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  • Embryonic Cell
  • Shoukhrat Mitalipov, director of the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University, developed the method that Chung's group built upon. (cmda.org)
  • We know that fertility declines as women get older," said Shoukhrat Mitalipov, Ph.D., co- senior author and director of the OHSU Center for Embryonic Cell and Gene Therapy. (eurekalert.org)
  • Normally, polar bodies disintegrate and disappear during egg development," said co-first author Hong Ma, M.D., Ph.D., with OHSU's Center for Embryonic Cell and Gene Therapy. (eurekalert.org)
  • Paul Knoepfler
  • Paul Knoepfler, an associate professor at the University of California at Davis who studies stem cells, called the new research "exciting, important and technically convincing. (cmda.org)
  • Over at UC Davis , stem cell researcher Paul Knoepfler , writing on his blog, called it a "milestone," but noted that while the potential is high, the risk is very high as well. (blogspot.com)
  • Robert Lanza of Advanced Cell Techn
  • Dr. Robert Lanza of Advanced Cell Technology of Worcester, Mass., one of the participants in the study, said it was the first to study the health of cloned animals well into adulthood, and was the best evidence yet showing that cloned animals can produce healthy and functional cells. (semissourian.com)
  • Our intent is to use this technology to generate stem cells to treat serious and life-threatening diseases, not to create a child," says Robert Lanza of Advanced Cell Technology (ACT) in an article in "Scientific American" (January 2002). (thenakedscientists.com)
  • Mitalipov
  • Mitalipov previously developed a mitochondrial replacement therapy involving the implantation of patient's egg nucleus - or spindle - into a healthy donated egg stripped of its original nucleus. (eurekalert.org)
  • mother's
  • The so-called three-parent IVF technique that was trialled in this research looked at how to prevent these "mitochondrial diseases" by replacing the mother's mitochondria with healthy mitochondria from a donor. (www.nhs.uk)
  • It involves transferring the nucleus of a mother's egg with faulty mitochondria into a donor cell with healthy mitochondria and other cellular components. (www.nhs.uk)
  • Roslin Institute
  • Before the experiment at the Roslin Institute, it was thought that once cells differentiated, they could not be used to generate an entire organism. (dnalc.org)
  • The scientists at the Roslin Institute solved this problem by growing sheep udder cells under starvation conditions. (dnalc.org)
  • sheep
  • For instance, in a sheep, udder cells could generate other udder cells, but not an entire sheep. (dnalc.org)
  • An egg cell was taken from another sheep. (dnalc.org)
  • These fused egg cells were then inserted into several different sheep. (dnalc.org)
  • This egg cell developed within a test tube until it was implanted into the uterus of the surrogate mother sheep. (study.com)
  • Once implanted, it continued to develop into an exact genetic replica of the donor sheep, also known as a clone. (study.com)
  • genes
  • With a series of microarray chips, Brambrink measured which genes were active and which were silent in both kinds of cells. (eurekalert.org)
  • such as skin cells -- and egg cells, which have the unique capacity to "reprogram" the genes in body cells and make them behave as though they were embryo cells. (sfgate.com)
  • In most cases, isolated genes or cells are duplicated for scientific study, and no new animal results. (aaenvironment.com)
  • Fertility
  • Women who donate some of their eggs to stem cell research will receive half-price discounted IVF treatment - a 1,500 stipend reducing the costs of one cycle of IVF treatment from 3,000 - at the Newcastle Fertility Centre. (ivf.net)
  • Ironically, there are stricter standards governing egg donors in a human research project than in a fertility clinic. (boston.com)
  • Until now, polar bodies had never been shown to be potentially useful for generating functional human eggs for fertility treatments. (eurekalert.org)
  • vitro fertilization
  • Egg donors are likely to undergo the same treatment as women do for in vitro fertilization. (boston.com)
  • This is potentially a way to double the number of eggs we're able to get from one session of in vitro fertilization. (eurekalert.org)
  • We hope that by doing this, we can double the number of patient eggs available for in vitro fertilization. (eurekalert.org)
  • Success rates for in vitro fertilization procedures, in which egg and sperm cells are combined in a lab dish, and other variations of assisted reproductive technology are at an all-time high. (infertile.com)
  • In vitro fertilization is an assisted reproduction technique and a type of technology used in stem cell research in which fertilization is accomplished outside the body. (aaenvironment.com)
  • fertilization
  • Analyzing the complete gene-expression profiles of both cloned and fertilization-derived stem cells in mice, scientists at Whitehead Institute for Biomedical Research now have concluded that the two are, in fact, indistinguishable. (eurekalert.org)
  • Tobias Brambrink, a postdoctoral researcher in the Jaenisch lab, tried a different approach, comparing gene expression in cloned and fertilization-derived stem cells. (eurekalert.org)
  • To ensure the accuracy of his results, he compared five lines of cloned stem cells with five fertilization-derived stem cell lines. (eurekalert.org)
  • involves
  • However, some scientists argue that this technique is too imperfect a science at this point - the success rate is significantly less than 0.5 per cent and so involves using a high, inefficient number of eggs. (ivf.net)
  • While the research published Thursday involves cells that are technically an early stage embryo, the intention is not to try to grow them into a fully formed human. (cmda.org)
  • He emphasized that the work involves eggs that have not been fertilized. (cmda.org)
  • Some doctors currently use a screening method called preimplantation genetic diagnosis, or PGD , which involves removing a single cell from an embryo and testing it for genetic defects. (infertile.com)
  • researcher
  • We have succeeded in the first and most important step of this process, which is to show we can make these very early human stem cells in a dish," said lead researcher Dr. Azim Surani. (medicaldaily.com)
  • I think this is an extremely important-and solid-paper," says stem cell researcher Robert Lanza, vice president of research and scientific development at Applied Cell Technology, a regenerative medicine company headquartered in Alameda, Calif., who did not take part in the study. (scientificamerican.com)
  • Prosecutors blamed the scandal, one of the most notorious cases of science fraud in recent years, on a combination of elements: a junior scientist who fabricated lab tests to please his boss, and Hwang himself, a charismatic head researcher who was blind to the scam but also ordered more fabrications to speed up the publication of his papers. (nytimes.com)
  • The researcher then tricks the egg into thinking it's been fertilized. (eurekalert.org)
  • Renowned stem cell expert, Swedish researcher Olle Lindvall, in an article at NewScientist.com (November 7, 2003), says he expects to be able to transform stem cells into the dopamine-producing neurons Parkinson's patients so badly need. (thenakedscientists.com)
  • ovaries
  • Four weeks later, the scientists removed them again, isolated immature egg cells from the ovaries and allowed them to mature in a dish. (time.com)
  • They cloned mice using cumulus cells, a cell type found in the ovaries. (dnalc.org)
  • One approach that may make egg freezing more successful is in vitro maturation, in which immature eggs are extracted from the ovaries and matured in the lab. (infertile.com)
  • The benefit of in vitro maturation in routine ART is that it prevents women from having to undergo hormone injections to stimulate their ovaries to release multiple mature eggs. (infertile.com)
  • destroyed for embryonic
  • This news story notes that it is 'technically an early stage embryo,' but goes on to minimize the humanity of this young being, created asexually in the lab, and instead point toward the theoretical possibilities if the embryo is instead used as raw materials, destroyed for embryonic stem cells that have in reality produced not a single therapy. (cmda.org)
  • immature
  • Immature eggs seem to survive freezing better than mature eggs, raising the possibility that doctors may one day harvest and freeze the immature eggs and then thaw and mature them when a woman is ready to start a family. (infertile.com)
  • moral
  • These arguments have been eagerly scooped up by the opponents of stem cell research, especially those folks who believe that an embryo in a dish is the moral equivalent of an MS patient in a wheelchair. (boston.com)
  • To many, the procedure skirts ethical and moral difficulties in creating new life from fertilizing an egg to harvest stem cells. (natcath.org)
  • Stem cell research is a complicated scientific and moral issue, and can impact the amount of technology used in stem cell research. (aaenvironment.com)
  • viable
  • The experimental research combined two types of stem cells and created a viable embryo - which the team say would provide an unlimited stock for medical research. (express.co.uk)
  • The problem with these approaches is that none of them has proved successful to date - and thus are not methods currently available for creating viable stem cell lines. (rutgers.edu)
  • Genetic preservation is the process that PERPETUATE uses to grow and then cryopreserve cells containing viable DNA from pets and horses. (perpetuate.net)
  • How long can cryopreserved cells be kept viable? (perpetuate.net)
  • PERPETUATE's cryopreserved cells can be kept viable for decades. (perpetuate.net)
  • Adipose and blood cells can be used to produce viable cell lines. (perpetuate.net)
  • mitochondria
  • In addition to potentially benefitting women of advanced maternal age, the technique may present another opportunity to help women known to have mutations in their mitochondria, the tiny powerhouses inside nearly every cell of the body. (eurekalert.org)
  • procedure known
  • The current experiment used seven young women as egg donors (a procedure known to risk their health), collecting a total of 126 eggs for experiments, but resulting in only two cell lines. (cmda.org)
  • diseases
  • It is intended to make the benefits of IVF more accessible to infertile women whilst addressing the shortage of high quality eggs for human stem cell research, thereby assisting scientists to progress in the global race to seek stem cell therapies for degenerative diseases such as Alzheimer's and Parkinson's. (ivf.net)
  • Techniques to transfer a nucleus from one cell to another are being perfected using monkeys because it may be easier to study deadly diseases such as AIDS using standardised animals (see p 4). (dhushara.com)
  • The promise of stem cell research to eventually lead to better treatments and cures for diseases afflicting millions of Americans today is powerful. (rutgers.edu)
  • PORTLAND, Ore, and LA JOLLA, Calif. - Families struggling with infertility or a genetic predisposition for debilitating mitochondrial diseases may someday benefit from a new breakthrough led by scientists at OHSU and the Salk Institute for Biological Studies. (eurekalert.org)
  • Scientists say the use of stem cells to grow new cells has the potential to treat or cure dozens of degenerative diseases, from heart disease to Parkinson's to kidney failure. (thenakedscientists.com)
  • The potential to discover genetic causes of diseases led many scientists to pursue genome-wide association studies, also referred to as GWAS. (issuu.com)
  • This technique can also be used to produce an embryo from which cells called embryonic stem ES cells could be extracted to use in research into potential therapies for a wide variety of diseases. (aaenvironment.com)
  • These stem cells would also allow scientists to better study the progression of specific diseases and provide more efficient means of testing new drugs. (americanprogress.org)
  • research
  • I agree that the left over eggs from IVF would be of more use if they were kept rather than destroyed, if they can be of help to research then what harm is there. (ivf.net)
  • Scientists at Whitehead Institute for Biomedical Research have success. (bio-medicine.org)
  • Scientists at Whitehead Institute for Biomedical Research have successfully demonstrated that a theoretical--and controversial--technique for generating embryonic stem cells is indeed possible, at least in mice. (bio-medicine.org)
  • Some suggest that this would quell the protests of critics who claim that embryonic stem cell research necessitates the destruction of human life. (bio-medicine.org)
  • Jaenisch--a firm supporter of all forms of human embryonic stem cell research--has shown that technical concerns about this approach can be overcome. (bio-medicine.org)
  • Jeffrey Janus, president and director of research for ISC, agrees that "Dr. Hwang's cells have characteristics found in parthenogenetic cells" but remains cautious, saying "it needs more study. (scientificamerican.com)
  • The prosecutors, however, failed to clarify what role South Korean government officials had played in the dramatic rise of Hwang as a national hero and as the government's first "supreme scientist," a title created for him that granted him millions of dollars in research funds. (nytimes.com)
  • He was also charged with using part of the funds to buy human eggs for his research in violation of the country's bioethics law. (nytimes.com)
  • Some scientists abused the people's high expectations and a lack of peer reviews and disregarded ethics of research to attain their own goals. (nytimes.com)
  • We need to contact our Senators and plead with them to pass the Stem Cell Research Enhancement Act without amendments - just like the one passed in the House. (rutgers.edu)
  • Legislation providing for so-called 'alternative methods' is no substitute for the bipartisan legislation that relaxes the federal limitations on stem cell research. (rutgers.edu)
  • The new work, led by Hui Zhen Sheng of Shanghai Second Medical University , appears in the latest issue of Cell Research, and was highlighted in a news report in the journal Nature. (sfgate.com)
  • Cell Research is a peer-reviewed -- if little known in the United States -- bimonthly scientific journal affiliated with the Shanghai Institute of Cell Biology and the Chinese Academy of Sciences . (sfgate.com)
  • A pair of advocates-they do legitimate research too, but their ardor is so intense, it's hard to call them scientists-believe that they will, within their lifetimes, make ours the first generation of humans to live forever. (flipboard.com)
  • A major breakthrough has just been achieved in stem cell research. (medicalnewstoday.com)
  • Before watching the video discuss with students what they know about stem cell research. (amnh.org)
  • Do you think stem cell research has the potential to eliminate disease? (amnh.org)
  • A UK-based research group previously transferred nuclei between human zygotes (zygotes are the cells formed when a sperm and an egg cell join) in 2010. (www.nhs.uk)
  • She and others raised their concerns in Massachusetts, where the Legislature just approved a bill promoting stem cell research. (boston.com)
  • Meanwhile, in California, Deborah Ortiz, a state senator who supported Proposition 71 for state-funded research, has asked for a three-year moratorium on multiple egg harvesting. (boston.com)
  • How do we compare them with women willing to donate eggs for research? (boston.com)
  • That's the finding of the Bedford Stem Cell Research Foundation, where director Ann Kiessling says, ''We are contacted regularly by people who have a serious illness in their family and would like to help. (boston.com)
  • The National Institutes of Health (NIH), interpreting the Dickey-Wicker Amendment, releases guidelines for research on ES cells. (researchamerica.org)
  • President George W. Bush prohibits the federal funding of any research using ES cell lines derived after August 9, 2001, but his policy does not affect research in the private sector or research conducted with state funding. (researchamerica.org)
  • Research on adult stem cells is not affected by this executive order. (researchamerica.org)
  • In the 110th Congress, the Senate passes their version of The Stem Cell Research Enhancement Act (S. 5) with strong bipartisan support, 63-34. (researchamerica.org)
  • President Barack Obama issues an executive order, titled "Removing Barriers to Responsible Scientific Research Involving Human Stem Cells. (researchamerica.org)
  • A group of plaintiffs led by adult stem cell scientists James Sherley, M.D., Ph.D., and Theresa Deisher, Ph.D., file a lawsuit against the National Institutes of Health (NIH) and the Department of Health and Human Services, arguing that federal funding of ES cell research is in violation of the Dickey-Wicker amendment. (researchamerica.org)
  • The NIH reasonably concluded, as expressed in the notice of proposed rulemaking, that the fundamental policy question of whether to provide federal funds for embryonic stem cell research wasn't a question for it to decide. (researchamerica.org)
  • Linvall's research has shown that the brain of a rat, after a stroke, actually produces new brain cells that travel to the damaged area. (thenakedscientists.com)
  • ACT is one of the very few private companies in the United States that kept working on stem cell research after the U.S. government dried up federal funds for the procedure. (thenakedscientists.com)
  • Some Catholic leaders, activists in the pro-life movement, and legislators oppose embryonic stem cell research, while others believe certain forms of the research present morally acceptable means of achieving long-sought medical gains. (natcath.org)
  • He maintained that the science behind his work was legitimate and said that his country was still a leader in the field of stem cell research. (netdoctor.co.uk)
  • Dr Hwang was the subject of scandal last month when he was forced to step down as the chairman of South Korea's World Stem Cell Hub after is emerged eggs used for research were from a female colleague, which is a breach of guidelines. (netdoctor.co.uk)
  • The basic human fear behind stem cell research is misanthropy, which is a hatred or distrust of mankind. (aaenvironment.com)
  • This can directly impact whether or not there will be advances made in the field of technology used in stem cell research. (aaenvironment.com)
  • In addition many other medical benefits are expected as technology used in stem cell research continues to advance. (aaenvironment.com)
  • This is a fairly new advance in technology used in stem cell research. (aaenvironment.com)
  • Research on stem cells and technology used in stem cell research is focusing on advancing knowledge about how an organism develops from a single cell and how healthy cells replace damaged cells in adult organisms. (aaenvironment.com)
  • These efforts to politically define complicated biological terms often results in ill-conceived laws that satisfy neither opponents nor supporters, confuse scientists attempting to pursue research in the state, and may even create legal problems for those attempting to conduct cooperative studies across state lines. (americanprogress.org)
  • Yet in reality, it's an attempt to politically redefine terms to help opponents of stem cell research. (americanprogress.org)
  • A reader of the New York Times warned of the danger of "front-loaded" arguments that can be detrimental to stem cell research. (blogspot.com)