• replication
  • Besides checkpoint activation, Rad17 may also serve as a sensor of DNA replication progression, and may be involved in homologous recombination [ PMID: 15297881 ]. (ebi.ac.uk)
  • RAD17 shares strong similarity with DNA replication factor C (RFC) with which it forms a complex. (allelebiotech.com)
  • recruitment
  • Rad17 is phosphorylated by ATM at Thr622 resulting in a direct interaction of Rad17 with NBS1, facilitating recruitment of MRE11, RAD50 and ATM to the DNA double-strand breaks. (nih.gov)