Screen anticancer drug in vitro. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Tumor Cells, Cultured MCF-7 Cells HT29 Cells HCT116 Cells HeLa Cells Cell Line Hep G2 Cells HL-60 Cells K562 Cells Mitochondria KB Cells Cells, Cultured Spheroids, Cellular Jurkat Cells

Organisms7

Mice, Nude Taxus Mice, Inbred BALB C Mice, SCID Saccharomyces cerevisiae Catharanthus Mice, Inbred C57BL

Diseases14

Neoplasms Breast Neoplasms Colonic Neoplasms Leukemia P388 Neoplasms, Experimental Lung Neoplasms Leukemia L1210 Ovarian Neoplasms Adenocarcinoma Prostatic Neoplasms Melanoma, Experimental Neovascularization, Pathologic Melanoma Liver Neoplasms

Chemicals and Drugs131

Antineoplastic Agents Doxorubicin Antineoplastic Agents, Phytogenic Antibiotics, Antineoplastic Cisplatin Drug Carriers Ellipticines Camptothecin P-Glycoprotein Etoposide Paclitaxel DNA Topoisomerases, Type II Prodrugs Enzyme Inhibitors Topoisomerase I Inhibitors Daunorubicin Plant Extracts Platinum Nanocapsules Caspases Mitomycin Organoplatinum Compounds Fluorouracil Mitoxantrone Antimetabolites, Antineoplastic Drugs, Investigational Multidrug Resistance-Associated Proteins DNA Intercalating Agents Proto-Oncogene Proteins c-bcl-2 Caspase 3 DNA Adducts Neoplasm Proteins RNA, Small Interfering ATP-Binding Cassette Transporters Small Molecule Libraries Topoisomerase Inhibitors Xanthones Tubulin Modulators Topoisomerase II Inhibitors Tumor Suppressor Protein p53 Adjuvants, Pharmaceutic DNA Topoisomerases, Type I Coordination Complexes Antineoplastic Agents, Alkylating Anticarcinogenic Agents RNA, Messenger Razoxane Liposomes Vinblastine Teniposide DNA-Binding Proteins Histone Deacetylase Inhibitors Bleomycin Triazines Pyrazines Triterpenes Vinca Alkaloids Topotecan Depsipeptides Reactive Oxygen Species Protein Kinase Inhibitors Boronic Acids Chlorambucil Benzoquinones Polyethylene Glycols Angiogenesis Inhibitors Proteasome Inhibitors Naphthoquinones Amsacrine Rhodamine 123 Indoles Piperazines Nimustine Vincristine DNA, Neoplasm Floxuridine Taxoids Protein-Serine-Threonine Kinases Biological Products Thiazoles Micelles Poly(ADP-ribose) Polymerases Anthracyclines Aziridines Platinum Compounds Dioxoles Hydroxamic Acids Radiation-Sensitizing Agents Pyrimidines Caspase 9 Curcumin Nuclear Proteins Organoselenium Compounds P-Glycoproteins Deoxycytidine bcl-2-Associated X Protein Cross-Linking Reagents Cell Cycle Proteins Sesquiterpenes HSP90 Heat-Shock Proteins Stilbenes Polymers Podophyllotoxin Tetrahydroisoquinolines Enediynes Methotrexate Oligopeptides Sulfonamides Glutathione Apoptosis Regulatory Proteins Transcription Factors Anthraquinones Tubulin Tetrazolium Salts Oxides Dianhydrogalactitol Lactams, Macrocyclic Carrier Proteins Caspase 7 Polyglycolic Acid Olivomycins Antimitotic Agents Indazoles Polonium Antigens, CD95 Proto-Oncogene Proteins c-akt Flavonoids Macrolides Cytochromes c Isoquinolines

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Drug Screening Assays, Antitumor Drug Delivery Systems Drug Carriers Xenograft Model Antitumor Assays Inhibitory Concentration 50 Drug Evaluation, Preclinical Drug Design Drug Discovery High-Throughput Screening Assays Nanocapsules Molecular Targeted Therapy Blotting, Western Neoplasms, Experimental Neoplasm Transplantation Flow Cytometry Models, Biological Clinical Trials, Phase I as Topic Models, Molecular Transfection Transplantation, Heterologous Antineoplastic Combined Chemotherapy Protocols Phytotherapy Clinical Trials as Topic Reverse Transcriptase Polymerase Chain Reaction Drug Approval Tumor Stem Cell Assay Tumor Burden Molecular Docking Simulation Electrochemotherapy Gene Knockdown Techniques Melanoma, Experimental Gene Expression Profiling Two-Hybrid System Techniques Chromatography, High Pressure Liquid Immunoblotting Microscopy, Fluorescence Magnetic Resonance Spectroscopy

Phenomena and Processes46

Drug Resistance, Neoplasm Apoptosis Cell Survival Cell Proliferation Inhibitory Concentration 50 Molecular Structure Drug Resistance, Multiple Drug Synergism Dose-Response Relationship, Drug Cell Cycle DNA Damage Gene Expression Regulation, Neoplastic Signal Transduction Structure-Activity Relationship DNA Adducts RNA Interference Cell Death Drug Resistance Genes, MDR Cell Division Base Sequence Protein Binding Cell Cycle Checkpoints Particle Size Transfection Time Factors Down-Regulation Amino Acid Sequence DNA Repair Phenotype Phosphorylation Enzyme Activation Drug Interactions G-Quadruplexes G2 Phase Binding Sites DNA Fragmentation Cell Growth Processes Gene Expression Membrane Potential, Mitochondrial Up-Regulation Kinetics Molecular Conformation Biological Transport Mutation Stereoisomerism

Disciplines and Occupations5

Drug Design Drug Discovery Nanomedicine Pharmacogenetics Chemistry, Pharmaceutical

Anthropology, Education, Sociology and Social Phenomena3

Drug Approval National Cancer Institute (U.S.)National Institutes of Health (U.S.)

Technology, Industry, Agriculture8

Nanoparticles Nanomedicine Nanocapsules Liposomes Nanostructures Polyethylene Glycols Polymers Polyglycolic Acid

Information Science4

Molecular Sequence Data Base Sequence Amino Acid Sequence Molecular Docking Simulation

Health Care4

Clinical Trials, Phase I as Topic Clinical Trials as Topic National Cancer Institute (U.S.)National Institutes of Health (U.S.)

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Technology, Industry, Agriculture Information Science Health Care

Antineoplastic Agents Drug Screening Assays, Antitumor Cell Line, Tumor Neoplasms Doxorubicin Drug Resistance, Neoplasm Apoptosis Antineoplastic Agents, Phytogenic Antibiotics, Antineoplastic Drug Delivery Systems Cell Survival Cisplatin Drug Carriers Tumor Cells, Cultured Ellipticines Xenograft Model Antitumor Assays Cell Proliferation Inhibitory Concentration 50 Mice, Nude Camptothecin Molecular Structure Drug Resistance, Multiple P-Glycoprotein Drug Evaluation, Preclinical Drug Design Etoposide Paclitaxel Drug Synergism Dose-Response Relationship, Drug DNA Topoisomerases, Type II Drug Discovery Cell Cycle Prodrugs Enzyme Inhibitors DNA Damage Topoisomerase I Inhibitors Daunorubicin Nanoparticles Nanomedicine Plant Extracts High-Throughput Screening Assays Gene Expression Regulation, Neoplastic Platinum Nanocapsules Breast Neoplasms Signal Transduction Colonic Neoplasms Caspases Molecular Sequence Data Mitomycin Structure-Activity Relationship Organoplatinum Compounds Fluorouracil Molecular Targeted Therapy Mitoxantrone Antimetabolites, Antineoplastic Drugs, Investigational Multidrug Resistance-Associated Proteins DNA Intercalating Agents Proto-Oncogene Proteins c-bcl-2 Caspase 3 DNA Adducts Neoplasm Proteins RNA, Small Interfering RNA Interference MCF-7 Cells HT29 Cells ATP-Binding Cassette Transporters HCT116 Cells Leukemia P388 Cell Death Small Molecule Libraries Topoisomerase Inhibitors Xanthones Blotting, Western Tubulin Modulators Drug Resistance Topoisomerase II Inhibitors Neoplasms, Experimental Genes, MDR Cell Division Lung Neoplasms Neoplasm Transplantation Tumor Suppressor Protein p53 Base Sequence Adjuvants, Pharmaceutic HeLa Cells DNA Topoisomerases, Type I Coordination Complexes Flow Cytometry Cell Line Taxus Antineoplastic Agents, Alkylating Models, Biological Anticarcinogenic Agents Protein Binding Cell Cycle Checkpoints Clinical Trials, Phase I as Topic Particle Size

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