Enzymatic degradation of collagen fibrils and invasion of inflammatory cells, including T cells and macrophages, appear to play an important role. (medscape.com)
The lattice arrangements of the collagen fibrils in the stroma. (wikidoc.org)
The extracellular matrix is uniform, the collagen fibrils are disposed parallelly with the same size and equally spaced, and the keratinocytes are transparent. (eyewiki.org)
[8] [9] The intra and extracellular accumulation of GAG lead to keratinocyte degeneration and disorganization of the collagen fibrils. (eyewiki.org)
Histologically, the tractional membranes may include components such as RPE cells, astrocytes, fibrocytes and collagen fibrils. (adrianbruce.au)
Sclera3
The sclera is perforated by many nerves and vessels passing through the posterior scleral foramen, the hole that is formed by the optic nerve. (wikipedia.org)
Sometimes, very small gray-blue spots can appear on the sclera, a harmless condition called scleral melanocytosis. (wikipedia.org)
Inflammation of the sclera can progress to ischemia and necrosis, eventually leading to scleral thinning and perforation of the globe. (medscape.com)
Lenses2
She is a pioneer of modern lens designs, and a specialist in contact lenses for irregular corneas, scleral lenses, myopia control, and orthokeratology. (contactlensupdate.com)
To correct your vision, we offer the most modern specialty contact lenses, including customized soft lenses, scan or impression based scleral lenses, with further visual clarity from individualized higher order aberration correction. (vision-institute.com)
Cornea2
Moreover, the cornea bears more mucopolysaccharide (a carbohydrate that has among its repeating units a nitrogenous sugar, hexosamine) to embed the fibrils. (wikipedia.org)
The nerves enter the cornea via three levels, scleral, episcleral and conjunctival . (wikidoc.org)
Optic2
7. Eilaghi A., Flanagan J.G., Simmons C.A., Ethier C.R. Effects of scleral stiffness properties on optic nerve head biomechanics. (glaucomajournal.ru)
Other treatment options include laser photocoagulation, cryotherapy, pneumatic retinopexy and scleral buckle. (adrianbruce.au)
Collagen9
Pathogenic mechanisms in scleritis are poorly understood, but enzymatic degradation of collagen fibrils by resident cells and infiltrating leukocytes seems to be a key feature. (medscape.com)
Enzymatic degradation of collagen fibrils and invasion of inflammatory cells, including T cells and macrophages, appear to play an important role. (medscape.com)
Next, we explored the diffusion of FITC-Dextran molecules using SHG&TPEF imaging, and concluded that the molecules tended to aggregate in the gaps between collagen fibrils, which suggested that the interfibrillar substances might play an important role in the trans-scleral penetration of molecules. (edu.hk)
Corneal crosslinking (CXL) is a technique to prevent progression of keratoconus that utilizes Vitamin B (Riboflavin) drops placed onto the cornea and then exposing the cornea to ultraviolet (UV) light to stiffen the cornea by crosslinking the collagen fibrils responsible for corneal stability. (doughertylaservision.com)
1. Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. (nih.gov)
3. Collagen fibril assembly during postnatal development and dysfunctional regulation in the lumican-deficient murine cornea. (nih.gov)
7. Altered collagen fibril formation in the sclera of lumican-deficient mice. (nih.gov)
11. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. (nih.gov)
The patient's biopsy from lesional skin revealed elastin and collagen fibril abnormalities, but biopsies from the clinically inconspicuous daughters showed only ultrastructural alterations of collagen fibrils. (lookfordiagnosis.com)
Posterior2
The sclera is perforated by many nerves and vessels passing through the posterior scleral foramen, the hole that is formed by the optic nerve. (wikipedia.org)
Ultrasound-mediated trans-scleral drug delivery offers a novel alternative for treating posterior eye diseases including age-related macular degeneration. (edu.hk)
Corneal1
The anterior or corneal segment, in consequence of its shorter radius, projects forwards, in front of the scleral portion, the union of the two parts being indicated, externally, by a slight groove, the sulcus scleræ. (co.ma)
Ocular1
15. Ocular and scleral alterations in gene-targeted lumican-fibromodulin double-null mice. (nih.gov)
Vessels2
interestingly, although the disease typically presents with engorgement of scleral vessels, vasculitis is not universally present at the microscopic level. (medscape.com)
In a healthy eye the scleral vessels are not prominent, but in patients with scleritis this vasculature is engorged. (medscape.com)
Composition1
Age-related, ethnic, and genetic differences in scleral composition may also contribute to glaucoma susceptibility. (molvis.org)
Cells2
In addition, RPE cells also may be dispersed into the vitreous cavity by excessive cryotherapy, cryotherapy on bare RPE, and scleral indentation following cryotherapy. (medscape.com)
Then HTM cells between Descement's membrane and the scleral spur were dissected using fine forceps and placed in a 35 mm 2 culture dish where cells were adhered to the plastic. (molvis.org)