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AminesAmidesAmine Oxidase (Copper-Containing)Biogenic AminesAmidohydrolasesMolecular StructureMagnetic Resonance SpectroscopyAmide SynthasesGlucagon-Like PeptidesPolyunsaturated AlkamidesEndocannabinoidsTyramineOctopamineStereoisomerismReceptors, Biogenic AmineHeterocyclic CompoundsSemicarbazidesStructure-Activity RelationshipModels, MolecularOxidoreductases Acting on CH-NH Group DonorsCarbamatesKineticsSpectrophotometry, InfraredDeuterium Exchange MeasurementDeuteriumSpectroscopy, Fourier Transform InfraredHydrogenAmino Acid SequenceCatalysisProtein ConformationMolecular Sequence DataHydrogen BondingMethylaminesArachidonic AcidsPeptidesHydrogen-Ion ConcentrationCannabinoid Receptor ModulatorsGlucagon-Like Peptide 1Substrate SpecificityMolecular ConformationMonoamine OxidaseProtonsSympathomimeticsProtein Structure, SecondaryEthylaminesSerotoninAminationChromatography, High Pressure LiquidDihydroxyphenylalanineEstersMass SpectrometryPhenethylaminesButylaminesNuclear Magnetic Resonance, BiomolecularBinding SitesNitrogen IsotopesHydrolysisModels, ChemicalPeptide FragmentsMonoacylglycerol LipasesIndicators and ReagentsCarboxylic AcidsOligopeptidesCyclizationCrystallography, X-RayReceptor, Cannabinoid, CB1CarcinogensToluidinesBiotransformationOxidation-ReductionWaterPhenylhydrazinesBenzylaminesReserpineSpectrum Analysis, RamanLanthanoid Series ElementsThermodynamicsNitrosaminesSolventsDipeptidesPolyaminesMonoamine Oxidase InhibitorsCircular DichroismProtein BindingPalladiumDrug DesignAcylationPeptoidsSpectrometry, Mass, Electrospray IonizationTemperatureReceptors, GlucagonMutagensKetonesCattleVesicular Biogenic Amine Transport ProteinsGlutamineDiaminesAminobiphenyl CompoundsSolutionsArylamine N-Acetyltransferase
AmmoniaReactAlcoholsAliphatic and aromaticSaltsAminoSynthesisReactsAcylFattyNitrogen atomCarboxylDerivativesCarbonylReactivityUndergoAldehydeBasicityCarboxylateCompoundsMethylamineCyclicAnilineCarbon atomLithiumReactionBondsChapterChemistrySolubilityTriethylamineUreaAcidsUrineDifferent structuresFormQuaternaryResidualPreparation
Ammonia7
React13
  • Primary amines react with ketones such as acetone , and most amines are incompatible with chloroform and carbon tetrachloride. (newworldencyclopedia.org)
  • Two amino acids with different side chains react when the amino-terminus (red) of one joins the carboxy-terminus (blue) of another are linked by an amide bond (green). (wikibooks.org)
  • Primary aliphatic amines react with nitrous acid to form aliphatic diazonium salts. (topperlearning.com)
  • Secondary and tertiary amines react with nitrous acid in a different manner. (topperlearning.com)
  • Tertiary amines do not react with benzenesulphonyl chloride. (topperlearning.com)
  • These NHS esters react with primary and secondary amine to form a stable amide linkage. (creativepegworks.com)
  • Nitrate (NO 3 − ) from drinking water and other nitrate sources is converted to nitrite (NO 2 − ) in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form teratogenic N -nitroso compounds (NOCs) under highly acidic environments as in the stomach. (biomedcentral.com)
  • ii) Secondary and tertiary amines can be distinguished by allowing them to react with Hinsberg's reagent (benzenesulphonyl chloride, C 6 H 5 SO 2 Cl). (multiverseiit.com)
  • Secondary amines react with Hinsberg's reagent to form a product that is insoluble in an alkali. (multiverseiit.com)
  • Tertiary amines, however, do not react with Hinsberg's reagent. (multiverseiit.com)
  • A dye is obtained when aromatic amines react with HNO 2 (NaNO 2 + dil.HCl) at 0-5°C, followed by a reaction with the alkaline solution of 2-naphthol. (multiverseiit.com)
  • Primary amines supported on resins also readily react with lactide, and this has been applied to remove unreacted monomer from PLA samples without affecting the polymer properties. (cnrs.fr)
  • Treatment of aromatic and aliphatic aldehydes with dibromoisocyanuric acid generated acyl bromide intermediates, which were employed to react with a variety of secondary and primary amines to give amides. (ewha.ac.kr)
Alcohols6
  • Thus the boiling point of amines is higher than those for the corresponding phosphines, but generally lower than the corresponding alcohols . (newworldencyclopedia.org)
  • Alcohols, or alkanols, resemble amines but feature an -OH group in place of NR 2 . (newworldencyclopedia.org)
  • Grid 3-oxidation of secondary alcohols to ketones. (rsc.org)
  • The important classes of organic compounds known as alcohols, phenols, ethers, amines and halides consist of alkyl and/or aryl groups bonded to hydroxyl, alkoxyl, amino and halo substituents respectively. (abcprofil.com)
  • For primary and secondary alcohols the reaction is rapid and nearly quantitative. (gelest.com)
  • The reaction is quite fast with primary and secondary alcohols and slower with tertiary alcohols. (gelest.com)
Aliphatic and aromatic2
  • On heating aliphatic and aromatic primary amines with chloroform and ethanolic KOH they form isocyanides or carbylamines which have foul odour. (topperlearning.com)
  • Carbylamine test: Aliphatic and aromatic primary amines on heating with chloroform and ethanolic potassium hydroxide form foul-smelling isocyanides or carbylamines. (multiverseiit.com)
Salts3
  • However, when stored with amine salts containing diisobutylamine, the change in color or formation of sludge of the oil is significantly reduced. (wikipedia.org)
  • Aromatic amines on treating with nitrous acid at low temperatures to form diazonium salts which are used in the synthesis of a variety of aromatic compounds. (topperlearning.com)
  • vi) Diazonium salts of aromatic amines are more stable than those of aliphatic amines. (multiverseiit.com)
Amino8
  • Higher amines have the prefix amino as a functional group. (newworldencyclopedia.org)
  • Amino acids consist of a primary amine bound to an aliphatic carbon atom (the so-called α-carbon), which in turn is bound to a carboxylic acid group. (wikibooks.org)
  • For an amino acid like leucine or alanine with non-reactive sidechains, I think you'd need to di-protect the amine as a phthalimide or similar reagent, and then convert it into an acid chloride with SOCl2 or oxalyl chloride. (masterorganicchemistry.com)
  • This reagent introduces acyl groups into functional groups (hydroxy-, mercapto-, and amino groups) with active hydrogen to convert them into esters, thioesters, and amides. (fujifilm.com)
  • An amino acid molecule contains at least one carboxylic acid group ( -COOH ) and at least one amine group ( -NH 2 ). (docbrown.info)
  • If the amine group is on the first carbon that can have a hydrogen atom substituted by a another different atom of group it is known as an alpha ( α ) amino acid. (docbrown.info)
  • If the amine is on the 3rd carbon it is a beta (β) amino acid. (docbrown.info)
  • If the amine is on the 4th carbon it is a beta (γ) amino acid. (docbrown.info)
Synthesis6
  • Our subject experts thoroughly explain solved cases based on the basicity of amines, synthesis, and reactions that amines undergo. (extramarks.com)
  • vii) Gabriel phthalimide synthesis is preferred for synthesising primary amines. (multiverseiit.com)
  • A one-pot synthesis of secondary and tertiary amides from carboxylic acids and amines by using SOCl2 has been developed. (abcprofil.com)
  • 20g/100ml, soluble in ethanol, melting point 110-114 ° C, made use of as triggering reagent for carboxyl group in amide synthesis, also made use of for triggering phosphate group, protein and also nucleic acid cross-linking as well as immunoconjugate made. (zhishangchemical.com)
  • A facile method for the direct synthesis of amides from aldehydes is described. (ewha.ac.kr)
  • This facile and efficient procedure provides potential strategy for the direct synthesis of amides from aldehydes. (ewha.ac.kr)
Reacts6
  • Diisobutylamine reacts with arylphosphonic dichlorides to give arylphosphonic amines. (wikipedia.org)
  • Diisobutylamine reacts with dimethyldioxirane to give diisobutylhydroxylamine, as typical for oxidation of secondary amines to give hydroxylamines. (wikipedia.org)
  • Hinsberg's reagent or benzenesulphonyl chloride (C 6 H 5 SO 2 Cl) reacts with primary amines and secondary amines to form sulphonamides. (topperlearning.com)
  • Primary amine reacts with benzenesulphonyl chloride to form N-ethylbenzenesulphonyl amide. (topperlearning.com)
  • Aniline reacts with carboxylic acids [1] or more readily with acyl chlorides such as acetyl chloride to give amides . (wikidoc.org)
  • The benzaldehyde group readily reacts with primary amines, aminooxy and hydrazide. (axispharm.com)
Acyl2
  • The conversion of carboxylic acids to their corresponding acid chlorides occurs rapidly in the presence a tertiary amine base and 3,3-dichlorocyclopropenes via aromatic cation-activated nucleophilic acyl substitution. (abcprofil.com)
  • Carbodiimide militarizes the development of amide bonds, carboxylic acids and also amines by triggering carboxylate to develop O-acyl urea. (zhishangchemical.com)
Fatty2
Nitrogen atom3
  • Aromatic amines have the nitrogen atom connected to an aromatic ring as in anilines . (newworldencyclopedia.org)
  • A peptide bond consists of a carbonyl group's carbon atom directly bound to the nitrogen atom of a secondary amine. (wikibooks.org)
  • In this degradation reaction,migration of alkyl or aryl group takes place from carbonyl carbon of the amide to the nitrogen atom. (topperlearning.com)
Carboxyl2
  • The particle of EDC (or EDAC) has a linear framework and also is used in the condensation response of carboxyl teams with primary amines, and has actually been widely made use of. (zhishangchemical.com)
  • EDAC is commonly made use of as a carboxyl activator for amide bonding with main amines. (zhishangchemical.com)
Derivatives2
  • Hydrogen bonding significantly influences the properties of primary and secondary amines as well as the protonated derivatives of all amines. (newworldencyclopedia.org)
  • So direct oxidation of aromatic amines is not useful since it gives tarry oxidation products along with some nitro derivatives. (topperlearning.com)
Carbonyl1
  • An important exception to this rule is that compounds of the type RC(O)NR 2 , where the C(O) refers to a carbonyl group, are called amides rather than amines. (newworldencyclopedia.org)
Reactivity1
  • Interestingly, the presence of an amine group strongly increases the reactivity of the aromatic ring, due to an electron-donating effect. (newworldencyclopedia.org)
Undergo2
  • N-Methyl-tert-butylamine as a secondary amine can undergo chemical reactions to form desired amines [4] and amides [5] . (georganics.sk)
  • The terminal carboxylic acid can undergo reactions with primary and secondary amines in the presence of EDC , HATU and DCC to form a stable amide bond. (axispharm.com)
Aldehyde1
  • In addition, the NP surface was hydrophobized by covalent conjugation of dodecyl aldehyde via its surface primary amine groups. (nature.com)
Basicity1
  • The aromatic ring strongly decreases the basicity of the amine, depending on its substituents. (newworldencyclopedia.org)
Carboxylate1
Compounds4
  • Amines are organic compounds and a type of functional group that contain nitrogen as the key atom. (newworldencyclopedia.org)
  • This broad range of medications contain compounds such as secondary amines, tertiary amines, and amides. (biomedcentral.com)
  • Write IUPAC names of the following compounds and classify them into primary, secondary and tertiary amines. (multiverseiit.com)
  • Q1) Write IUPAC names of the following compounds and classify them into primary, secondary and tertiary amines. (ncertian.com)
Methylamine2
  • Methylamine (being an aliphatic primary amine) gives a positive carbylamine test, but dimethylamine does not. (multiverseiit.com)
  • i) Methylamine and dimethylamine (ii) Secondary and tertiary amines (iii) Ethylamine and aniline (iv) Aniline and benzylamine (v) Aniline and N-methylaniline. (ncertian.com)
Cyclic1
  • Daniel Seidel, University of Florida, Gainesville, USA, and colleagues have developed a method for the regioselective α'-cyanation of unprotected cyclic amines that have a pre-existing substituent in the other α position (example product pictured). (chemistryviews.org)
Aniline5
  • The aromatic amines, such as aniline , have their lone pair electrons conjugated into the benzene ring, thus their tendency to engage in hydrogen bonding is diminished. (newworldencyclopedia.org)
  • Aromatic amines such as aniline are generally much weaker bases than aliphatic amines. (wikidoc.org)
  • The amides formed from aniline are sometimes called "anilides", for example CH 3 -CO-NH-C 6 H 5 is acetanilide . (wikidoc.org)
  • Aniline combines directly with alkyl iodides to form secondary and tertiary amines. (wikidoc.org)
  • Aniline, being an aromatic primary amine, gives positive carbylamine test. (multiverseiit.com)
Carbon atom2
Lithium6
  • The present invention relates to electrolyte solutions, electrochemical devices, lithium ion secondary batteries, and modules. (justia.com)
  • Then, electrochemical devices which are non-aqueous electrolyte batteries, such as lithium ion secondary batteries, have gained attention because such batteries have a higher energy density than nickel-cadmium batteries and nickel-hydrogen batteries. (justia.com)
  • Typical examples of the electrolyte solution for lithium ion secondary batteries include non-aqueous electrolyte solutions prepared by dissolving an electrolyte (e.g. (justia.com)
  • Major negative electrode active materials for lithium ion secondary batteries are carbonaceous materials that can occlude and release lithium ions, and typical examples thereof include natural graphite, artificial graphite, and amorphous carbon. (justia.com)
  • Such lithium ion secondary batteries include highly active positive and negative electrodes. (justia.com)
  • The team first converted the amine substrates to lithium amides using n -BuLi. (chemistryviews.org)
Reaction12
  • One organic reaction involving aromatic amines is the Goldberg reaction. (newworldencyclopedia.org)
  • The reaction is carried out in the presence of a stronger base than the amine, such as pyridine, which removes HCl formed and shifts the equilibrium to the product side. (topperlearning.com)
  • Secondary and tertiary amines do not show this reaction. (topperlearning.com)
  • This reaction is used as a test for primary amines. (topperlearning.com)
  • The reaction of amines with benzenesulphonyl chloride in a different manner is used for the distinction of primary, secondary and tertiary amines. (topperlearning.com)
  • The reaction showed a broad scope and proved suitable for the α-cyanation of simple amines such as pyrrolidine or piperidine and for the α'-cyanation of a range of amines with an existing α-substituent. (chemistryviews.org)
  • To mitigate the competitive hydrolysis reaction, organic solvents such as amine-free, anhydrous DMF and DMSO may be used in combination with an aqueous buffer solution. (creativepegworks.com)
  • A New Reaction of Thionyl Chloride with a Carboxylic Acid in the Presence of a Tertiary Amine. (abcprofil.com)
  • The amine can also be used as the reaction solvent. (gelest.com)
  • The trimethylsilylation of amides and amines can be accomplished by a modification of this procedure wherein the reaction mixture is heated to reflux for 16 h. (gelest.com)
  • Through this reaction method, various amides were synthesized directly from aldehydes under mild conditions in high yields and short times. (ewha.ac.kr)
  • The amine functional groups may be metabolized in the liver to the acetylated and / or glucuronidated forms, or they may be oxidized to a hydroxylamine form, which undergoes further conversion via an acetylation reaction to form a N-acetoxy metabolite. (cdc.gov)
Bonds4
  • Transition-metal-free catalytic protocols for controlled reduction of amide functions using cheap and bench-stable hydrosilanes as reducing agents enable the selective reduction of unactivated C-O bonds in amides. (organic-chemistry.org)
  • Most aliphatic amines display some solubility in water, reflecting their ability to form hydrogen bonds. (newworldencyclopedia.org)
  • The C-H bonds at the unsubstituted α' site in these amines are usually less reactive than the C-H bond at the substituted α site, which makes this selectivity challenging to achieve. (chemistryviews.org)
  • Amide bonds were synthesized by an oxidative amidation in the presence of dibromoisocyanuric acid (DBI). (ewha.ac.kr)
Chapter5
Chemistry1
Solubility1
Triethylamine1
  • Examples of such amines are n-butylamine, 2-ethylbutylamine, 2-ethylhexylamine, trimethylamine and triethylamine. (allindianpatents.com)
Urea1
  • Oxidative removal of an aliphatic R group from a secondary or tertiary urea or amide nitrogen. (ethz.ch)
Acids3
  • The Preparation of Amides of Arylphosphonic Acids III. (wikipedia.org)
  • Triarylsilanols are reported as the first silicon-centred molecular catalysts for direct amidation of carboxylic acids with amines as identified after a screen of silanols, silanediols, disiloxanediols and incompletely condensed silsesquioxanes as potential homogeneous catalysts. (imperial.ac.uk)
  • Methyltrimethoxysilane [MTM, CH3Si(OMe)3] has been demonstrated to be an effective, inexpensive, and safe reagent for the direct amidation of carboxylic acids with amines. (imperial.ac.uk)
Urine1
  • 1989. Determination of aromatic amines in urine and serum. (cdc.gov)
Different structures2
  • Amides and amines have different structures and properties, so the distinction is chemically important. (newworldencyclopedia.org)
  • Amide-functionalised PLA of different structures (linear, telechelic, star-shaped etc. ) have been prepared using polyfunctional amines as initiators. (cnrs.fr)
Form1
Quaternary1
  • This result in the dislocation of the structure of the protein changes the secondary, tertiary and quaternary to the primary structure with negative charge. (wikibooks.org)
Residual1
  • This is possible because the pKa of diisobutylamine is higher than that for almost all residual amines that may be contained in a stream. (wikipedia.org)
Preparation2