• The saphenous vein is often used for autotransplantation in coronary artery bypass operations, when arterial grafts are not available or many grafts are required. (promocell.com)
  • Drug-eluting stents versus bare-metal stents in saphenous vein grafts: a double-blind, randomised trial. (acc.org)
  • Jeger RV, Möbius-Winkler S. Stents in saphenous vein grafts. (acc.org)
  • BACKGROUND: Approximately 15% of saphenous vein grafts (SVGs) occlude during the first year after coronary artery bypass graft surgery (CABG) despite aspirin use. (eur.nl)
  • Conclusions All but one patent internal mammary artery or radial artery grafts had perfect patency and had superior perfect patency and overall patency compared to saphenous vein grafts. (researchsquare.com)
  • Long-term comparison of everolimus-eluting stents with sirolimus- and paclitaxel-eluting stents for percutaneous coronary intervention of saphenous vein grafts. (ox.ac.uk)
  • Purpose: To determine why some vein grafts fail, we prospectively studied the relationship between the histologic condition of the greater saphenous vein (GSV) at the time of grafting and subsequent stenosis of the vein graft. (wustl.edu)
  • Four of 24 (17%) failed or failing grafts had evidence of vein wall calcification at the time of vein grafting. (wustl.edu)
  • The aim of the study was to assess histological representative features of saphenous vein reconstruction in aging as well as to establish optimal patients' age limits applicable for optimal selection of grafts. (archivesofmedicalscience.com)
  • Tissue was obtained from coronary arteries without prior instrumentation (primary lesions, n = 31), aortocoronary saphenous vein bypass grafts with primary lesions (n = 8), coronary arteries with lesions developing after prior balloon angioplasty or mechanical atherectomy (reste-notic lesions, n = 30) and vein bypass grafts with restenotic lesions (n = 4). (elsevierpure.com)
  • These lesions frequently contained cholesterol crystals (45% of coronary arteries, 50% of vein grafts) and calcium deposits (65% of coronary arteries, 38% of vein grafts). (elsevierpure.com)
  • Objective: We sought to compare the characteristics and outcomes of patients who were enrolled versus those who were not enrolled in the Stenting of Saphenous Vein Grafts (SOS) randomized controlled trial. (elsevierpure.com)
  • 4. Two or more vein grafts to native vessels having at least 75% stenosis and comparable runoff. (who.int)
  • The small saphenous vein may become varicose. (wikipedia.org)
  • chapter 44 - Surgical Treatment of Varicose Veins", Comprehensive Vascular and Endovascular Surgery (Second Edition), Philadelphia: Mosby, pp. 756-770, doi:10.1016/b978-0-323-05726-4.00046-9, ISBN 978-0-323-05726-4, retrieved 2020-11-25 Goldman, Mitchel P. (wikipedia.org)
  • Varicose veins occur when one or more valves stop working, creating distended areas where blood has backed up into smaller veins just under the surface of the skin. (healthline.com)
  • The great saphenous vein is sometimes stripped out of the leg to eliminate varicose veins. (healthline.com)
  • In the surgical treatment of varicose veins, diseased veins are simply removed through tiny skin punctures (1 cm). (dk-allianz.de)
  • Changes in health-related quality of life after ultrasound-guided foam sclerotherapy for great and small saphenous varicose veins. (qxmd.com)
  • Health-related quality of life (HRQOL) improves after superficial venous surgery for varicose veins, but the effect of ultrasound-guided foam sclerotherapy on HRQOL is unknown. (qxmd.com)
  • The aim of this study was to determine changes in HRQOL after ultrasound-guided foam sclerotherapy for varicose veins. (qxmd.com)
  • Consecutive patients undergoing ultrasound-guided foam sclerotherapy for varicose veins were sent the Short Form 12 (SF-12) questionnaire, a generic measure of HRQOL, and the Aberdeen Varicose Vein Symptom Score (AVSS) questionnaire, a disease-specific measure of HRQOL, 1 week before treatment and 1, 6, and 12 months after treatment. (qxmd.com)
  • Of these, 24% had had previous superficial venous surgery, and 66% were CEAP C(2-3) (uncomplicated varicose veins). (qxmd.com)
  • Ultrasound-guided foam sclerotherapy for great and small saphenous varicose veins leads to significant improvements in generic and disease-specific HRQOL for at least 12 months after treatment. (qxmd.com)
  • Varicose veins are an early manifestation of chronic venous insufficiency. (medscape.com)
  • Although the risk factors associated with varicose veins are well described, the basic pathophysiology leading to venous valvular incompetence, and thus, varicosities are less well known. (medscape.com)
  • However, cosmetics aside, the leg fatigue and heaviness that is associated with chronic venous insufficiency in the presence of varicose veins can be disabling. (medscape.com)
  • Traditionally, varicose veins were removed with multiple stab incisions and hook phlebectomy. (medscape.com)
  • The introduction of transilluminated-powered phlebectomy has allowed for removal of large clusters of varicose veins using fewer stab incisions and less procedural time. (medscape.com)
  • Image courtesy of Rustempasic N, Cvorak A, Agincic A. Outcome of endovenous laser ablation of varicose veins. (medscape.com)
  • Much about the etiology of varicose veins remains unknown. (medscape.com)
  • Although few studies document the natural history of varicose veins (shown) , superficial venous insufficiency is considered to be progressive over time, typically beginning as reticular veins or corona phlebectatica ("corona"), developing into isolated calf varicosities and, eventually, resulting in a tortuous and distended great saphenous vein. (medscape.com)
  • We published some years ago a new approach for the treatment of varicose veins (VVs) called ASVAL (Ambulatory Selective Varices Ablation under Local anesthesia), which showed that single phlebectomies improve the hemodynamics of the venous system and the clinical outcomes even in presence of a saphenous vein (SV) reflux. (veindirectory.org)
  • In presence of saphenous reflux, and up until a certain stage of the disease, first-line therapy should include ablation of the varicose reservoir (VR) and not stripping/ablation of the saphenous vein for which the reflux is potentially reversible (fig. 1). (veindirectory.org)
  • 5 Thanks to new publications about ASVAL, the European guidelines published in 2015 recommended the performance of ASVAL with a class/level of evidence 2B, saying that "in selected patients, with less evolved varicose veins (C2-C3) single phlebectomies with preservation of the saphenous trunk should be considered. (veindirectory.org)
  • Most of the varicose veins procedures are performed in private practice and it is hard to randomize a patient between ablation/ conservation of the SV in private practice. (veindirectory.org)
  • These drugs are injected into varicose veins to produce endothelial destruction resulting in formation of a fibrotic cord. (medscape.com)
  • Polidocanol is a sclerosing agent indicated for uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1-3 mm in diameter) in lower extremities. (medscape.com)
  • Piazza G. Varicose veins. (medscape.com)
  • Racette S, Sauvageau A. Unusual sudden death: two case reports of hemorrhage by rupture of varicose veins. (medscape.com)
  • Association of Varicose Veins With Incident Venous Thromboembolism and Peripheral Artery Disease. (medscape.com)
  • Computed tomographic venography for varicose veins of the lower extremities: prospective comparison of 80-kVp and conventional 120-kVp protocols. (medscape.com)
  • Nael R, Rathbun S. Treatment of varicose veins. (medscape.com)
  • Minimally invasive techniques in the treatment of saphenous varicose veins. (medscape.com)
  • Muller-Buhl U, Leutgeb R, Engeser P, Achankeng EN, Szecsenyi J, Laux G. Varicose veins are a risk factor for deep venous thrombosis in general practice patients. (medscape.com)
  • Double-blind prospective comparative trial between foamed and liquid polidocanol and sodium tetradecyl sulfate in the treatment of varicose and telangiectatic leg veins. (medscape.com)
  • Brooks M. FDA OKs New Minimally Invasive Treatment for Varicose Veins. (medscape.com)
  • Mao J, Zhang C, Wang Z, Gan S, Li K. A retrospective study comparing endovenous laser ablation and microwave ablation for great saphenous varicose veins. (medscape.com)
  • Radiofrequency ablation of varicose veins: Best practice techniques and evidence. (medscape.com)
  • Prevention of edema and flight microangiopathy with Venoruton (HR), (0-[beta-hydroxyethyl]-rutosides) in patients with varicose veins. (medscape.com)
  • Vein stripping is surgery to remove varicose veins in the legs. (medlineplus.gov)
  • Varicose veins are swollen, twisted, and enlarged veins that you can see under the skin. (medlineplus.gov)
  • The valves in varicose veins are either damaged or missing. (medlineplus.gov)
  • This helps treat varicose veins. (medlineplus.gov)
  • Today, doctors are rarely performing vein stripping surgeries because there are newer, non-surgical ways to treat varicose veins that don't require general anesthesia and are done without an overnight hospital stay. (medlineplus.gov)
  • Iafrati MD. Varicose veins: surgical treatment. (medlineplus.gov)
  • The goal of the trial was to evaluate drug-eluting stents (DES) compared with bare-metal stents (BMS) among patients with saphenous vein graft lesions undergoing percutaneous coronary intervention (PCI). (acc.org)
  • Whether this benefit is maintained among patients with saphenous vein graft (SVG) disease remains controversial. (ox.ac.uk)
  • Primary Human Saphenous Vein Endothelial Cells isolated from saphenous veins from single donors. (promocell.com)
  • Here, we describe the isolation, characterization, and expansion of human saphenous vein endothelial cells (hSVECs). (gentaurpub.com)
  • CHAPTER 32 - Treatment of Small Saphenous Vein Reflux", The Vein Book, Burlington: Academic Press, pp. 291-298, doi:10.1016/b978-012369515-4/50035-1, ISBN 978-0-12-369515-4, retrieved 2020-11-19 "VEINSURG - Duplex Ultrasound Investigation of the Veins in Chronic Venous Disease of the Lower Limbs-UIP Consensus Document. (wikipedia.org)
  • The great saphenous vein (GSV) of such patients was investigated using duplex scanning (DS) to verify whether a reflux could occur in certain circumstances, ie, at the end of the day in an orthostatic position. (phlebolymphology.org)
  • C0s, En, An, Pn patients may present with a transient reflux in the GSV that occurs at the end of day. (phlebolymphology.org)
  • Treatment with MPFF (1000 mg of MPFF once a day in the morning for 2 months) resulted in the elimination of the evening GSV reflux in most of the treated patients, decrease in vein diameter and also resulted in beneficial effects on symptom relief and quality of life improvement. (phlebolymphology.org)
  • Foam sclerotherapy is considered an acceptable method to treat great saphenous vein (GSV) insufficiency, promoting occlusion of its trunk and eradicating reflux. (bvsalud.org)
  • The treatment of superficial vein reflux has evolved in the past 10 years making open surgical ligation and stripping of the great saphenous vein largely a historic procedure. (medscape.com)
  • Before the emergence of saphenous reflux, early treatment of VVs would be useful in order to prevent it spreading to the SV. (veindirectory.org)
  • Saphenous stripping or ablation would only be indicated in cases where saphenous reflux seems to be irreversible. (veindirectory.org)
  • Saphenous vein cutdown is indicated for the purpose of emergency venous access (when attempts to gain access via peripheral or percutaneous routes have failed). (medscape.com)
  • Can direct stenting in selected saphenous vein graft lesions be considered an alternative to percutaneous intervention with a distal protection device? (gwu.edu)
  • Impact of internal mammary artery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft. (musc.edu)
  • Retrograde recanalization of left main from saphenous vein graft supported by percutaneous Impella Recover LP 2.5 assist device. (unicatt.it)
  • Can direct stenting in selected saphenous vein graft lesions be consid" by T. Okabe, J. Lindsay et al. (gwu.edu)
  • In conclusion, MOCA is proven to be effective and safe for treating greater saphenous vein insufficiency," Reijnen said. (vascularnews.com)
  • Sheath-Based Combined Foam Sclerotherapy to Promote Management of Extensive Insufficiency of the Great Saphenous Vein in Venous Ulcers. (bvsalud.org)
  • The saphenous vein is generally acceptable as a conduit in the absence of other vascular pathologies in the leg (varicosities in the vein, venous insufficiency, previous deep vein thrombosis [DVT], or small lumen diameter) or overlying infection. (medscape.com)
  • The POPular CABG trial (The Effect of Ticagrelor on Saphenous Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting Surgery) investigated whether ticagrelor added to standard aspirin improves SVG patency at 1 year after CABG. (eur.nl)
  • Saphenous vein remains used as a CABG conduit despite the reduced long-term patency compared to arterial conduits. (gentaurpub.com)
  • The abrupt increase of hemodynamic stress associated with the graft arterialization results in vascular damage, especially the endothelium, that may influence the low patency of the saphenous vein graft (SVG). (gentaurpub.com)
  • As CABG conduits, the saphenous veins have an 80-90% early patency rate, which decreases to 50% at 10 years. (medscape.com)
  • The small saphenous vein (also short saphenous vein or lesser saphenous vein) is a relatively large superficial vein of the posterior leg. (wikipedia.org)
  • also referred to as the lesser or short saphenous vein) does not directly anastomose with the GSV. (medscape.com)
  • The small (short) saphenous vein (SSV) is located 1 cm posterior to the lateral malleolus, runs centrally up the posterior calf, and drains into the popliteal vein. (medscape.com)
  • The origin of the small saphenous vein, (SSV) is where the dorsal vein from the fifth digit (smallest toe) merges with the dorsal venous arch of the foot, which attaches to the great saphenous vein (GSV). (wikipedia.org)
  • The small saphenous vein may be harvested for transplant to elsewhere in the body, such as in coronary artery bypass surgery. (wikipedia.org)
  • also referred to as the greater or long saphenous vein) is the vessel most commonly used for the venous cutdown. (medscape.com)
  • they are typically found in the calf but may also occur in the thigh, corresponding to the course of the long saphenous vein. (medscape.com)
  • The great (long) saphenous vein (GSV) is located 2 cm anterior to the medial malleolus, traverses the tibia, and ascends posteriorly up the tibial border before emptying into the femoral vein. (medscape.com)
  • Endovenous ablation using catheter-based techniques achieve vein closure with minimal surgical risk. (medscape.com)
  • We have 10 years of successful experience in daily practice, with a continuous increase in favor of ASVAL compared to saphenous ablation (fig. 2). (veindirectory.org)
  • Fig. 2: Evolution of ASVAL and stripping/ endothermal ablation procedures from 2003 at the Riviera Vein Institute. (veindirectory.org)
  • Patients with saphenous vein graft lesions undergoing PCI were randomized to DES (n = 292) versus BMS (n = 305). (acc.org)
  • DIVA is one of the largest trials on the topic and revealed that the use of BMS for saphenous vein graft lesions (for potential cost savings) could be considered. (acc.org)
  • Restenotic lesions were characterized by an increased proportion of loose fibroproliferative tissue (45% of coronary artery intima, 35% of vein graft intima). (elsevierpure.com)
  • The GSV, which is the longest vein in the body, originates at the ankle as a continuation of the medial marginal vein of the foot and ends at the femoral vein within the femoral triangle. (medscape.com)
  • In the thigh, the GSV courses anterolaterally through the fossa ovalis, where it joins the femoral vein approximately 4 cm below the inguinal ligament. (medscape.com)
  • It arises from the dorsal venous arch at the top (dorsum) of the foot and drains into the femoral vein, the main deep vein for the leg. (healthline.com)
  • Before reaching the femoral vein, it collects blood from several smaller veins, including the superficial gastric, superficial circumflex iliac, and superficial pudendal. (healthline.com)
  • The purpose of the great vein is delivery of blood from the ankle, lower leg, and thigh to the femoral vein. (healthline.com)
  • The femoral vein is located in the upper thigh and pelvic region of the human body. (healthline.com)
  • In more than 50% of the general population, superficial venous disease appears in the form of "spider" or reticular veins, but in approximately 20%-25% of the population, the disease can progress to visible varicosities at its extremes, such as ulceration or skin changes. (medscape.com)
  • Reticular veins are typically small (1-3 mm), highly visible, and often pose a cosmetic problem for patients. (medscape.com)
  • Background Where each patient has all three conduits of internal mammary artery (IMA), saphenous vein graft (SVG) and radial artery (RA), most confounders affecting comparison between conduits can be mitigated. (researchsquare.com)
  • Our institutional practice had relatively few patients that received all three conduits of internal mammary artery (IMA), radial artery (RA) and saphenous vein (SVG) at the same time, with subsequent experience being predominantly total arterial revascularization [1, 2]. (researchsquare.com)
  • 3. Here we tested the hypothesis that RIG200 and S-nitrosoglutathione (GSNO) have prolonged, NO-mediated effects in human saphenous vein (SV) and internal mammary artery (IMA), compared with glyceryl trinitrate (GTN) and sodium nitroprusside (SNP). (uhi.ac.uk)
  • Severe Functional Tricuspid Stenosis Secondary to a Giant Saphenous Vein Bypass Graft Aneurysm. (qxmd.com)
  • We report a patient with saphenous vein graft aneurysm who presented with abdominal pain due to compression of the adjacent liver 43 years after the coronary bypass operation. (elsevierpure.com)
  • Usually, it drains into the popliteal vein, at or above the level of the knee joint. (wikipedia.org)
  • Sometimes, the SSV joins the common gastrocnemius vein before draining in the popliteal vein. (wikipedia.org)
  • Sometimes, it does not make contact with the popliteal vein, but goes up to drain in the GSV at a variable level. (wikipedia.org)
  • Instead of draining in the popliteal vein, it can merge with the Giacomini vein and drain in the GSV at the superior 1/3 of the thigh. (wikipedia.org)
  • Popliteal fossa Cross-section through middle of leg Nerves of the dorsum of the foot Veins of the leg]] Ricci, Stefano (2017-01-01), Goldman, Mitchel P. (wikipedia.org)
  • It begins at the lateral aspect of the ankle and runs up the posterolateral lower leg to join the popliteal vein in the popliteal fossa. (medscape.com)
  • A 61-year-old male patient presented with rest pain and ulceration in his left leg 1 week after a hybrid procedure with bilateral external iliac stenting, common femoral artery thromboendarterectomy, and left-sided femoral popliteal bypass with an in situ saphenous vein. (lu.se)
  • This combination avoids multiple vein cannulation in the GSV along the thigh as well as the need for antegrade infusion when GSV cannulation at the lower tibia is prohibited by a large ulcer area. (bvsalud.org)
  • The saphenous nerve runs laterally alongside the saphenous vein, giving off a medial cutaneous nerve that supplies the skin of the anterior thigh and anteromedial leg. (medscape.com)
  • Aneurysmal dilation of a saphenous vein aortocoronary graft remains a rare complication. (elsevierpure.com)
  • Anatomic course of great saphenous vein. (medscape.com)
  • The great saphenous vein is a large venous blood vessel running near the inside surface of the leg from the ankle to the groin. (healthline.com)
  • Saphenous Corporate Created by simply Nearly Totally Duplicated Great Saphenous Spider vein. (hdac-inhibitors.com)
  • The freshwater stingray, due to its sharp characteristics, injured the great saphenous vein, requiring surgical intervention. (bvsalud.org)
  • In-stent restenosis and atherosclerosis in a human saphenous vein graft. (ox.ac.uk)
  • Association of Angiotensin-Converting Enzyme Genotype, Insertion/Deletion Polymorphism and Saphenous Vein Graft Atherosclerosis in Iranian Patients. (cdc.gov)
  • Regional block of the saphenous nerve, a pure sensory nerve of the leg, allows for rapid anesthetization of the anteromedial lower extremity, including the medial malleolus. (medscape.com)
  • [ 1 ] Because of the lower number of injections, saphenous nerve block is better tolerated by the patient and limits the chance of a needlestick injury to the provider. (medscape.com)
  • The saphenous nerve block is gaining popularity not only for procedural anesthesia but also for treatment of pain after procedures. (medscape.com)
  • Understanding the anatomical distribution of the saphenous nerve helps when performing a successful saphenous nerve block. (medscape.com)
  • The saphenous nerve is a cutaneous branch of the femoral nerve originating from the L2-L4 nerve roots. (medscape.com)
  • Descent of the saphenous nerve down the anteromedial aspect of the leg. (medscape.com)
  • The saphenous nerve travels to the dorsum of the foot, medial malleolus, and the area of the head of the first metatarsal. (medscape.com)
  • At the level of ankle, the saphenous nerve is found between the medial malleolus and the anterior tibial tendon, just lateral to the saphenous vein. (medscape.com)
  • Saphenous nerve dermatome of the anteromedial leg. (medscape.com)
  • Saphenous nerve dermatome at the level of the foot. (medscape.com)
  • As part of an ankle block required to manipulate a fractured or dislocated ankle (A combination of posterior tibial , saphenous, superficial peroneal , deep peroneal, and sural nerve blocks results in complete block of sensory perception beneath the ankle. (medscape.com)
  • The areas to anesthetize include a line along the anterior ankle for the superficial peroneal nerve (blue line), the deep peroneal nerve (red star), the saphenous nerve (pink star), the sural nerve (green arrow), and the posterior tibial nerve (orange arrow). (medscape.com)
  • Key associated structures are the saphenous nerve, femoral cutaneous nerve, and saphenous branch of the genicular artery. (medscape.com)
  • Among patients with a saphenous vein graft lesion undergoing PCI, DES were not superior to BMS at preventing target vessel failure. (acc.org)
  • The fundamental difference is that it preserves the saphenous vein, unlike the vast majority of techniques offered to patients today, which are based on destroying the saphenous vein. (veine-institut.paris)
  • Reijnen and colleagues treated 104 greater saphenous veins in 85 patients at two participating centres. (vascularnews.com)
  • Methods and Results: We identified all patients who underwent saphenous vein graft stenting during the SOS Trial enrollment period (May 2005 and October 2007) at our institution. (elsevierpure.com)
  • Of the 97 patients who underwent saphenous vein graft stenting during the study period, 62 patients (64%) were enrolled in SOS. (elsevierpure.com)
  • Cole I, Glass C, Norton HJ, Tayal V. Ultrasound measurements of the saphenous vein in the pediatric emergency department population with comparison to i.v. catheter size. (medscape.com)
  • Recovery of intralipid from lumbar puncture after migration of saphenous vein catheter. (bmj.com)
  • Notice that the tip of the catheter is malpositioned and is visible within the azygous vein (arrow). (avma.org)
  • Surgical vein stripping reduces pain and improves the appearance of your leg. (medlineplus.gov)
  • Vein stripping is used to remove or tie off a large vein in the leg called the superficial saphenous vein. (medlineplus.gov)
  • High pressure within the superficial system is transmitted to small subcutaneous veins, which can become dilated and tortuous varicosities. (medscape.com)
  • Incompetence of the perforator and short saphenous veins can result in posterior calf varicosities. (medscape.com)
  • Endoscopic vein harvesting can be used to extract the vein from the leg minimally invasively. (wikipedia.org)
  • It is a superficial vein, being subcutaneous (just under the skin). (wikipedia.org)
  • [ 9 , 10 ] Although the procedure can be performed at multiple sites along the length of the GSV, it is commonly performed at the ankle because the predictable and superficial location of the vein in this area allows it to be exposed with minimal dissection. (medscape.com)
  • Likewise, the SSV vein can be harvested either with an open procedure or endoscopically. (medscape.com)
  • Lateral radiographic view of a dog with a VAP after surgery was completed to implant the VAP in a jugular vein by use of recommended anatomic landmarks. (avma.org)
  • Recently, we have shown that blood flow patterns at vein valves induce oscillatory stress genes, which maintain an anticoagulant endothelial phenotype that inhibits spontaneous clotting at vein valves and sinuses, is lost in the presence of DVT in human pathological samples, and is dependent on expression of the transcription factor FOXC2. (gentaurpub.com)
  • Within the veins, a system of valves helps overcome the pull of gravity and maintains a unidirectional flow of blood (shown) . (medscape.com)
  • Normally, valves in your veins keep your blood flowing up toward the heart, so the blood does not collect in one place. (medlineplus.gov)
  • Vascular tension was determined in rings of human internal mammaria arteries and saphenous veins. (nih.gov)
  • In precontracted arteries and veins, addition of sildenafil (0.1-10 microM) led to pronounced vasorelaxation (maximal 35.5 +/- 2.2% and 45.6 +/- 6.3%, respectively, in the presence of 10 microM sildenafil). (nih.gov)