Schizophrenia patients. Medical search. Frequent questions

Agitation refers to a spectrum of abnormal behaviors frequently seen in patients with psychiatric illnesses, including in individuals with schizophrenia or bipolar disorder. (ahdbonline.com)
As a result of these symptoms, individuals with schizophrenia can also have problems in their social functioning. (massgeneral.org)
The Johns Hopkins Schizophrenia Center strives to provide the finest possible clinical care for individuals with schizophrenia, schizoaffective disorders and related conditions as well as support for their families. (hopkinsmedicine.org)
To the best of our knowledge, no previous studies have addressed how individuals with schizophrenia who also met some definition of recovery manage the symptoms of their disease," said Amy Cohen, an associate research psychologist in the department of psychiatry and biobehavioral sciences at the Geffen School and the study's first author. (uclahealth.org)
There is a widespread misunderstanding that individuals with schizophrenia are violent and dangerous, often homeless, and beyond help,'' Cohen said. (uclahealth.org)
The brains of individuals with schizophrenia were less reactive to social rewards. (uclahealth.org)
In this project, genes that are disrupted by rare, damaging mutations in individuals with schizophrenia will be evaluated using CRISPRi in iPSCs. (uw.edu)
the authors noted individuals with schizophrenia are more nicotine dependent than the general population, and they experience greater reinforcing effects of nicotine and worse withdrawal symptoms during abstinence than the general population. (medscape.com)

[ 2 ] Schizophrenia is more common in men, and the diagnosis is made at a younger age in males. (medscape.com)
Because of the variability of symptom expression, diagnostic requirements of chronicity, and lack of pathognomonic features, an ED diagnosis of schizophrenia should be made cautiously. (medscape.com)
As a diagnosis-by-exclusion, schizophrenia must be distinguished from the numerous psychiatric and organic disorders that also can lead to psychotic disturbances in thinking and behavior. (medscape.com)
The diagnosis is best made by a psychiatrist who has throughly evaluated the patient, including historical episodes and corroborating information from family and friends. (medscape.com)
The proposed case shows the treatment of a woman with a diagnosis of schizophrenia who began treatment in a mental health centre and was later referred to a case managed SMI programme. (elsevier.es)
The aim of the present study was to investigate if time since schizophrenia diagnosis, body mass index (BMI), sex, metabolic syndrome, alcohol use, smoking, alanine transaminase (ALT), and body fat percentage (as measured by bioelectrical impedance) were associated with HS, determined by computed tomography (CT), in a population of patients diagnosed with schizophrenia. (aau.dk)
The aim of the present study was to investigate if time since schizophrenia diagnosis, body mass index (BMI), sex, metabolic syndrome, alcohol use, smoking, alanine transaminase (ALT), and body fat percentage (as measured by bioelectrical impedance) were associated with HS, determined by computed tomography (CT), in a population of patients diagnosed with schizophrenia.METHODS: Moderate to severe HS (40 CT Hounsfield units as threshold) was determined utilizing non-contrast enhanced CT. (aau.dk)
A diagnosis of schizophrenia must come from an experienced doctor who evaluates the symptoms and rules out other physical problems that could be causing them-for example, drug and/or alcohol abuse, or a brain tumor. (massgeneral.org)
The best introduction to schizophrenia is to listen to what the person with a diagnosis of schizophrenia actually says - and that is the introduction we have tried to give here. (scienceinschool.org)
To investigate whether there is any variation in month of birth among patients from equatorial Singapore with a diagnosis of schizophrenia. (cambridge.org)
All 9655 patients discharged from Singapore's national psychiatric hospital with a diagnosis of schizophrenia were included (year of birth range 1930-1984). (cambridge.org)
Because of the variability of symptom expression, diagnostic requirements of chronicity, and lack of pathognomonic features, an ED diagnosis of schizophrenia should be provisional at best. (medscape.com)
While the primary diagnosis of schizophrenia rarely is made de novo in the ED, several historical features can be helpful in distinguishing the illness from the many medical and psychiatric conditions that can mimic it. (medscape.com)
80 patients having diagnosis of schizophrenia according to ICD-10 are assigned to treatment with olanzapine (N=20), risperidone (N=20) and haloperidol (N=40). (who.int)
A recent study presented at the American Association for Geriatric Psychiatry Conference 2022 ( AAGP 2022 ) analyzed healthcare records and data linkages from 82,858 US veterans aged 50 years and older with a diagnosis of schizophrenia and at least one inpatient or two outpatient encounters related to that diagnosis within the previous 2 years. (medscape.com)
Diagnosis Schizophrenia is characterized by psychosis (loss of contact with reality), hallucinations (false perceptions), delusions (false beliefs), disorganized speech and behavior, flattened affect. (msdmanuals.com)

Psychosis and schizophrenia are not equivalent, although they are commonly mistaken as such. (medscape.com)
Psychosis is a major feature of schizophrenia, as it is in several other psychiatric disorders. (medscape.com)
These results are in line with recently published studies, which showed an increased prevalence of psychosis among patients with metabolic syndrome-related illnesses including diabetes. (nih.gov)
APA recommends that patients with schizophrenia who are experiencing a first episode of psychosis be treated in a coordinated specialty care program. (guidelinecentral.com)
APA recommends that patients with schizophrenia be treated with cognitive-behavioral therapy for psychosis (CBTp). (guidelinecentral.com)
Schizophrenia is the most common kind of "psychosis"-a term meaning to be out of touch with reality. (massgeneral.org)
Hydrocephalus ( 7 ), increased ventricular size ( 8 ), and cognitive impairment ( 9 ) have also been noted in some persons with schizophrenia and other forms of psychosis. (cdc.gov)
The most striking features of schizophrenia are those of psychosis - meaning delusions or hallucinations. (scienceinschool.org)
Schizophrenia is one of several psychiatric disorders for which psychosis is a major feature. (medscape.com)

Multivariate analysis demonstrated a trend towards improved symptom scores among those randomised to music therapy, especially in general symptoms of schizophrenia. (cambridge.org)
If you think someone you know may have symptoms of schizophrenia, talk to him or her about your concerns. (mayoclinic.org)
While psychotic hallucinations and delusions, the so-called positive symptoms of schizophrenia, are the most immediately apparent signs of illness, it is the negative symptoms─loss of volition, flat affect, social isolation─along with the cognitive impairments in memory and attention that are ultimately the most debilitating consequences. (bbrfoundation.org)
Medication may improve the positive symptoms of schizophrenia, and social and vocational functioning. (wikipedia.org)
Patients in this category may be prescribed clozapine, a medication that may be more effective at reducing symptoms of schizophrenia, but treatment may come with a higher risk of several potentially lethal side effects including agranulocytosis and myocarditis. (wikipedia.org)

Patients with early-stage schizophrenia who receive a combination of medication and a psychosocial intervention appear less likely to discontinue treatment or relapse -- and may have improved insight, quality of life and social functioning -- than those taking medication alone, according to a report in the September issue of Archives of General Psychiatry , one of the JAMA/Archives journals. (sciencedaily.com)
We are encouraged by these survey results as they indicate positive signs for the critically important relationship between psychiatrists, their patients and caregivers," said Larry Alphs, M.D., Therapeutic Area Leader Psychiatry, Ortho-McNeil Janssen Scientific Affairs, L.L.C. Dr. Alphs also is a consulting psychiatrist. (disabled-world.com)
This study, published in The Lancet Psychiatry journal, involved 150 patients in Britain who had had schizophrenia for around 20 years and who had been experiencing persistent and distressing auditory hallucinations for more than a year. (asianage.com)
It is one of the most intractable and difficult to treat psychiatric illnesses, with prognosis becoming progressively poorer the longer a patient has the disease, according to the study's senior author, Sophia Vinogradov , MD, professor and interim associate chief of staff for mental Health at SFVAMC and interim vice chair of psychiatry at UCSF. (ucsf.edu)
Psychiatry researchers Akira Sawa (Director of The Johns Hopkins Schizophrenia Center)and Thomas Sedlak have found that glutamate in broccoli sprouts may improve chemical imbalances in people with schizophrenia. (hopkinsmedicine.org)
Using a home-based assessment, Cherrie Galletly, MD, PhD, Discipline of Psychiatry, the University of Adelaide, Australia, and colleagues found that rates of sleep apnea in schizophrenia patients were twice those seen in the general population. (medscape.com)

Our extensive research efforts are driven by that same passion to find the causes of schizophrenia and related disorders and to develop treatments to improve the lives of patients everywhere. (hopkinsmedicine.org)
How much do we know about the causes of schizophrenia? (scienceinschool.org)

abstract = "OBJECTIVE: With hepatic steatosis (HS) being an established risk factor for CVD in the general population, it may also be a predictor of CVD in patients with schizophrenia. (aau.dk)
ABSTRACT We studied quality of life in 211 patients with schizophrenia from 2 outpatient clinics in Irbid, Jordan and Riyadh, Saudi Arabia, using the self-reporting questionnaire SRQ-24 and the modi- fied version of the schizophrenia quality of life scale. (who.int)
SEE NAMCS PATIENT DATASET NAMES FOR DSN ABSTRACT General Information This material provides documentation for users of the Micro-Data tapes of the National Ambulatory Medical Care Survey (NAMCS) conducted by the National Center for Health Statistics. (cdc.gov)
From the abstract: 'What is the therapeutic efficacy of multigenic pharmacogenomics-guided treatment in patients with schizophrenia? (cdc.gov)

Schizophrenia is a severe, chronic psychotic disorder. (medscape.com)
In particular, integrating a comprehensive therapy with medication treatment in patients with early-stage schizophrenia before the disease becomes chronic and disabling could improve long-term outcomes. (sciencedaily.com)
According to a new survey sponsored by Janssen,® Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc, 80 percent of patients with schizophrenia, a chronic, severe and disabling brain disorder, say their psychiatrists do well or very well in treating them with courtesy and respect. (disabled-world.com)
About Schizophrenia - Schizophrenia is a chronic, severe and disabling brain disorder that affects about 1 percent of the U.S. adult population and approximately 24 million people globally. (disabled-world.com)
Schizophrenia is a chronic and severe mental disorder which has serious consequences for both the patient and caregivers. (frontiersin.org)
Background: Schizophrenia (SZ) is a chronic multi genetic and multifactorial neurodevelopment disorder. (bmmj.org)
Recent Foundation-funded research led by NARSAD Distinguished Investigator Grantee Aaron Beck, M.D. at the University of Pennsylvania, demonstrates that a targeted form of cognitive therapy can improve psychosocial and cognitive abilities in low-functioning patients with chronic schizophrenia . (bbrfoundation.org)
Schizophrenia is a chronic brain disorder that affects approximately 24 million people (0.32% or 1 in 300 people) worldwide. (medicalert.org)
Schizophrenia is a chronic psychotic disorder, either persistent or episodic, whose hallmark features may include delusions, hallucinations, disturbed thinking processes, flattening of affect, and abnormal behaviors. (medscape.com)

In an innovative pilot, researchers have shown that using a computer game can help patients relax the part of the brain responsible for verbal communication, thus reducing hallucinations. (zmescience.com)
In other words, the patients gained a long-term ability to control their brains and significantly reduce the impact of schizophrenic hallucinations. (zmescience.com)
What this means is that by using this technique, patients learnt to control brain activity in the area of the brain that responds to voices - an area we know is hyperactive in people whom experience auditory verbal hallucinations. (zmescience.com)
Schizophrenia may result in some combination of hallucinations, delusions, and extremely disordered thinking and behavior that impairs daily functioning, and can be disabling. (mayoclinic.org)
An abrupt onset of hallucinations and delusional, bizarre, or disorganized thinking in patients who previously functioned normally may result in a better intermediate and long-term outcome. (medscape.com)
These categories refer to symptoms that are typical of a schizophrenia spectrum or other psychotic disorder (eg, delusions, hallucinations, disorganized thinking and speech, catatonic behavior), that cause substantial social and occupational distress and impairment, but that do not meet the full criteria for any specific disorder. (msdmanuals.com)

Bipolar disorder (BP) and schizophrenia (SCZ) are major psychiatric disorders, but the molecular mechanisms underlying the complicated pathologies of these disorders remain unclear. (nih.gov)
Coping with Agitation Associated with Schizophrenia and Bipolar Disorder: How Can Healthcare Professionals Help Their Patients? (ahdbonline.com)
2 Therefore, prompt and effective management of agitation is critically important in the care of schizophrenia or bipolar disorder, and it requires the skills and expertise of several types of professionals. (ahdbonline.com)
The recent development and approval of a first-generation antipsychotic drug that uses an inhalation-activated aerosol as its delivery modality is an important therapeutic advance in the management of patients with agitation associated with schizophrenia or bipolar disorder. (ahdbonline.com)
Patients with agitation associated with schizophrenia or bipolar disorder may get assistance from healthcare professionals in community-based, hospital, and day-hospital settings. (ahdbonline.com)
Three risk variants (rs1538979, rs821577, and rs821633) in the Disrupted-in-Schizophrenia-1 (DISC1) gene have previously been associated with both schizophrenia and bipolar disorder in a recent collaborative analysis of European cohorts. (sinapse.ac.uk)
In this study we examined the effects of these risk variants on brain activation during functional magnetic resonance imaging (fMRI) of the Hayling Sentence Completion Task (HSCT) in healthy volunteers (n = 33), patients with schizophrenia (n = 20) and patients with bipolar disorder (n = 36). (sinapse.ac.uk)
These findings may provide a better understanding of the neural effects of DISC1 variants and on the pathophysiology of schizophrenia and bipolar disorder. (sinapse.ac.uk)
By comparison, 15% of patients of the same age who had bipolar disorder or psychotic depression slept as much, as did fewer than 1% of the general population of the same age. (medscape.com)
The prevalence was greater in patients with bipolar disorder and in those with psychotic depression. (medscape.com)

FRIDAY, Jan. 28, 2022 (HealthDay News) - Schizophrenia and bipolar I patients experience cognitive decline through adulthood, although the nature of this decline varies across disorders and cognitive functions, according to a study published online Jan. 22 in the Schizophrenia Bulletin . (physiciansweekly.com)
In the present study, to recapitulate the pathologies of these disorders in vitro , we established in vitro models by differentiating mature neurons from human induced pluripotent stem cells (hiPSCs) derived from BP and SCZ patient with contributive copy number variations, as follows: two BP patients with PCDH15 deletion and one SCZ patient with RELN deletion. (nih.gov)
Few studies have compared this burden among caregivers of patients with eating disorders and other mental illnesses. (biomedcentral.com)
The objective of this study was to compare caregiver consequences in eating disorders (ED) with caregiver consequences in depression and schizophrenia, assessed with the same instrument, the Involvement Evaluation Questionnaire (IEQ). (biomedcentral.com)
The burden of caregiving is higher among caregivers of patients with eating disorders patients than among caregivers of patients with depression or schizophrenia. (biomedcentral.com)
Other studies on the consequences of providing care for patients with affective disorders also suggest that the relatives of these patients experience considerable distress, sometimes strikingly similar to those in schizophrenia [ 17 - 19 ]. (biomedcentral.com)
Schizophrenia is one of the world's most misunderstood and socially stigmatized mental health disorders. (medicalert.org)
Schizophrenia is typically diagnosed by ruling out other mental health disorders first and confirming that symptoms are not due to medications, drugs, or a medical condition. (medicalert.org)
FLORENCE, Italy - A large proportion of schizophrenia patients suffer from a range of sleep disturbances - a finding that shines a light on an underexamined area in major psychiatric disorders. (medscape.com)
As part of the international Stanley Global Neuropsychiatric Genomics Initiative, the researchers launched the Finnish SUPER (Finnish Study on Genetic Mechanisms of Psychotic Disorders), which aims to recruit 10,000 patients who have major psychiatric disorders by the end of 2018. (medscape.com)
Emphasizing the fact that the results are "still very preliminary and our research into sleep is still in its infancy," she said that the role of sleep disturbances in patients with major psychiatric disorders is still not clear. (medscape.com)
Treatment with antipsychotics can cause metabolic side effects leading to medical disorders among the patients suffering from schizophrenia. (who.int)
These patients were more likely to suffer from substance abuse, depression, schizophrenia, and paralytic disorders compared to the reference cases. (cdc.gov)
Introduction to Schizophrenia and Related Disorders Schizophrenia and related psychotic disorders- brief psychotic disorder, delusional disorder, schizoaffective disorder, schizophreniform disorder, and schizotypal personality disorder-are characterized. (msdmanuals.com)

Methods: In this study, 52 paranoid patients, and 33 healthy persons were selected. (bmmj.org)
Aims: To study the effects on glucose and lipid metabolism with the use of atypical and typical antipsychotics in the treatment of schizophrenia Methods: The present study is a 12 weeks open label prospective study of antipsychotic drugs olanzapine, risperidone and haloperidol in patients with schizophrenia. (who.int)
Methods: For this retrospective study, patients injured as a result of contact with law enforcement personnel were identified using ICD-9 external cause of injury codes from medical record databases of patients treated in all hospitals and trauma units in Illinois between 2000 and 2009. (cdc.gov)

APA recommends that patients with treatment-resistant schizophrenia be treated with clozapine. (guidelinecentral.com)
APA recommends that patients with schizophrenia be treated with clozapine if the risk for suicide attempts or suicide remains substantial despite other treatments. (guidelinecentral.com)
The Clozapine Consultation Clinic at Johns Hopkins Hospital offers a one-time, second opinion evaluation for patients with schizophrenia who may benefit from clozapine. (hopkinsmedicine.org)
The researchers performed home sleep studies with polysomnography in 30 schizophrenia patients who were being treated with clozapine . (medscape.com)

We aimed to further the understanding of some of the underlying genetics of schizophrenia, using left superior temporal gyrus (STG) grey matter thickness reduction as an endophenoptype in a genome-wide association (GWA) study. (nih.gov)

and 151 caregivers of patients with schizophrenia. (biomedcentral.com)
The sample size of both pilot studies however was small (e.g., 30 caregivers of patients with schizophrenia and 32 of ED patients in the study of Graap et al. (biomedcentral.com)
24 caregivers of patients with schizophrenia randomly selected from a mental health service. (bvsalud.org)

The dendrite and synapse phenotypes of isogenic neurons were partially similar to those of patient-derived neurons. (nih.gov)
Cell lines will be evaluated for phenotypes relevant to schizophrenia. (uw.edu)
Three distinct phenotypes of offenders with schizophrenia have been identified: individuals with a childhood onset of conduct disorder who display antisocial and aggressive behaviour both before and after schizophrenia onset, individuals with no history of conduct problems who begin engaging in aggressive behaviour at the onset of illness, and individuals who engage in a severe physical assault after many years of illness. (researchgate.net)
Using MiXeR, the study showed that several genetic variants underlying schizophrenia also influence CVD phenotypes, particularly risk factors of smoking and BMI. (medscape.com)

Delusions occur in most people with schizophrenia. (mayoclinic.org)

Schizophrenia affects about 1 percent of the U.S. adult population and approximately 24 million people globally. (disabled-world.com)

The management of schizophrenia usually involves many aspects including psychological, pharmacological, social, educational, and employment-related interventions directed to recovery, and reducing the impact of schizophrenia on quality of life, social functioning, and longevity. (wikipedia.org)

Researchers have identified various risk factors for schizophrenia, including heredity, brain damage and environmental factors such as social stress, isolation and drug use. (disabled-world.com)
To this end, in a first-of-its-kind study, researchers from Okayama University, Japan, conducted a randomized trial to assess the benefits of interventions for early cancer screening in patients with schizophrenia. (ascopost.com)
In adapting CBT for these patients, the researchers designed an approach that highlighted patients' interests, assets, and strengths, and stimulated them to focus on achievable long-term goals, such as independent housing, employment or social relationships. (bbrfoundation.org)
Researchers believe that psychological triggers such as extremely stressful life events could cause schizophrenia to develop in people who are already at risk of developing the disorder. (medicalert.org)
A new study by researchers at the David Geffen School of Medicine at UCLA and colleagues at the University of Southern California describes some of the strategies people with schizophrenia have used to overcome the disorder and function successfully in their careers. (uclahealth.org)
The researchers conducted up to three interviews each with 10 men and 10 women with schizophrenia from the Los Angeles area. (uclahealth.org)
In imaging studies, UCLA researchers found that the brains of people with schizophrenia are less sensitive to social rewards, such as the positive feelings that can come from social interactions with people, than they are to so-called nonsocial rewards, such as money or objects. (uclahealth.org)
To study the brain's response to different stimuli, researchers recruited 27 people with clinically stable schizophrenia and 25 healthy individuals. (uclahealth.org)
The findings provide additional evidence of disrupted social rewards processing in people with schizophrenia, researchers say. (uclahealth.org)
Researchers obtained what they call an "unprecedently large" set of GWAS samples, including schizophrenia (53,386 patients and 77,258 controls) and various CVD risk factors. (medscape.com)
The emergence of human induced pluripotent stem cell (hiPSC) technology has allowed researchers to work with SZ patient-derived neuronal and glial cell types in vitro and to investigate the molecular basis of the disorder in a human neuronal context. (lu.se)
Researchers assessed 20 common psychiatric and medical conditions other than schizophrenia. (medscape.com)

Yet for the person with schizophrenia, they have the full force and impact of a normal experience. (mayoclinic.org)
A person with schizophrenia can have varying symptoms that might change over time. (massgeneral.org)

Both common and unique pathophysiological mechanisms may underlie cognitive deficits in schizophrenia and bipolar I across the adult lifespan," the authors write. (physiciansweekly.com)
These findings suggested the involvement of HPS4 in the working memory of healthy subjects and in the executive function deficits in schizophrenia. (qxmd.com)

After getting his symptoms under control, MacPhee went on to launch SZ Magazine, a quarterly magazine designed to bring hope and information to people living with schizophrenia. (disabled-world.com)
An experimental therapy for people with schizophrenia that brings them face to face with a computer avatar representing the tormenting voices in their heads has proved promising in early stage trials. (asianage.com)
Schizophrenia is a psychiatric disorder that affects around one in 100 people worldwide. (asianage.com)
Music therapy may provide a means of improving mental health among people with schizophrenia, but its effects in acute psychoses have not been explored. (cambridge.org)
Despite the development of community-based services which reduce the need for in-patient care, many people with severe mental illness continue to need periods of in-patient treatment. (cambridge.org)
People with schizophrenia who completed 80 hours of intensive, computerized cognitive training exercises were better able to perform complex tasks that required them to distinguish their internal thoughts from reality. (ucsf.edu)
Schizophrenia strikes about 1 percent of all Americans and about 51 million people worldwide. (ucsf.edu)
In the study, the brains of 31 patients with schizophrenia and 15 healthy people used for comparison were scanned using functional magnetic resonance imaging (fMRI) while they performed a reality-monitoring task. (ucsf.edu)
Results may help mental health clinics when considering ways to improve social and thinking skills in people with schizophrenia. (pcori.org)
The research team is working with 19 mental health clinics in New England to recruit 378 people with schizophrenia. (pcori.org)
The dissemination of this intervention into routine clinical practice may help bridge the gap between early detection of cancer and mortality across people with schizophrenia and the general population," Dr. Fujiwara noted. (ascopost.com)
Disturbances of self-face recognition in people with schizophrenia may reflect the underlying neurobiological and psychological factors of the disorder. (nel.edu)
Schizophrenia is a serious mental disorder in which people interpret reality abnormally. (mayoclinic.org)
People with schizophrenia require lifelong treatment. (mayoclinic.org)
People with schizophrenia often lack awareness that their difficulties stem from a mental disorder that requires medical attention. (mayoclinic.org)
These are called "positive symptoms": People with schizophrenia experience them, others don't. (massgeneral.org)
People with schizophrenia are sometimes also unengaged in certain things. (massgeneral.org)
This is why it is so important for people living with the condition to wear a MedicAlert medical IDs for schizophrenia. (medicalert.org)
MedicAlert's protection plans offer benefits that extend beyond the ID, providing safety and peace of mind for people living with schizophrenia, their families and caregivers. (medicalert.org)
People living with schizophrenia have an altered or distorted perception of reality. (medicalert.org)
Schizophrenia affects about 1 in 100 people and is recognised worldwide. (scienceinschool.org)
People who have schizophrenia may be worried that the disorder will prevent them from living independently, pursuing higher education or holding down a demanding job. (uclahealth.org)
Prior studies have shown that half to two-thirds of people with schizophrenia will significantly improve or fully recover, enabling them to live fulfilling and productive lives. (uclahealth.org)
Cohen said she hopes the findings provide encouragement for people battling the stigma of mental illness and that the study helps inform treatment for schizophrenia. (uclahealth.org)
Conversely, in people with schizophrenia, abnormalities in how the brain processes social rewards likely contribute to human interaction problems. (uclahealth.org)
One of the hallmarks of schizophrenia is the impairment of social function, which includes the ability to conduct everyday conversations and maintain relationships with other people. (uclahealth.org)
When comparing machines that gave dollar-bill payouts, levels of activity in the brain were similar in people with and without schizophrenia. (uclahealth.org)
However, when comparing machines that gave payouts of human smiling faces, the level of activity in the brain was much lower in people with schizophrenia than in healthy individuals. (uclahealth.org)
If the established winter excess in births of people who subsequently develop schizophrenia is an effect of 'seasonality', this would be testable by examining the pattern of births in an equatorial region with no formal seasons. (cambridge.org)
People with schizophrenia are at increased risk, as compared to the general population, to be convicted for violent crimes because they are more likely to engage in aggressive behaviour towards others. (researchgate.net)
Olanzapine is highly effective for treating psychotic symptoms in people with schizophrenia but can cause significant weight gain resulting in metabolic disease. (psychnews.org)
Schizophrenia is a disorder that can be debilitating for people who experience it, and it is more prevalent than many of us would presume. (psychiatry.org)
this is in line with evidence of low BMI being a risk factor for schizophrenia, although obesity is more common in people with schizophrenia. (medscape.com)
It also appears to reduce suicide in people with schizophrenia. (wikipedia.org)
Patients are increasingly the conventional type of management, viewed as people and not just cases. (who.int)

Go to Schizoaffective Disorder , Childhood-Onset Schizophrenia , and Schizophreniform Disorder for complete information on these topics. (medscape.com)
The team found that 30% of patients aged 18 to 40 years who had schizophrenia or schizoaffective disorder reported sleeping more than 10 hours a day. (medscape.com)

Neuronal oscillations reflect the activity of neuronal ensembles engaged in integrative cognition, and may serve as a functional measure for the cognitive impairment in schizophrenia. (harvard.edu)
Schizophrenia involves a range of problems with thinking (cognition), behavior and emotions. (mayoclinic.org)
The cognitive functions of patients and healthy subjects were evaluated with the Brief Assessment of Cognition in Schizophrenia, Japanese-language version, and the patients were assessed for their symptomatology with the Positive and Negative Symptom Scale (PANSS). (qxmd.com)
A second study, which was also presented at the meeting, suggests that 6 months of treatment not only improved sleep in this patient population but also resulted in improved cognition, weight loss, and reductions in systolic blood pressure. (medscape.com)

Patients: Cross-sectional study, we investigated 26 out-patients(12 males, age 31.3±1.3 years, BMI 28.2±1.0 kg/m2) with stable schizophrenia in real-life conditions. (endocrine-abstracts.org)

It has been estimated that schizophrenia affects approximately 1% of the adult population in the US and Europe. (europeanpharmaceuticalreview.com)
Schizophrenia is a pervasive neuropsychiatric disease of uncertain cause that affects approximately 1% of the adult population in the United States and Europe. (cdc.gov)

All patients were on antipsychotic medication. (psychiatrist.com)
APA recommends that patients with schizophrenia be treated with an antipsychotic medication and monitored for effectiveness and side effects. (guidelinecentral.com)
APA recommends that patients with schizophrenia whose symptoms have improved with an antipsychotic medication continue to be treated with an antipsychotic medication. (guidelinecentral.com)
APA suggests that patients receive treatment with a long-acting injectable antipsychotic medication if they prefer such treatment or if they have a history of poor or uncertain adherence. (guidelinecentral.com)
APA suggests the following options for patients who have parkinsonism associated with antipsychotic therapy: lowering the dosage of the antipsychotic medication, switching to another antipsychotic medication, or treating with an anticholinergic medication. (guidelinecentral.com)
APA suggests the following options for patients who have akathisia associated with antipsychotic therapy: lowering the dosage of the antipsychotic medication, switching to another antipsychotic medication, adding a benzodiazepine medication, or adding a beta-adrenergic-blocking agent. (guidelinecentral.com)
The mainstay of treatment for schizophrenia is an antipsychotic medication. (wikipedia.org)

We did a cross-sectional study over 8 weeks plex way by such things as physical health, (February-March 2002) on patients with a psychological state, level of independence, clinical diagnoses of schizophrenia atten- social relationships and relationship to ding the main outpatient psychiatric clinic the environment [ 3 ]. (who.int)
Some significant episodes of psychotic symptoms do not fulfill criteria for other diagnoses in the schizophrenia spectrum. (msdmanuals.com)

Our study showed that a significantly higher proportion of patients receiving combined treatment obtained employment or accessed education. (sciencedaily.com)
The study sample was recruited from in-patients at one of four hospitals in central and inner London (Park Royal Centre for Mental Health, Paterson Centre, St Charles' Hospital and St Clement's Hospital). (cambridge.org)
Structural magnetic resonance imaging (MRI) and genetic data of the Mind Clinical Imaging Consortium (MCIC) study of schizophrenia were used to analyse the interaction effects between 1,067,955 single nucleotide polymorphisms (SNPs) and disease status on left STG thickness in 126 healthy controls and 113 patients with schizophrenia. (nih.gov)
Our strongest findings in the GWA study and pathway analysis point towards an involvement of glucose metabolism in left STG thickness reduction in patients with schizophrenia only. (nih.gov)
Our aim was to study the frequency of metabolic syndrome and associated factors in patients with schizophrenia. (psychiatrist.com)
The study group consisted of 35 outpatients with long-term schizophrenia defined by DSM-IV criteria. (psychiatrist.com)
As described in the journal Neuron on Feb. 22, 2012, a small clinical study conducted at the San Francisco VA Medical Center (SFVAMC) and the University of California, San Francisco (UCSF), tested the digital exercises as a new therapy for schizophrenia. (ucsf.edu)
The medial prefrontal cortex is a critical higher-order brain region that supports successful reality-monitoring processes," said Karuna Subramaniam, the study's first author, who worked directly with the patients in the study and analyzed their data. (ucsf.edu)
In this study, we assessed gamma band power in minimally treated patients with schizophrenia, their first-degree relatives and healthy controls during an oddball paradigm performance, as well as the relation between gamma power and cognitive performance. (karger.com)
The study involved 12 patients, all of which had near-daily hallucinatory events. (zmescience.com)
Patients were also able to take the strategies they developed for the study and bring them back to their day to day life. (zmescience.com)
RESULTS: In the present study, 145 patients diagnosed with schizophrenia (mean age 42.2 years (SD ± 13.8)) were included, with 88 (60.7%) being male. (aau.dk)
The association between the explanatory variables and outcome of HS was assessed using multivariable logistic regression.RESULTS: In the present study, 145 patients diagnosed with schizophrenia (mean age 42.2 years (SD ± 13.8)) were included, with 88 (60.7%) being male. (aau.dk)
Patients and staff from mental health centers are helping with this study. (pcori.org)
The study authors concluded, "The case management intervention to encourage participation in colorectal cancer screening was effective for patients with schizophrenia. (ascopost.com)
Objectives The aim of this study was to assess the health-related quality of life (HRQoL) and associated factors among patients with schizophrenia at comprehensive specialised hospitals in Northwest Ethiopia. (bmj.com)
Design and setting A cross-sectional study was conducted among 422 patients with schizophrenia who were followed at comprehensive specialised hospitals in Northwest Ethiopia from 1 June to 30 August 2022. (bmj.com)
Participants All adult patients with schizophrenia who had regular follow-up in the outpatient departments of the selected hospitals were study participants. (bmj.com)
Conclusion and recommendation In this study, the social domain was recorded as having the lowest mean score, which may indicate that patients with schizophrenia could need better psychosocial support. (bmj.com)
One study using the Involvement Evaluation Questionnaire-EU Version (IEQ-EU) showed that the consequences of caring for an individual with depression or schizophrenia were comparable [ 11 ]. (biomedcentral.com)
In one study, patients who had a dedicated observer were less likely to become agitated when they were involved in an individualized therapeutic activity. (ahdbonline.com)
In one study, training that focused specifically on recognizing patient relapses increased staff skills and confidence in implementing these new skills. (ahdbonline.com)
The NDA is based on data from a phase III clinical study designed to evaluate the efficacy, safety and tolerability of the intramuscular formulation as a maintenance treatment in patients with schizophrenia. (europeanpharmaceuticalreview.com)
This study aims to reveal the abnormal amplitude dynamics of electroencephalogram (EEG) oscillations in schizophrenia patients on multiple time scales. (harvard.edu)
In 2006, with the support of a NARSAD Grant, he initiated a pilot study, an 18-month trial in which 60 low-functioning, neurocognitively impaired schizophrenia patients were enrolled to test whether CBT could help them. (bbrfoundation.org)
This study allows for new insights by leveraging first-hand experiences of those with schizophrenia. (uclahealth.org)
The study appears in the September 5 issue of the journal Schizophrenia Bulletin. (uclahealth.org)
Therefore, this study aimed to find out whether cognitive effort-avoidance in patients with schizophrenia can reflect their amotivation. (biomedcentral.com)
In the study, 309 patients with schizophrenia had a one-week open-label treatment with olanzapine, followed by a 12-week double-blind treatment phase in which patients were randomly assigned to receive olanzapine plus placebo (n=75) or olanzapine plus samidorphan in these doses:5 mg (n=80), 10 mg (n=86), and 20 mg (n=68). (psychnews.org)
Reformulations were made in the application format and the presentation of the items in order to assure its semantic equivalence with the original scale, its adaptation to the Brazilian context and its applicability to the target population.We have concluded that this scale is appropriate for the evaluation of the quality of life of family caregivers of schizophrenic patients after a validation study. (bvsalud.org)
The purpose of the present study was to investigate whether HPS4 is associated with cognitive functions in patients with schizophrenia and healthy controls and with the clinical profiles of patients with schizophrenia. (qxmd.com)
In a study that included more than 5000 psychiatric patients and 8000 healthy control persons, investigators found that among schizophrenia patients, particularly those aged 18 to 40 years, rates of sleep disturbances were much higher than in the general population. (medscape.com)
In the current study, the investigators focused on 5046 patients aged 18 to 80 years. (medscape.com)
These patients were compared with 8018 adults from the general population who took part in the Health 2000 study. (medscape.com)
Structure and predictors of in-hospital nursing care leading to reduction in early readmission among patients with schizophrenia in Japan: A cross-sectional study. (bvsalud.org)
For this reason, we previously carried out a approach to medical care, in which the pa- psychometric study on the modified version tient's own views are considered important of the schizophrenia quality of life scale [ 4 ]. (who.int)
Few eligible patients participated in the program during the study period, and overall estimates of effectiveness were low. (cdc.gov)

Schizophrenia is a highly disabling psychiatric disorder with a heterogeneous phenotypic appearance. (nih.gov)
Schizophrenia (SZ) is a severe psychiatric disorder, with a prevalence of 1-2% world-wide and substantial health- and social care costs. (lu.se)

In a 12-month follow-up randomized clinical trial, we aimed to measure the efficacy of a brief family psychoeducation program in terms of reducing relapse risk and improving medication adherence in patients, as well as reducing caregiver burden, depression and increasing knowledge of the illness. (frontiersin.org)
At Mass General, the brightest minds in medicine collaborate on behalf of our patients to bridge innovation science with state-of-the-art clinical medicine. (massgeneral.org)
The Schizophrenia Clinical and Research Program at Massachusetts General Hospital is recognized throughout the world as a leader in evaluating and treating this type of illness. (massgeneral.org)
Families with schizophrenia will be recruited for participation in genetics research to curate a list of genes for future inquiry and collect clinical data that can be used to generate hypotheses about genotype-phenotype connections. (uw.edu)
however, its clinical relevance in schizophrenia remains unknown. (qxmd.com)
We investigated the association of variants of HPS4 with clinical symptoms and cognitive function in Japanese patients with schizophrenia (n = 240) and age-matched healthy control subjects (n = 240) with single nucleotide polymorphisms (SNP)- or haplotype-based linear regression. (qxmd.com)
The new results "shed light" on biological pathways associated with comorbidity between CVD and schizophrenia, said the authors, adding future work could provide insights into mechanisms underlying the comorbidity and could facilitate development of antipsychotics with lower metabolic side effects, which could help prevent comorbid CVD, "thereby helping to mitigate a major clinical and health care problem. (medscape.com)
Multigenetic Pharmacogenomics-Guided Treatment vs Treatment As Usual Among Hospitalized Men With Schizophrenia: A Randomized Clinical Trial. (cdc.gov)
In this randomized clinical trial that included 210 Chinese Han men, patients treated with multigenetic pharmacogenomics-guided treatment had a greater symptom improvement than those treated with treatment as usual after a 6-week treatment, measured as the mean difference in percentage change of Positive and Negative Syndrome Scale score. (cdc.gov)

Therefore, we developed a case management approach with particular focus on colorectal cancer screening for patients with schizophrenia in psychiatric outpatient clinics. (ascopost.com)

For caregivers, the intervention reduced the burden ( p = 0.031), decreased the depression ( p = 0.019), and increased the knowledge on schizophrenia ( p = 0.024). (frontiersin.org)
As confirmed by previous studies, the brief multifamily program (consisting of six sessions over a period of 1.5 months) was found to be effective in improving outcomes for caregivers (e.g., burden, depression, knowledge) and patients (e.g., preventing relapse) in the context of routine care. (frontiersin.org)
They grouped the participants into three distinct patient classes: those with minimal morbidity, depression and medical comorbidity, and SUDs and related conditions. (medscape.com)
However, the depression and medical comorbidity and SUD patient groups also diverged in terms of other outcomes. (medscape.com)

APA recommends that patients with schizophrenia have a documented, comprehensive, and person-centered treatment plan that includes evidence-based nonpharmacological and pharmacological treatments. (guidelinecentral.com)
Learn important facts about Schizophrenia and what you need to know such as: causes, symptoms and treatments for it. (hopkinsmedicine.org)
The bulk of treatments for schizophrenia were developed from observations of individuals who are quite ill or hospitalized, rather than patients who have achieved a level of recovery," Cohen said. (uclahealth.org)
Mental health services need to assess the risk of violence among patients with schizophrenia and provide treatments that directly target antisocial and aggressive behaviour. (researchgate.net)
This new guideline offers psychiatrists an approach to help patients that incorporates effective, evidence-based treatments as well as our patients' preferences and goals," said APA President Jeffrey Geller, M.D., M.P.H. "We encourage all psychiatrists and others who are interested to review the recommendations, which were developed by experts in researching and treating this complicated disorder. (psychiatry.org)
he guideline recommends that patients with schizophrenia have a documented, comprehensive, and person-centered treatment plan that includes evidence-based nonpharmacological and pharmacological treatments. (psychiatry.org)

During 2009-2011, an estimated 382,000 emergency department (ED) visits related to schizophrenia occurred each year among adults aged 18-64 years, with an overall ED visit rate of 20.1 per 10,000 adults. (medscape.com)
H. Lundbeck A/S (Lundbeck) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) announced today that the US Food and Drug Administration (FDA) has determined that a new drug application (NDA) for Otsuka's investigational once-monthly aripiprazole depot formulation for the indication of maintenance treatment of schizophrenia in adults is sufficiently complete to permit a substantive review. (europeanpharmaceuticalreview.com)
In the US, there are approximately 2.2 million adults with schizophrenia, prevalent equally in both genders[1]. (europeanpharmaceuticalreview.com)
Schizophrenia symptoms in teenagers are similar to those in adults, but the condition may be more difficult to recognize. (mayoclinic.org)

Copy number variants (CNVs) affecting the neurexin 1 (NRXN1) gene have been found in a subgroup of patients with schizophrenia (SZ). (elsevierpure.com)
Association of the Hermansky-Pudlak syndrome type 4 (HPS4) gene variants with cognitive function in patients with schizophrenia and healthy subjects. (qxmd.com)

The findings were presented here at the Schizophrenia International Research Society (SIRS) 2018 Biennial Meeting. (medscape.com)

For patients, the family psychoeducation intervention significantly reduced the risk of relapse with a significant effect found at 12 months follow-up ( p = 0.014). (frontiersin.org)
Leptin levels adjusted for BMI in females were significantly higher in patients than in healthy female subjects ( P =0.018). (endocrine-abstracts.org)
The combination of the antipsychotic olanzapine and samidorphan, an experimental agent that acts on opioid receptors in the brain, results in significantly lower weight gain than olanzapine plus placebo in patients with schizophrenia, according to a report in AJP in Advance . (psychnews.org)
In patients with schizophrenia, rs713998 was significantly associated with executive function under the dominant genetic model (P = 0.0073). (qxmd.com)

Globally, about 15%-30% of patients with schizophrenia discharged from inpatient psychiatric admissions are readmitted within 90 days due to exacerbation of symptoms that leads to self -harm, harm to others, or self-neglect . (bvsalud.org)

While the cause is unknown, studies have suggested that there are differences in the brains of patients with schizophrenia. (disabled-world.com)

1 Agitated patients may exhibit aggressive behavior, resulting in harm to themselves, other patients, and healthcare workers. (ahdbonline.com)

APA suggests that patients with schizophrenia who have ongoing contact with family receive family interventions. (guidelinecentral.com)
APA suggests that patients with schizophrenia receive interventions aimed at developing self-management skills and enhancing person-oriented recovery. (guidelinecentral.com)
6 Whenever possible, nonpharmacologic interventions should be implemented in advance of treatment with drugs,6 and patients should be involved in decisions regarding the types of drugs used and the route of administration. (ahdbonline.com)
It will produce the first 3 single-blind randomised controlled trials of psychological interventions to support treatment decision-making in schizophrenia-spectrum disorder. (lancs.ac.uk)

In humans, acute infection with T. gondii can produce psychotic symptoms similar to those displayed by persons with schizophrenia. (cdc.gov)
Patients with less severe psy- chotic and non-psychotic symptoms were also found to have better quality of life. (who.int)

This research aims at making a cross-cultural adaptation of the Schizophrenia Caregiver Quality of Life Questionnaire (S-CGQoL) to the Brazilian context. (bvsalud.org)

The risk of relapse was lower among patients in the combination group, occurring in 14.6 percent of patients in that group and 22.5 percent of patients in the medication-only group. (sciencedaily.com)
In order to successfully treat and manage schizophrenia there needs to be a collaborative and supportive team approach among patients, caregivers and psychiatrists. (disabled-world.com)
The results suggest that metabolic syndrome is common among patients with schizophrenia, and it may be far more common than in general populations. (psychiatrist.com)
Implementing such support services at psychiatric centers can help improve awareness and participation in early cancer screening among patients with mental illnesses. (ascopost.com)
A new questionnaire was developed to assess the extent to which respondents delivered in- hospital nursing care leading to reduction in early readmission among patients with schizophrenia . (bvsalud.org)

The physician universe, sample size, and response rates by physician specialty are shown in table I. Of the participating physicians, 237 saw no patients during their assigned reporting period because of vacations, illness, or other reasons for being temporarily not in practice. (cdc.gov)

The present results provide new insights for cognitive deficits and the underlying neuronal dysfunction in schizophrenia. (harvard.edu)

The findings suggest that risk factors for HS are similar in both the general population and in patients with schizophrenia. (aau.dk)
These findings suggest that patients with schizophrenia can participate in cancer screening to the same extent as the general population, albeit with some assistance. (ascopost.com)
Our findings suggest that caregivers of patients with an ED could benefit from providing adequate assessment and support. (biomedcentral.com)

We surveyed a population of adult patients with PKU and assessed how management, treatment, and lifestyle factors impact their relationship satisfaction. (cdc.gov)

Social outcomes reflect how patients live, function in society and perform their various roles (e.g., having a job, going to school or having friends)," the authors write. (sciencedaily.com)
Thus, the findings support the results from previous studies that patients with schizophrenia receiving combined treatment had better outcomes. (sciencedaily.com)
For patients, family psychoeducation has been effective in improving outcomes in schizophrenia with a better level of global functioning, medication adherence, and a reduction in the use of healthcare resources and the frequency of relapse ( 6 - 8 ). (frontiersin.org)
Efforts in this direction can help decrease cancer-related mortality and improve patient outcomes in such populations. (ascopost.com)
Outcomes as measured on the Global Assessment Scale, a standard scale for measuring overall functioning, showed that the CBT patients made clinically significant improvements in functioning and in reduction of positive symptoms, which were not seen in the patients in the standard-treatment-only group. (bbrfoundation.org)

Cancer is a leading cause of mortality in patients with mental illnesses. (ascopost.com)
Social stigma continues to be a serious problem for those affected by schizophrenia and other mental illnesses. (uclahealth.org)

A higher proportion of the counseled patients also underwent screening for other cancers compared to the usual treatment group-notably, participation in screening for lung cancer increased. (ascopost.com)
Although the injury severity did not differ from the comparison group, these patients had longer lengths of hospitalization, a greater proportion of injuries to the back and spine, and a greater proportion required extended care in an intermediate care facility (not a jail) following discharge. (cdc.gov)
Little is known about the proportion of eligible VA patients ("candidates") who participate in the program, the characteristics of participants, or the program's effectiveness. (cdc.gov)

Nonetheless, a major limitation in schizophrenia research remains the lack of clinically relevant animal models, which in turn hampers the development of novel effective therapies for the patients. (lu.se)

Anatomy17

Diseases16

Chemicals and Drugs19

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Psychiatry and Psychology77

Phenomena and Processes31

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena5

Humanities1

Information Science5

Named Groups2

Health Care18

Individuals with schizophrenia8

Diagnosis16

Psychosis9

Symptoms of schizophrenia5

Psychiatry6

Causes of schizophre2

Abstract4

Chronic9

Hallucinations6

Bipolar Disorder10

Disorders14

Methods3

Clozapine4

Superior tempo1

Caregivers of patients with schizophrenia3

Phenotypes4

Delusions1

Approximately 24 million people1

Impact of schizophrenia1

Researchers12

Person with schizophrenia2

Deficits in schizophrenia2

People35

Schizoaffective Disorder2

Cognition4

Stable schizophrenia1

Affects2

Antipsychotic medication7

Diagnoses2

Study37

Psychiatric disorder2

Clinical9

Outpatient clinics1

Depression4

Treatments6

Adults4

Variants2

20181

Significantly4

Inpatient1

Brains1

Behavior1

Interventions4

Psychotic symptoms2

Aims1

Among patients5

Specialty1

Cognitive deficits1

Findings suggest3

Adult patients1

Outcomes5

Mental illnesses2

Proportion3

Clinically1