Salvage therapy for failures. Medical search. Frequent questions

To analyze the patterns of locoregional failure in patients with head-and-neck cancer treated with inverse planning intensity-modulated radiotherapy (IMRT). (nih.gov)
Background: Disease progression following salvage radiotherapy (SRT) for prostate cancer (PC) is common, and the time to biochemical recurrence (BCR) is heterogeneous. (elsevierpure.com)
Patient summary: Many men will develop biochemical recurrence of prostate cancer after salvage radiotherapy. (elsevierpure.com)
Men with biochemical recurrence within 18 mo of salvage radiotherapy constitute a cohort at higher risk of distant metastasis and prostate cancer-specific mortality. (elsevierpure.com)
In reality a salvage radical prostatectomy can be considered for men with locally recurrent prostate cancer after external beam radiotherapy has failed. (malecare.org)
RADIOTHERAPY, ALSO KNOWN as radiation therapy, is a treatment where ionizing x-ray and gamma ray radiation are directed at tumors and used to kill cancer cells. (endalldisease.com)
This study involving patients with biochemical recurrence of prostate cancer following radical prostatectomy found that early initiation of salvage radiotherapy at a PSA level ≤0.5 ng/mL was predictive of better oncologic outcomes. (practiceupdate.com)
To evaluate the impact of postoperative radiotherapy (PORT) on patterns of failure and survivals in uterine carcinosarcoma patients treated with radical surgery. (e-roj.org)
Considering that adjuvant radiotherapy after surgical resection was effective to decrease loco-regional recurrence and most treatment failures were distant metastasis, multimodal therapy including surgery, radiotherapy, and chemotherapy might be an optimal treatment for uterine carcinosarcoma patients. (e-roj.org)
Serial PET imaging distinguished end-of-treatment PET positive patients without treatment failure, thereby reducing unnecessary radiotherapy by 80%, and should be considered in all patients with an initial positive PET following dose-adjusted-EPOCH-R (clinicaltrials.gov identifier 00001337). (stanfordhealthcare.org)
The new findings showed no difference in the rate of 10-year freedom from distant metastases or overall survival in patients who received adjuvant radiotherapy vs those who underwent observation with salvage radiotherapy if their disease progressed and provided further confirmation of earlier results reported in The Lancet in 2020 . (medscape.com)
Observation with early salvage radiotherapy in cases of biochemical failure should be the standard of care, concluded study co-author Noel Clarke, MBBS, who presented the results at the European Society for Medical Oncology (ESMO) Congress 2023 in Madrid on October 20. (medscape.com)
Invited discussant and session co-chair Shahneen Sandhu, MBBS, said that the findings definitively confirm the value of observation with salvage radiotherapy over adjuvant radiotherapy in this patient population. (medscape.com)
The approach of early salvage radiotherapy spared morbidity [from] radiation in the vast majority of patients, and further bowel and bladder toxicity is reduced in the setting of salvage radiotherapy," said Sandhu, an associate professor and consultant medical oncologist at Peter MacCallum Cancer Centre, Victoria, Australia. (medscape.com)
In the study, 697 patients were randomly assigned to adjuvant radiotherapy and 699 to observation with salvage radiotherapy. (medscape.com)
Patients in the observation arm received salvage radiotherapy if they experienced two consecutive PSA increases ≥ 0.1 ng/mL or three consecutive rises. (medscape.com)
However, self-reported urinary and fecal incontinence rates at 1 year were significantly higher in the adjuvant radiotherapy group vs the observation group, 60% of whom had not received salvage radiotherapy at that time. (medscape.com)
Overall, the trial results "support the use of early salvage radiotherapy for PSA failure after radical prostatectomy rather than early adjuvant intervention, " concluded Clarke, a professor and consultant urologist at The Christie Hospital and Salford Royal Hospital, Manchester, United Kingdom. (medscape.com)

We find that many men will experience early biochemical recurrence following postprostatectomy salvage radiation therapy. (elsevierpure.com)
To determine outcomes and toxicity of contemporary salvage radiation therapy (SRT) to the prostate bed. (ima.org.il)
He has personally treated 3200 head and neck patients, and gained leading technical expertise and judgement in the formulation and delivery of radiation therapy. (mdanderson.org)
Over the decades Dr. Morrison has been involved in trials of fractionation, radiation protectors, induction and concurrent chemotherapy, and proton beam therapy. (mdanderson.org)
Outcomes after radiation therapy for T2N0/stage II glottic squamous cell carcinoma. (mdanderson.org)
Salvage Radical Prostatectomy for Recurrent Prostate Cancer after Radiation Therapy. (malecare.org)
I often discuss the use of salvage radiation after surgery has failed and the PSA begins to rise. (malecare.org)
Although often mentioned, but seldom used, men who fail radiation as a primary treatment can also benefit from salvage surgery. (malecare.org)
Conventional radiation therapy has not been effective in controlling this type of tumor in the curative or adjuvant settings. (cancernetwork.com)
On the other hand, the failure of radiation to control RCC in the curative or adjuvant setting may have more to do with the tolerance of neighboring structures to the kidney than intrinsic tumor resistance. (cancernetwork.com)
Whole-brain radiation therapy (WBRT) has been the community standard for treating brain metastases from many types of cancers. (cancernetwork.com)
One hundred eighteen patients (35%) underwent whole-brain radiation therapy (WBRT). (thejns.org)
Current primary recommendations for non-metastatic anal cancer include concurrent chemotherapy and radiation therapy. (medscape.com)
the National Comprehensive Cancer Network (NCCN) lists 5FU plus cisplatin and radiation therapy as a category 2B rcommendation. (medscape.com)
PATIENT SUMMARY: Patients with invasive bladder cancer who cannot tolerate surgery were treated with radiation and systemic therapy without surgically removing their bladders. (bvsalud.org)
PURPOSE: To determine whether addition of external beam radiation therapy (EBRT) to brachytherapy (BT) (COMBO) compared with BT alone would improve 5-year freedom from progression (FFP) in intermediate-risk prostate cancer. (bvsalud.org)
It appears that risk is elevated if people have had antecedent hematologic malignancies, environmental exposures to carcinogens, or had previous chemotherapy, radiation, or immunosuppressant therapy. (pharmacytimes.com)
The optimal timing to initiate salvage radiation therapy after prostatectomy is unclear. (practiceupdate.com)
This study evaluated the outcomes of salvage radiation therapy initiated at a PSA level ≤0.5 ng/mL in patients with biochemically recurrent prostate cancer. (practiceupdate.com)
The study included 397 patients, with 45.8% of the patients receiving treatment when their pre-radiation therapy PSA levels were ≤0.5 ng/mL. (practiceupdate.com)
They found that pre-radiation therapy PSA level was the most significant predictor of biochemical recurrence-free survival and metastasis-free survival outcomes. (practiceupdate.com)
It is also known to frequently occur in postmenopausal women, especially in those who have received pelvic radiation therapy [ 2 , 3 ]. (e-roj.org)
Other options are radiation therapy (RT) and whole-gland or focal repeat ablations, although these have only been described after whole-gland ablation. (endourology.ph)

CONCLUSIONS: In a cohort of patients with muscle-invasive bladder cancer who are not candidates for cystectomy or cisplatin chemotherapy, chemoradiation therapy offers a treatment with a significant response rate and 34% 5-yr overall survival. (bvsalud.org)

Eradication therapy of symptomatic H. pylori infection substantially reduces the recurrence of associated gastroduodenal diseases. (cdc.gov)
Should salvage surgery be considered for local recurrence after definitive chemoradiation in locally advanced non-small cell lung cancer? (biomedcentral.com)
The term "salvage surgery" is traditionally used in the multimodal management of the rectal and anal cancer as a part of "watch and wait" policy and is usually indicated for late local recurrence and/or for incomplete clinical response after neo-adjuvant chemoradiation [ 7 - 9 ]. (biomedcentral.com)
The progression-free survival was defined as the interval between the salvage resection and locoregional or distant recurrence of the tumor. (biomedcentral.com)
There is little 12-month data available for other therapies, but recurrence rates almost always increase with time. (prostatecancer.news)
Although the predominant failures were distant metastasis in PORT group and loco-regional recurrence in non-PORT group, there was no statistically significant difference in loco-regional recurrence-free survival (LRRFS) (p = 0.362) or distant metastasis-free survival (DMFS) (p = 0.548). (e-roj.org)

Seventeen locoregional failures (persistent or recurrent disease) were found. (nih.gov)
Salvage therapy may be needed for recurrent or persistent disease after the use of chemoradiotherapy. (medscape.com)
Salvage lung resection for locally recurrent or persisted NSCLC in selected patients with locally advanced NSCLC following definitive chemoradiation is a worthwhile treatment option. (biomedcentral.com)

In this issue, Zakrajsek and colleagues report the findings of a retrospective, observational cohort study designed to determine if treatment with ECMO is associated with lower mortality in refractory asthma exacerbations with respiratory failure. (chestnet.org)
These results suggest ECMO may be an important salvage therapy for individuals with refractory asthma exacerbations with respiratory failure. (chestnet.org)
Chimeric antigen receptor T (CART) cell therapy targeting the B cell specific differentiation antigen CD19 has shown clinical efficacy in a subset of relapsed/refractory (r/r) diffuse large B cell lymphoma (DLBCL) patients. (frontiersin.org)
Research Objective These studies will produce a new CAR-targeted iPSC-derived macrophage-based cell therapy product for treatment of refractory malignancies such as ovarian cancer. (ca.gov)
To evaluate colectomy-free survival in patients with ASUC refractory to intravenous steroids who had failed infliximab (IFX) or ciclosporin (CyA) and received a second salvage therapy. (ecco-ibd.eu)
Multicentre study of patients admitted with ASUC refractory to corticosteroids who failed CyA or IFX and had received a second salvage therapy during the same hospital stay. (ecco-ibd.eu)

We report on our series of patients who underwent salvage lung resections for local NSCLC relapse or tumor persistence following the definitive CRT. (biomedcentral.com)
The medical records of 9 consecutive patients, who underwent salvage lung resections at single institution between March 2011 and November 2013, were reviewed. (biomedcentral.com)
The retrospective descriptive study was analyzed among ISSNHL patients who underwent ITD injection after the failure of oral prednisolone therapy. (tci-thaijo.org)

Sofosbuvir is a common component of current de novo or salvage combination therapies, that targets the HCV NS5B polymerase. (jenner.ac.uk)
Comparison of First-Line Anti-PD-1-Based Combination Therapies in Metastatic Renal-Cell Carcinoma: Real-World Experiences from a Retrospective, Multi-Institutional Cohort. (endourology.ph)

The predominant tumor failure within CTV1 may imply the need to identify patients with radioresistant tumor subvolumes (such as hypoxic regions) within the CTV. (nih.gov)
Posaconazole can be used off-label for salvage treatment in patients intolerant to amphotericin B. It has also been used as step-down therapy after initial control of the disease with amphotericin. (medscape.com)
Abstract Background: Metastasectomy for selected patients with melanoma was associated with improved survival in the era before effective systemic therapy. (melanoma.org.au)
It is unclear if inhaled corticosteroid (ICS) therapy can reduce all-cause mortality in patients or subgroups of patients with COPD. (chestnet.org)
They found that ICSs, particularly when included as triple therapy, were associated with a reduction in all-cause mortality among patients with COPD (OR 0.73). (chestnet.org)
Blood cell and serum markers, along with clinical data of DLBCL patients who were scheduled for CART cell therapy were evaluated to search for biomarkers predicting CART cell responsiveness. (frontiersin.org)
Patients received medical services at a non-urban, Ryan White funded clinic and were on 'salvage' therapy (defined as ≥ 3 agents from at least 3 classes) between July 2016 and July 2021. (aahivm.org)
3 patients in the simplified group and 5 in the non-simplified group experienced virologic failure, however no emergence of new resistance mutations was observed. (aahivm.org)
Impact The proposed off-the-shelf HSC-engineered iNKT therapy has the potential to become a general cancer immunotherapy for treating multiple cancers and a large population of cancer patients. (ca.gov)
Assessment and management of heart failure in patients with chronic kidney disease. (qxmd.com)
Beta-blocker therapy in patients with acute myocardial infarction: not all patients need it. (qxmd.com)
26 of these patients had salvage therapy consisting of abdominoperineal resection, and of these patients, 43% had long-term 5-y survival and control of their disease. (medscape.com)
Patients with lymphovascular disease will have treatment failure early, and 40% will develop disease in the retroperitoneal area and elsewhere. (ascopost.com)
Patients who [have disease progression on surveillance] and go on to get salvage therapy with three to four cycles of BEP require postchemotherapy surgery more commonly. (ascopost.com)
Experience with salvage lung resections in patients with locally relapsed NSCLC after definitive chemoradiation is limited. (biomedcentral.com)
A local tumor relapse rate of up to 35 % can be expected in patients after definitive CRT and remains the dominant cause of death after the initial therapy [ 3 ]. (biomedcentral.com)
To study factors affecting hearing improvement in ISSNHL patients with ITD as a salvage treatment after failure of oral prednisolone therapy. (tci-thaijo.org)
The aim of this study was to explore a role of EMDA®-MMC as first line salvage treatment in patients suffering from HGNMIBC unresponsive to BCG. (auanet.org)
The EMDA®-MMC is a safe and effective tool in the long term conservative treatment of the high-risk NMIBC unresponsive to BCG, as second line "sparing bladder" therapy in selected patients. (auanet.org)
Seven out of 19 (36.8%) patients showed treatment failures, which all happened within 12 months. (e-roj.org)
With the development of direct-acting antivirals, treatment of chronically infected patients has become highly effective, although a subset of patients responds less well to therapy. (jenner.ac.uk)
Six patients remain alive without relapse after salvage endoscopic therapy. (elsevierpure.com)
Even with the approval of new drug therapies, he expects that still better treatment options will come rapidly through ongoing trials and most importantly, that all patients with Hepatitis C are curable. (peterruanemd.com)
Four retrospective series assessed salvage treatments after FT failure evaluating cases of radical prostatectomy (RP) and repeat ablation (sample size from 12 to 22 patients). (endourology.ph)
End-of-treatment PET, however, does not accurately identify patients at risk of treatment failure, thereby confounding clinical decision making. (stanfordhealthcare.org)
Among patients with a positive end-of-treatment PET, only 5/25 (20%) had treatment-failure. (stanfordhealthcare.org)
Colistin is an old antibiotic that has been reintroduced as salvage therapy in hospitalised patients because it is frequently the only agent active against Gram-negative bacteria. (bvsalud.org)
The study identified multiple stewardship opportunities to optimise colistin therapy in hospitalised patients. (bvsalud.org)

Secondary outcome measures, including biochemical progression-free survival and time to further hormone therapy, were also similar in the treatment and observation arms. (medscape.com)

This study aimed to evaluate the outcomes of salvage metastasectomy after failure of systemic therapy. (melanoma.org.au)

8. Norris CH. Drugs affecting the inner ear: a review of their clinical efficacy, mechanisms of action, toxicity, and place in therapy. (tci-thaijo.org)
We see that compared to whole-gland SBRT, it is less curative, Severe (requiring intervention) acute urinary toxicity is higher with TULSA-PRO, although late-term Grade 2 urinary toxicity is lower (not severe for either therapy). (prostatecancer.news)
Rectal toxicity is not an issue for either therapy. (prostatecancer.news)
Various guidelines for colistin administration have led to confusion in establishing the appropriate dose, which has potential for adverse consequences including treatment failure or toxicity. (bvsalud.org)

Stage I-III (locoregional disease) - Available modalities are endoscopic therapies (eg, mucosal resection or ablation), esophagectomy, preoperative chemoradiation, and definitive chemoradiation. (medscape.com)

endoscopic therapy (n = 7) or surgery (n = 2). (elsevierpure.com)

disorder that results in the inability to salvage adenine for purine synthesis. (msdmanuals.com)
This enzyme is produced in all cells and is part of the purine salvage pathway, which recycles a group of DNA building blocks (nucleotides) called purines to make other molecules. (medlineplus.gov)

Median interval between chemoradiation and salvage resection was 30.2 weeks. (biomedcentral.com)

Subsequently they were treated with salvage surgery for clinically localized prostate cancer once their PSA scores again began to rise. (malecare.org)

Anal cancer treatment protocols are provided below, including those for limited localized disease, metastatic disease, salvage therapy, and additional special considerations. (medscape.com)
Regorafenib and TFTD+B are both standard salvage options for metastatic CRC. (mybestmedicine.com)

Starting with our Asthma content area, controlled studies showing the outcomes of extracorporeal membrane oxygenation (ECMO) as salvage therapy for asthma exacerbations with respiratory failure have not been performed. (chestnet.org)

There was an improvement in PSA failure, metastasis rates and prostate cancer-related deaths. (fcshemoncreview.com)
Secondary end points included prostate cancer-specific mortality (PCSM), non-PCSM, distant metastases (DMs), PSA failure, and rates of salvage therapy. (fcshemoncreview.com)
Improvements in metastases rates, prostate cancer deaths, and PSA failures should be weighed against the risk of adverse events and the impact of STAD on quality of life. (fcshemoncreview.com)
Salvage Local Treatments After Focal Therapy for Prostate Cancer. (endourology.ph)
Whether focal therapy (FT) for prostate cancer (PC) jeopardizes outcomes from salvage treatments is a matter of debate still to be resolved. (endourology.ph)
We performed a literature search to determine the treatment options available for prostate cancer after failure of focal therapy and their outcomes. (endourology.ph)

Among 6 treatment failures, the median end-of-treatment SUVmax was 15.4 (range, 1.9-21.3), and 4 achieved long-term remission with salvage therapy. (stanfordhealthcare.org)

Purines may be synthesized de novo or recycled by a salvage pathway from normal catabolism. (msdmanuals.com)

The primary end point was FFP: PSA failure (American Society for Therapeutic Radiology and Oncology [ASTRO] or Phoenix definitions), local failure, distant failure, or death. (bvsalud.org)
However, unlike the uterine leiomyosarcomas, the uterine carcinosarcomas exhibit more isolated local recurrences or lymph node metastasis rather than distant failure, which is similar to the failure pattern in uterine carcinomas [ 4 ]. (e-roj.org)
The failure patterns were (overlap included): local failure (n = 12), nodal metastasis (n = 12), distant metastasis (n = 3), details unknown (n = 2). (elsevierpure.com)

Emerging evidence shows that these benefits persist even in this era of BRAF-targeted therapy and immune checkpoint inhibitor immunotherapy. (melanoma.org.au)
Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? (bmj.com)

If the patient responds completely and goes into remission, he or she progresses to consolidation with postremission therapy or transplant. (pharmacytimes.com)
In both cases-incomplete response or complete remission—if the disease eventually relapses, clinicians will move to salvage therapy. (pharmacytimes.com)
The goals of therapy for AML include complete remission, restoration of normal hematopoietic functions, and no evidence of measurable residual disease. (pharmacytimes.com)

The most common causes of treatment failure are patient noncompliance and antimicrobial resistance of the infecting H. pylori strain ( 5 ). (cdc.gov)
Impact In some liver-based metabolic diseases, replacement of 5-10% of the liver mass may salvage the patient. (ca.gov)
the choice depends on patient performance status and degree of local failure. (medscape.com)
Due to the limited experience, the patient selection criteria for salvage resections remain unclear. (biomedcentral.com)
Association of Gleason Grade With Androgen Deprivation Therapy Duration and Survival Outcomes: A Systematic Review and Patient-Level Meta-analysis. (ohsu.edu)

H. pylori infection is curable with regimens of multiple antimicrobial agents, and antimicrobial resistance is a leading cause of treatment failure. (cdc.gov)
This observational, retrospective cohort study described virologic outcomes of a single-center initiative evaluating ART simplification among PWH with a history of multi-drug resistance and treatment failure. (aahivm.org)
This is the price to pay if you have treatment failure and require three cycles of BEP. (ascopost.com)

The study of factors affecting hearing improvement is an important thing to evaluate the prognosis after therapy. (tci-thaijo.org)
Based on the present study, the adverse hearing recovery prognosis factors for ITD as salvage therapy after the failure of oral prednisolone in ISSNHL are advanced age, diabetes, smoking, the severity of ISSNHL and delayed first ITD after six weeks from the onset of symptoms. (tci-thaijo.org)

We present our series of salvage lung resections for local NSCLC relapse after curative-intent chemoradiation for locally advanced tumor. (biomedcentral.com)

Owing to decreased risk of nephrotoxicity at this dose, it can be used in the setting of preexisting renal dysfunction and when nephrotoxicity develops during amphotericin B deoxycholate therapy. (medscape.com)
Based on its pathophysiology and the resemblance of CRS to sepsis and septic shock, as well as based on the principles of initiation of continuous renal replacement therapy (CRRT) in sepsis, we propose the rationale of using CRRT therapy as an adjunct treatment in CRS where all the other approaches have failed in controlling the clinically significant manifestations. (bmj.com)
Management of chronic renal failure. (docksci.com)
Accumulated adenine is oxidized to 2,8-dihyroxyadenine, which precipitates in the urinary tract, causing problems similar to those of uric acid nephropathy (eg, renal colic, frequent infections, and, if diagnosed late, renal failure). (msdmanuals.com)
As a result, kidney function can decline, which may lead to end-stage renal disease (ESRD), a life-threatening failure of kidney function. (medlineplus.gov)

Failure of rapid agglutination methods to detect oxacillin-resistant Staphylococci aureus also resistant to trimethoprim-sulfamethoxazole and rifampin. (peterruanemd.com)

We also discuss intratumoral genetic heterogeneity as one explanation for therapeutic failures and explain how ultra-long extensions of glioma cells, called tumor microtubes, mediate therapeutic resistance. (medscape.com)

Severe acute hepatic crisis that can progress to multi-organ failure. (pedemmorsels.com)

Current statistics report an increase in the incidence of hematological and oncological malignancies, 1 but treatment with immune-based therapies have also risen in both use and efficacy. (bmj.com)

And then certainly critical illness and you'll hear about that by our presenters, which include respiratory failure, or ARDS, septic shock, multi-organ dysfunction and failure. (cdc.gov)

of heart Failure Treatment study. (qxmd.com)
with heart failure, including non-diabetics. (qxmd.com)
Does thrombolytic therapy salvage lives disabled by angina or heart failure? (docksci.com)

Research Objective The expected outcome is a therapeutic candidate, allogeneic HSC-engineered HLA-I/II-negative human iNKT cells, that can potentially be used as an off-the-shelf cellular therapy for treating cancer. (ca.gov)

In this issue, Chen and colleagues report the results of a systematic review and meta-analysis to determine if inhaled therapy containing ICSs reduces all-cause mortality. (chestnet.org)
The results suggest that regorafenib is a sound option after TFTD+B failure. (mybestmedicine.com)
the results are in line with previous reports for salvage regorafenib. (mybestmedicine.com)
10. Dispenza F, De Stefano A, Costantino C, Marchese D, Riggio F. Sudden sensorineural hearing loss: results of intratympanic steroids as salvage treatment. (tci-thaijo.org)
While it seems that FT has a minimal impact on salvage treatment results, prospective controlled studies are needed to confirm these preliminary data. (endourology.ph)
HPRT deficiency results in failure of the salvage pathway for hypoxanthine and guanine. (msdmanuals.com)

FLT3 inhibitors have emerged as a frontline therapy in AML. (pharmacytimes.com)

4. Dispenza F, Amodio E, De Stefano A, Gallina S, Marchese D, Mathur N, Riggio F. Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy: a randomized clinical study. (tci-thaijo.org)
12. Eftekharian A, Amizadeh M. Pulse steroid therapy in idiopathic sudden sensorineural hearing loss: a randomized controlled clinical trial. (tci-thaijo.org)
During his 25 years of diagnosing and battling complex infections related to HIV and then mastering antiviral therapy as it became available, he developed a strong clinical trial research site helping evolve entirely new therapies for the major RNA virus diseases, first HIV and now Hepatitis C. (peterruanemd.com)

Cell therapies produced from the UDC line will not be rejected by a patient's immune system. (ca.gov)
Research Objective Development of hESC-derived pancreatic beta cells that are protected from allogeneic and autoimmune attack into a cell therapy for type 1 diabetes (T1D) Impact Cell therapy of T1D is challenged by immune rejection. (ca.gov)

Novel predictive biomarkers are needed to identify men harboring micrometastatic disease to avoid potentially futile local therapies or allow for intensification of systemic therapies. (elsevierpure.com)
If extravasation occurs, terminate the infusion at that site and apply local therapy. (pdr.net)
We performed a nonsystematic search of PubMed for articles assessing relevant outcomes for salvage local treatment after FT failure using a manual search. (endourology.ph)

Targeted therapies have become the order of the day combined with conventional therapies for AML. (pharmacytimes.com)

He was one of the first doctors to recommend use of multiple drug therapy in salvage therapy, and is a principle investigator for many of the currently available treatments as well as for new drugs in development. (ukcab.net)

STAD was 6 months of luteinizing hormone-releasing hormone agonist/antagonist therapy plus antiandrogen. (fcshemoncreview.com)

The rationale for esophagectomy as the optimal therapy for Barrett's esophagus with high-grade dysplasia. (medscape.com)

It is driven by the male hormone testosterone, and measures used to block testosterone commonly known as hormonal therapy (Androgen Deprivation Therapy-ADT) forms an important treatment in localised and advanced disease. (mdpi.com)
SIR,-As your Aug 10 editorial hints, there is a pressing need for ways of assessing success or failure in the management of incurable or chronic disease. (docksci.com)

Anatomy5

Organisms1

Diseases36

Chemicals and Drugs51

Analytical, Diagnostic and Therapeutic Techniques and Equipment51

Phenomena and Processes8

Information Science1

Health Care17

Radiotherapy18

Radiation23

Chemotherapy1

Recurrence6

Recurrent3

Refractory6

Underwent3

Combination therapies2

Patients28

Biochemical1

Outcomes of salvage1

Toxicity4

Locoregional1

Endoscopic1

Purine2

Resection1

Surgery1

Metastatic2

Showing the outcomes1

Prostate cancer6

Median1

Novo1

Distant3

Immunotherapy2

Remission3

Patient5

Treatment Failure3

Prognosis2

Relapse1

Renal5

Methods1

Tumor1

Acute1

Efficacy1

Respiratory failure1

Heart Failure3

Therapeutic1

Results6

Inhibitors1

Clinical3

Immune2

Local3

Conventional1

Treatments1

Luteinizing hormone1

Esophagectomy1

Disease2