AnatomyDiseasesAnalytical, Diagnostic and Therapeutic Techniques and Equipment
Chondromatosis, SynovialChondromatosisJoint Loose BodiesChondromaCranial Fossa, MiddleTemporomandibular Joint DisordersArthroscopesMetacarpophalangeal JointChondrosarcomaRadiography, PanoramicSynovial Membrane
MembraneBodiesPigmented villonoduIntra-articularTemporomandibular jointBenignDiagnosisExpression in the synovialFluidEtiologyNodulesOccursBoneExtraarticularJointsFindingsChondrosarcomaEffusionFamilialInflammationMalignantPrimary or secondaryElbow jointJointCartilaginousRadiographKneeUnclearPatientsAspirateInfectionPatientConditionDiseaseReportsCases
Membrane11
Bodies14
  • The pain, swelling, and mechanical symptoms of synovial chondromatosis and its generation of loose bodies have historically been treated with surgery. (medscape.com)
  • Some histochemical evidence shows low proliferation activity in the synovial loose bodies. (medscape.com)
  • 19] High levels of bone morphogenic protein (BMP)-2 and BMP-4 mRNA have also been isolated from free bodies and synovial tissue. (medscape.com)
  • Synovial chondromatosis is a benign tumor-like lesion of soft tissue cartilage such as joint synovium, which can lead to the formation of multiple cartilage nodules or loose bodies [ 1 ]. (biomedcentral.com)
  • Moreover, relative studies had reported that fibroblast growth factor 2 (FGF-2) or transforming growth factor beta 3 (TGF-β3) were responsible for the formation of cartilaginous loose bodies and involved in the pathogenesis of synovial chondromatosis [ 9 ]. (biomedcentral.com)
  • Loose bodies were nourished by synovial fluid and have the ability to grow locally. (biomedcentral.com)
  • On arthrographic images, the nodular synovial thickening of PVNS can appear as filling defects within the joint, findings similar to those seen with synovial osteochondromatosis or rheumatoid arthritis (rice bodies) (2,4). (facmedicine.com)
  • Free bodies and synovium isolated from synovial chondromatosis patients expressed high levels of BMP-2 and BMP-4 mRNAs. (shengsci.com)
  • Synovial chondromatosis associated, intra-articular loose bodies are usually small in size. (hippokratia.gr)
  • We present the case of a patient with synovial chondromatosis associated giant intra-articular loose bodies located under the patella and the intercondylar fossa, treated successfully with combined arthroscopic and open excision. (hippokratia.gr)
  • Giant intra-articular loose bodies should be considered when treating patients with synovial chondromatosis. (hippokratia.gr)
  • Arthroscopy confirms the diagnosis, allows the thorough examination of the knee joint, and subsequent excision of small or medium size attached synovial nodules or intra-articular loose bodies. (hippokratia.gr)
  • The current article presents the case of a patient with giant intra-articular loose bodies related to synovial chondromatosis of the knee, who was successfully treated with a combination of knee arthroscopy and arthrotomy. (hippokratia.gr)
  • They should be differentiated from synovial chondromatosis where loose bodies are relatively larger in size, round to ovoid in shape and impart slightly high signal on T2-weighted images. (neuroradiologycases.com)
Pigmented villonodu1
  • Image-guided synovial biopsy, using either ultrasonography (US) or CT, has been found to be safe and effective for establishing a definitive diagnosis of synovial lesions (eg, synovial chondromatosis or pigmented villonodular synovitis) before surgical or other intervention. (medscape.com)
Intra-articular1
  • Moreover, synovial chondromatosis can be found intra-articular as well as extra-articular (like the extensor digitorum longus tendon), which were still relatively rare in the literature [ 5 ]. (biomedcentral.com)
Temporomandibular joint2
  • 20] Additionally, elevated levels of IL-6, aggrecan, and VEGF-A have been found in cases of synovial chondromatosis of the temporomandibular joint. (medscape.com)
  • This case series reviews 2 patients worked up and treated for unilateral synovial chondromatosis of the temporomandibular joint (TMJ). (bvsalud.org)
Benign4
  • Synovial chondromatosis is considered a benign process associated with an extremely low risk of malignancy. (medscape.com)
  • To validate a technique for reproducible measurement of the osteochondroma cartilage cap with computed tomography (CT) and magnetic resonance (MR) imaging and to reevaluate the correlation of the thickness of the cartilage cap with pathologic findings to improve noninvasive differentiation of benign osteochondromas from secondary chondrosarcomas. (rsna.org)
  • Primary synovial chondromatosis is a rare benign disease that occurs in the joint mucosa. (biomedcentral.com)
  • Synovial chondromatosis is a benign monoarticular arthropathy characterized by the formation of hyaline cartilage multiple small nodules around the affected joint 1 . (hippokratia.gr)
Diagnosis3
Expression in the synovial1
  • Further, it inhibited Osteocalcin expression in the synovial cells. (shengsci.com)
Fluid8
  • Coronal T2-weighted MRI of patient with synovial chondromatosis demonstrates punctate areas of low intensity within synovial fluid. (medscape.com)
  • Arthrocentesis is used to obtain a sample of synovial fluid if the physical findings suggest infection. (medscape.com)
  • Although interleukin (IL)-6 and vascular endothelial growth factor (VEGF)-A have been noted to be elevated in synovial fluid samples, these findings do not yet play a significant role in clinical practice. (medscape.com)
  • Fukuhara et al identified elevated levels of chondrocalcin in the synovial fluid of patients with synovial chondromatosis. (medscape.com)
  • Similarly, levels of interleukin (IL)-6 and vascular endothelial growth factor (VEGF)-A in synovial fluid may someday have clinical utility, but at present, they remain of primarily academic interest. (medscape.com)
  • The epiphyseal cartilage is avascular, so that it only receives its nutrition via osmosis from the synovial fluid. (vin.com)
  • Invasion of the cracks by synovial fluid, thus coming into contact with subchondral bone also promotes inflammation. (vin.com)
  • Synovial fluid aspirate was sent for culture and cytological examination, which were negative. (hippokratia.gr)
Etiology1
Nodules4
  • Secondary widening of the joint space may be noted, even if the nodules are not directly visible. (medscape.com)
  • The first was a 58-year-old female evaluated and treated for synovial chondromatosis of the left TMJ using an arthrotomy of the joint to remove the cartilaginous and osteocartilaginous nodules. (bvsalud.org)
  • The second is a 63-year-old male who was evaluated and treated for synovial chondromatosis of the right TMJ with the removal of extracapsular masses and an arthrotomy with intra-joint removal of nodules. (bvsalud.org)
  • BACKGROUND: Synovial chondromatosis is an uncommon metaplastic process of the synovial lining that results in the formation of cartilaginous nodules within joints or their associated bursae or tendon sheaths. (bvsalud.org)
Occurs4
  • Synovial chondromatosis occurs twice as commonly in males as females and usually in their forties. (wikipedia.org)
  • Primary synovial chondromatosis, which is more rare, occurs spontaneously and does not appear to relate to any pre-existing conditions. (wikipedia.org)
  • Secondary synovial chondromatosis is the more common form and often occurs when there is pre-existent osteoarthritis, rheumatoid arthritis, osteonecrosis, osteochondritis dissecans, neuropathic osteoarthropathy (which often occurs in diabetic individuals), tuberculosis, or osteochondral fractures (torn cartilage covering the end of a bone in a joint) in the affected individual. (wikipedia.org)
  • Secondary: Osteoarthritis that occurs after injury or inflammation in a joint. (atticasportsclinic.gr)
Bone3
  • Synovial chondromatosis is a locally aggressive bone tumor of the cartilaginous type. (wikipedia.org)
  • Bone morphogenetic proteins are involved in the pathobiology of synovial chondromatosis. (shengsci.com)
  • Synovial tissue samples were collected for frozen section biopsies that showed areas of normal bone, normal hyaline cartilaginous tissue, and partly fibro-cartilaginous tissue containing focal degenerative lesions and focal necrosis. (hippokratia.gr)
Extraarticular2
  • Extraarticular chondromatosis is rarer than intraarticular chondromatosis, and the knee is affected less frequently than the smaller joints of the hands and feet. (bvsalud.org)
  • Extraarticular synovial chondromatosis: review of epidemiology, imaging studies, microscopy and pathogenesis, with a report of an additional case in a child. (umassmed.edu)
Joints3
  • these occur most frequently in the hip (more than 90% of cases) and shoulder (more than 70% of cases) (5) and may be due to a relatively small, more confined joint space and secondary increased pressure in these joints. (facmedicine.com)
  • Synovial chondromatosis is a rare pathology that involves most frequently the weight-bearing joints. (bvsalud.org)
  • CASE: Synovial chondromatosis is a rare condition affecting synovial joints. (bvsalud.org)
Findings2
  • All findings should be within normal limits in persons with primary synovial chondromatosis. (medscape.com)
  • Free chapter on ultrasound findings of synovial chondromatosis affecting the subacromial-subdeltoid bursa available at ShoulderUS.com Fuller E, Bharatha A, Yeung R, Kassel EE, Aviv RI, Howard P, Symons SP. (wikipedia.org)
Chondrosarcoma1
Effusion1
  • Moderate hip joint effusion and synovial thickening and enhancement are seen. (jbjs.org)
Familial1
Inflammation1
  • Results of these tests are expected to be normal in persons with primary synovial chondromatosis, but they may be elevated in persons with secondary synovial chondromatosis due to systemic inflammation from a condition such as rheumatoid arthritis (RA). (medscape.com)
Malignant1
Primary or secondary2
Elbow joint2
  • To our knowledge, this is the first report of adolescent bilateral elbow joint synovial chondropathy, and the patient is a gymnast with a particular occupation. (biomedcentral.com)
  • The elbow joint is a complex hinge-type synovial joint with an important role in the mobilization of the upper limb, linking the hand, wrist, and shoulder. (encyclopedia.pub)
Joint2
Cartilaginous1
  • These results suggest that BMPs are involved in the pathobiology of cartilaginous and osteogenic metaplasia observed in synovial chondromatosis. (shengsci.com)
Radiograph1
Knee2
Unclear1
Patients2
  • However, online communities for synovial chondromatosis patients have yielded a stark contrast, with equal representation from both genders and members diagnosed as young as late teenage/early 20s. (wikipedia.org)
  • CONCLUSION: Synovial chondromatosis should be considered in pediatric patients presenting with shoulder pain and loss of function with potential for recurrence. (bvsalud.org)
Aspirate1
  • Given the acuity of the presentation, 49,500 WBC/μL in the synovial aspirate, and the mass identified on MRI, a recommendation for operative irrigation of the hip and excision of the mass was made and the parents decided to proceed. (jbjs.org)
Infection1
  • The infection resides in synovial or periarticular tissues and is usually bacterial-in younger adults. (msdmanuals.com)
Patient1
  • We present a case of a 13-year-old male patient with shoulder pain who was diagnosed with synovial chondromatosis and a posterior labral tear. (bvsalud.org)
Condition1
  • In the previous reports describing this condition after THA, presentation was in the form of groin pain or mass or limb swelling secondary to venous occlusion. (openorthopaedicsjournal.com)
Disease1
Reports1
Cases1
  • A review of 155 cases of primary synovial chondromatosis by McCarthy et al identified only four cases of aggressive behavior and chondrosarcomalike histology (one in the elbow and three in the hip). (medscape.com)