics. (nature.com)

The method involves microconcentration of aerosol on a microelectrode tip for subsequent analysis for atomic carbon using spark emission spectroscopy (SES). (cdc.gov)

This strategy enables the sensor's selectivity to be improved by incorporating the target molecule to the sensitive membrane. (icmab.es)

In terms of delivery, the freedom of active colloids to travel along individual pathlines constitutes a significant advantage vis-a-vis particles driven by externally controlled fields or gradients which move phoretically, i.e., migrating en-masse in an externally dictated direction 1 . (nature.com)

Specifically, the tangential organization of directional selectivity is characterized by slow continuous changes in directional preference, as well as lines (fractures) and points (singularities) that fragment continuous regions into patches. (jneurosci.org)

The cut-off point for permeation through these channels was found to be between the relative hydrated sizes of ClO 3 - and BrO 3 - , indicating a diameter for the selectivity filter of between 0.29 and 0.33nm. (soton.ac.uk)

Across any given microelectrode, spike amplitudes ranged from 70 to 300 μV peak to peak, with a mean signal-to-noise ratio of better than 5:1. (uky.edu)

We present a computational model of the visual pathway from primary visual cortex (V1) to MT that suggests an alternate model where the progression from component to pattern selectivity is not required. (edu.au)

Feasible explanations could be the unsatisfactory selectivity of NCX inhibitors and/or the dependence of the experimental model on the degree of Ca2+i overload. (unideb.hu)

Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. (broadinstitute.org)

In this process however, imaging speed is limited and the presence of the microelectrode itself may impinge on the sample and alter results. (phys.org)
The prevailing theory suggests that pattern selectivity results from the summation of the outputs of component cells as part of a hierarchical visual pathway. (edu.au)

The selectivity sequence of small anions was consistent with an Eisenman sequence 1, indicating that the selectivity determining region of the channel contained a low field strength site. (soton.ac.uk)

Anatomy40

Organisms20

Diseases1

Chemicals and Drugs78

Analytical, Diagnostic and Therapeutic Techniques and Equipment38

Psychiatry and Psychology2

Phenomena and Processes52

Disciplines and Occupations7

Technology, Industry, Agriculture8

Information Science4

Health Care1

Sensitivity8

Gold microelectrodes2

Orientation selectivity6

Arrays7

Electrode4

Neurons3

Improve the selectivity2

Greater Selectivity1

Stimulus selectivity1

Spatial3

Neural tissue2

Electrodes3

Electrochemical2

Detection1

Anion1

Selective4

Amperometric1

Penetrations2

Extracellular1

Headstage2

Electrophysiological1

Vivo4

Concentration1

Array1

Recordings1

High2

Measurements1

Fabrication1

Carbon1

Membrane1

Individual1

Specifically1

Found1

Signal1

Primary1

Model1

Effects1

Results2

Field1