Scleroderma localized. Medical search. Frequent questions

Localized fibrosing disorders include several clinical and histopathological conditions that are similar to the skin involvement of systemic sclerosis , but the systemic features are absent. (medscape.com)
The term includes a variety of diseases, from localized scleroderma (LS) to systemic sclerosis. (hindawi.com)
Scleroderma is an aspect of systemic sclerosis , a systemic connective tissue disease that also involves subcutaneous tissue, muscles, and internal organs. (medscape.com)
In the prospective Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, a phase 3 comparison of autologous HSCT with 12 successive monthly intravenous pulses of cyclophosphamide in 156 patients with early diffuse cutaneous systemic sclerosis, HCST was associated with higher treatment-related mortality than in the first year after treatment. (medscape.com)
Systemic scleroderma is also called systemic sclerosis . (mountsinai.org)
Scleroderma is primarily a skin disease, but when it affects other systems in the body, doctors call it systemic scleroderma, or systemic sclerosis. (medicalnewstoday.com)
Yes, a person can have lupus and scleroderma, or systemic sclerosis, at the same time. (medicalnewstoday.com)
Effective treatment of IPF, systemic sclerosis and localized scleroderma, represents an unmet medical need. (globenewswire.com)
3 UVA1 is one of the most recent advances in phototherapy for localized scleroderma and systemic sclerosis, and has been used more extensively in Europe than North America or Asia. (skintherapyletter.com)
This disorder, which occurs most commonly in children and young adults, should not be confused with progressive systemic sclerosis or scleroderma (it literally means 'hard skin'), which is characterized by Raynaud phenomenon and systemic organ involvement (that's why we prefer the term morphea). (contemporarypediatrics.com)
Scleroderma, or progressive systemic sclerosis, is an autoimmune connective tissue disease that involves sclerotic changes of the skin and may involve internal organs. (logicalimages.com)
Systemic sclerosis sine scleroderma - Raynaud phenomenon and systemic involvement without skin sclerosis. (logicalimages.com)
The systemic sclerosis overlap syndrome is characterized by features of one of the scleroderma subsets with those of another autoimmune disease (eg, lupus erythematosus , dermatomyositis , Sjögren syndrome , and/or rheumatoid arthritis ). (logicalimages.com)
Scleroderma, also called systemic sclerosis, is an autoimmune disease that produces scars and patches of thick, rough, or scaly skin. (facty.com)

Frontal linear scleroderma (also known as en coup de sabre or morphea en coup de sabre) is a type of linear scleroderma characterized by a linear band of atrophy and a furrow in the skin that occurs in the frontal or frontoparietal scalp. (wikipedia.org)
Multiple lesions of en coup de sabre may coexist in a single patient, with one report suggesting that the lesions followed Blaschko's lines. (wikipedia.org)
In scleroderma en coup de sabre (LScs) the atrophic lesion in frontoparietal area is the disease hallmark. (hindawi.com)
Linear scleroderma en coup de sabre (LCsc) is a rare subset of LS. (hindawi.com)
Neurologic symptoms (e.g. seizures/epilepsy, headaches/migraines, stroke) and/or ophthalmology conditions such as uveitis may occur in LoS of the head or face (en coup de sabre subtype, progressive hemifacial atrophy) [ 3 ]. (biomedcentral.com)
Our patient has a rare subtype of linear morphea called 'en coup de sabre,' or 'stroke of the sword,' so-called because of the characteristic linear lesions that occur on the frontoparietal scalp and forehead. (contemporarypediatrics.com)
En coup de sabre has been associated with neurological complications, including facial palsy, facial hemiatrophy, and seizures. (contemporarypediatrics.com)
2. Holland KE, Steffes B, Nocton JJ, et al: Linear scleroderma en coup de sabre with associated neurologic abnormalities. (contemporarypediatrics.com)

Scleroderma is more likely to cause serious complications if it affects your ability to breathe or process nutrition. (clevelandclinic.org)
What are possible complications of scleroderma in a child? (uhhospitals.org)
Complications of scleroderma vary depending on the type of the disease and how severe it is. (uhhospitals.org)
This form of scleroderma develops very slowly, causes few complications, and rarely spreads to other parts of the body. (healthstatus.com)
Other complications caused by systemic scleroderma are cancer, heart and kidney failure, pulmonary hypertension (high blood pressure in the lungs), and malabsorption (difficulty absorbing nutrients from food). (healthstatus.com)

Systemic scleroderma is a serious condition, while localized scleroderma carries a good prognosis and normal lifespan. (mountsinai.org)
Keep reading to learn about the similarities, differences, and relationship between lupus and scleroderma, including their symptoms, treatments, and prognosis for people with both conditions. (medicalnewstoday.com)

Morphea is a form of scleroderma that involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, with no internal organ involvement. (wikipedia.org)
Bullous scleroderma, a rare form of scleroderma, may have altered angiogenic and lymphangiogenic characteristics. (cdlib.org)
This form of scleroderma causes linear patches of tough, waxy skin and cut-like scars that crease the forehead, neck, and scalp. (facty.com)

MUSC's Division of Rheumatology & Immunology is one of the top ranked programs in the country by US News and World Report and an international leader in the field of scleroderma clinical care and research. (globenewswire.com)
Dr Li, from Hackensack University Medical Center, discusses findings from her study on clinical features in pediatric localized scleroderma and how a rheumatologist can approach current challenges in. (consultant360.com)
To expand upon current measures in pediatric scleroderma, researchers identified clinical features that defined disease activity, as well as specificity and their relative importance in physician activity. (consultant360.com)
Ongoing research & development programs and expansion of clinical experiments in the field of scleroderma diagnostics & therapeutics are projected to create lucrative opportunities for market growth. (growthmarketreports.com)

Widespread scleroderma can occur with other autoimmune diseases, including systemic lupus erythematosus and polymyositis . (medlineplus.gov)
Some drugs, such as rituximab (Rituxan), mycophenolate mofetil (CellCept), and imatinib mesylate (Gleevac), used to treat certain autoimmune diseases and cancers may play a role in treating scleroderma. (mountsinai.org)
Our rheumatologists work with doctors across UW Health to treat the effects of severe scleroderma and other autoimmune diseases. (uwhealth.org)
Scleroderma may occur in tangent with other autoimmune diseases such as systemic lupus erythematosus and polymyositis. (healthstatus.com)
Autoimmune diseases can be difficult to diagnose due to the variety of symptoms, and scleroderma is no exception. (mountain-ice.com)

Systemic scleroderma, or sclerosis -- May affect large areas of skin and organs such as the heart, lungs, or kidneys. (medlineplus.gov)
Localized scleroderma (LoS) is an autoimmune disorder characterised by inflammation and sclerosis of the skin and less commonly subcutaneous fat, in some cases only affecting the fasciae, muscles and bones. (biomedcentral.com)
Systemic scleroderma can lead to the hardening of internal organs (sclerosis). (uwhealth.org)
If you have diffuse scleroderma, you are at higher risk for developing sclerosis. (uwhealth.org)
Hyperkeratosis, epidermal atrophy, vacuolization of basal cells, dermal edema and sclerosis, perivascular lymphohistiocytic infiltrate, multifocal vesiculation and dermo-epidermal fends are seen in the scleroderma skin. (cdlib.org)
Another, more serious variant of the disease, is called Systemic scleroderma, or sclerosis, and can affect large areas of the skin as well as other organs such as the heart, lungs, and kidneys. (healthstatus.com)

Phototherapy using longer-wavelength ultraviolet A (UVA) light (ie, UVA1, 340-400 nm) has proved beneficial for cutaneous lesions in scleroderma. (medscape.com)
The young man's lesion is consistent with linear morphea, or localized cutaneous scleroderma. (contemporarypediatrics.com)
Keloidal scleroderma is a very rare cutaneous presentation of scleroderma, in which keloidal plaques develop in normal or sclerotic skin. (logicalimages.com)
This may be due to their likelihood of having diffuse, rather than limited, cutaneous systemic scleroderma. (logicalimages.com)

An estimated 300,000 Americans have scleroderma, although the difficulty of diagnosis makes this number hard to pin down. (mountain-ice.com)

Atrophoderma of Pasini and Pierini (also known as "Dyschromic and atrophic variation of scleroderma," "Morphea plana atrophica," "Sclérodermie atrophique d'emblée") is a disease characterized by large lesions with a sharp peripheral border dropping into a depression with no outpouching, which, on biopsy, elastin is normal, while collagen may be thickened. (wikipedia.org)
Localized scleroderma is a rare disease, characterized by sclerotic lesions. (hindawi.com)
Lobomycosis can be classified into localized or multicentric forms, depending on the extent of skin lesions. (cdc.gov)

The proposed study will investigate the esophageal involvement in the two forms of scleroderma (systemic and localized), compare the same and address any need of upper gastrointestinal evaluation in morphea (localized scleroderma) patients. (biomedcentral.com)
The present study was designed to investigate the esophageal involvement in the systemic (SSc) and localized (morphea) forms of scleroderma and to compare the same. (biomedcentral.com)
Children are more likely than adults to develop localized forms of scleroderma. (medscape.com)

Localized scleroderma affects the skin and underlying tissues. (medicalnewstoday.com)
An autoimmune disease that affects the skin, muscles, blood vessels, and internal organs is known as scleroderma. (growthmarketreports.com)

A localized or systemic chronic and progressive autoimmune disorder characterized by thickening of the skin and the connective tissues. (embl.de)

Localized scleroderma is called an autoimmune disease. (scleroderma.org)

In morphea scleroderma, patches of hard skin form and can last for years. (mountsinai.org)
If you have morphea scleroderma, you may have waxy patches of skin that vary in size and shape. (uwhealth.org)

In localized scleroderma, your immune system attacks the skin and tissue underneath as the 'foreign object. (scleroderma.org)
Scleroderma makes your body produce too much collagen, a protein that you need for healthy skin and tissue. (clevelandclinic.org)
Scleroderma can cause lots of symptoms and affect tissue throughout your body. (clevelandclinic.org)
Scleroderma makes patches of your skin and other tissue thicker than they should be. (clevelandclinic.org)
Scleroderma is a rare condition that makes your body produce tissue that's thicker than it should be. (clevelandclinic.org)
Scleroderma usually affects your skin, but can cause symptoms in any tissue throughout your body. (clevelandclinic.org)
Scleroderma is a disease that involves the buildup of fibrous tissue in the skin and elsewhere in the body. (medlineplus.gov)
An ECG may be done to find changes in the heart muscle tissue due to scleroderma. (uhhospitals.org)
Localized Scleroderma (LoS) is an autoimmune connective tissue disease that affects skin and less commonly subcutaneous tissues. (biomedcentral.com)
Scleroderma is an autoimmune disease - a condition caused when your immune system attacks your body's healthy tissue. (uwhealth.org)
Because scleroderma can affect your joints, bones, muscles and connective tissue, it is also considered a rheumatic condition. (uwhealth.org)
Systemic scleroderma affects your connective tissue and more parts of your body. (uwhealth.org)
Systemic scleroderma is more serious and affects connective tissue in many parts of your body, including internal organs. (adam.com)
Many early scleroderma symptoms are like those of other connective-tissue diseases, such as rheumatoid arthritis, lupus, and polymyositis. (adam.com)
Elizabeth Volkmann, MD, associate professor at UCLA, Director of the Scleroderma Program, and the codirector of UCLA's Connective Tissue Disease-Related Interstitial Lung Disease program, discusses treating. (consultant360.com)
Scleroderma is a connective tissue disease that is a type of autoimmune disorder causing changes in skin, muscle, blood vessels and internal organs. (healthstatus.com)
In the case of scleroderma, this rheumatic autoimmune disease tends to involve the thickening or tightening of the skin and the connective tissue under it, but many other symptoms may be present. (mountain-ice.com)
For example, tissue damage caused by excoriation can lead to localized infections and septicemia. (jcadonline.com)
However, a recent study has demonstrated that activated fibroblasts regulate tissue-localized transdifferentiation of regulatory T cells (Tregs) into T helper type 2 cell (Th2)-like cells through IL-33 in SSc lesional skin [ 2 ], suggesting that activated dermal fibroblasts amplify an aberrant immune response characteristic of SSc. (biomedcentral.com)

Morphea, also known as localized scleroderma, is characterized by predominant skin involvement, with occasional involvement of subjacent muscles and usually sparing the internal organs. (biomedcentral.com)
Internal involvement in localized scleroderma. (medscape.com)
Conversely, both fibronectin and collagen XVIII are increased in scleroderma skin, suggesting their involvement in the pathogenesis of bullous scleroderma. (cdlib.org)

Autoantibodies are frequently seen in localized scleroderma, particularly antinuclear antibodies and antibodies to single-stranded DNA and histones. (medscape.com)
The presence of anti-topoisomerase I, which is a specific type of antinuclear antibody, may indicate scleroderma. (medicalnewstoday.com)

CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasias) refers to a subset of patients with limited scleroderma. (logicalimages.com)

Experts estimate that all types of scleroderma affect around 250 out of every 1 million people in the U.S. Around 100,000 people in the U.S. have systemic scleroderma. (clevelandclinic.org)
Some types of scleroderma affect only the skin, while others affect the whole body. (medlineplus.gov)

Juvenile localized scleroderma (jLS) is a rare condition that can impair health-related quality of life, especially as it affects other body parts besides the skin. (carragroup.org)

Disease characteristics among pediatric patients with coexisting localized scleroderma and inflammatory arthritis may vary widely, according to study results published in the European Journal of Rheumatology . (rheumatologyadvisor.com)

The most common scleroderma symptom is having patches or streaks of thickened, waxy skin. (clevelandclinic.org)
Linear scleroderma begins as a streak or line of hardened, waxy skin. (uwhealth.org)
Raised, waxy skin accumulations known as morphea are a hallmark of localized scleroderma. (facty.com)

Normally, extra collagen is cleaned up when the repair is done, but in localized scleroderma, your skin keeps making more and more collagen. (scleroderma.org)
If you have scleroderma, your immune system triggers your body's cells to produce too much collagen (a protein). (clevelandclinic.org)
Scleroderma is a rare disease of unknown etiology, characterized by thickening and hardening of skin resulting from increased collagen production. (hindawi.com)
Endostatin, an anti-angiogenic C-terminal fragment of collagen XVIII, has been recently reported to play a role in scleroderma pathogenesis, but collagen XVIII immunohistochemistry in scleroderma skin has still not been performed. (cdlib.org)
The apparently normal skin from the patient with scleroderma shows histological signs of the disease, with thick collagen fibers and lymphatic ectasia. (cdlib.org)
sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease. (healthstatus.com)

Systemic scleroderma is characterized as either limited or diffuse. (uwhealth.org)

As we've said, diagnosing scleroderma can be difficult because some of the symptoms are shared with other autoimmune and rheumatic disorders. (mountain-ice.com)
Joint pain is associated with scleroderma and many other rheumatic diseases. (facty.com)

Scleroderma is a chronic condition, which means you'll need to manage your symptoms for a long time (maybe the rest of your life). (clevelandclinic.org)
Severe fatigue is associated with scleroderma and many other chronic illnesses. (facty.com)
Approximately 2.5 million individuals are affected with scleroderma globally, which makes it a chronic disease. (growthmarketreports.com)
There have been reports of using Dupixent to treat adult alopecia areata , chronic urticaria , localized scleroderma , and even keloids ," she told Medscape. (medscape.com)

Localized scleroderma usually affects only the skin on the hands and face. (mountsinai.org)
This type of scleroderma usually affects both sides of the body, meaning if you have problems with your left arm, you'll have problems with your right arm, too. (adam.com)

Low-dose UVA phototherapy for treatment of localized scleroderma. (medscape.com)

What are the symptoms of scleroderma in a child? (uhhospitals.org)

Morphea en plaque is more common in adults. (medscape.com)
Rarely, if this type of scleroderma affects children or young adults, it may interfere with growth and cause severe deformities in the arms and legs. (mountsinai.org)
This summary discusses scleroderma in adults. (logicalimages.com)
As per the internal reports from Britain and Japan, the occurrence of scleroderma in adults is approximately 35 in 1 million . (growthmarketreports.com)

There are neither sensitive nor specific laboratory tests for measuring disease activity in localized scleroderma (LS). (biomedcentral.com)
171 Linear scleroderma is a type of localised scleroderma which is an autoimmune disease characterized by a line of thickened skin which can affect the bones and muscles underneath it. (wikipedia.org)
Children and teenagers with active morphea (linear scleroderma, generalised morphea and mixed morphea: linear and circumscribed) may experience greater improvement of disease activity or damage with oral methotrexate plus prednisone than with placebo plus prednisone. (wikipedia.org)
The term scleroderma is derived from the Greek words skleros (hard or indurated) and derma (skin) and it is used to describe a disease characterized by progressive skin hardening and induration. (medscape.com)
Scleroderma is thought to be an autoimmune disease. (uhhospitals.org)
Scleroderma is an uncommon, complex, autoimmune disease. (mountsinai.org)
In children, localized scleroderma is three times more common than the systemic form of the disease. (mountsinai.org)
People with scleroderma may develop either a localized or a systemic (body-wide) form of the disease. (mountsinai.org)
Scleroderma is a disease that affects the whole body. (epnet.com)
Consider UW Health, home of a leading scleroderma treatment and research team, if you or a loved one are diagnosed with this autoimmune disease. (uwhealth.org)
Scleroderma is considered an autoimmune disease, meaning that the immune system mistakenly attacks the body's own tissues. (adam.com)
Histological and immunohistochemical aspects of skin biopsies are compared to normal skin from a patient without scleroderma and are correlated with the pathogenesis of the disease. (cdlib.org)
Variations of this disease may affect only the skin of the hands and face, this is referred to as localized scleroderma. (healthstatus.com)
Most reports point to a sclerodermalike disease rather than true systemic scleroderma. (logicalimages.com)
Due to this, research on the disease is limited and needs increased attention in order for doctors to better treat scleroderma. (mountain-ice.com)
About one-third of these patients have systemic scleroderma, the most serious form of the disease. (mountain-ice.com)
There are two types of the disease, localized and systemic scleroderma. (mountain-ice.com)
Living with scleroderma is difficult, as there is no drug that has been shown to stop or reverse the hardening and thickening of skin, the major symptom of the disease. (mountain-ice.com)
A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. (bvsalud.org)
Scleroderma is a long-term and rare disease that affects women more than men. (growthmarketreports.com)

No matter where you, your child, or a loved one are in your journey, or the type of scleroderma, the National Scleroderma Foundation can help you find your best path. (scleroderma.org)
Localized scleroderma (LS) is the most common type of scleroderma in children. (biomedcentral.com)
Which other symptoms you experience (and where they affect you) depends on which type of scleroderma you have. (clevelandclinic.org)
Scleroderma is a type of autoimmune disorder . (medlineplus.gov)
An antibody test may help show the type of scleroderma. (uhhospitals.org)
Symptoms differ from person to person and by type of scleroderma. (epnet.com)
Localized scleroderma is a milder type. (uwhealth.org)
Localized scleroderma is either morphea or linear in type. (uwhealth.org)
The other type… What is scleroderma? (familydoctor.org)
People with this type of scleroderma often have CREST syndrome. (adam.com)
Our aim is to report a rare case of bullous scleroderma, studying the presence of fibronectin and collagens type I, III and XVIII in sclerodermic skin. (cdlib.org)
Which type of systemic scleroderma is most likely to lead a patient to experience earlier organ damage? (consultant360.com)

Although the comorbid presentation of LS and inflammatory arthritis suggests an underlying systemic inflammatory component and perhaps even a shared immunopathology and a genetic component, additional studies are needed to clearly understand the relationship between localized scleroderma and inflammatory arthritis, and subsequently design the most appropriate treatment plan. (rheumatologyadvisor.com)
The growth of the market is attributed to the rising incidence of scleroderma cases and the increasing prevalence of genetic mutations along with the occurrence of extreme changes in the environment. (growthmarketreports.com)

Some people with scleroderma have a history of being around silica dust and polyvinyl chloride, but most do not. (medlineplus.gov)
Most people with scleroderma will develop only mild symptoms. (uwhealth.org)

Localized scleroderma: response to occlusive treatment with tacrolimus ointment. (medscape.com)
There is no specific treatment for scleroderma. (medlineplus.gov)
Many studies on scleroderma show some promise, but small sample sizes make it difficult to draw strong conclusions about treatment benefits. (mountsinai.org)
The drug was approved in Europe in 2007 for the treatment of skin ulcers related to scleroderma. (mountsinai.org)
Smaller units provide localized therapy, whereas whole-body treatment is best carried out using lie-down or standing UVA1 cabinets. (skintherapyletter.com)
The number of treatment sessions recommended for atopic dermatitis is usually 15 and for morphea or systemic scleroderma 20-40 treatments are given. (skintherapyletter.com)
3. Weibel L, Sampai MC, Visentin MT, et al: Evaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children. (contemporarypediatrics.com)
Linear scleroderma is typically diagnosed in childhood and has the potential to affect limb development, so responsive treatment is important. (facty.com)
Currently, no drug is available and approved for the treatment of scleroderma. (growthmarketreports.com)

Healthcare providers usually refer to limited scleroderma with the acronym CREST syndrome. (clevelandclinic.org)
Limited scleroderma, sometimes referred to as CREST syndrome, affects the face, hands and feet. (uwhealth.org)

Localized scleroderma rarely spreads and rarely affects your internal organs. (uwhealth.org)

Scleroderma can cause small blood vessels in the kidneys to become narrowed. (medlineplus.gov)
Symptoms range from mild to life-threatening, and in severe cases, scleroderma can damage the blood vessels and organs. (facty.com)
Despite the name, limited scleroderma may narrow the blood vessels of the lungs and lead to lung scarring, which can cause shortness of breath. (facty.com)

Doctors believe scleroderma is caused by the immune system mistakenly attacking the body's own tissues. (adam.com)

Digital ulcers are a serious complication in 50% of patients with scleroderma. (nih.gov)
Several studies have demonstrated a reduction of new skin ulcers and accelerated healing of nondigital ulcers for certain scleroderma patients after taking Bosentan. (mountsinai.org)

M. Meurer Four patients with systemic scleroderma and 1 patient with localized scleroderma were treated with ciclosporin (CS) given in daily doses between 2.2 and 5.6 mg/kg body weight for 3-26 months. (karger.com)
Available at: http://www.scleroderma.org/site/PageNavigator/patients_whatis.html#.Wy58BVVKhxA. (epnet.com)
Most scleroderma patients, including children, have just one or two patches of hard or rough skin. (facty.com)
Although most patients have mild to moderate scleroderma, severe forms can injure the lungs, kidneys, and heart. (facty.com)

Scleroderma can lead to scarring of the skin, joints, and internal organs. (uhhospitals.org)
MCP, PIP and DIP joints destruction in patient with Scleroderma. (healthstatus.com)
Typically only affecting the skin, localized scleroderma can spread to muscles, bones, and joints, but not to the internal organs. (mountain-ice.com)

X-rays may show changes in bone, soft tissues, and organs caused by scleroderma. (uhhospitals.org)
Scleroderma is a group of diseases that cause skin, and sometimes internal organs, to become hard and tight. (adam.com)
Persons only affected with localized scleroderma have a better outlook than persons suffering from systemic scleroderma as the condition is localized to only a small area of the skin on the face and hands and rarely if ever spreads to internal organs. (healthstatus.com)

Some people with early scleroderma don't have any symptoms. (clevelandclinic.org)

To diagnose scleroderma, your doctor will conduct a physical exam. (uwhealth.org)
It is not always easy to diagnose scleroderma. (adam.com)

Linear scleroderma and morphea can coexist in the same patient. (medscape.com)
Linear scleroderma tends to affect children and adolescents. (medscape.com)
Linear scleroderma. (medscape.com)
Linear scleroderma generally first appears in young children. (wikipedia.org)
patient data were identified from electronic medical records using diagnostic codes for morphea (ICD-9 701.0 and ICD-10 L94.0) and linear scleroderma (ICD-9 701.0 and ICD-10 L94.1). (rheumatologyadvisor.com)
There are two main forms of localized scleroderma: morphea and linear scleroderma. (mountsinai.org)
Linear scleroderma may also involve muscle or bone. (mountsinai.org)
linear scleroderma on the face or forehead. (mountain-ice.com)

Scleroderma symptoms can be intermittent or progressive depending on the form. (facty.com)

Characteristics of coexisting localized scleroderma and inflammatory arthritis [published online December 3, 2019]. (rheumatologyadvisor.com)

It is thought that the inflammation that accompanies the development of scleroderma initiates a keloidal response in those who are predisposed to keloid formation. (logicalimages.com)

Anatomy9

Diseases30

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Phenomena and Processes2

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Geographicals1

Systemic sclerosis14

Coup de sabre8

Complications5

Prognosis2

Form of scleroderma3

Clinical4

Autoimmune diseases5

Sclerosis6

Cutaneous4

Diagnosis1

Lesions3

Forms of scleroderma3

Affects the skin2

Connective tissues1

Called an autoimmune disease1

Morphea scleroderma2

Tissue19

Involvement3

Antinuclear2

Subset1

Types of scleroderma affect2

Juvenile1

Rheumatology1

Waxy skin3

Collagen6

Diffuse1

Rheumatic2

Chronic4

Usually affects2

Phototherapy1

Symptoms of scleroderma1

Adults4

Disease20

Type12

Genetic2

People with scleroderma2

Treatment9

CREST2

Rarely spreads1

Blood vessels3

Body's1

Ulcers2

Patients4

Joints3

Organs3

Early scleroderma1

Diagnose scleroderma2

Linear8

Progressive1

Inflammatory1

Inflammation1