AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and Occupations
IsoproterenolAdrenergic beta-AgonistsReceptors, Adrenergic, betaReceptors, Adrenergic, beta-2Receptors, Adrenergic, beta-1Cyclic AMPAdrenergic AgonistsIodocyanopindololAdenylate CyclaseReceptors, Adrenergic, beta-3PindololAdrenergic alpha-AgonistsPropranololAdrenergic beta-AntagonistsAdrenergic beta-3 Receptor AgonistsPropanolaminesColforsinReceptors, AdrenergicAdenosine A2 Receptor AgonistsCyclic AMP-Dependent Protein KinasesAlprenololNorepinephrineReceptor, Adenosine A3Adenosine A3 Receptor AgonistsAdrenergic beta-2 Receptor AgonistsReceptor, Adenosine A2APhenylephrineParotid GlandMyocardial ContractionAdrenergic alpha-2 Receptor AgonistsMyocardiumEpinephrinePurinergic P1 Receptor AgonistsAdenosine A1 Receptor AgonistsReceptors, Adrenergic, alpha-2Receptor, Adenosine A1Rats, Sprague-DawleyCells, CulturedAdenosine A3 Receptor AntagonistsAdenosineDose-Response Relationship, DrugAdrenergic beta-2 Receptor AntagonistsAdrenergic beta-1 Receptor AntagonistsFenoterolBucladesineGTP-Binding ProteinsMyocytes, CardiacPhenethylaminesCalciumSignal TransductionAdrenergic alpha-1 Receptor AgonistsReceptors, Purinergic P1EthanolaminesRats, WistarReceptors, Adenosine A2Heart VentriclesAdenosine A2 Receptor AntagonistsGuinea PigsDopamine AgonistsReceptor, Adenosine A2BKineticsTime FactorsRNA, MessengerCell LineHeartReceptors, Adrenergic, alpha-1Radioligand AssayPhosphorylationClonidineSerotonin 5-HT1 Receptor AgonistsGTP-Binding Protein alpha Subunits, GsAdrenergic AntagonistsCell MembraneSympathomimeticsEnzyme ActivationAdrenergic beta-3 Receptor AntagonistsAdrenergic alpha-2 Receptor AntagonistsAnimals, NewbornProcaterolAdrenergic alpha-AntagonistsAdenosine-5'-(N-ethylcarboxamide)AlbuterolGABA AgonistsMuscarinic AgonistsReceptors, AndrogenGTP-Binding Protein alpha Subunits, Gi-GoAdrenergic beta-1 Receptor AgonistsDihydroalprenololPurinergic P1 Receptor AntagonistsCHO CellsOxymetazolineCricetinaeAndrogen Receptor AntagonistsMuscle RelaxationXanthinesPrazosinMice, Inbred C57BLCardiotonic AgentsCholinergic AgonistsCarbachol
ReceptorsCellGPCRActivation
Receptors2
  • To understand better the cellular mechanisms of NE and its adrenergic receptors in the LA, we used antibodies directed against dopamine beta-hydroxylase (DβH), the synthetic enzyme for NE, or against two different isoforms of the beta-adrenergic receptors (βARs), one that predominately recognizes neurons (βAR 248) and the other astrocytes (βAR 404), to characterize the microenvironments of DβH and βAR. (frontiersin.org)
  • Appropriately we attemptedto demonstrate the experience of the receptors with the addition of the β1 agonist dobutamine to your ethnicities. (tech-strategy.org)
Cell2
  • By electron microscopy, βAR 248 was present in neuronal cell bodies, dendritic shafts and spines, and some axon terminals and astrocytes. (frontiersin.org)
  • βAR 404 was expressed predominately in astrocytic cell bodies and processes. (frontiersin.org)
GPCR1
  • Agonist binding promotes the formation of a GPCR-Gα(GDP)βγ complex. (elifesciences.org)
Activation1
  • Biased agonists are expected to have potential therapeutic benefits for various diseases due to their selective activation of favorable physiological responses or avoidance of the side effects of drugs. (biomedcentral.com)