Secretion of prolactin from pituitary. Medical search. Frequent questions

Additionally, the growth-hormone-releasing hormone (GH-RH) is a member of the VIP family and stimulates growth hormone secretion in the anterior pituitary gland. (wikipedia.org)
Production of prolactin takes place in the pituitary gland. (medicalnewstoday.com)
However, this condition is very rare and usually happens as a result of an underactive pituitary gland. (medicalnewstoday.com)
D-Aspartic acid acts as a signaling molecule in the neuroendocrine systems in the pituitary gland and the hypothalamus. (purebulk.com)
Tumors that grow from the pituitary gland can affect the whole body by interfering with normal hormone levels. (mayfieldclinic.com)
The pituitary gland is a small, bean-shaped organ that sits at the base of the brain, behind the bridge of the nose (Fig. 1 and 2). (mayfieldclinic.com)
The gland is connected to the hypothalamus in the brain by the pituitary stalk. (mayfieldclinic.com)
The pituitary gland is bordered on either side by the cavernous sinuses and below by the sphenoid sinus. (mayfieldclinic.com)
Directly above the pituitary gland is the optic chiasm, which is responsible for vision. (mayfieldclinic.com)
A cross-section of the pituitary gland (green) shows its relationship to the optic chiasm, the sphenoid sinus, and the cavernous sinuses on each side. (mayfieldclinic.com)
Side view of the pituitary gland sitting inside the bony sella. (mayfieldclinic.com)
The pituitary gland (green) is located deep within the skull in an area called the sella. (mayfieldclinic.com)
The pituitary gland is related to the optic chiasm above and the sphenoid sinus below. (mayfieldclinic.com)
Known as the master gland, the pituitary controls the other endocrine glands in the body. (mayfieldclinic.com)
A tumor that grows from the pituitary gland is called an adenoma. (mayfieldclinic.com)
These tumors may compress the normal pituitary gland decrease hormone production (hypopituitarism). (mayfieldclinic.com)
These grow from embryonic remnant cells in the pituitary gland. (mayfieldclinic.com)
Prolactinoma Prolactinomas are noncancerous tumors made up from lactotrophs in the pituitary gland. (merckmanuals.com)
The holocrine glands are endocrine glands that solely release hormones (e.g., thyroid, parathyroids, adrenals, pituitary gland). (vedantu.com)
This hormone is secreted by pituitary gland located in the brain. (tandurust.com)
A tumor in pituitary gland can cause increased production of prolactin hormone. (tandurust.com)
Released by the pituitary gland, prolactin takes center stage, acting as the maestro that directs mammary glands to commence lactation. (metsminorleagueblog.com)
The following explains why treatment with the Gamma Knife is the best choice for you with a residual or recurrent pituitary gland tumor. (gamma-knife.de)
The pituitary gland produces hormones and is located in the middle of the skull base. (gamma-knife.de)
An adenoma is a benign tumor - in this case affecting the pituitary gland. (gamma-knife.de)
A tumor can also impair the function of the pituitary gland itself. (gamma-knife.de)
Pituitary is and endocrine gland located within the sella turcica, residing inside the skull. (howmed.net)
The test may also be used to: investigate testicular dysfunction or erectile dysfunction rule out problems with the pituitary gland or hypothalamus Prolactin is a hormone released by the pituitary gland. (netlify.app)
2021-04-02 · Prolactin is a hormone released by the pituitary gland. (netlify.app)
Prolactin is a specific type of hormone that is produced by the Pituitary gland. (netlify.app)
A prolactin test measures the level of the hormone prolactin, which is made by the pituitary gland, in your blood. (netlify.app)
Normally, prolactin secretion by the pituitary gland. (netlify.app)
The pituitary gland is a pea-sized endocrine gland that sits at the base of the brain. (medscape.com)
Often referred to as the "master gland", the pituitary gland synthesizes and releases various hormones that affect several organs throughout the body (see the images below). (medscape.com)
The pituitary gland is entirely ectodermal in origin but is composed of 2 functionally distinct structures that differ in embryologic development and anatomy: the adenohypophysis (anterior pituitary) and the neurohypophysis (posterior pituitary). (medscape.com)
Development of pituitary gland. (medscape.com)
The fully developed pituitary gland (see the image below) is pea-sized and weighs approximately 0.5 g. (medscape.com)
Pituitary gland, sagittal section. (medscape.com)
The pituitary gland is enveloped by dura and sits within the sella turcica of the sphenoid bone. (medscape.com)
Immunoglobulin superfamily, member 1 (IGSF1) is a transmembrane glycoprotein highly expressed in the mammalian pituitary gland. (medscape.com)

Linkage to aryl hydrocarbon-interacting protein gene (AIP) mutation has been identified in some families with prolactinoma and in childhood-onset pituitary adenomas. (medscape.com)
Parlodel treatment is indicated in patients with prolactin-secreting adenomas , which may be the basic underlying endocrinopathy contributing to the above clinical presentations. (rxlist.com)
There are various kinds of pituitary tumors: adenomas, craniopharyngiomas, and Rathke's cleft cysts. (mayfieldclinic.com)
Closely related to pituitary adenomas are craniopharyngiomas and Rathke's cleft cysts. (mayfieldclinic.com)
Craniopharyngiomas typically grow from the pituitary stalk upward into the third ventricle and cause symptoms similar to pituitary adenomas. (mayfieldclinic.com)
Of hormonally active adenomas, about 50% secrete prolactin, 20% secrete growth hormone, 20% secrete adrenocorticotropic hormone, and 10% secrete multiple hormones. (mayfieldclinic.com)
Most pituitary tumors are adenomas. (merckmanuals.com)
Most tumors of the pituitary and suprasellar region are pituitary adenomas. (merckmanuals.com)
It makes up about 30% of all pituitary adenomas. (medlineplus.gov)
Untreated pituitary adenomas always have a small risk of suddenly getting bigger, most commonly from bleeding inside the tumor. (medlineplus.gov)
70% of these are hormone inactive pituitary adenomas and around 30% produce their own hormones, known as hormone active pituitary adenomas. (gamma-knife.de)
In all other cases, an endocrinologist diagnoses and treats pituitary adenomas wherever possible. (gamma-knife.de)
We therefore hypothesized that the physiological IGF-I-GH negative feedback loop may be reset in somatotroph adenomas, and we investigated the role of type 1 IGF receptor (IGF-R) and GH receptor (GHR) by quantifying mRNA expression in somatotroph tumours, and investigated the possible presence of mutations of the GHR gene.Methods: Pituitary t. (endocrine-abstracts.org)
Large corticotroph adenomas are uncommon pituitary mass lesions, representing around 10% of cases of Cushing's disease, and are often found to be locally invasive. (endocrine-abstracts.org)
Pregnant women have high 11 Feb 2013 Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels. (netlify.app)

After clinical evaluation a giant GH/TSH-secreting pituitary adenoma was diagnosed. (nih.gov)
This undifferentiated, monomorphous GH/TSH-secreting pituitary adenoma represents an entity that is unusual both in its ultrastructural features and clinical manifestations suggesting a cytogenesis from an early, undifferentiated stem cell. (nih.gov)
Headache may result from an enlarging pituitary adenoma, even when intracranial pressure is not increased. (merckmanuals.com)
Gigantism and Acromegaly Gigantism and acromegaly are syndromes of excessive secretion of growth hormone (hypersomatotropism) that are nearly always due to a pituitary adenoma. (merckmanuals.com)
Prolactinoma is the most common type of pituitary tumor (adenoma) that produces a hormone. (medlineplus.gov)
This will depend on whether there are still remnants following removal of a pituitary adenoma, or whether it is a recurrent tumor. (gamma-knife.de)
A pituitary adenoma may cause overproduction of certain hormones. (gamma-knife.de)
Even though the pituitary tumor has already been surgically removed, you are diagnosed with a recurrent tumor - meaning the pituitary adenoma has returned? (gamma-knife.de)
Following conventional surgery on a pituitary adenoma the patient must avoid any strenuous, physical activities for between 3 and 6 weeks. (gamma-knife.de)
We describe a patient with an unusual mass presentation of a pituitary adenoma in whom there was also a marked discrepancy between the clinical and laboratory findings in the assessment of suspected Cushing's d. (endocrine-abstracts.org)

Functioning pituitary tumors secrete high levels of hormones and interfere with other body organs. (mayfieldclinic.com)
Nonfunctioning pituitary tumors do not secrete hormones. (mayfieldclinic.com)
It produces neurohormones which regulate the synthesis and secretion of pituitary hormones. (vedantu.com)
This may also lead to acromegalia (uncontrolled secretion of growth hormones), Cushing syndrome (overproduction of cortisol), or prolactinoma (overproduction of prolactin). (gamma-knife.de)
Asymptomatic pituitary tumors that do not produce hormones or damage surrounding structures can be initially monitored. (gamma-knife.de)
How is the regulation of prolactin secretion different from other pituitary hormones? (sagepub.com)
Anterior pituitary consists of five different cell types producing six hormones. (howmed.net)
Anterior pituitary secretions are regulated by the hormones from hypothalamus , acting through the hypothalamic-hypophysial portal system. (howmed.net)
Hormones secreted by adenohypophysis (anterior pituitary). (medscape.com)
Hormones secreted by neurohypophysis (posterior pituitary). (medscape.com)
The adenohypophysis constitutes roughly 80% of the pituitary and manufactures an array of peptide hormones. (medscape.com)
The release of these pituitary hormones is mediated by hypothalamic neurohormones that are secreted from the median eminence (a site where axon terminals emanate from the hypothalamus) and that reach the adenohypophysis via a portal venous system. (medscape.com)
These hypothalamic cell bodies produce hormones that undergo axonal transport through the pituitary stalk and into terminal axons within the neurohypophysis. (medscape.com)
ABSTRACT To determine the effects of Ramadan fasting on the secretion of sex hormones in single healthy males, we measured blood hormone levels of testosterone, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in 52 single male students aged 18-24 years who were fasting for 12 hours during Ramadan. (who.int)
The main concern of this study was to determine the effects of Islamic fasting on Results the secretion of sex hormones in single healthy males. (who.int)

For example, a prolactinoma grows from prolactin-producing cells. (mayfieldclinic.com)
The most common pituitary tumor, a prolactinoma, causes an overproduction of the hormone that helps control sexual function. (mayfieldclinic.com)
A prolactinoma is a noncancerous (benign) pituitary tumor that produces a hormone called prolactin. (medlineplus.gov)
the clinical diagnosis of prolactinoma depends on the degree of hyperprolactinaemia in the context of pituitary tumour size. (endocrine-abstracts.org)

Prolactinomas, benign lesions that produce the hormone prolactin, are the most common hormone-secreting pituitary tumors. (medscape.com)
Both males and females produce the hormone prolactin, but it is known for telling the body to make breast milk when someone is pregnant or breastfeeding . (medicalnewstoday.com)
At the heart of milk production lies the hormone prolactin, the very essence of this remarkable symphony. (metsminorleagueblog.com)

Tumor formation is due to neoplastic transformation of anterior pituitary lactotrophs, resulting in excess synthesis and secretion of prolactin (PRL). (medscape.com)
The secretion of prolactin by the anterior pituitary is mainly under hypothalamic inhibitory control, likely exerted through release of dopamine by tuberoinfundibular neurons. (drugs.com)
Generalized Hypopituitarism Generalized hypopituitarism refers to endocrine deficiency syndromes due to partial or complete loss of anterior lobe pituitary function. (merckmanuals.com)
Adenohypophysis or anterior pituitary (develops from Rathke's pouch) b. (howmed.net)
A new procedure has been developed for dissociating anterior pituitary tissue and producing a viable suspension of single cells. (rupress.org)
In the vast majority of prolactin deficiency states, the deficiency occurs secondary to general anterior pituitary dysfunction. (medscape.com)
Because prolactin release is inversely related to dopamine levels in the anterior pituitary, critically ill patients on prolonged dopamine infusion have resultant prolactin deficiency. (medscape.com)
In association with other anterior pituitary dysfunction, prolactin deficiency is uncommon except with pituitary infarction (Sheehan syndrome). (medscape.com)
The sella turcica is a saddle-shaped depression that surrounds the inferior, anterior, and posterior aspects of the pituitary. (medscape.com)

Post-transcriptional protein synthesis by GH3 cloned pituitary cells, which secrete prolactin and growth hormone, is dependent on Ca2+. (aspetjournals.org)
Prolactin deficiency is characterized by the inability of pituitary lactotrophs to secrete prolactin and by the resulting lack of puerperal lactogenesis. (medscape.com)

It releases secretions into the bloodstream and provides feedback to the hypothalamus. (mayfieldclinic.com)
The hypothalamus then regulates pituitary hormone levels, depending on the needs of the body. (mayfieldclinic.com)
The paper describes the ways in which the dopamine pathways of the hypothalamus interact with prolactin secreted by the pituitary. (sagepub.com)
How does prolactin regulate dopamine production within the hypothalamus? (sagepub.com)
It is connected through the pituitary stalk with the hypothalamus. (howmed.net)
Neurohypophysis or posterior pituitary (neural tissue outgrowth from hypothalamus) c. (howmed.net)
The study indicates an effect of low toluene exposure on the hypothalamus-pituitary axis, with a secondary decrease in testosterone secretion. (lu.se)
The infundibulum pierces the diaphragma sellae in order to connect the pituitary to the hypothalamus. (medscape.com)

The level of prolactin starts increasing during the late pregnancy period and soon after child birth. (tandurust.com)
Prolactin test measures the level of prolactin in the blood and it can help determine the cause of abnormal milk production in a female who is not pregnant or breastfeeding, diagnose the cause of infertility in couples, and erectile dysfunction in men, it also helps to diagnose the cause of menstrual irregularities in women. (netlify.app)
The gender-related difference in tumor size and level of prolactin was confirmed in this analysis where men had a larger diameter and a higher baseline prolactin level. (bvsalud.org)

Results of in vitro studies demonstrate that cabergoline exerts a direct inhibitory effect on the secretion of prolactin by rat pituitary lactotrophs. (drugs.com)

Cabergoline decreased serum prolactin levels in reserpinized rats. (drugs.com)
cabergoline n=168), DOSTINEX produced a dose-related decrease in serum prolactin levels with prolactin normalized after 4 weeks of treatment in 29%, 76%, 74% and 95% of the patients receiving 0.125, 0.5, 0.75, and 1.0 mg twice weekly respectively. (drugs.com)
A meta-analysis of studies of the usefulness of raised serum prolactin in diagnosing generalised tonic-clonic seizures (GTCS) in patients presenting to the accident and emergency (A&E) department after a single episode of syncope. (bmj.com)
Serum prolactin should be measured in patients presenting to the A&E department within an hour of a syncopal episode, unless the cause is immediately obvious. (bmj.com)
Is a serum prolactin concentration useful in excluding a seizure disorder? (bmj.com)
In 1978 a raised serum prolactin concentration was found to be a useful marker of a generalised tonic clonic event if measured within an hour of the event. (bmj.com)
This study seeks to investigate the following: In patients presenting with syncope does a serum prolactin concentration of greater than three times the baseline accurately predict the occurrence of a GTCS? (bmj.com)
Serum prolactin levels that were suppressed by bromocriptine resulted in decreased spermatogenesis and decreased testosterone production in healthy male volunteers. (medscape.com)

High prolactin levels, or hyperprolactinemia, are more common and can have many causes. (medicalnewstoday.com)
If a person has high prolactin, depending on their levels, they may have an underlying condition that requires treatment. (medicalnewstoday.com)
The tumor is often detected at an earlier stage in young women than in men because the high prolactin causes irregular menstrual periods. (medlineplus.gov)

Posterior Pituitary- Oxytocin, Antidiuretic hormone. (vedantu.com)

Hyperprolactinemia: Prolactin elevations occur and persist during chronic administration. (nih.gov)
Treatment is indicated if mass effects from the pituitary tumor and/or significant effects from hyperprolactinemia are present. (medscape.com)
Parlodel (bromocriptine mesylate) is a dopamine receptor agonist used to treat certain conditions caused by a hormone imbalance in which there is too much prolactin in the blood (hyperprolactinemia), and to treat these disorders when they are caused by brain tumors that can produce prolactin. (rxlist.com)

To study how these metabolites influence parent drug pharmacodynamics, we administered BCT to rats intravenously (1 mg/kg i.v.) and orally (10 mg/kg p.o.) and measured the inhibition of prolactin secretion. (aspetjournals.org)
[ 9 ] In research using a mouse model, inhibition of prolactin release impaired lymphocyte function and depressed macrophage activation. (medscape.com)

Hyperprolactinaemia in the presence of pituitary tumour can occur from tumour secretion or from stalk compression causing loss of dopaminergic inhibition. (endocrine-abstracts.org)

MRIs (without contrast) reported pituitary macroadenoma with suprasellar extension but no optic chiasm compression. (endocrine-abstracts.org)

We found that monohydroxylated BCT was able to lower prolactin secretion like BCT. (aspetjournals.org)
Women had a lower prolactin level and a smaller tumor diameter at diagnosis but pituitary deficiencies were more frequent and outcome was worse. (bvsalud.org)

Its actions stimulate the secretion of gonadotropin-releasing hormone, growth hormone, luteinizing hormone, and prolactin. (purebulk.com)

Production of prolactin and growth hormone was decreased by secretory inhibitors to the same extent and with the same Ca2+ concentration dependence as was observed for inhibition of amino acid incorporation. (aspetjournals.org)
Circadian pattern of prolactin secretion in children with growth hormone deficiency and congenital organic lesions in the hypothalamic-pituitary region. (nel.edu)
Stawerska R, Lewiński A, Smyczyńska J, Hilczer M, Kowalska E, Kaniewska D, Karasek M. Circadian pattern of prolactin secretion in children with growth hormone deficiency and congenital organic lesions in the hypothalamic-pituitary region. (nel.edu)
Insulin-like growth factor-I (IGF-I) secretion is growth hormone (GH) dependent. (nel.edu)
Insulin suppresses growth hormone secretion by rat pituitary cells. (jci.org)
The effects of insulin on basal and hydrocortisone-induced growth hormone (GH) secretion were studied in rat pituitary tumor cells (GH3). (jci.org)
Although higher doses (13 nM) of insulin-like growth factor (IGF-I) also suppressed basal GH secretion, IGF-I did not alter the GH and PRL secretory changes induced by hydrocortisone. (jci.org)
They arise from pituitary cell types due to both cell cycle trophic dysruptions leading to adenomatous growth, as well as a coupling of specific hormone gene over-expression. (endocrine-abstracts.org)
Thus growth hormone is a diabetogenic hormone producing pituitary diabetes (due to overproduction of glucose and decreased utilization). (howmed.net)
Throughout this period, the cells incorporate linearly [ 3 H]leucine into protein for up to 4 h at a rate 90% greater than hemipituitaries, and they synthesize, transport intracellularly, and release the two major pituitary secretory products, growth hormone and prolactin. (rupress.org)
The tumor cells were not stained for prolactin, growth hormone and ACTH. (medassocthai.org)
Moreover, IGSF1 mutations are also commonly associated with other clinical phenotypes, including prolactin and growth hormone dysregulation, and macroorchidism. (medscape.com)

1000 ng/ml and no concomitant GH/ ACTH secretion. (bvsalud.org)

Melanocyte-stimulating hormone stimulates prolactin secretion through melanocortin 3-receptors expressed in mammotrophs in themouse pituitary. (elsevierpure.com)
it stimulates prolactin release in the domestic turkey. (wikipedia.org)
Endothelin-3 inhibits prolactin and stimulates LH, FSH and TSH secretion from pituitary cell culture. (yale.edu)

This can also occur due to a rare but serious postpartum complication doctors call Sheehan syndrome, which results in pituitary insufficiency. (medicalnewstoday.com)

This is called pituitary apoplexy, and it is a medical emergency. (medlineplus.gov)
Most people with pituitary apoplexy describe it as having the worst headache of their life. (medlineplus.gov)
Pituitary apoplexy is a rare condition caused by haemorrhage or infarction into a pituitary tumour. (endocrine-abstracts.org)

Specific symptoms affecting males can indicate a problem with prolactin. (medicalnewstoday.com)
Based on the person's symptoms, a doctor will usually order a prolactin test if they suspect a problem with the hormone. (medicalnewstoday.com)
When pituitary tumors grow they can compress the above-mentioned structures and cause symptoms. (mayfieldclinic.com)
Pituitary Lesions Patients with hypothalamic-pituitary lesions generally present with some combination of Symptoms and signs of a mass lesion: headaches, altered appetite, thirst, visual field defects-particularly. (merckmanuals.com)

Partial isolated prolactin deficiency is rare, and case reports of total isolated prolactin deficiency are rarer still and may have a genetic component (ie, familial puerperal alactogenesis). (medscape.com)
A partial prolactin deficiency may result in inadequate lactation. (medscape.com)
Pituitary deficiency was present in 91% of cases, with hypogonadotropic hypogonadism being the most frequent. (bvsalud.org)
Investigations in two IGSF1 knockout mouse models converged to show that IGSF1 deficiency leads to reduced expression of the receptor for thyrotropin-releasing hormone (TRH) and impaired TRH stimulation of thyrotropin secretion, providing a candidate mechanism for the central hypothyroidism observed in patients. (medscape.com)

Prolactin inhibitory hormone (PIF), inhibiting the release of prolactin. (howmed.net)

Diagnosis is by measurement of prolactin levels. (merckmanuals.com)

Basal GH secretion was inhibited by insulin (0.7 nM) after a 48-h lag period by approximately 50% (P less than 0.01, vs. untreated control cells). (jci.org)
The suppression of GH secretion was reversible, as removal of added insulin resulted in return of GH secretion to normal levels after 24 h. (jci.org)
Maximal suppression of basal GH secretion was achieved by 0.7 nM insulin, and these effects were prevented by simultaneous exposure of the cells to guinea pig anti-insulin serum (1:2,000). (jci.org)
The results show that insulin exerts a direct, specific inhibitory effect on basal and hydrocortisone-induced GH secretion by GH3 cells unrelated to glucose utilization by the cells. (jci.org)

As a dopamine (DA) agonist, it decreases the synthesis and secretion of PRL. (medscape.com)
Prolactin and dopamine: What is the connection? (sagepub.com)
What effects does dopamine have on the cells that produce prolactin? (sagepub.com)
Prolactin enhances dopamine secretion and thus exhibits feedback inhibition of its own secretion. (medscape.com)

Too much prolactin after menopause can lead to hypothyroidism. (medicalnewstoday.com)

The fact that if a woman became pregnant whilst lactating, her milk secretion would cease, is an important point to which we will return later. (nzdl.org)
Prolactin hormone: causes a woman's breasts to make milk after pregnancy. (mayfieldclinic.com)
Lactation is the term used for secretion of milk from the breast (mammary glands). (tandurust.com)
Prolactin is the hormone mainly responsible for stimulating the breast to produce milk. (tandurust.com)
Although it may be a cause of embarrassment, milk secretion from breast in a non pregnant woman is harmless. (tandurust.com)
Damage to the nerves of nipple or breast can cause abnormal secretion of milk in a woman. (tandurust.com)
Disturbance in mechanism can elevate the prolactin level causing discharge of milk from mammary glands. (tandurust.com)
If the nipples are sucked frequently and regularly, the brain will think it as a signal to promote increased secretion of prolactin which concomitantly initiates milk secretion from breast. (tandurust.com)
Prolactin is a hormone that triggers the breasts to produce milk (lactation). (medlineplus.gov)
Its pulsatile rhythm orchestrates the complex machinery within a woman's body, driving the formation and secretion of milk. (metsminorleagueblog.com)
Ökar testosteronproduktionen och hämmar läkarundersökning visar blodtestshower chini prolactin matokeo ya mtihani 75 kiume Vad innebär låg IGF-1-test resultat referent värden för manliga 75 år 16 jan. 2021 - stort antal fall rapporterades 1985-86 när diagnostiska test blev tillgängliga och load, blood prolactin levels and breast milk volume. (netlify.app)
Se hela listan på verywellhealth.com Se hela listan på mayoclinic.org Prolactin is a hormone whose primary role is to promote breast milk production (lactation). (netlify.app)

Administration of the somatostatin analog octreotide at doses of 150 microg s.c. per day inhibited the secretion of both GH and TSH. (nih.gov)
The long-acting somatostatin analogue octreotide is used either as an adjuvant or primary therapy to lower GH levels in patients with acromegaly and may also induce pituitary tumor shrinkage. (endocrine-abstracts.org)

Aim: Clinical acromegaly is characterized by high GH secretion in the presence of high circulating IGF-I levels. (endocrine-abstracts.org)

Prolactin (Prl) secretion in children manifests circadian rhythm. (nel.edu)

We have examined the co‐pulsatility of luteinizing hormone (LH) and prolactin, LH and follicle‐stimulating hormone (FSH), and LH and α subunit in normal men. (elsevierpure.com)

The effects of antagonists of prolactin secretion were examined on overall protein synthesis in GH3 cells as a function of cellular Ca2+ depletion and restoration at varying concentrations of extracellular Ca2+. (aspetjournals.org)
[ 13 ] The precise pathophysiologic mechanism is unknown, but it is speculated to be associated with the effects of prolactin on surfactant synthesis, whole-body water regulation, or gastrointestinal maturation. (medscape.com)

Almost all pituitary tumors are noncancerous (benign). (medlineplus.gov)

Any tumor that grows out of the pituitary can compress optic nerve tracts, including the chiasm. (merckmanuals.com)
Tumors may also compress or destroy pituitary or hypothalamic tissue, impairing hormone production or secretion. (merckmanuals.com)

Thyrotropin releasing hormone stimulation showed blunt response of TSH but good response for prolactin. (medassocthai.org)

Previous studies have demonstrated changes in p27 protein expression, in human pituitary tumours,especially in corticotroph tumours, where p27 prot. (endocrine-abstracts.org)
Prolactin receptor gene expression in rat splenocytes and thymocytes during Therefore, PRL-R expression at both protein and mRNA levels was examined DAA Xtreme Prolact-Block - Innovativ, säker och potent muskelökare från Olimp Sport Nutrition. (netlify.app)
IGSF1 was localized to thyrotrope cells, implicating the protein in pituitary control of the thyroid. (medscape.com)

Although early studies of IGSF1 ran into roadblocks and blind alleys, armed with the results of detailed clinical investigations, powerful mouse models, and new reagents, the field is now poised to discover IGSF1's function in endocrine tissues, including the pituitary and testes. (medscape.com)

Pharmacokinetic/pharmacodynamic models were used to correlate the concentration of BCT in the effect compartment with the lowering of prolactin. (aspetjournals.org)
Because we demonstrated that the concentration of hydroxylated metabolites after oral administration is 55-fold that of BCT, it can be concluded that BCT activity in the pituitary after oral administration is mediated by its metabolites. (aspetjournals.org)
Prolactin concentration in follicular fluid during in vitro fertilization (IVF) correlates with the oocyte maturation level and fertilization rate. (medscape.com)

Part of the immunosuppressive effects of cyclosporine may be mediated through a competitive antagonistic action at the prolactin receptor site. (medscape.com)

Prolactin receptors have been found on human T lymphocytes and B lymphocytes, and some data support T-lymphocyte dependence on prolactin for maintenance of immune competence. (medscape.com)

The male reproductive system consists of a pair of testes that produce sperm (or spermatozoa ), ducts that transport the sperm to the penis and glands that add secretions to the sperm to make semen (see diagram 13.2). (wikibooks.org)
This is the reason why the testes are located in a bag of skin called the scrotal sacs (or scrotum ) that hangs below the body and where the evaporation of secretions from special glands can further reduce the temperature. (wikibooks.org)
The heterocrine glands are glands that have two functions (hormone secretion and certain additional functions) (e.g., pancreas, testes, ovaries, etc). (vedantu.com)

Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. (aspetjournals.org)

Dihydroxylated metabolites, as well as monohydroxylated metabolites, were effective in reducing in vitro prolactin secretion. (aspetjournals.org)

We present a 49 year old male patient with thyroid stimulating hormone (TSH) producing pituitary macroadenoma. (medassocthai.org)

The lateral aspects of the pituitary are adjacent to the cavernous sinuses (see the image below). (medscape.com)

Surgically, transsphenoidal pituitary adenomectomy is the preferred treatment in patients with microprolactinomas and in most patients with macroprolactinomas. (medscape.com)

Anatomy44

Organisms13

Diseases24

Chemicals and Drugs111

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes39

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science4

Health Care2

Gland40

Adenomas15

Adenoma10

Hormones15

Prolactinoma4

Hormone prolactin3

Anterior9

Secrete prolactin2

Hypothalamus8

Level of prolactin3

Lactotrophs1

Serum prolactin8

High prolactin3

Posterior Pituitary1

Hyperprolactinemia3

Inhibition of prolactin2

Stalk1

Reported pituitary macroadenoma1

Lower prolactin2

Gonadotropin-releasi1

Growth12

ACTH1

Stimulates3

Occur1

Apoplexy3

Symptoms4

Deficiency4

Inhibitory Hormone1

Diagnosis1

Insulin4

Dopamine4

Hypothyroidism1

Milk12

Somatostatin2

Acromegaly1

Circadian rhythm1

Follicle1

Synthesis2

Benign1

Compress2

Thyrotropin1

Protein3

Clinical1

Concentration3

Receptor1

Lymphocyte1

Glands3

Inhibitors1

Vitro1

Thyroid-stimula1

Cavernous sinuses1

Surgically1