• Bend the tip of a syringe needle by pushing its tip on a steel scalpel blade handle. (jove.com)
  • Manual microdissection has been used for decades [ 4 , 5 ] and is typically performed with a dissecting microscope and a hand held device such as needle or scalpel, which typically limits accuracy to +/- 200 microns, or a micromanipulator, where recovery of small groups of cells can be achieved. (medscape.com)
  • [ 6-9 ] Manual microdissection is tedious and time consuming, particularly when using micromanipulators, tissue retrieval on a needle can be tricky and unreliable, and process documentation is suboptimal. (medscape.com)