• Ion mobility spectrometry (IMS) has emerged as a powerful alternative to classical separation techniques. (polyphenols-site.com)
  • Here you will find information about the Annual Workshop on SIMS - the non profit organization devoted to education on various aspects of secondary ion mass spectrometry. (upenn.edu)
  • The regular purge and trap extraction followed by analysis with gas chromatography-mass spectrometry (GC-MS) usually involve a complicated assembly of facilities, more working space, long sample preparation time, and headspace solid-phase microextraction (SPME). (hindawi.com)
  • Differentiation of Mesenchymal Stem Cells under Hypoxia and Normoxia: Lipid Profiles Revealed by Time-of-Flight Secondary Ion Mass Spectrometry and Multivariate Analysis. (merlninstitute.com)
  • Current methods for detecting BoNT include a mouse cause human botulism (A, B, E, and F). We developed a bioassay (2-4) and an enzyme-linked immunosorbent assay rapid, mass spectrometry-based method (Endopep-MS) to (ELISA) (5,6). (cdc.gov)
  • The product peptides derived from the endopeptidase injection containing a sample with more than a minimum activities of BoNTs are detected by matrix-assisted laser- lethal dose show symptoms of botulinum intoxication and desorption ionization time-of-flight mass spectrometry. (cdc.gov)
  • In the mouse bioassay, when the injected matography-tandem mass spectrometry method for quan- dose is high, mice typically develop signs of botulism with- tifying active toxin, where the amount of toxin can be in 8 hours. (cdc.gov)
  • Mice receiving the appropriate anti-BoNT serotype anti- a unique cleavage site on a unique peptide, the mass-spe- body are asymptomatic and survive, while mice treated cific product peptides detected by mass spectrometry dif- with the other serotype antibodies show symptoms of botu- ferentiate active BoNT serotypes. (cdc.gov)
  • The main disadvantage of flight mass spectrometry (MALDI-TOF-MS) or by high- the mouse bioassay is that it requires euthanizing many ani- performance liquid chromatography (HPLC)-electrospray mals. (cdc.gov)
  • It also requires several days to determine the toxin ionization-tandem mass spectrometry (HPLC- level and type (4-6). (cdc.gov)
  • These interactions were selected on the basis of importance in previous peptide DOEs and predictions about possible fundamental mass spectrometry instrument component interactions. (technuc.com)
  • using MALDI-TOF mass spectrometry. (degruyter.com)
  • 1990. Monitoring exposure to 4,4´-methylenedianiline by the gas chromatography-mass spectrometry determination of adducts to hemoglobin. (cdc.gov)
  • 1992. Quantification of 4,4´-diaminodiphenylmethane by gas chromatography-negative-ion chemical-ionization mass spectrometry. (cdc.gov)
  • Gas chromatography negative ion chemical ionization mass spectrometry of hydrolyzed human urine and blood plasma for the biomonitoring of occupational exposure to 4,4 methylenebisaniline. (cdc.gov)
  • The ultra-high-performance liquid chromatography tandem mass spectrometry (UHPLC-MS) method was built to quantify the casein glycomacropeptide (CGMP) in bovine dairy products accurately based on targeted proteomics. (bvsalud.org)
  • Qualitative analysis of theoretical peptides was carried out using high-resolution mass spectrometry (HRMS) and protein software. (bvsalud.org)
  • Third trimester archived spot urine samples were analyzed by online solid phase extraction coupled with high performance liquid chromatography isotope dilution tandem mass spectrometry. (biomedcentral.com)
  • Substances were identified and documented using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry. (biomedcentral.com)
  • Proteins interacting with HDPs were identified by co-immunoprecipitation coupled with mass spectrometry. (biomedcentral.com)
  • Utilizing Secondary Ion Mass Spectrometry (SIMS) for in-line metrology is a newly emerging method of process control that requires contamination-free measurements, enabling SIMS on product wafers. (semiengineering.com)
  • Iranian olive leaf essential oil components were extracted by microwave-assisted hydrodistillation and analyzed using gas chromatography-mass spectrometry. (sharif.edu)
  • The components of Iranian spearmint essential oil were identified and quantified using gas chromatography-mass spectrometry (GC-MS) combined with chemometric tools. (sharif.edu)
  • Here, we present a highly sensitive multi-biomarker approach by a sophisticated combination of steps during sample preparation including a Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) extraction followed by a solid phase extraction (SPE) cleanup and utilizing stable isotopes for compensating challenging matrix effects. (frontiersin.org)
  • Total phenol monomers and oligomers were detected by Folin-Ciocaltau assay after fractionation by solid phase extraction (SPE). (degruyter.com)
  • For better cleanup, solid phase extraction (SPE), including dual-layer cartridges, can be used. (sigmaaldrich.com)
  • Extraction was done by Soxhlet apparatus with solvents of n-hexane, DCM (dichloromethane) and MeOH (methanol), and then, fractionation of extracts was accomplished through various chromatographic techniques including VLC (vacuum liquid chromatography) approach and SPE (solid phase extraction) technique. (springeropen.com)
  • These cartridges often contain graphitized carbon black (GCB) in the top bed and primary-secondary amine (PSA) in the bottom bed. (sigmaaldrich.com)
  • The prevalent methods are carried out on gas chromatography-mass spectrometer, regardless of the water or fish flesh. (hindawi.com)
  • While the magnitude of these effects are instrument specific previous work on mass spectrometer peptide optimization has indicated that the basic relationships behind these parameters are to some extent Keratin 10 antibody universal54 58 A-889425 Despite evidence that design of experiments can lead to improvements in protein abundance to date there has been no parallel investigation of MS parameters for glycans. (technuc.com)
  • Compounds are analyzed by a thermal desorption comprehensive two-dimensional gas chromatography-quadrupole mass spectrometer (TD-GC × GC-qMS). (bvsalud.org)
  • Quartz filters were utilized to trap particles, and organics were analyzed by a comprehensive two-dimensional gas chromatography-mass spectrometer (GC × GC-MS) coupled with a thermal desorption system (TDS). (bvsalud.org)
  • The Cassini Plasma Spectrometer (CAPS) will measure the flux of ions as a function of mass per charge, and the flux of ions and electrons as a function of energy per charge and angle of arrival relative to the instrument. (esa.int)
  • The Ion and Neutral Mass Spectrometer (INMS) is intended to measure positive ion and neutral species composition and structure in the upper atmosphere of Titan and magnetosphere of Saturn, and to measure the positive ion and neutral environments of Saturn's icy satellites and rings. (esa.int)
  • Rinse with either 2 % ammonium hydroxide for basic analytes or 1 % formic acid for acidic analytes to ensure hydrophobic interaction or increase the sorbent mass to retain more polar compounds. (agilent.com)
  • Mixtures of neutralizing anti- detection of the unique peptide products by mass spec- bodies are given to mice in conjunction with the sample. (cdc.gov)
  • Each HZE ion consists of a nucleus with no orbiting electrons, meaning that the charge on the ion is the same as the atomic number of the nucleus. (wikipedia.org)
  • The ionization patterns in molecules, cells, tissues, and the resulting biological harm are distinct from high-energy photon radiation: X-rays and gamma rays, which produce low-linear energy transfer (low-LET) radiation from secondary electrons. (wikipedia.org)
  • In this application, a different dual-layer SPE cartridge was used in the cleanup of extracts of turmeric powder prior to pesticide analysis by GC/MS/MS and LC/MS/MS. This cartridge, the Supelclean™ Ultra 2400, was designed for the cleanup of acetonitrile extracts made from difficult matrices such as dry commodities (spices, tea, etc.) prior to pesticide residue analysis. (sigmaaldrich.com)
  • The combination of these sorbents in an SPE format offers more capacity than QuEChERS cleanup, and compared to traditional GCB/PSA dual layer cartridges, does not require the use of toluene in the elution solvent to recover planar pesticides. (sigmaaldrich.com)
  • The Third International SPES Workshop will take place at LNL from 10th to 12th October 2016, with the aim to summarize the present status and upgrades of the facility and discuss the physics with radioactive ion beams at SPES and the future experimental campaigns. (infn.it)
  • Drug substances and counterions are determined by HPLC (often on reversed-phase columns) and by ion chromatography (IC), respectively. (chromatographyonline.com)
  • The aims of this study were, first, to confirm that mass spectrometric analysis of an array of hormones and organic acids would yield similar results in both liquid and dried urine, and, second, to determine if collection of four dried spot urine samples could be substituted for a 24-h collection when measuring reproductive hormones. (biomedcentral.com)
  • Elucidating the individual effects of calcium and phosphate ions on hMSCs by using composite materials. (merlninstitute.com)
  • This channel is activated by signalling molecules inside cells, called 'cyclic nucleotides', and its activity ultimately leads to calcium ions flowing into the sperm cell's tail. (elifesciences.org)
  • This influx of calcium ions in turn controls the beating of the tail and, thereby, steers the sperm cell towards the egg. (elifesciences.org)
  • In zebrafish sperm, a more alkaline pH inside the cell causes calcium ions to flow in and this influx of calcium ions triggers a unique spinning-like swimming movement that is different from the swimming of other sperm from other species. (elifesciences.org)
  • Mycotoxins are toxic secondary metabolites produced by a variety of fungi, including Aspergillus, Penicillium , and Fusarium species. (frontiersin.org)
  • The SPES radioactive ion beam project of INFN is in a quite advanced state. (infn.it)
  • SIMS measurements of negative ions are usually associated with a Cesium primary ion beam. (semiengineering.com)
  • All main and quadratic effects and selected secondary interactions (Supplementary Table 4) were assessed for inclusion within the model using a forward stepwise approach and selecting for the BIC value. (technuc.com)
  • HZE ions are the high-energy nuclei component of galactic cosmic rays (GCRs) which have an electric charge of +3 e or greater - that is, they must be the nuclei of elements heavier than hydrogen or helium. (wikipedia.org)
  • The abbreviation "HZE" comes from high (H) atomic number (Z) and energy (E). HZE ions include the nuclei of all elements heavier than hydrogen (which has a +1 e charge) and helium (which has a +2 e charge). (wikipedia.org)
  • Furthermore A-889425 we included an extra main effect term absolute ion abundance which quantifies a known interaction between the MS2 AGC underfill ratio and ionization time terms (Supplementary Equation 2). (technuc.com)
  • For HZE ions that originate from solar particle events (SPEs), there is only a small contribution toward a person's absorbed dose of radiation. (wikipedia.org)
  • Bond Elut Plexa PCX is a mixed-mode ion exchanger with a hydrophobic polymer similar to Bond Elut Plexa and strong cation exchange sites that remove neutral and acidic interferences from the matrix, concentrate basic analytes and improve analytical performance for basic analytes. (agilent.com)
  • Models (Supplementary Equation 1) were generated for five distinct responses including the ion abundance A-889425 for glycans belonging to each class (H9 H5N4F1 H6N5A3) percent sialic acid loss and the number of H5N4F1 MS/MS spectra collected. (technuc.com)
  • Low molecular mass heparins are salts of sulphated glucosaminoglycans having a mass average molecular mass less than 8000. (chromatographyonline.com)
  • Their energies per atomic mass unit are all significantly less than protons found in the same SPE, meaning that protons are by far the largest contribution to astronaut body exposure during SPEs. (wikipedia.org)
  • During a SPE, there is such a small amount of heavy ions generated that their effects are limited. (wikipedia.org)
  • High-energy nuclear physics Cosmic radiation Solar energetic particles Spaceflight radiation carcinogenesis Central nervous system effects from radiation exposure during spaceflight - HZE CNS health effects Swift heavy ion Ultra-high-energy cosmic ray - Cosmic-ray particle with a kinetic energy greater than 10^18 eV "Can people go to Mars? (wikipedia.org)
  • These LoIs will also cement the future collaborations around SPES and define the ancillary equipments that will be needed to ensure a competitive scientific programme with the SPES facility. (infn.it)
  • Increase sorbent mass for increased ion exchange capacity. (agilent.com)
  • Definitive screening designs represent a new class of split-plot screening designs that can be used to produce second-order models which include all quadratic and secondary interactions. (technuc.com)
  • LED red light, to the skin cells to the secondary optical SPA. (olansichina.com)
  • In 2009, researchers identified a potassium ion channel, called CNGK, that starts the electrical signal in the sperm cells of sea urchins. (elifesciences.org)
  • The acute transient neurotoxicity observed in rats exposed to MeI is best supported by a mode of action involv- ing modification of ion currents by the parent chemical in nerve cells. (cdc.gov)
  • In addition to the HZE ions from cosmic sources, HZE ions are produced by the Sun. During solar flares and other solar storms, HZE ions are sometimes produced in small amounts, along with the more typical protons, but their energy level is substantially smaller than HZE ions from cosmic rays. (wikipedia.org)
  • Space radiation is composed mostly of high-energy protons, helium nuclei, and high-Z high-energy ions (HZE ions). (wikipedia.org)
  • Contribution of high charge and energy (HZE) ions during Solar-particle event of September 29, 1989 (Report). (wikipedia.org)
  • A secondary aim of this study was to determine differences in BPA concentrations between women who delivered less than or equal to 37 weeks of gestation and after the completion of 37 weeks of gestation. (biomedcentral.com)
  • The SPE Library contains thousands of papers, presentations, journal briefs and recorded webinars from the best minds in the Plastics Industry. (4spe.org)
  • GCRs typically originate from outside the Solar System and within the Milky Way galaxy, but those from outside of the Milky Way consist mostly of highly energetic protons with a small component of HZE ions. (wikipedia.org)
  • Although HZE ions make up a small proportion of cosmic rays, their high charge and high energies cause them to contribute significantly to the overall biological impact of cosmic rays, making them as significant as protons in regard to biological impact. (wikipedia.org)
  • HZE ions are rare compared to protons, for example, composing only 1% of GCRs versus 85% for protons. (wikipedia.org)
  • To produce a widget requires 4 hours of working time on machine A and 2 hours on machine B. It is based on the experience collected by the Milano group on large mass arrays of low-temperature calorimeters for rare decays [34]. (forexsignal300.com)
  • SpectroscopyNOW.com, a "Community of Interest" website, has become the definitive spe. (upenn.edu)
  • Create the basis for defining priorities for the SPES day-1 experiments. (infn.it)
  • Find the lat-est issues, infor-ma-tion on the Paper Brigade New Israeli Fic-tion prize, adver-tis-ing details, and more. (jewishbookcouncil.org)