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  • possessing pharmacological c
  • Differentiated PC12 cells have a small component of Ca2+ clearance possessing pharmacological characteristics consistent with secretory pathway Ca2+ ATPase (SPCA), potentially residing on Golgi and/or secretory granules. (nih.gov)
  • inhibition
  • One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. (ebi.ac.uk)
  • The selective inhibition of serotonin-induced contractions of rabbit cerebral vascular smooth muscle by calcium antagonistic dihydropyridines: An investigation of the mechanism of action of nimodipine. (springer.com)
  • Mechanism
  • Schramm M, Towart R, Kazda S, Thomas G, Franckowiack G (1984) Calcium-agonism, a new mechanism for positive inotropy: haemodynamic effects and mode of action of BAY K8644. (springer.com)
  • The Mechanism of Gated Calcium Transport Across Biological Membranes presents the proceedings of a symposium, which was an unprecedented attempt to bring together diverse groups working on various aspects of the problem of gated Ca2+ transport. (elsevier.com)
  • rabbit
  • Schuemann HJ, Goerlitz BD, Wagner J (1975) Influence of papaverine, D600 and nifedipine on the effects of noradrenaline and calcium on the isolated aorta and mesenteric artery of the rabbit. (springer.com)
  • Contraction
  • Contributes to calcium sequestration involved in muscular excitation/contraction. (abcam.com)
  • i know ATP is involved in the muscle CONTRACTION with the myosin binding heads, but kaplan specifically says calcium entering muscle cell. (studentdoctor.net)
  • Neurons
  • Our results indicate that Ca2+ transport in undifferentiated PC12 cells is quite unlike transport in adrenal chromaffin cells, for which they often are considered models.Transport in both cell states more closely resembles that of sympathetic neurons, for which differentiated PC12 cells often are considered models.Comparison with other cell types shows that different cells emphasize different Ca2+ transport mechanisms. (nih.gov)
  • Transport in both cell states more closely resembles that of sympathetic neurons, for which differentiated PC12 cells often are considered models. (nih.gov)
  • It discusses such topics as the general properties of gated calcium transport, development of calcium channels in the cleavage-arrested embryo of a certain ascidian, and calcium currents in mammalian neurons. (elsevier.com)
  • type
  • Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (abcam.com)
  • The cytoplasmic loops of the P-type ATPases form three separate modules, commonly named the A, P and N-domains [ PMID: 15448704 ]. (ebi.ac.uk)
  • Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes. (ebi.ac.uk)
  • genes
  • Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences. (springer.com)