AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
AKR murine leukemia virusLeukemia Virus, MurineMice, Inbred AKRMoloney murine leukemia virusAvian Sarcoma VirusesSarcoma Viruses, MurineFriend murine leukemia virusKirsten murine sarcoma virusLeukemia, ExperimentalGenes, ViralAlpharetrovirusHarvey murine sarcoma virusHelper VirusesAbelson murine leukemia virusCell Transformation, ViralRNA, ViralSarcomaDNA, ViralLeukemia Virus, FelineRNA-Directed DNA PolymeraseBase SequenceRauscher VirusVirus ReplicationRetroviridae InfectionsCell LineLeukemia Virus, BovineRetroviridaeGammaretrovirusMolecular Sequence DataViral ProteinsGenome, ViralSarcoma Viruses, FelineDefective VirusesReceptors, VirusLeukemiaNucleic Acid HybridizationMoloney murine sarcoma virusGene Products, gagRous sarcoma virusRNA VirusesTumor Virus InfectionsMink Cell Focus-Inducing VirusesSarcoma, ExperimentalVirus IntegrationProvirusesVirus AssemblyAmino Acid SequenceGenomeRepetitive Sequences, Nucleic AcidCell Transformation, NeoplasticVirus CultivationMice, Inbred StrainsOncogenic VirusesGenetic VectorsSarcoma, AvianVirionRecombination, GeneticVaccinia virusMinkAntigens, ViralLeukemia, Myeloid, AcuteViral Envelope ProteinsLeukemia Virus, Gibbon ApeAvian leukosis virus3T3 Cells
HumanLungMouseWork
Human5
  • He is known for his groundbreaking work on HIV/AIDS and the human genome. (wikipedia.org)
  • He was a founder chairman and CEO of Human Genome Sciences, a company that pioneered the application of genomics to drug discovery. (wikipedia.org)
  • External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. (lookformedical.com)
  • Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. (lookformedical.com)
  • Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2 . (lookformedical.com)
Lung5
  • AB - The pneumotropism of Sendai virus in mice was studied in relation to the activation and replication of the virus in the lung. (nih.gov)
  • Inactive Sendai virus grown in LLC-MK(2) cells, which possessed an uncleaved precursor glycoprotein, F, and was noninfectious to tissue culture cells, neither grew nor caused pathological changes in the lung of mice. (nih.gov)
  • When trypsin treatment was made which cleaved F into F(1) and F(2) subunits, the virus became activated so that it could initiate replication in the bronchial epithelium of the lung. (nih.gov)
  • The progeny virus, however, remained inactive, and the replication was limited to a single cycle, which resulted in the limited lung lesion. (nih.gov)
  • The overall results suggest that some activating mechanism for the progeny virus of wild-type Sendai virus exists in the lung of mice and the principle (activator) responsible for this phenomenon has a character similar to trypsin. (nih.gov)
Mouse1
  • PMID- 6299951 TI - Pneumotropism of Sendai virus in relation to protease-mediated activation in mouse lungs. (nih.gov)
Work3
  • He is known for his groundbreaking work on HIV/AIDS and the human genome. (wikipedia.org)
  • He was at the National Institute of Allergy and Infectious Diseases and had a Branch, or a Laboratory, consisting of a number of well known investigators, amongst which was Wally Rowe and, in his lab, Janet Hartley, who were pretty well known for work in some of the murine viruses. (nih.gov)
  • We were doing work on enteric viruses in water and sewage and, at that time, I was also collecting fecal specimens from Albert Sabin's polio vaccine experiments to determine what quantities of Poliovirus were in feces, and we were using his vaccine strains in his volunteers as some indication of what you could find in raw feces. (nih.gov)