Loading...
  • iberiotoxin
  • Here, we investigated whether this venom component, called iberiotoxin, would be able to specifically block the FLS potassium channel and reduce the severity of the rheumatoid arthritis in rat models of the disease. (medindia.net)
  • We think that this venom component, iberiotoxin, can become the basis for developing a new treatment for rheumatoid arthritis in the future. (medindia.net)
  • Cuba
  • The drug, Vidatox 30 CH, is a biotherapeutic, with scorpion venom as active ingredient, manufactured by Cuba-based firm Labiofam and was formally introduced on the Nigerian market yesterday, the Daily Trust reports. (radiohc.cu)
  • Diluted venom from blue scorpions from cuba, has been used to fight cancer for long time now by tens of thousands of patients. (blogspot.com)
  • species
  • About 2,000 species have been described around the world, which also implies that scorpions are extremely well-adapted arthropods that have managed to survive in different environmental conditions. (springer.com)
  • Transcriptomics, in particular, has been widely used to explore the transcriptional diversity of venom glands of several scorpion species. (springer.com)
  • From then on, for more than two decades, the construction of cDNA libraries has been the main source of contribution to the discovery of new protein precursor sequences in many other scorpion species. (springer.com)
  • Scorpions are not an exception, and by now, reports have emerged describing the whole transcriptome sequencing of two species using next-generation methods: the African scorpion Pandinus imperator (Roeding et al. (springer.com)
  • Buthus
  • One of the components in the venom of the scorpion called Buthus tamulus specifically blocks the potassium channel of FLS and not the channels in other cells such as those of the nervous system," said first author Dr. Mark Tanner, a graduate student in the Beeton lab during the development of this project. (medindia.net)
  • inspiration
  • In the same way that traditional medicine uses natural products such as plants and flowers to treat a range of diseases, the IRB Barcelona lab has sought inspiration from venoms with the objective of identifying peptide shuttles. (neurosciencenews.com)
  • doses
  • The different sub lethal doses of the venom (20, 40, 60, 80 and 100 micrograms/kg) were injected subcutaneously in 6 group of rats (Each group containing 10 mature male rats).The control group was injected with normal saline. (vin.com)
  • However in low doses, venom will not affect normal cells while it may affect cancer cells, since cancer cells are most sensitive to e.g. modulation of various channels much needed for the very fast cellular division. (blogspot.com)
  • substantially
  • Recently, high-throughput sequencing platforms have substantially improved our capacity to describe biological features of scorpions but, most importantly, have outlined new directions toward a more complete understanding of the evolution of these arthropods. (springer.com)
  • News
  • PetLife Pharmaceuticals, Inc. (PINKSHEETS: EVGI) (PINKSHEETS: EVGID) today reported that CNN News has published a story, dated August 12, titled, "Bee, Scorpion and Snake Venom May Hold Cancer Cure. (nanotech-now.com)
  • describe
  • Here, we describe a new scorpion venom-derived K+ channel toxin (named λ-MeuKTx-1) with an ICK fold through gene cloning, chemical synthesis, nuclear magnetic resonance spectroscopy, Ca2+ release measurements and electrophysiological recordings. (inserm.fr)
  • deadly
  • That's because inside that deadly venom, there's actually tons of useful components that are helping pioneer breakthrough medicines. (businessinsider.com)
  • Scientist
  • Commenting on the CNN article, Arthur G. Mikaelian, Ph.D., PetLife Founder and CEO, said, "It's exciting to read of yet another mainstream scientist conducting positive ongoing studies related to animal venom. (nanotech-now.com)
  • diversity
  • However, scorpions are interesting organisms not only because of their toxin diversity but also because they represent the most ancient terrestrial animals that fossil records have identified. (springer.com)
  • Imagine that you are studying any particular scorpion, and you need to find out what is known about the molecular diversity of the potassium channel blockers that are part of its venom. (phys.org)
  • fold
  • Furthermore, similarities in precursor organization, exon-intron structure, 3D-fold and function suggest that scorpion venom ICK-type K+ channel inhibitors and Ca2+ release channel activators share a common ancestor and their divergence occurs after speciation between buthidae and non-buthids. (inserm.fr)
  • research
  • Current research on scorpion venom is slow going, but there are a number of medical possibilities. (opposingviews.com)
  • More research will need to be done to determine the true addictive qualities of this substance, and how those change when the venom is altered for use. (opposingviews.com)
  • Laura Leticia ValdezVelazquez , Head of research, said that when the toxin, derived from scorpion venom, invades channels in the cells with this disease it produces cellular damage until killing them. (blogspot.com)
  • Although the research is at a primary stage, this indicates the use of venom from scorpions used against cancer. (blogspot.com)
  • mixture
  • The venom is usually fast-acting, and it is composed by a mixture of neurotoxines, enzyme inhibitors, etc. (diff.org)
  • structural
  • The structural and functional characterizations of the first scorpion venom ICK toxin with K+ channel-blocking activity sheds light on functionally divergent and convergent evolution of this conserved scaffold of ancient origin. (inserm.fr)
  • components
  • One of the hundreds of components in scorpion venom can reduce the severity of the disease in without inducing side effects associated with similar treatments. (medindia.net)