Seasonal weather changes. Medical search. Frequent questions

Soaring temperatures, summer storms, and drought conditions can all contribute to extreme weather. (cdc.gov)
Outfit your team to weather the storms with cold weather-related gifts like gloves, beanies, and puffer jackets. (geiger.com)
But the season can also bring weather hazards, such as strong storms with whipping winds, early season snows, and floods. (climate.gov)

We offer a total of 50-prototypes (time-series scenarios) and 11 percentiles, making this the first calibrated, daily resolution seasonal probabilistic forecast offering that we are aware of. (confex.com)
Therefore, we have expanded our efforts to reconstruct our calibrated Seasonal Probabilistic Forecast backwards to January 1981. (confex.com)
In an Australian breakthrough, we are working with the Bureau of Meteorology to transform weather forecast data and tailor it for farmers and agribusiness in a way they've never had before. (www.csiro.au)
This information can be as simple as the weather forecast or as complex as a crop yield forecast. (www.csiro.au)
We hear many times that the local weather forecast "doesn't represent what happens in my paddock. (www.csiro.au)
We ingest data from individual on-farm weather stations and use this to continually 'learn' how the forecast differs to what farmers experience on their farms. (www.csiro.au)
These AI techniques are unavoidable to make sense of the rapidly increasing data deluge and to respond to the challenging new demands in Weather Forecast (WF), Climate Monitoring (CM) and Decadal Prediction (DP). (mdpi.com)
Be prepared and check the weather and marine forecast regularly. (nps.gov)
Loading weather forecast. (nps.gov)
Although it's difficult to predict how bad an allergy season will be, paying attention to your local weather forecast can help. (medlineplus.gov)

Medium-range forecasting is mainly an initial condition problem, while predictability at the long (seasonal) range is strongly dependent on the slow internal variability of the climate system e.g. varying sea surface temperatures. (ecmwf.int)
With this weather station you will be able to explore: Seasons, Rainfall, Wind speed,Temperatures, and Moon phases. (bellalunatoys.com)
This high elevation means the city experiences cooler temperatures and more intense weather conditions compared to lower elevation areas. (dreamcoloradosprings.com)
During this time, the weather is cool and pleasant, with temperatures ranging from 10 to 28 degrees Celsius. (thecorinthianspune.com)
We'll likely see temperatures remain slightly below seasonal averages with highs returning to near or even slightly above average today before trending a little bit warmer over the weekend. (abc4.com)
Looks like this system could bring a decent chance of wet weather for the northern half of the state while temperatures ease down to slightly below averages. (abc4.com)
Sweater Weather is a comforting blend crafted to harness all the fall vibes while the temperatures slowly cool off and eventually allow you to slip into your favorite, old sweaters. (yieldcoffee.com)
In addition, significant winter weather occurred throughout the season, including a major blizzard that struck the Northeastern United States at the end of January, another blizzard that affected much of the Northern United States days later in early February, and several significant snow events paired with very frigid temperatures for much of February. (wikipedia.org)
they were less likely to walk in cloudy weather than in sunny weather and during high temperatures than during moderate temperatures. (cdc.gov)
Adults were more likely to engage in vigorous PA in the fall and winter than in the summer, during cloudy weather than during sunny weather, and at low temperatures than at moderate temperatures. (cdc.gov)

A dog named Fred comes over to investigate atop a wall on the plaza of the Lincoln Memorial on Presidents Day, Feb. 15, 2021, in Washington D.C. Like humans, dogs can suffer from seasonal allergies. (weather.com)
She adds that if one or both parents suffer from seasonal allergies, a child is more likely to have them too. (wate.com)
But if you're one of the many people who suffer from seasonal allergies, those pretty trees and plants may make you feel worse, not better. (medlineplus.gov)

While decisions based on short and medium-range forecasts can support such actions, utilising information derived from the sub-seasonal to seasonal range (S2S) can further extend the lead time, and provide the opportunity to implement additional (low-cost) measures well in advance (e.g. (ecmwf.int)
Seasonal forecasts have been demanded by clients in the B2B (Business-to-Business) space for decades. (confex.com)
While the bulk of our clients still prefer a deterministic outlook, we have begun to provide probabilistic offerings at The Weather Company/IBM to satisfy the growing need for quantitative risk assessment of seasonal forecasts. (confex.com)
Founded and trusted since 1818, the annually published Farmers' Almanac has remained remarkably accurate in predicting long-range weather forecasts. (geiger.com)
Though most known for their trusted weather forecasts, the Farmers' Almanac is far from just that. (geiger.com)
We have developed a complex algorithm to transform the Bureau of Meteorology's weather forecasts into one that is more accurate for specific locations. (www.csiro.au)
We can then provide personalised local weather forecasts. (www.csiro.au)
Keep individuals informed about upcoming weather changes by engaging in regular discussions about forecasts. (shadow-project.org)
Utilize visual aids or tactile cues to convey weather forecasts effectively. (shadow-project.org)
Learn more about the climate in the Apostle Islands and explore sources for current weather information, including Lake buoys and Marine Forecasts. (nps.gov)

As the seasons change, so does the weather in Colorado Springs. (dreamcoloradosprings.com)
Not all researchers agree that certain weather or seasons cause or are linked to RA pain or stiffness. (medicalnewstoday.com)
If the incidence of LD depends on local weather, the baseline rate of LD might be extremely low year-round in some locations and during specific seasons in other locations. (cdc.gov)
Background: As in northern Finland and Sweden, the Arctic and subarctic environments of Alaska provide a hazardous work setting, exacerbated by great distances, seasonal darkness, very cold waters, high winds, often brief hunting and fishing seasons, and high icing potential. (cdc.gov)

Intuitively, this makes sense given the existence of seasonal affective disorder and the tendency to associate winter with depression. (wikipedia.org)

So, what does the Farmers' Almanac predict the weather has in store for 2021-2022? (geiger.com)
U.S. RSV epidemics typically follow seasonal patterns, peaking in December or January (6,7), but the COVID-19 pandemic disrupted RSV seasonality during 2020-2022 (8). (cdc.gov)

In fact, some of the targets of the centre for the coming years include the S2S predictability of high impact weather up to two weeks ahead, as well as the predictions of large-scale patterns and regime transitions up to four weeks ahead. (ecmwf.int)
Then the work will investigate the predictability of the previously identified large-scale patterns in current numerical weather prediction (NWP) models. (ecmwf.int)
For one, MJO will modulate the westerlies, cause amplification and retrogression and cause some exciting and possibly amazing weather patterns. (mammothweather.com)
From blooming flowers and warm days to crisp leaves and chilly nights, Colorado Springs' weather patterns are a sight to behold. (dreamcoloradosprings.com)
It's clear that Colorado Springs experiences a wide range of weather patterns throughout the year. (dreamcoloradosprings.com)
The mountains can block or redirect storm systems , leading to unpredictable weather patterns and occasional extreme conditions. (dreamcoloradosprings.com)
Colorado Springs sits at an elevation of over 6,000 feet , which greatly affects its weather patterns. (dreamcoloradosprings.com)
The higher altitude also brings about changes in air pressure, humidity levels, and wind patterns, all of which contribute to the unique weather transitions in Colorado Springs. (dreamcoloradosprings.com)
During the spring and fall months, the higher elevation of Colorado Springs plays a significant role in the city's seasonal weather patterns. (dreamcoloradosprings.com)
The impact of elevation on weather patterns is also evident in the temperature fluctuations that occur in Colorado Springs. (dreamcoloradosprings.com)
This consultation uses dispersion modeling and seasonal weather patterns to identify optimal sampling locations. (cdc.gov)
Overall, we observed substantial geographic and seasonal patterns in human exposure to animals that could be sources of zoonotic disease. (cdc.gov)

By using satellite altimeter observations and the eddy-permitting Estimating the Circulation and Climate of the Ocean, Phase II (ECCO2), the seasonal variation of eddy kinetic energy (EKE) along the East Australian Current (EAC) is investigated. (mdpi.com)
The seasonal variation of baroclinic instability is opposite to the barotropic instability variation, but of a much smaller magnitude. (mdpi.com)
We sought to describe the frequency of human exposure to these animals and the seasonal and geographic variation of these exposures in Bangladesh. (cdc.gov)

There are many types of seasonal businesses which are very lucrative during their seasonal highs. (awesomecx.com)

Visit CDC's website at emergency.cdc.gov for more information about preparing for, responding to, and recovering from potential hurricanes, extreme heat, wildfires, and other natural disasters and severe weather this summer. (cdc.gov)
Jaci's research has spanned tropical oceanography, climate projections including impacts on natural disasters like bushfires, fisheries, high resolution ocean defence tools, and seasonal atmospheric processes in Australia. (www.csiro.au)
Our team liaises with experts at CDC to produce content and trainings that cover a host of emergency preparedness and response topics, such as influenza, severe weather and natural disasters, and infectious disease outbreaks. (medscape.com)
Risk factors such as changes in land use, seasonal migration, international travel, extreme weather, and natural disasters, and the use of azole antifungal agents in large-scale agriculture are believed to underlay many of the increases in community-acquired fungal infections. (cdc.gov)

This time of year, many of us are sniffling, sneezing and itching due to seasonal allergies. (weather.com)
Seasonal allergies are brought on by factors only present during specific times of the year. (weather.com)
While humans will typically experience sneezing plus a runny nose and eyes due to seasonal allergies, dogs more often have itching and red skin - though they can have symptoms similar to humans as well. (weather.com)
Besides itching, other signs that your furry friend may have seasonal allergies include licking, biting at the skin and face rubbing. (weather.com)
Recurring ear infections can also be a sign of seasonal allergies in dogs. (weather.com)
Testing for seasonal allergies can help determine the specific trigger after other causes have been eliminated. (weather.com)
If you think your dog has seasonal allergies, be sure to work with your veterinarian to determine the cause and pursue proper treatment for managing itch and other symptoms early on so your pup won't be slowed down,' Bonilla said. (weather.com)
As the autumn sunbathes Texoma, a familiar foe returns with a vengeance, seasonal allergies. (kxii.com)
What triggers seasonal allergies? (medlineplus.gov)
Pollen is harmless, but if you have seasonal allergies, your body mistakes the pollen for something dangerous and tries to attack it. (medlineplus.gov)
Unlike colds, seasonal allergies usually last longer than a week or two. (medlineplus.gov)
Providers can also diagnose seasonal allergies based on when your symptoms develop. (medlineplus.gov)
Mold spores often cause seasonal allergies during the spring, summer, and fall. (medlineplus.gov)
Seasonal allergies often run in families. (medlineplus.gov)
Many people with seasonal allergies also have asthma. (medlineplus.gov)
Seasonal allergies-also known as allergic rhinitis or hay fever-may affect nearly one in six Americans. (medlineplus.gov)

I ordered three different coffees last year (Sweater Weather, Honduras, and Brazil) and loved them all so I just had to get more! (yieldcoffee.com)
But this Sweater Weather blend from @yieldcoffee warms you up and brings our all the Fall feelings. (yieldcoffee.com)

We've been collecting general weather data for Crondall since February 2006, but in late January 2020 added a solar sensor to allow us to start tracking sunshine hours, solar energy and Evapotranspiration. (crondallweather.co.uk)

This is a significant increase from the colder winter months, but it's important to note that springtime can also bring unpredictable weather. (dreamcoloradosprings.com)
People may be less active in colder weather, which worsens symptoms. (medicalnewstoday.com)
Weather in the colder season increases the prevalence of afflictions such as pneumonia and hypothermia, which largely proceeds from the minimal amount of sunlight exposure in the wintertime. (wikipedia.org)

Seasonal/environmental allergy testing can be performed in dogs by either skin testing or blood testing,' Burkett said. (weather.com)
If you're looking for ways to manage your seasonal allergy symptoms, including congestion, a few products can help you breathe more easily. (khon2.com)
For seasonal allergy sufferers, rain is usually thought of as a friend-it washes the pollen out of the air. (medscape.com)

Nobody knows the hazards of this dynamic season more than NOAA's National Weather Service. (climate.gov)
But don't let the sunny days and warm nights fool you-summer holds significant weather hazards. (climate.gov)

Inside INdiana Business) - The COVID-19 pandemic is having an effect on virtually every industry, but as the weather continues to warm up, companies relying on seasonal workers are starting to feel the strain even more. (wishtv.com)
From spring's unpredictable weather to summer's warm days and fall's changing leaves, each season brings its own unique charm to the city. (dreamcoloradosprings.com)
However, this meteorological winter was the 19th-warmest of the past 120 winters over the Contiguous United States, largely due to persistent warm weather in the Western United States. (wikipedia.org)
LD risk increases when weather is warm and humid. (cdc.gov)
With warm weather, we found a dose-response relationship between relative humidity and the odds for LD. (cdc.gov)
Thus, suspicion for LD should increase when weather is warm and humid. (cdc.gov)
In contrast, warm and humid weather tends to support pathogen survival, growth, and the potential for aerosol exposures, increasing disease risk ( 1 , 13 , 19 ). (cdc.gov)
Warm weather has been known to initiate episodes, with several cases reporting photo-induced pompholyx. (medscape.com)

Lifestyle Expert Richard Cazeau ushers in the cooler weather with playful gear designed to make the next few months more fun. (cp24.com)

cancelled only in case of severe weather. (lewisginter.org)

As it happens, the seasonal shifts caused by the tilt of the earth's axis and the earth's orbit around the sun have a known period of one year, and the sun's stimulation at any given location has a known phase. (judithcurry.com)
We'll place a special emphasis on the sensory aspects that play a crucial role in these challenges, and we'll explore the profound effects of shifts in outerwear, weather, food, and holidays on individuals with sensory sensitivities. (shadow-project.org)
This could include simplified visual charts or tactile representations to indicate impending weather shifts. (shadow-project.org)
Seasonal shifts often bring about alterations in dietary options and culinary routines, impacting daily schedules. (shadow-project.org)

The prime season is different for the various seasonal industries but is around the same time each year. (awesomecx.com)

Weather and climate extremes can have serious impacts on our society, ranging from the destruction of crops and infrastructure, to fatalities. (ecmwf.int)

Why does seasonal change affect my rheumatoid arthritis symptoms? (medicalnewstoday.com)
The researchers also note that the findings could be biased by the participants' prior beliefs, as people who join this type of study may already believe that there is an association between their symptoms and the weather. (medicalnewstoday.com)
They could not explain why there was no significant link between RA symptoms and weather in younger or older adults. (medicalnewstoday.com)
They speculate that cold weather could cause stiffness in the muscles around the joints, which could make arthritis symptoms worse. (medicalnewstoday.com)
When working in a cold environment for a long period of time: a) Learn the signs and symptoms of cold weather illnesses and injuries. (cdc.gov)

Over the course of 6 months, most people reported a modest increase in pain or discomfort when the weather was humid or windy or when atmospheric pressure was low. (medicalnewstoday.com)

Seasonal RSV epidemics were defined as the weeks during which the percentage of PCR test results that were positive for RSV was 3% (9). (cdc.gov)

Weather fluctuations can significantly disrupt daily routines for neurodivergent individuals. (shadow-project.org)

In this article, we will take a comprehensive look at the seasonal transitions that occur in Colorado Springs. (dreamcoloradosprings.com)
Whether you're planning a trip to Colorado Springs or simply curious about its weather, this article will provide valuable insights into the spring and fall weather transitions in this beautiful city. (dreamcoloradosprings.com)
As spring transitions into summer, the weather becomes warmer and more stable. (dreamcoloradosprings.com)

Mild dry weather for the first full week of October. (9news.com)

Whether it's winterizing for cold weather or preparing for the rainy season, the maintenance is tailored to the specific challenges presented by the weather. (fakesunglasseswholesale.com)
A quasi-permanent phenomenon referred to as the polar vortex may have been partly responsible for the cold weather. (wikipedia.org)
Hazard alert: working in cold weather - a chilling danger. (cdc.gov)
During the winter, construction workers face a natural hazard - cold weather. (cdc.gov)

High pressure is in control, and we'll get some gorgeous weather to round out the workweek and move into the weekend. (abc4.com)

However, strong evidence indicates that weather, particularly temperature and humidity, drive the summer spike in incidence ( 11 , 12 , 15 , 16 ). (cdc.gov)
We used the System for Observing Play and Recreation in Communities to examine the association between variations in natural elements (ie, season, weather, and temperature) and adults' use of a rail-trail in South Carolina (2006-2009). (cdc.gov)
We examined the effects of seasonal differences and variations in weather and temperature on adults' trail use. (cdc.gov)
to assess trail user demographics and behaviors (determined by trained observers) and to record variations in season, weather, and temperature. (cdc.gov)
The observers also coded the season, weather, and temperature during each observation period. (cdc.gov)
Logistic regression models were used to compare adults observed walking versus engaging in vigorous PA by season, weather, and temperature. (cdc.gov)
Studies indicate that variations in season, weather, and temperature may influence physical activity (PA) behavior (1,2) such as trail use. (cdc.gov)
Trained observers used the 7-day version of the System for Observing Play and Recreation in Communities (SOPARC) (7) to assess trail user demographics and behaviors (determined by trained observers) and to record variations in season, weather, and temperature. (cdc.gov)

Other autoimmune conditions, such as Sjögren's, also seemed to flare during extreme weather in the summer and winter. (medicalnewstoday.com)
Research on seasonal effects on suicide rates suggests that the prevalence of suicide is greatest during the late spring and early summer months, despite the common belief that suicide rates peak during the cold and dark months of the winter season. (wikipedia.org)
Specifically, Bridges found that in the 1970s "about 47% of the total variances can be explained by the seasonal components" within that given decade (with more suicides in spring/summer). (wikipedia.org)
One international study on seasonal effects on suicide rates involving 20 countries showed an early summer peak in suicides. (wikipedia.org)
The ECCO2 result reveals that the intra-seasonal EKE is mainly concentrated in the upper 500 m layer, and shows a prominent seasonal cycle, strong in austral summer and weak in austral winter. (mdpi.com)

And this last year, that program was put into a lottery system where everyone across the country would apply for those seasonal employees. (wishtv.com)
NOAA's National Weather Service (NWS) wants you to be prepared for hazardous weather year-round. (climate.gov)
Winter (December 1): On average, weather-related vehicle crashes kill 6,253 people and injure more than 480,000 each year, according to the Department of Transportation. (climate.gov)
Discover how to keep your dog safe and happy throughout the year, whatever the weather. (dogstrust.org.uk)
Bridges's study focused on seasonal effects on suicide risk by examining the monthly distribution of suicides in the 1970s, 1980s, and 1990s via a "harmonic time series model" with six observable harmonic cycles within each consecutive year. (wikipedia.org)
This review explores the concept of seasonal maintenance packages and their significance in maintaining apartment buildings throughout the year. (fakesunglasseswholesale.com)

CAFE's goal is to improve predictability at sub-seasonal timescales by developing an interdisciplinary network of highly trained researchers. (ecmwf.int)

Once all the snow has melted, and the weather warms up, their season is over. (awesomecx.com)
Many ice cream shops close down completely In the northern states in the winter until the weather warms up again. (awesomecx.com)

It is critical to consider the seasonal winds as well as the sampling locations to optimize sampling. (cdc.gov)

Use this Seasonal Wooden Weather Station from Tender Leaf Toys to track the sunshine and rain, explore the wonders of weather and decide what to wear each day. (bellalunatoys.com)

This S2S (or extended ) time range sits between medium-range day-to-day weather forecasting and the seasonal range and beyond (or long range ). (ecmwf.int)
During a park closure due to weather, park offices will be closed, snow removal operations may be delayed, and the Meyers Beach area will be closed, including the ice caves (if accessible at that time). (nps.gov)
A season is based on the actual calendar dates or a specific time based on weather, events, or holidays. (awesomecx.com)
During the 2014-15 winter season, Boston broke its all-time official seasonal 107.6-inch (2.73-meter) snowfall record from the winter of 1995-96, with a total snowfall record of 108.6 inches (2.76 m) as of March 15, 2015. (wikipedia.org)

We are scientists in the ECMWF Diagnostics team working on the sub-seasonal predictability of extreme weather over Europe, within the EU-funded CAFE project . (ecmwf.int)
The Mediterranean is often affected by extreme weather events (e.g. torrential rainfall, cyclones, and droughts). (ecmwf.int)
Extreme weather poses serious health risks, causing illnesses, injuries and sometimes death. (cdc.gov)

Seasonal maintenance packages typically include a well-defined schedule of inspections and checklists. (fakesunglasseswholesale.com)

DeNardin said, before the program switched to a lottery format, the company had brought in the same group of 85 seasonal migrant workers for over a decade. (wishtv.com)
Even if the company was able to secure seasonal migrant workers through the federal program, DeNardin says those workers would not be able to come to the United States because of President Donald Trump's temporary immigration suspension. (wishtv.com)
While seasonal agriculture workers are exempt from the travel ban through the H-2A program, DeNardin says those in the H-2B program are not exempt. (wishtv.com)
Greece's Court of Auditors (Ελεγκτικό Συνέδριο) ruled as "unconsitutional" the upcoming cuts in pensons, the scraping of Christmas, Eastern and Vacation bonuses, the decreases to jobless allowances for seasonal workers, the raising of age criteria for the social benefit of EKAS and thus for all those with low income. (keeptalkinggreece.com)
Seasonal workers in tourism, construction and agriculture will be at risk to lose their allowances as of 01.01.2013. (keeptalkinggreece.com)
According to new regulations issued by OAEED (Greek Unemployment Agency) seasonal workers will be able to receive allowances only for 450 days and thus retrospective since 01.01.2009. (keeptalkinggreece.com)

Large, high quality studies into the effects of weather on RA are sparse. (medicalnewstoday.com)
According to Bridges, recent research from industrialized countries (including Finland, Sweden, Australia, New Zealand, England, and Wales) has provided enough information to show a decrease in seasonal effects on suicide rates over the past few decades. (wikipedia.org)

So whether you're visiting during spring or fall, be prepared for the possibility of varying weather conditions and enjoy all that Colorado Springs has to offer. (dreamcoloradosprings.com)
Seasonal maintenance packages are a proactive approach to ensuring that apartments are well-prepared for the challenges of changing weather conditions. (fakesunglasseswholesale.com)
Seasonal maintenance packages are an effective strategy for ensuring that apartments are well-prepared for the challenges of changing weather conditions. (fakesunglasseswholesale.com)
To establish the risk for LD across season, location, and weather conditions, we combined patient-level data on hospitalizations for pneumonia and LD from 26 US states with local weather data. (cdc.gov)

ECMWF, even though focusing on medium-range forecasting, is actively involved in this effort providing a variety of products extending even beyond seasonal scales. (ecmwf.int)

Farmers, agronomists, agribusiness, suppliers, banks and others all need to make decisions that depend on the weather and climate. (www.csiro.au)

Seasonal packages prioritize the maintenance and cleaning of HVAC systems to optimize energy efficiency and indoor air quality. (fakesunglasseswholesale.com)

As noted in a study led by Timo Partonen and colleagues, "There was a seasonal effect on suicide occurrence among the study population in Finland, and the risk of suicide was highest in May and lowest in February over the study period"…males with an incidence of 42.56 (N=21,622) and females with an incidence of 10.86 (N=5847). (wikipedia.org)

You'll have to order your copies to get the extended reports but read on for a sneak preview of what you can expect as well as fun weather prediction gifts. (geiger.com)

Seasonal Laborers may work up to six months (1040 hours) during the vegetation growing season and weather sensitive street and surface water maintenance activities between April/May and September/October. (shorelineareanews.com)

Enhance your understanding and appreciation of the Garden with this specialized garden walk featuring seasonal aspects of the collection. (lewisginter.org)

Patches for weathers mods don't require permission, feel free to make them and share them. (nexusmods.com)
However, there are circumstances in which a particular type of wet weather event can make things much worse: thunderstorms. (medscape.com)

Diseases2

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Psychiatry and Psychology1

Phenomena and Processes18

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science2

Named Groups1

Health Care23

Geographicals4

Storms3

Forecast10

Temperatures10

Suffer from seasonal allergies3

Forecasts10

Seasons4

Affective disorder1

20222

Patterns12

Variation3

Highs1

Natural disasters4

Allergies16

Sweater Weather2

20201

Colder3

Allergy3

Hazards2

Warm8

Cooler1

Severe weather1

Shifts4

Various seasonal1

Climate extremes1

Symptoms5

Atmospheric1

Epidemics1

Fluctuations1

Transitions3

Mild1

Cold weather4

Workweek1

Temperature8

Summer5

Year6

Trained researchers1

Warms2

Winds1

Sunshine1

Time4

Extreme weather3

Typically1

Workers6

Effects2

Conditions4

Scales1

Farmers1

Optimize1

Incidence1

Prediction1

Work1

Appreciation1

Make2