• In vitro toxicity tests demonstrated that all the bioactive compounds showed far less toxicity against human erythrocytes. (scielo.org.za)
  • Therefore, the exploitation of this undervalued part of the plant can be a source of valuable bioactive compounds for food and/or pharmaceutical industries. (mdpi.com)
  • In conclusion, this study first investigated the chemical composition and potential pharmacological effects of the main chemical compounds in QZC, which will contribute to the revelation of bioactive compounds in QZC and provide evidence for clinical application. (hindawi.com)
  • And when we did, two thing were unanimous: first, that we had a hell of a crop of bows this year, and, second, that one model in particular was the clear winner for overall best new compound bow of 2023. (fieldandstream.com)
  • If you're about to fork over $1,500 or more for a new compound bow and accessories, we see it as our job to bring you a critique that's unbiased and laser-focused on one simple question: What are the best compound bows for 2023? (fieldandstream.com)
  • Int J Tuberc Lung Dis;27(2): 106-112, 2023 02 01. (bvsalud.org)
  • 27(2): 106-112, 2023 02 01. (bvsalud.org)
  • Results of a new 24-week interim analysis of data from the phase 2 pemvidutide trial, called MOMENTUM, were presented October 3 at the European Association for the Study of Diabetes (EASD) 2023 Annual Meeting by Aronne. (medscape.com)
  • Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells. (amrita.edu)
  • Quinolones inhibit the bacterial DNA synthesis [ 2 ], and there are several hypotheses to explain their mechanism of action. (hindawi.com)
  • Following the first successful synthesis of xenon compounds, synthesis of krypton difluoride (KrF2) was reported in 1963. (wikipedia.org)
  • In the treatment of obesity, the compoundAPD356 manufactured by ArenaPharmaceuticals Inc yielded good resultsin a recent phase 2 clinical trial.The randomized, double-blind trial tookplace over 12 weeks and included 469male and female obese patients. (pharmacytimes.com)
  • At present, most studies of QZC focus on its clinical applications with few analytical studies on its chemical compounds, causing poorly clarified chemical substances. (hindawi.com)
  • It's not going to be one compound for everybody," said Louis J. Aronne, MD, director of the Center for Weight Management and Metabolic Clinical Research, Weill-Cornell Medical College, New York. (medscape.com)
  • The effectiveness of SMC has been demonstrated in frame, we proceeded as follows for the selection of compounds, clinical trials conducted in the Sahel region (Bojang et al. (who.int)
  • Kabul, 14 June 2019 - World Health Organization (WHO) supported the Ministry of Public Health (MoPH) of Afghanistan to commemorate the world blood donor day with a series of activities including laying the foundation stones for 2 blood banks, each in Jamhuriate Hospital and Wazir Akbar Khan Hospital in Kabul. (who.int)
  • A 2019 British Medical Journal analysis determined that only about 2% of official bilateral and multilateral development aid is targeted at noncommunicable diseases, including breast and cervical cancer, The African region accounts for only 1% of world health expenditure, despite having 24% of the global disease burden, according to a 2019 report by the University of Washington's Institute for Health Metrics and Evaluation. (who.int)
  • Although the compounds have achieved great success in tumor therapy, the compounds still have a plurality of defects, for example, the treatment system does not have a stable composition ratio, has a slow metabolism in a body, has a short maximum excitation wavelength, and is easy to cause phototoxic side effects. (justia.com)
  • The study aim was to evaluate the cytotoxic activity, using the MTT test [3-(4,5-Dimethilthiazol-2-yl)-2,5-diphenil tetrazolium bromide], from the crude extract of Picrasma crenata (Pau Tenente) and its isolated compounds, quassin and parain, in culture of rat liver tumor cells (HTC). (scielo.br)
  • Cytotoxicity of extracts and compounds isolated from Croton echioides in animal tumor cell (HTC). (scielo.br)
  • Prasugrel is an ionic compound for which the measured log K ow increases over the environmental range. (janusinfo.se)
  • First released in early access on Steam in 2018, VR roguelite COMPOUND hit its 1.0 release on PC VR earlier this year and is now set to launch on Quest 2 for the first time next week on December 8th. (roadtovr.com)
  • Created by one-man indie developer Bevan "NotDead" McKechnie, Compound was originally released in early access on Steam in 2018 and saw slow but steady development right up to its 1.0 release on PC VR earlier this year. (roadtovr.com)
  • As of 2022, XeF8 has not been made, although the octafluoroxenate(VI) anion ([XeF8]2−) has been observed. (wikipedia.org)
  • Successive assays revealed that some compounds were endowed with a promising anti-proliferative effect against HCT116 cells, alone or stimulated by serotonin as a pro-inflammatory factor in order to mimick an inflamed model of cancer cell microenvironment. (amrita.edu)
  • Among all potent compounds, 10f exhibited promising safety profile in MTT assays and in hERG K + channel inhibition test. (figshare.com)
  • In chemistry, noble gas compounds are chemical compounds that include an element from the noble gases, group 18 of the periodic table. (wikipedia.org)
  • NIOSH considers soluble uranium compounds to be potential occupational carcinogens as defined by the OSHA carcinogen policy [29 CFR 1990]. (cdc.gov)
  • The revised IDLH for soluble uranium compounds is 10 mg U/m3 based on chronic toxicity data in animals [Wilson et al. (cdc.gov)
  • 1953]. [Note: NIOSH recommends as part of its carcinogen policy that the 'most protective' respirators be worn for soluble uranium compounds at concentrations above 0.05 mg U/m3. (cdc.gov)
  • Note: Blood volatile organic compound (VOC) results for styrene and toluene will not be publicly released for the NHANES 2011-2012 cycle (VOCWB_G, VOCWBS_G), because measured concentrations were significantly biased by elevated background levels that existed in the mobile examination centers (MEC) at the time the blood samples were collected. (cdc.gov)
  • and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors. (justia.com)
  • These concurrent outbreaks, associated with 1 compounding pharmacy, resulted in a product recall. (cdc.gov)
  • We describe 2 concurrent multistate outbreaks of fungal endophthalmitis associated with intraocular use of contaminated products labeled as sterile from a single compounding pharmacy. (cdc.gov)
  • The BBG implicated in the cases reported here was produced on August 23, 2011, at Franck's Compounding Lab (Franck's), a compounding pharmacy in Ocala, Florida, USA, which distributes products throughout the United States. (cdc.gov)
  • Ensuring safety and integrity of compounded medications is critical for preventing further outbreaks associated with compounded products. (cdc.gov)
  • Now there are nine different RPA ASTM International methods routinely used by the rubber industry to measure quality of raw rubber, state-of-mix differences for rubber compounds, predictions of downstream processability differences, etc. (rubbernews.com)
  • Of course, there are comparative advantages and dis- advantages for each of these RPA ASTM methods, depending on the quality differences of the raw rubber and vast quality differences among factory recipes, even among compounds that are used for the same purpose. (rubbernews.com)
  • With this study, we model effective magnetic interactions for the monolayer structures of a range of triangular lattice materials MX 2 ( M ={V,Mn,Ni}, X ={Cl,Br,I}). We also took the opportunity of such a larger study to benchmark two ab-initio methods used to extract effective S={3/2,5/2,1} spin models for real materials. (aps.org)
  • The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. (justia.com)
  • The stability of the materials with respect to competing binary compounds is also evaluated and details of the valence band maximum manifold splitting and effective masses are provided. (arxiv.org)
  • The first binary noble gas compounds were reported later in 1962. (wikipedia.org)
  • The compounds with aromatic N-heterocyclic substituents at the 4-position of pyrazolyl ring showed better antibacterial activity against the tested bacteria than other compounds with different patterns of substitution. (figshare.com)
  • Based on these charges (which can be obtained from the table), it makes sense that there are three ammonium molecules in the compound for every one phosphate molecule. (gradesaver.com)
  • Extremely low expenditure on health compounds the challenge. (who.int)
  • Toxicology 2002:181-2, 523-30. (cdc.gov)
  • Tp* 2 U(NBn), Tp* 2 U(N p -Tol), and Tp* 2 U(Ndetp), along with previously reported Tp* 2 U(NPh) and Tp* 2 U(NAd) (Ad = 1-adamantyl), readily undergo [2π+2π] cycloaddition with isocyanates and isothiocyanates to generate κ 2 -ureato and κ 2 -thioureato derivatives, respectively. (acs.org)
  • At the time, the researchers - led by Jerome Baudry, a molecular biophysicist at UAH - managed to identify over a hundred natural compounds (or close derivatives) with promising characteristics. (hpcwire.com)
  • After running through those 50,000 compounds, the researchers identified "125 natural products or close derivatives across plants, fungi, the sea and microbes" that possess chemical elements which bind to key proteins on the novel coronavirus, including compounds found in traditional medicines from around the world. (hpcwire.com)
  • Pursuant to section 68 or 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health conducted a screening assessment of four of five substances referred to collectively under the Chemicals Management Plan as the Furan Compounds Group. (canada.ca)
  • The ecological risks of the substances in the Furan Compounds Group in this assessment were characterized using the ecological risk classification of organic substances (ERC). (canada.ca)
  • Cut 2 pieces of wide, heavy-duty aluminum foil about 6 inches longer than the salmon fillet. (alaskaseafood.org)
  • Fold the foil sides and ends up (1-2 inches) to make a shallow pan around the salmon, leaving at least a 1-inch margin around the fish. (alaskaseafood.org)
  • That is why Prolimatech created the PK-2 thermal compound. (memoryc.com)
  • The PK-2 thermal compound is a high performance thermal bonding agent specially designed for easy application. (memoryc.com)
  • PK-2's core feature is its low viscosity, allowing for one to quickly and easily apply the thinnest coat of thermal compound possible. (memoryc.com)
  • A kinetic study of the gas phase thermal decomposition of 2-chloroethylsilicon compounds. (figshare.com)
  • The gas phase thermal decomposition of 2--chloroethyltrichloro-silane has been investigated in a static system between 356 and 417C at initial pressures of 12 - 138 mm. (figshare.com)
  • First, 2 and related compounds bind to an unusual, inactive conformation of the kinase which to the best of our knowledge has not been reported for other types of kinase inhibitors. (rcsb.org)
  • Sodium monofluoroacetate (SMFA, compound 1080): a literature review. (cdc.gov)
  • The mode of antibacterial action of 1c was also studied by scanning electron microscopy, which showed membrane disruption and cell lysis of the organisms during the exposure of the tested compound. (scielo.org.za)
  • Consistent with this classification, Kr, Xe, and Rn form compounds that can be isolated in bulk at or near standard temperature and pressure, whereas He, Ne, Ar have been observed to form true chemical bonds using spectroscopic techniques, but only when frozen into a noble gas matrix at temperatures of 40 K or lower, in supersonic jets of noble gas, or under extremely high pressures with metals. (wikipedia.org)
  • None of the six bulk samples of joint compounds contained asbestos, three contained minor silica and perlite contents, and two contained minor quantities of gypsum and talc with one containing a minor quantity of clay. (cdc.gov)
  • Six different off the shelf dry wall joint compounds were also examined. (cdc.gov)
  • The chosen IDLH is based on the statement by Patty [1963] that UO2(NO3)2×6H20 of respirable particle size and dusts and mists of UF6, UO2F2, and UCl4 were generally fatal to most laboratory species when exposed daily for 1 month at 20 mg/m3 [Wilson et al. (cdc.gov)
  • Note: You cannot use this feature on phrases or compound terms that are enclosed in quotation marks. (bvsalud.org)
  • Berries of Actinidia kolomikta ( A. kolomikta ) are known for high ascorbic acid content, but the diversity of phenolic compounds has been little studied. (mdpi.com)
  • By 1960, no compound with a covalently bound noble gas atom had yet been synthesized. (wikipedia.org)
  • Compound presentations may be observed more commonly after premature rupture of membranes, with preterm labor, with pelvic masses displacing the main fetal pole, or after inductions of labor involving floating presenting parts. (medscape.com)
  • drainage system in the Djoué compound · refurbishment of the estate workshops · full renovation of the air conditioning system · partial renovation of the main building façade · renovation of conference room ceiling. (who.int)
  • The all-purpose compound and thick pad material provide long-lasting braking performance. (nashbar.com)
  • Cut and place thick coin-sized pieces of compound butter on top of hot fish and let it melt. (alaskaseafood.org)
  • No grossly observable signs or symptoms were induced in mice, rats, guinea pigs, rabbits, or dogs following the first day of exposure to 20 mg/m3 of UF6 (13.5 mg U/m3), UO2F2 (15.5 mg U/m3), Ucl4 (12.5 mg U/m3), or UO2(NO3)2×H2O (9.5 mg U/m3) [Wilson et al. (cdc.gov)
  • In recent years, it has been demonstrated that this type of inheritance is also present in some type 1 and 2 families, previously considered the epitome of true dominant transmission. (karger.com)
  • Background: In China, traditional Chinese medicine (TCM) has been used to treat type 2 diabetes mellitus (T2DM) for centuries. (benthamscience.com)
  • xenon has been shown to produce a wide variety of compounds of the type XeOnX2 where n is 1, 2 or 3 and X is any electronegative group, such as CF3, C(SO2CF3)3, N(SO2F)2, N(SO2CF3)2, OTeF5, O(IO2F2), etc. (wikipedia.org)
  • HAMBURG, Germany ― The investigational incretin receptor agonist pemvidutide produced significant weight loss and other cardiometabolic benefits in a phase 2 randomized trial, adding a different type of "twincretin" to a growing mix of incretin-based weight-loss drugs in development that also offer additional benefits. (medscape.com)
  • Pemvidutide (Altimmune, Inc) is a long-acting "balanced" dual agonist of both glucagon-like peptide 1 (GLP-1) and glucagon that is in development for the treatment of obesity and nonalcoholic steatohepatitis (NASH) but not type 2 diabetes, as its effect on glucose is neutral. (medscape.com)
  • In contrast, the dual GLP-1-glucose-dependent insulinotropic polypeptide (GIP) agonist tirzepatide (Mounjaro, Lilly) has been approved for the treatment of type 2 diabetes. (medscape.com)
  • While about 20% to 25% of people with obesity also have type 2 diabetes, not everybody does. (medscape.com)
  • Compound presentations are rare obstetric events and often engender much anxiety in the care team. (medscape.com)
  • Compound presentations are more likely with obstetric interventions than with spontaneous events. (medscape.com)
  • Compound presentations preclude forceps applications orvacuum extraction. (medscape.com)
  • Now, the UAH researchers have provided a major update: a subset of those compounds are now undergoing experimental testing. (hpcwire.com)
  • Scientific hazard lists sometimes specify a chemical group (such as trimethyltin compounds) without a defined list of CASRNs. (pharosproject.net)
  • The chemical reactivity of the halogenoalkylsilicon compounds has been reviewed and the published quantitative work on the decomposition of 2-halogenoalkylsilicon compounds outlined. (figshare.com)
  • Asia-Pacific Journal of Chemical Engineering, 14 (2). (lancs.ac.uk)
  • All noble gases have full s and p outer electron shells (except helium, which has no p sublevel), and so do not form chemical compounds easily. (wikipedia.org)
  • Thus, the results demonstrate a first indication of the cytotoxic activity of compounds quassin and parain, adding an important social and economic value to them, and may have application in future research and in pharmaceutical industry. (scielo.br)
  • The news on the compounds comes amid a flurry of promising results from phase three vaccine trials. (hpcwire.com)
  • This results in an ionization energy low enough to form stable compounds with the most electronegative elements, fluorine and oxygen, and even with less electronegative elements such as nitrogen and carbon under certain circumstances. (wikipedia.org)
  • An analogous study has been carried out on 2-chloroeth1-dimethlphenylsilane between 236 and 390C. (figshare.com)
  • Theoretical study of the discrimination between O(2) and CO by myoglobin. (lu.se)
  • Specifically, he predicted the existence of krypton hexafluoride (KrF6) and xenon hexafluoride (XeF6), speculated that XeF8 might exist as an unstable compound, and suggested that xenic acid would form perxenate salts. (wikipedia.org)
  • Starting from HTS hit aminopyrazine 2, compounds with improved activity were identified using structure-based design. (rcsb.org)
  • Perfect for classrooms, party favors, stocking stuffers, Play-Doh playset refills, or a fun rainy day activity, this versatile toy set lets kids ages 2 and up squish and shape their imaginations' silliest ideas in a creative and classic arts and crafts activity. (toysrus.ca)
  • A series of novel teraryl oxazolidinone compounds was designed, synthesized, and evaluated for their antimicrobial activity and toxicities. (figshare.com)
  • Besides, all these compounds were proven to have potential pharmacological activity in the treatment of RA based on network pharmacology analysis. (hindawi.com)
  • McKechnie says the Quest version of Compound includes the full contents of the PC VR version, except for leaderboards and achievements. (roadtovr.com)
  • After the initial 1962 studies on XeF4 and XeF2, xenon compounds that have been synthesized include other fluorides (XeF6), oxyfluorides (XeOF2, XeOF4, XeO2F2, XeO3F2, XeO2F4) and oxides (XeO2, XeO3 and XeO4). (wikipedia.org)
  • Those 35 compounds - as-yet unenumerated - are now undergoing first-batch testing at the University of Tennessee Health Science Center's Regional Biocontainment Laboratory (UTHSC RBL). (hpcwire.com)
  • An automatic method to generate force-field parameters for hetero-compounds. (lu.se)
  • Additionally, MoPH and WHO organized two blood donation drives, each in Central Blood Bank and in United Nations (UN) Compound in Kabul. (who.int)
  • Still, when you get the chance to shoot all of 2023's new bows side-by-side, as we do-thousands of arrows over the course of several days-you notice subtleties in performance that reveal which are truly the best compound bows of the year. (fieldandstream.com)