Loading...
  • recombination
  • Coffin JM (1979) Structure, replication, and recombination of retrovirus genomes: some unifying hypotheses. (springer.com)
  • These include reverse transcription and recombination, as well as genome encapsidation. (biomedcentral.com)
  • By use of the same forced recombination system, we have now found recombinant proviruses of different structures, suggesting that PBS knockout vectors may be rescued through initial priming on endogenous virus RNA, read-through of the mutated PBS during minus-strand synthesis, and subsequent second-strand transfer mediated by the R-U5 complementarity of the plus strand and the extended minus-strand DNA acceptor template. (asm.org)
  • Reverse transcription-mediated recombination may involve endogenous virus-like elements, as seen in studies of various replication-defective retroviral mutants ( 6 , 7 , 9 , 31 , 32 , 34 , 51 ). (asm.org)
  • vitro
  • Characterization of nerve growth factor-dependent herpes simplex virus latency in neurons in vitro. (asm.org)
  • replication
  • These ERVs affect retrovirus-induced disease in a number of ways, including manipulation of the immune response, inhibition or facilitation of entry or other steps of virus replication, or as participants in the generation of infectious pathogenic viruses. (springer.com)
  • The recognition of the importance of Rous's discovery after such a long delay was largely owing to the cell transformation assay in monolayer culture of chick embryo fibroblasts reported by Temin & Rubin [ 7 ] in 1958 which enabled quantitative experimental studies of virus replication and cell transformation. (royalsocietypublishing.org)
  • Structures of herpes simplex virus type 1 genes required for replication of virus DNA. (asm.org)
  • polymerase
  • The CD8+ cell non-cytotoxic antiviral response affects RNA polymerase II-mediated human immunodeficiency virus transcription in infected CD4+ cells. (ucsf.edu)
  • transcription
  • In agreement with the essential role of the PBS in initiation and completion of reverse transcription ( 35 , 47 , 62 ), we previously observed a strong restriction in transduction of Akv murine leukemia virus (MLV) vectors with PBSs having only partial (PBS-XXX) or no [PBS-UMU and PBS-Met(i)int] homology with the 3′ end of any known murine tRNA molecule ( 32 ). (asm.org)
  • adenovirus
  • Bachenheimer S., Darnell J. E. Hybridization of mRNA from adenovirus - transformed cells to segments of the adenovirus genome. (medkursor.ru)
  • protein
  • Mapping of functional and antigenic domains of the alpha 4 protein of herpes simplex virus 1. (asm.org)
  • The avian erythroblastosis virus erbA oncogene encodes a DNA-binding protein exhibiting distinct nuclear and cytoplasmic subcellular localizations. (asm.org)
  • Charge microheterogeneity of the major capsid protein of polyoma virus. (asm.org)
  • Characterization of a DNA-protein complex and capsomere subunits derived from polyoma virus by treatment with ethyleneglycol-bis-N,N'-tetraacetic acid and dithiothreitol. (asm.org)
  • purification
  • Quntaka R. V., Bishop J. M., Varmus H. E. Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis. (medkursor.ru)
  • thymus
  • Expression of mouse mammary tumor virus superantigen mRNA in the thymus correlates with kinetics of self-reactive T-cell loss. (springer.com)
  • gene
  • Benjamin T. L. Tumor viruses and cellular gene expression. (medkursor.ru)
  • Functional mapping of Autographa california nuclear polyhedrosis virus genes required for late gene expression. (asm.org)
  • Vaccinia virus-encoded ribonucleotide reductase: sequence conservation of the gene for the small subunit and its amplification in hydroxyurea-resistant mutants. (asm.org)
  • characterization
  • Isolation and preliminary characterization of temperature-sensitive mutants of encephalomyocarditis virus. (asm.org)
  • Biologic, serologic, and molecular characterization of several HIV-1 and HIV-2 strains has revealed their extensive heterogeneity and how viruses can evolve differently in the same individual in the immune system, bowel, and the brain. (ucsf.edu)
  • tumour
  • Kaschka-Dierich C, Adams A., Klein G. Intracellular forms of Epstein - Barr virus DNA in human tumour ceils in vivo. (medkursor.ru)
  • He postulated that RNA tumour viruses made DNA copies which then integrated into host chromosomal DNA, analogous to integration of prophage in bacteria. (royalsocietypublishing.org)
  • Indeed, germ-line integration has not yet been described for DNA tumour viruses, although we now know that it occasionally occurs with human herpesvirus 6 [ 9 , 10 ]. (royalsocietypublishing.org)
  • polymerases
  • Dextran sulfates as a contaminant of DNA extracted from concentrated viruses and as an inhibitor of DNA polymerases. (asm.org)
  • Isolation
  • That was the year that Peyton Rous was awarded the Nobel Prize for Medicine or Physiology for the isolation of his eponymous virus published in 1911, representing a record 55 year incubation period between reporting a discovery and the award [ 6 ]. (royalsocietypublishing.org)
  • species
  • Within a species, the viruses isolated can display considerable diversity of biological properties. (springer.com)
  • Herpes simplex virus mRNA species mapping in EcoRI fragment I. (asm.org)
  • herpes
  • Biegeleisen K., Rush M. G. Association of herpes simples virus type I DNA with host chromosomal DNA during productive infection. (medkursor.ru)
  • Effect of tunicamycin on the synthesis of herpes simplex virus type 1 glycoproteins and their expression on the cell surface. (asm.org)
  • Mapping early transcripts of herpes simplex virus type 1 by electron microscopy. (asm.org)
  • tumor cells
  • Brugge J. S., Purchio A. F., Erikson R. L. The distribution of virus - specific RNA in RSV - induced hamster tumor cells. (medkursor.ru)
  • sequence
  • Alizon M, Wain-Hobson S, Montagnier L, Sonigo P (1986) Genetic variability of the AIDS virus: nucleotide sequence analysis of two isolates from African patients. (springer.com)
  • Joseph D. R., Ihle J. N. Comparison of sequence homology of Poly (A) and nonpoly (A) containing 34S RNA of AKR murine leukemia virus. (medkursor.ru)
  • Sequence relationships between the genome segments of human and animal rotavirus strains. (asm.org)
  • Mapping
  • Comparison of a transforming and a nontransforming virus by partial denaturation mapping of their DNAs. (asm.org)
  • Type
  • Kurth R., Bosch V., Bolognesi D. P. Polypeptides of endogenous avian С - type viruses: their detection in the plasma membrane of normal and infected cells. (medkursor.ru)
  • Evolutionarily conserved epitopes on human immunodeficiency virus type 1 (HIV-1) and feline immunodeficiency virus reverse transcriptases detected by HIV-1-infected subjects. (ucsf.edu)
  • notion
  • However, this implies that dimerization must be a prerequisite for genome encapsidation, a notion that has been debated for many years. (biomedcentral.com)