Necrosis11
- Subcutaneous fat necrosis of the newborn is a rare form of lobular panniculitis occurring in newborns that is usually self-remitting and non-recurring. (wikipedia.org)
- It has been suggested that the brown fat seen in newborns is more sensitive to hypoxic injury than fat seen in adults, and that such hypoxia, usually in the context of a complicated birth, leads to the fat necrosis. (wikipedia.org)
- The infant is also at risk for subcutaneous fat necrosis (SCFN) as a result of asphyxia, a phenomenon seen before cooling was instituted. (medscape.com)
- Decreased circulation to the subcutaneous tissue creates hypoxia and hypothermia, leading to the inflammation and necrosis of fat tissue. (medscape.com)
- These include subcutaneous fat necrosis of the newborn (SCFN), poststeroid panniculitis, and sclerema neonatorum. (contemporarypediatrics.com)
- 6 Subcutaneous fat necrosis of the newborn appears in full-term infants and may be associated with perinatal complications. (contemporarypediatrics.com)
- Subcutaneous fat necrosis of the newborn is characterized by a radial pattern of needle-shaped crystals on histology. (contemporarypediatrics.com)
- The lack of a granulomatous inflammation and the absence of fat necrosis help distinguish sclerema neonatorum from subcutaneous fat necrosis of the newborn (SCFN). (medscape.com)
- Fretzin DF, Arias AM. Sclerema neonatorum and subcutaneous fat necrosis of the newborn. (medscape.com)
- Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases. (medscape.com)
- Del Pozzo-Magaña BR, Ho N. Subcutaneous Fat Necrosis of the Newborn: A 20-Year Retrospective Study. (medscape.com)
Sclerema1
- [ 36 ] However, sclerema is a disorder of the subcutaneous fat that appears first on the thighs and/or buttocks, then spreads to other body surface areas with the exception of the palms, soles, and genitalia. (medscape.com)
Panniculitis5
- Cold panniculitis is a phenomenon that occurs primarily in infants and young children due to a higher proportion of saturated fats in subcutaneous fat compared with older children and adults. (contemporarypediatrics.com)
- A lobular panniculitis with a lymphocytic and histiocytic inflammatory infiltrate is present at the junction of the dermis and subcutaneous fat. (contemporarypediatrics.com)
- 6 Although benign, SCFN should be differentiated from cold panniculitis due to the potential for metabolic derangements, specifically hypercalcemia. (contemporarypediatrics.com)
- 2 Unlike cold panniculitis wherein infiltrates are limited to the upper subcutis, inflammation in SCFN involves the entire subcutaneous fat layer. (contemporarypediatrics.com)
- Post-steroid panniculitis can appear identical to SCFN on biopsy but is easily distinguished with clinical correlation of high dose steroid use. (contemporarypediatrics.com)
Inflammation2
- [ 36 ] The condition is an inflammation of the subcutaneous fat tissue that typically develops during the first week of life. (medscape.com)
- The subcutaneous fat may appear normal or may have only sparse inflammation, which, when present, consists of lymphocytes, histiocytes, and multinucleated giant cells. (medscape.com)
Infants1
- Follow-up of infants with SCFN should include weekly calcium levels until the lesions completely resolve to identify those infants at risk. (medscape.com)
Complications1
- The possibility of such complications necessitates clinical monitoring of patients with SCFN. (contemporarypediatrics.com)
Hypercalcemia1
- however, the infant remains at risk for hypercalcemia as mentioned above (see Table 4 ) because by-products of the SCFN is reabsorbed and liquefied. (medscape.com)
Adults1
- Fat mass and lipid profile in young adults born preterm. (medscape.com)
Short1
- 1 Saturated fats become solid with cold exposure at a relatively higher temperature than unsaturated fats, leading to the potential for fat crystallization and adipocyte damage with short exposures to cold. (contemporarypediatrics.com)