Scientists disease resistance. Medical search. Frequent questions

However, with continued use of antibiotics, pathogens have developed antibiotic resistance that has rendered some antibiotics ineffective. (seattlechildrens.org)
Understanding how antibiotic resistance emerges is critical for the development of countermeasures to battle emerging antibiotic resistance. (seattlechildrens.org)
This so-called antibiotic-induced population heterogeneity is key to how organisms like Mtb develop antibiotic resistance. (seattlechildrens.org)
The gene encodes for an enzyme named EstT and is capable of 'turning off' or inactivating macrolides, a class of antibiotic drugs commonly used to treat disease in cattle and other livestock. (beefmagazine.com)
Antibiotic resistance, a subset of antimicrobial resistance, is one of the "biggest threats to global health , food security, and development today," the World Health Organization has said. (newsweek.com)
The team were partly inspired to explore this association off the back of a 2018 study published in the journal Nature , which showed the combination of rising local temperatures and population density in the U.S. was linked to an increase in antibiotic resistance. (newsweek.com)
Public health agencies worldwide have identified antibiotic resistance of disease-causing bacteria as one of humanity's most critical challenges. (sciencedaily.com)
Now, researchers reporting in ACS Infectious Diseases have uncovered the hidden antibiotic potential of a non-psychoactive cannabis compound called cannabigerol (CBG), which helped control methicillin-resistant Staphylococcus aureus (MRSA) infections in mice. (sciencedaily.com)
Much of her work focuses on antibiotic resistance and infectious diseases. (wunc.org)
The international team, co-led by computational chemist Gerhard Koenig at the University of Portsmouth, tackled the problem of antibiotic resistance by redesigning existing antibiotics to overcome bacterial resistance mechanisms. (acm.org)
Antibiotic resistance is one of the biggest threats to human health,' Koenig said. (acm.org)
It's only a matter of time until bacteria develop counterstrategies against our counterstrategies and become resistant to the new antibiotic, so we will have to keep on studying bacterial resistance mechanisms and develop new derivatives accordingly. (acm.org)
We will continue to work with the WHO, World Organization for Animal Health, and Food and Agriculture Organization to promote antibiotic stewardship to avoid the further emergence and spread of antibiotic resistance. (usda.gov)
The World Health Organization calls antibiotic resistance one of the three greatest threats to human health. (voanews.com)
Experts fear antibiotic resistance puts humans in danger of becoming nearly defenseless against some bacterial infections. (voanews.com)
We speak of the pre-antibiotic and antibiotic eras, but if we don't improve our response to the public health problem of antibiotic resistance, we may enter a post- antibiotic world in which we will have few or no clinical interventions for some infections,' he says. (voanews.com)
Urgent calls from health experts to reduce antibiotic use on intensive farms are largely resisted by the agribusiness food lobby, who downplay its role in the spread of antibiotic resistance in humans. (theecologist.org)
Although the figure is estimated to be lower in the UK, agriculture is believed to now account for the majority of antibiotic-resistance in food poisoning cases. (theecologist.org)
The continued overuse of antibiotics is being followed by a growing resistance as the bacteria evolve to withstand the effect and presence of the antibiotic. (theecologist.org)
But as they only limit the spread of bacteria rather than killing it, they are seen as a major factor in the spread of antibiotic-resistance. (theecologist.org)
Researchers have now discovered a novel resistance gene that allows bacteria to resist the impacts of an aminoglycoside antibiotic called plazomycin. (labroots.com)
Researchers had not known that this gene conferred resistance to an antibiotic until now. (labroots.com)
Early discovery of resistance genes can help us managing their spread, facilitate gene-based diagnostics and perhaps also guide industry to develop drugs that can circumvent the resistance,' said the senior study author Professor Joakim Larsson, director of the Centre for Antibiotic Resistance Research at University of Gothenburg, Sweden. (labroots.com)
Scientists fight antibiotic resistance by using synchrotron to study scab disease in potatoes. (lightsources.org)
In the ongoing war against antibiotic resistant bacteria, a change in battle tactics may prove effective for controlling a common disease of plants and potentially other toxins that affect humans and animals. (lightsources.org)
However, bacteria mutate quickly, as quickly as every 30 minutes, which leads to antibiotic resistance. (lightsources.org)
And the Antibiotic Resistance Lab Network performed more than 12,000 tests to contain the spread of resistant infections, just to name a few accomplishments. (cdc.gov)
Every day we are learning more about antibiotic resistance, which continues to be among the biggest health concerns in our country . (cdc.gov)
In 2017, CDC took several important steps to combat antibiotic resistance , including rolling out a containment strategy to slow the spread of drug-resistant diseases in healthcare facilities-starting with a single case-and supporting 25 innovators through a CDC pilot project to develop solutions to antibiotic resistance crises. (cdc.gov)
As we continued to work on lingering threats like antibiotic resistance and Zika, CDC also responded to new outbreaks in 2017, both at home and abroad. (cdc.gov)
Many of us in ID wring our hands and voice a lot of consternation at the rather slow pace of the development of new antibiotic agents, especially as resistance issues really seem to increase month by month and year by year. (medscape.com)
Emerging bacterial antimicrobial (antibiotic) resistance (AMR) is a global threat to human health. (who.int)
This chronic disfiguring and debilitating childhood infectious disease can be cured with a single oral dose of an inexpensive antibiotic. (who.int)

One very important application of this work is investigating how pathogens like Mycobacterium tuberculosis (Mtb) respond to antibiotics, as this helps inform how Mtb develops antimicrobial resistance or drug resistance. (seattlechildrens.org)
Researchers at the University of Saskatchewan have discovered how a previously overlooked gene is involved in antimicrobial resistance - a growing global issue that threatens the health and welfare of both humans and animals. (beefmagazine.com)
Antibiotics are becoming less effective due to the global spread of antimicrobial resistance. (beefmagazine.com)
Antimicrobial resistance genes (ARGs) - mobile genetic elements that can pass between microorganisms - help to accelerate resistance. (beefmagazine.com)
Ruzzini says that his team found the gene in a cluster with three other ARGs - the first clue that it could be involved in antimicrobial resistance. (beefmagazine.com)
Overusing antibiotics, in both humans and animals, is commonly blamed for the growing threat of what is known as antimicrobial resistance. (newsweek.com)
Such a climb is predicted to bring with it extreme weather events such as flooding and heatwaves, which could in turn affect access to food and-as the authors of the antimicrobial resistance study point out-public health. (newsweek.com)
Kaba commented: "Our present study could for the first time identify a potential association between climate change and antimicrobial resistance (AMR). (newsweek.com)
Dr. Tanner's research is primarily focused on environmental transmission of antimicrobial-resistant organisms and antimicrobial resistance genes in healthcare and community settings. (yale.edu)
She is also interested in waterborne pathogens such as Legionella and Salmonella Typhi, wastewater-based epidemiology, a One Health approach to antimicrobial resistance, bacterial cross resistance between disinfectants and antibiotics, and the role of biofilms in antimicrobial resistance gene exchange in waterborne pathogens. (yale.edu)
She has a passion for global health research and has worked on multiple projects focused on environmental antimicrobial resistance in India and Pakistan. (yale.edu)
We remain committed to addressing antimicrobial resistance in people and animals. (usda.gov)
The overuse comes at a cost as it contributes to an ever-increasing amount of antimicrobial resistance as bacteria evolve to withstand existing antibiotics. (theecologist.org)

The information encoded in the genomes of disease-causing bacteria, viruses, and fungi represent unique genetic fingerprints. (cdc.gov)
An illustration of the MRSA bacteria studied by the scientists. (newsweek.com)
Dissemination of carbapenemase-encoding plasmids by horizontal gene transfer in multidrug-resistant bacteria is the major driver of rising carbapenem-resistance, but the conjugative mechanics and evolution of clinically relevant plasmids are not yet clear. (cdc.gov)
Skin infections, lung infections, different bacteria causing these types of infections as they become more and more resistant, and then you get to more severe problem like tuberculosis in many parts of the world,' says Dr. Donald Poretz, an infectious disease specialist. (voanews.com)
Less than optimal dosing means the target bacteria survive and build resistance incrementally. (voanews.com)
This was despite the government saying at the time that the use of the drugs posed a risk to humans, with evidence of resistance spreading from animals through foodborne bacteria. (theecologist.org)
She reports, "The unique property of honey lies in its ability to fight infection on multiple levels, making it more difficult for bacteria to develop resistance. (naturalnews.com)
These slimy biofilms are bacteria communities which harbor diseases. (naturalnews.com)
Without this communication mode, the bacteria cannot release the toxins that increase their ability to cause disease. (naturalnews.com)
This allows bacteria to build up resistance over time, while the user also destroys the good bacteria in their gut. (naturalnews.com)
Although bacterial toxins cause serious, often deadly diseases, "bacteria aren't trying to be nasty," said Dr. Rod Merrill, Professor of Molecular and Cellular Biology at the University of Guelph. (lightsources.org)
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. (scienceboard.net)
We are closely tracking emerging infections like C. auris, continuing to study the effects of unusual diseases like Zika, and investigating and containing outbreaks of infections caused by a wide range of microbes such as Salmonella bacteria, monkeypox virus, and hemorrhagic fever viruses . (cdc.gov)
Pneumococcal conjugate vaccines are relatively new type of vaccine that has been shown to be highly effective at preventing disease and in stopping people from acquiring the bacteria in their noses and throats. (cdc.gov)
It has little cross-resistance to other bacteria and is predominantly used for staphylococcal infections. (medscape.com)

Faster testing could save lives and help doctors avoid broad-spectrum antibiotics, which can foster resistance. (the-scientist.com)
Like bacterial resistance to antibiotics, fungal resistance to medications is also growing worldwide, and the death toll will likely rise in the near future unless something is done now. (scitechdaily.com)
An example of this collaboration is a scientist from the School of Biomedical and Healthcare Sciences (part of PUPSMD) who specialises in the development and assessment of new antibiotics and antimicrobials. (plymouth.ac.uk)
Climate change could worsen the spread of microbes which are immune to drugs and substances we use to kill them, such as antibiotics, scientists have warned. (newsweek.com)
However, scientists haven't discovered a new class of antibiotics in more than 30 years. (sciencedaily.com)
Drug companies have cut back on production of antibiotics, and that contributes to the problem, scientists say. (voanews.com)
Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases (NIAID) says profits drive pharmaceutical companies to shy away from antibiotics. (voanews.com)
And it's getting worse, with fewer new antibiotics becoming available and resistance continuing to rise. (theecologist.org)

Researchers develop new vaccines and therapeutics to combat the spread of infectious diseases. (the-scientist.com)
Emerging AI technology is helping researchers determine how different cultivars respond to diseases like powdery mildew, with the aim of breeding pathogen-resistant varieties down the line. (thecounter.org)
Now, powerful imaging robots are helping researchers automate some of the most laborious parts of the grape breeding process, which in turn could significantly reduce the amount of time it takes to develop new, disease-resistant varieties. (thecounter.org)
Clarke led a team of researchers, scientists and engineers while at NMRI. (wikipedia.org)
In an accompanying eLife "Insight" piece commenting on the importance of the C. albicans drug resistance study, two researchers from the École Polytechnique Fédérale in Lausanne, Switzerland, wrote: "The work provides a global description of the genetic processes underlying drug resistance and adaptation in C. albicans . (sciencedaily.com)
Rutgers University-New Brunswick researchers have created four new varieties of sweet basil that are flavorful and resistant to disease, particularly to downy mildew, the plague of basil growers. (rutgers.edu)
The threat of Black Sigatoka, a leaf disease originally from Latin America, was also of concern to researchers. (abc.net.au)
Results, published in Nature , may help researchers develop new solutions for tumor resistance to targeted cancer therapies. (medicalxpress.com)
In other cases, the cause of drug resistance is less direct, though the researchers hypothesize that APOBEC3A causes extensive DNA damage that helps push tumor cells into a "persister" state that is more resistant to treatment. (medicalxpress.com)
Going forward, the researchers hope to gain further insight into the mechanisms by which APOBEC causes drug resistance, which may shed more light on how to develop a drug to inhibit APOBEC expression or activity. (medicalxpress.com)
Researchers have long studied naked mole rats for their long lifespans and exceptional resistance to age-related diseases. (yahoo.com)
Studies like the one described above help researchers understand disease progression and could eventually lead to advances in detection and treatment. (aacr.org)
In this study, which was reported in Microbiome , the researchers turned to the environment to look for resistance genes. (labroots.com)
The researchers identified that 19 lines that performed as well as the highly resistant check line, plus additional lines with low levels of resistance that could represent new minor forms of resistance against Rhizoctonia. (usda.gov)
This isn't the first time that researchers have made the connection between glucose, ketones and Alzheimer's Disease, but it is the first time it's been shown to happen on a cellular level. (thedoctorwillseeyounow.com)
Researchers can map out areas of the brain affected by Alzheimer's disease , for example, by assessing where patients' glucose uptake drops. (medscape.com)

Gene also present in pathogens that are responsible for causing bovine respiratory disease. (beefmagazine.com)
Ruzzini says scientists have previously identified the existence of this gene that's commonly found in many animal pathogens and their microbiomes, but its purpose remained a mystery. (beefmagazine.com)
This gene, even though we found it in an environmental organism, it is also present in pathogens that are responsible for causing bovine respiratory disease (BRD),' says Ruzzini. (beefmagazine.com)
More and more bacterial pathogens are developing resistance. (uni-bonn.de)
pathogens evolve or spread, and the spectrum of infec- tious diseases expands. (cdc.gov)
Periodontitis is a chronic infectious disease affecting the world adult population, characterized by the loss of gingival insertion and bone resorption as a result of the infect ion by periodontal pathogens, such as Porphyiromonas gingivalis (Pg), Prevotella intermedia (Pi), Tannerella forsythia (Tf) and Aggregatibacter (Actinobacillus) actinomycetemcomintans (Aa) 13 . (bvsalud.org)
3 Resistance to these pathogens is associated with poor response to treatment, prolonged hospitalization and excess mortality. (who.int)

The technology] is enabling us to do experiments to figure out which two or which three resistance genes will work best together. (thecounter.org)
Cadle-Davidson leads the collaborative's powdery mildew team, which seeks to discover which grape genes are responsible for expressing resistance to the fungus. (thecounter.org)
Most of the genes in these clusters are not well characterized and represent new candidates involved (in) drug resistance and adaptation to the host environment. (sciencedaily.com)
This new approach, called "functional phylogenomics," allows scientists to reconstruct the pattern of events that led to the vast number of plant species and could help identify genes used to improve seed quality for agriculture. (nyu.edu)
Chesi and colleagues investigated whether individual genes on chromosome 13 would impact disease initiation or progression. (aacr.org)
Furthermore, deleting one copy of miR15a/miR16-1 in mice with multiple myeloma significantly enhanced the aggressiveness of their disease and led to increased expression of genes that promote cellular proliferation. (aacr.org)
A number of entries with low levels of resistance could represent novel sources of minor RCRR resistance genes from crop wild relatives (20151019, 20131006, 20121054), but none of these were statistically different than the susceptible check. (usda.gov)
Using CRISPR-Cas9 gene editing, the scientists introduced genetic mutations by cutting DNA in certain locations of the genome and found some of the variants had major effects on the expression of nearby genes and could ultimately cause cancer. (scienceboard.net)
Other genes that are associated with blood fat (lipid) levels, inflammation, and the cardiovascular and immune systems contribute significantly to longevity because they reduce the risk of heart disease (the main cause of death in older people), stroke, and insulin resistance. (medlineplus.gov)

R. Grumet is also the lead PI for the USDA-SCRI CucCAP project: CucCAP: Leveraging applied genomics to increase disease resistance in cucurbit crops ( https://cuccap.org/ ). (msu.edu)
The CucCAP project: leveraging applied genomics to improve disease resistance in cucurbit crops. (msu.edu)
Today, pathogen genomics is part of almost every infectious disease program at CDC and has become central to the US public health system's efforts to identify, track, and stop infectious diseases. (cdc.gov)
Scientists at NYU's Center for Genomics and Systems Biology, the American Museum of Natural History, Cold Spring Harbor Laboratory, and the New York Botanical Garden have created the largest genome-based tree of life for seed plants to date. (nyu.edu)

Increasingly vector borne diseases are becoming common. (indiatimes.com)
This was just one of many vector-borne diseases CDC tackled in 2017. (cdc.gov)
In 1957, in the Islamic Republic of Iran, a child has blood taken to check for immunity against vector-borne diseases. (who.int)

A few people with partial resistance to Alzheimer's disease are causing a rethink of the condition's biological causes that could lead to new treatments. (newscientist.com)
The people with partial resistance to Alzheimer's are part of a community living in Colombia with high levels of a risky gene variant called PSEN1-280A , discovered in the 1980s. (newscientist.com)
It is suspected that in the early stages of Alzheimer's disease, tau build-up begins in the entorhinal cortex . (newscientist.com)
The findings could open the door to better treatments for many common diseases, including Alzheimer's and diabetes. (scitechdaily.com)
Chronic diseases - also known as non-communicable diseases - such as diabetes, heart failure, and Alzheimer's disease that catastrophically impact so many individuals, families, and the whole society are caused by problems of the mitochondria in the cells. (scitechdaily.com)
Most of us know at least one person affected by Alzheimer's Disease , an irreversible and progressive brain disorder that slowly destroys memories and thinking skills. (thedoctorwillseeyounow.com)
Alzheimer's Disease is increasingly being referred to as insulin resistance of the brain or Type 3 Diabetes. (thedoctorwillseeyounow.com)
As the study's senior author, Benjamin Bikman, a professor of physiology and developmental biology at Brigham Young, remarks: "Alzheimer's Disease is increasingly being referred to as insulin resistance of the brain or Type 3 Diabetes. (thedoctorwillseeyounow.com)
The scientists examined 240 brains post-mortem for RNA cellular sequences impacted by Alzheimer's. (thedoctorwillseeyounow.com)

June 2020 - Thurston Herricks shares insights from a recent publication in eLife with contributing authors from the Aitchison Lab at the Center for Global Infectious Disease Research (CGIDR). (seattlechildrens.org)
Windy Tanner is a clinical and environmental microbiologist with training and experience in infectious disease epidemiology. (yale.edu)
Transient OI is commonly experienced during dehydration or infectious disease. (medscape.com)

The progress to track and prevent C. auris is just one example of the important work experts from CDC's National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) tackled in 2017. (cdc.gov)
Dr. Prue currently serves as the associate director for behavioral science at CDC's National Center for Emerging and Zoonotic Infectious Diseases. (cdc.gov)
They worked with the National Center for Emerging and Zoonotic Infectious Diseases' (NCEZID) Dengue Branch in Puerto Rico, and the Puerto Rico Department of Health (PRDoH) to create nearly 400 unique maps to visualize historic dengue incidence, prevalence, and persistence for each municipality. (cdc.gov)

The current chair, India, is hosting a Meeting of Agricultural Chief Scientists in Varanasi, Uttar Pradesh, from 17 to 23 April 2023, entitled " Sustainable AgriFood Systems for Healthy People and Planet . (cimmyt.org)

Tata Trusts , the philanthropic arm of the Tata Group , is starting on a project to eradicate malaria from India completely by exploring the new gene-editing technology that modifies the DNA of Indian mosquitoes thereby halting the spread of the deadly disease. (indiatimes.com)
Malaria is a very tough disease to tackle. (indiatimes.com)
In disease prevention and control, sustained efforts are required against endemic diseases such as malaria, tuberculosis, poliomyelitis, rabies and HIV/AIDS, and against those diseases that periodically emerge as epidemics, including cholera, meningitis and influenza. (who.int)
Since 2000, expanded access to WHO-recommended malaria prevention tools and strategies has led to a significant reduction in the global burden of this disease: in 2021, there were 84 malaria-endemic countries, down from 108 in 2000. (who.int)
Malaria is a life-threatening disease, but it is both preventable and curable. (who.int)

They found that the fungus undergoes 240 genetic changes associated with drug resistance. (sciencedaily.com)
The disease that killed Gros Michel is caused by a fungus called Fusarium oxysporum fsp cubense, which lives in the soil and becomes virtually impossible to eradicate. (ktvu.com)
With a special ultraviolet light, scientists are able to detect yellow-orange areas on a little brown bat's wing that are currently under attack by the fungus that causes White Nose Syndrome. (nationalgeographic.com)
A little brown bat like those found in the railroad tunnel in Pennsylvania where scientists are applying compounds designed to trick the White Nose Syndrome fungus into thinking the environment is too dry to produce new spores. (nationalgeographic.com)
For example, the fungus Rhizoctonia solani causes severe disease in sugar beet fields resulting in above and below ground rotting. (usda.gov)
There are limited chemical controls for this fungus that last season long, so farmers rely heavily on genetic resistance. (usda.gov)

Over time, resistance to insulin can develop. (medscape.com)
Metabolic Syndrome (MS) is the denomination proposed by the World Health Organization (WHO) 42 , which designates a set of risk factors for cardiovascular diseases (CVDs), such as visceral obesity, dyslipidemia, high hypertension, glucose intolerance and insulin resistance 32 , which frequently are presented together. (bvsalud.org)
The definition by WHO demands the evaluation of the insulin resistance. (bvsalud.org)
On the other hand, the definition by NCEP-ATP III does not demand the measurement of the insulin resistance, making its use ease for epidemiological studies 5 . (bvsalud.org)
In the Japanese population, more than 20% of the population shows insulin resistance and in the adult population with diabetes mellitus type 2 the prevalence of metabolic syndrome ranges from 38 to 53%, depending on the gender and the criterion used 16 . (bvsalud.org)
The insulin resistance and the proinflammatory states play a key role in the MS pathogenesis 36 . (bvsalud.org)

Dr. Prue has a diverse portfolio of applied research projects supporting programs addressing food safety, vaccine safety, one health, Lyme disease, and viruses including rabies, Ebola, and Zika. (cdc.gov)
During CDC's emergency response to the Zika virus disease (Zika) outbreak, geospatial scientists used geographic information systems (GIS) to identify the most affected areas to target public health interventions. (cdc.gov)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
U.S. environmental employees were soon joined by similar "alternative" Twitter accounts originating from various science and health agencies, including the Food and Drug Administration, the National Institutes of Health, the Centers for Disease Control and Prevention and the National Weather Service. (yahoo.com)
Dr. Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention, calls on American lawmakers to address the problem. (voanews.com)
Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
US Centers for Disease Control and microbial signatures directly from clinical samples. (cdc.gov)

Current research in the Grumet lab focuses on fruit development and disease resistance in Cucumis (cucumber and melon) crops using a combination of molecular genetic, genomic and transgenic approaches. (msu.edu)
In Florida, which has a year-round growing season, basil crops had already been devastated by the disease. (rutgers.edu)
A report in 2008, conducted by over 400 international scientists and sponsored by the World Bank and United Nations, did not endorse GM crops as a solution to world hunger. (gardenorganic.org.uk)
All these crops are threatened by diseases because they are not constantly being conventionally bred for disease resistance,' Dale continued. (ktvu.com)

The new insights gained into mitochondrial quality control will boost efforts to develop new treatments for non-communicable diseases that have reached pandemic proportions and are estimated to cause 71% of all deaths. (scitechdaily.com)
Communicable diseases and related conditions remain an important challenge to public health, responsible for the death of an estimated 17 million people a year and for disabilities ranging from chronic anaemia, malnutrition and wasting to paralysis, mental retardation and elephantiasis. (who.int)
The burden of communicable diseases has been a key impediment to social and economic progress, imposing considerable suffering on people already living in adverse conditions. (who.int)
The epidemiology and demography of communicable diseases, once thought to be relatively stable, are instead evolving in tandem with other global trends. (who.int)
The above challenges underscore the need for all countries to monitor, prevent, and control the spread of communicable diseases and to care effectively for those who are infected. (who.int)
They also highlight the need for global leadership, global and national advocacy, and improved international cooperation in tackling communicable diseases. (who.int)
The Communicable diseases cluster is working to reduce the impact of communicable diseases worldwide by leading the global effort in surveillance, prevention, control and research. (who.int)
tracking epidemic and emerging diseases and anti-infective drug resistance, and locating communicable diseases geographically within countries, regionally and globally. (who.int)
C ensuring sustainable, cost-effective control of endemic communicable diseases at country level. (who.int)
C eliminating endemic communicable diseases as public health problems through intensified efforts to apply cost-effective strategies, during a fixed period of time, to decrease the incidence and prevalence of selected communicable diseases, or, in the case of eradication, to rid the world permanently of their presence. (who.int)
Most significant were public health advances that reduced premature death by decreasing the risk of infant mortality, increasing the chances of surviving childhood, and avoiding infection and communicable disease. (medlineplus.gov)
National Institute for Communicable Diseases, 4. (cdc.gov)
The National Institute for Communicable Diseases is notified of all suspected cases. (cdc.gov)

Whole-genome sequencing (WGS) is a laboratory procedure that determines the order of all or most of the nucleotides in the genome of these disease-causing microbes, enabling public health officials to better understand how microorganisms move through populations and change over time. (cdc.gov)
At the same time, rapidly developing resistance of microbes to anti- infective drugs is undermining treatment of bacterial, viral and parasitic diseases, weakening the weapons against them. (who.int)

It provides vital information for solving disease outbreaks and predicting drug resistance. (cdc.gov)
Several nations in Asia have had far larger outbreaks but have managed to bring the disease under control. (wunc.org)
Therefore continuous online monitoring about the interrelation between disease outbreaks and climate is of extreme importance. (who.int)
Identify climate change threats on communities to enhance control and prevention interventions and mitigate the spread of disease outbreaks. (who.int)
For the first time, scientists linked an outbreak of Seoul virus infections to pet rats in the United States, and AMD lab techniques proved critical in tracing this and other outbreaks. (cdc.gov)
CDC scientists traveled across the globe in 2017 to investigate a myriad of outbreaks , including an outbreak of anthrax infections in animals in Namibia that posed a threat to human health. (cdc.gov)

In the United States and elsewhere, infectious dis- health care reform, it is crucial that emerging infectious eases increasingly threaten public health and contrib- disease threats be addressed and that the basic tenets ute significantly to the escalating costs of health care. (cdc.gov)
Globicatella sanguinis osteomyelitis and Anthony M. Smith, Phuti Sekwadi, Linda K. Erasmus, bacteremia: review of an emerging human pathogen with an expanding spectrum of disease. (cdc.gov)

They report their findings in the paper "The evolution of drug resistance in clinical isolates of Candida albicans ," published by the open-access journal eLife . (sciencedaily.com)
The sensitivity of ODELAM allows us to detect different resistance states in individual clinical isolates. (seattlechildrens.org)

Scientists have found a compound that actually helps reverse resistance, at least in an infectious mouse model, with organisms inherently resistant to the drug alone. (medscape.com)

Here, we used genome sequencing of isolates sampled consecutively from patients that were clinically treated with fluconazole to systematically analyze the genetic dynamics that accompany the appearance of drug resistance during oral candidiasis [infection]. (sciencedaily.com)
All V. cholerae isolates are submitted to the Cen- tre for Enteric Diseases, which provides further labora- tory investigation, including phenotypic and genotypic characterization (Appendix 1, https://wwwnc.cdc. (cdc.gov)

Not just arbitrarily picking a resistance gene to cross into cultivated grapes, but to pick the one that's going to work for the longest time. (thecounter.org)

Due to the smaller class size and great teaching support, I was able to enjoy more meaningful interactions with supervisors during my final research project, which further boosted my research interest on metabolic diseases. (aston.ac.uk)
Type 2 diabetes is an example of a disease caused by metabolic dysfunction . (thedoctorwillseeyounow.com)
The addition of plant oils such as soybean oil (S) to a diet rich in saturated fatty acids is discussed as a possible route to prevent or diminish the development of metabolic disease. (bvsalud.org)
Although scientists still don't know why the ketogenic diet was effective for controlling seizures, they have documented the effectiveness of ketogenic diets for the treatment of diabetes and metabolic syndrome . (medscape.com)
Introduction: Metabolic syndrome (MS) is a complex pathology that combines several risk factors for cardiovascular disease. (bvsalud.org)
Objective: The aim of this study was to review the literature about the possible association between periodontal disease and metabolic syndrome and to identify the components of this syndrome that may contribute to this association. (bvsalud.org)

Delwart E. The Scientist, Nov 1, 2016. (cdc.gov)

First let me tell you a little about pneumococcal conjugate vaccines and pneumococcal disease. (cdc.gov)
When you add up all these infections, pneumococcal disease is a leading cause of infections and deaths around the world, especially in infants and the elderly. (cdc.gov)
Cynthia Whitney] The surveillance system in Israel was set up by working with all the hospitals in the country--26 of them--to get them to report every time a patient was treated there who had invasive pneumococcal disease. (cdc.gov)
The authors found that rates of pneumococcal disease did drop after the new vaccine program began. (cdc.gov)

We are especially interested in early stages of fruit growth and factors influencing fruit size, shape, cuticle and surface properties and resistance to infection by the oomycete pathogen, Phytophthora capsici . (msu.edu)
Changes in susceptibility to infectious diseases, increased opportunities for infection, and the rapid adaptation of microbial agents are among the factors contributing to this evolution. (who.int)
Periodontal disease (PD) is a chronic infection that produces a local and systemic inflammatory response. (bvsalud.org)

In the new research, scientists genetically modified mice to produce the naked mole rat version of the hyaluronan synthase 2 gene - responsible for making a protein that produces HMW-HA. (yahoo.com)
Dale doesn't believe the Cavendish banana will suffer the same fate as the Gros Michel banana, thanks to the work of scientists developing genetically-modified (GM) versions. (ktvu.com)

Advancements in microscopic imaging are helping grape breeders take a closer, more accurate look at how plants react to powdery mildew-a common fungal disease that attacks vineyards late in the growing season and can spoil entire harvests. (thecounter.org)
A fungal disease, called Panama disease Tropical Race 4 (TR4) , was first detected in 1990 in Taiwan and has spread to more than 20 banana-producing countries - including those in Central and South America, according to the Food and Agriculture Organization of the United Nations . (ktvu.com)

Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education. (the-scientist.com)
There is an urgent need for an integrated approach to disease surveillance, prevention and control. (who.int)
The manuscript we are discussing here talks about how surveillance for pneumococcal infections in Israel found that the new vaccine program was preventing a lot of disease, but they also detected an increase in one of the strains that the vaccine doesn't cover-- serotype 12F. (cdc.gov)
Rapid Diagnostic Tests for Neglected Infectious Diseases: Case Study Highlights Need for Customer Awareness and Postmarket Surveillance. (cdc.gov)
Background magnitude of the antimicrobial drug resistance crisis tious disease surveillance, more than 95 percent of is unknown because of the absence of systematic moni- these funds are limited to surveillance of diseases in toring. (cdc.gov)

Our research helps us understand the mechanisms that drive the process of drug resistance, which begin before the tumor becomes resistant. (medicalxpress.com)
To offer students an opportunity to explore disease mechanisms with lecturers selected for their research expertise. (aston.ac.uk)
The main hypothesis of the TAKEOFF study is "that if you target these fundamental mechanisms of aging, you would be able to impact many different diseases of aging across different organ systems. (medscape.com)

Commercial growers can now buy seeds of four new, disease-resistant varieties of sweet basil, thanks to Rutgers research. (rutgers.edu)
They surveyed existing varieties of sweet basil, looking for ones that were resistant to the disease, and struck out. (rutgers.edu)
Scientists also say this approach offers the potential for converting lymphoma cells that are resistant to treatment into more manageable forms of cancer. (innovations-report.com)
As a result, scientists are putting an increased focus on research to find more disease-resistant varieties that can match the eating quality of the popular Cavendish. (abc.net.au)
The second part of our work is about trying to actually understand this resistance, asking why some of the animals are resistant. (ed.ac.uk)
We help select the animals that are more resistant to diseases for breeding. (ed.ac.uk)
This results in each generation of fish being more and more resistant to important diseases. (ed.ac.uk)
The present study is crucial for understanding HEA behavior in oxidizing environments and provides insights into designing high-temperature-resistant materials, durable catalysts, and corrosion-resistance alloys for various applications,'Song concludes. (nanowerk.com)
Cavendish bananas dominated the global market in part because they were resistant to a disease that killed its predecessor - the Gros Michele variety. (ktvu.com)
One of the most lethal infections born out of bacterial resistance is Methicillin-resistant Staphylococcus aureus , commonly known as MRSA which kills 19,000 people in the United States every year. (voanews.com)
You can have worldwide resistance, some resistant to some drugs, some resistant to other drugs in different parts of the world,' he says. (voanews.com)
Similarly, 9 entries plus the resistant check FC705/1 showed statistically different levels of resistance compared to the susceptible check (20151020). (usda.gov)
Boger and colleagues [ 3 ] have tinkered with the drug using three different substitutions for the basic molecule that have overcome resistance issues with vancomycin -resistant enterococci (VRE). (medscape.com)

Some species have been absolutely decimated," says Winifred Frick , chief scientist at Bat Conservation International. (nationalgeographic.com)

Numerous other genetic mutations were found to be prevalent as drug resistance increased, though the functional impact of those changes is not known. (sciencedaily.com)

Society should definitely take advantage of these findings to promote regular exercise for health and disease prevention and develop effective exercise-mimetic drugs. (scitechdaily.com)
The recommendations erroneously conflate disease prevention with growth promotion in animals. (usda.gov)
USDA agrees that we need more data to assess progress on antimicrobial use and resistance, and we need to continue to develop alternative therapies for the treatment, control, and prevention of disease in animals. (usda.gov)
Dr Ann Olsson, a scientist in the Environment and Lifestyle Epidemiology Branch of the International Agency for Research on Cancer (IARC), received an award from the European Network for Smoking and Tobacco Prevention (ENSP) for her innovative proposal to prevent cancer among workers who have the highest risk of disease. (who.int)

Population growth and factors related to globalization, such as increased travel and trade, have the potential to spread and amplify infectious diseases and to create conditions for their re-emergence. (who.int)

APOBEC3A can directly cause mutations that are known to result in tumor resistance, such as mutations in the ALK gene. (medicalxpress.com)
Spontaneous natural mutations produce new traits, such as drought tolerance and disease resistance, which can help the plant to thrive. (cnn.com)
Shoba Sivasankar, head of Plant Breeding and Genetics for the joint FAO and IAEA Center of Nuclear Techniques in Food and Agriculture, explains that scientists are able to artificially induce plant mutations on Earth using gamma rays and X-rays. (cnn.com)

There is already significant local support for the development - a local man recently left £100,000 in his will to support research into brain tumours, while a local group with an interest in Huntington's disease is running a series of fundraising events and have already raised more than £10,000 for equipment vital to Huntington's research at Plymouth University. (plymouth.ac.uk)
Professor Drenth said the only solution to eradicating diseases like Black Sigatoka and Panama was for the industry to keep investing in research and development. (abc.net.au)
Increasing drug resistance, vector control and vaccine development are all challenging. (indiatimes.com)
Individuals who have an increased risk for multiple myeloma may be monitored for signs of the disease, but it is not currently possible to prevent the development of multiple myeloma. (aacr.org)
vulgaris) USDA-ARS breeding lines from the Fort Collins Sugar Beet Genetics Lab were screened for resistance to Rhizoctonia crown and root rot (RCRR) at the Colorado State University Agricultural Research, Development, and Education Center in Fort Collins, Colorado. (usda.gov)
The average daytime high was 30 degrees C the average nighttime low was 11.7 degrees C. During the first 14 days following inoculation, there were 10 consecutive days with temperatures exceeding 29.4 degrees C leading to rapid disease development with severe and uniform levels of RCRR in the nursery. (usda.gov)
BACKGROUND: Absolute dietary fat intake but even more so fatty acid pattern is discussed to be critical in the development of non-alcoholic fatty liver disease (NAFLD). (bvsalud.org)
The fat tissue itself is capable of producing several hormones and proteins involved in the development of diseases related to obesity 32,33 . (bvsalud.org)

Through screening the RIKEN natural product depository (NPDepo) and identifying a specific compound, NPD6433, that inhibits fatty acid synthase, they found this approach reduced fatalities in infected laboratory worms by about 50% and may offer a promising alternative to current treatments that are becoming less effective due to increasing drug resistance. (scitechdaily.com)
This is critical for detecting very small populations of resistance that can persist despite drug treatment. (seattlechildrens.org)
A new study by investigators from the Mass General Cancer Center, a member of the Mass General Brigham healthcare system, reveals how lung tumors may develop drug resistance over time, pointing to a protein, called APOBEC3A, that could be a promising target. (medicalxpress.com)
The authors found that the tumor cells surviving TKI treatment overexpress a type of APOBEC protein, APOBEC3A, which appears to cause drug resistance in two main ways. (medicalxpress.com)
Furthermore, it is not yet clear whether APOBEC drives acquired drug resistance in other cancer types or with use of other targeted therapies. (medicalxpress.com)
However, resistance to fusidic acid develops rather easily, especially with significant infections with high organism counts, which means that often it was combined with a drug such as rifampin . (medscape.com)

Scientists still struggle to detect and treat it. (the-scientist.com)
While overall the vaccine program benefits were great, the investigators did detect a small but significant increase in disease caused by nonvaccine serotypes, especially serotype 12F. (cdc.gov)

You'll discover more about the role biomedical scientists play in healthcare settings, and how their motivation, knowledge and innovative thinking is utilised. (aston.ac.uk)

Queensland scientists are striving to develop new varieties to keep Australia's most popular fruit on the menu for years to come. (abc.net.au)
People are given little of this and little of that to treat tuberculosis and tuberculosis germs develop resistance. (voanews.com)
Because of their healthy habits, these older adults are less likely to develop age-related chronic diseases, such as high blood pressure, heart disease, cancer, and diabetes, than their same-age peers. (medlineplus.gov)
The brothers and sisters of centenarians typically have long lives, and if they develop age-related diseases (such as high blood pressure, heart disease, cancer, or type 2 diabetes ), these diseases appear later than they do in the general population. (medlineplus.gov)

My work focuses on resistance to diseases. (ed.ac.uk)

In India, mosquito borne diseases are increasing. (indiatimes.com)
Genetic scientists are selected in India and being sent to the US for training," said Tata Trusts' Kumar.organisations who have got expertise. (indiatimes.com)
After identifying a resistance gene in samples of river sediment from India, the scientists compared the sequence of this gene to reported bacterial sequences. (labroots.com)

Scientists used one of the top supercomputers in Europe to keep pace with the impressive ability of diseases to evolve. (acm.org)

Consequently, the issue of cross-border transmission, coupled with population displacement driven by climate change, is a matter of concern that can exacerbate the spread of the disease. (who.int)
Occasionally, if a person catches a virus or their health is off in some other way, pneumococcus can grow and spread and cause disease. (cdc.gov)

Mice with the naked mole rat version of the gene were found to have better protection against both spontaneous tumours and chemically induced skin cancer, scientists said. (yahoo.com)

Intensive efforts are needed for diseases targeted for eradication and elimination, such as leprosy, lymphatic filariasis, dracunculiasis and Chagas disease. (who.int)

Anatomy9

Organisms67

Diseases8

Chemicals and Drugs42

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Psychiatry and Psychology1

Phenomena and Processes85

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture13

Humanities8

Information Science6

Named Groups3

Health Care6

Geographicals1

Antibiotic33

Antimicrobial Resistance13

Bacteria15

Antibiotics8

Researchers16

Pathogens7

Genes9

Genomics4

Vector borne diseases3

Alzheimer's9

Infectious disease3

Zoonotic Infectious Diseases3

20231

Malaria5

Fungus6

Insulin6

Zika2

Centers6

Crops4

Communicable13

Microbes2

Outbreaks6

Emerging2

Clinical isolates2

Organisms1

Isolates2

Picking a resistance gene1

Metabolic6

20161

Pneumococcal disease4

Infection3

Genetically modified2

Fungal disease2

Surveillance5

Mechanisms3

Resistant13

Chief scientist1

Genetic mutations1

Prevention4

Emergence1

Mutations3

Development8

Drug6

Detect2

Healthcare1

Develop4

Work focuses1

India3

Evolve1

Spread2

Tumours1

Eradication1