AnatomyOrganismsDiseasesChemicals and Drugs
SalicylatesSodium SalicylateSalicylic AcidGentisatesAspirinAnti-Inflammatory Agents, Non-SteroidalHydroxybenzoatesBenzoic AcidCatecholsMixed Function OxygenasesTinnitusPseudomonasReye SyndromeChorismic AcidCyclooxygenase InhibitorsCatechol 1,2-DioxygenaseGaultheriaDioxygenasesPhenylbutazoneHair Cells, Auditory, OuterBenzoatesNaphthalenesPhenacetinBenzyl Alcohols
AspirinSodium salicylateSalicylic acidWintergreenMagnesium SalicylateToxicityProduce methyl salicylateMethyl salicylate overdoseSensitivitySerumPhenyl salicylateIncrease salicylateContain salicylatesSymptomsCompoundsEsterIngestionExcretionAnalgesicBenzylSearchReye'sAcuteToxicTinnitusInducesMetabolicLinimentsChronicAmountsDrugsSalicylismConcentrationsAnti-inflammatoryLotionsTissuesPediatricTopicalHttpsMedicinalExposureDefinitionsOccurMedicinesMolecularChemicalsProductsAbstractScientificDosesInsectsTeaspoon
Aspirin10
  • One of Max Samter's earliest theories as to why patients continued to have AERD with nasal polyps, even though they were avoiding aspirin, was that they were each day ingesting either natural food salicylates or yellow dye #5. (aaaai.org)
  • 98% salicylate), and Pepto-Bismol (236 mg of non-aspirin salicylate per 15 mL). (medscape.com)
  • Although concentrations of salicylate persist following ingestion of aspirin tablets, it has been shown that the majority of salicylate concentrations declined following ingestion of salicylate as acetylsalicylic powder. (medscape.com)
  • You should not use this medicine if you are allergic to aspirin or other salicylates. (everydayhealth.com)
  • Also ask a doctor or pharmacist before using any other medicine that may contain diphenhydramine or ingredients similar to magnesium salicylate (such as aspirin or other salicylates). (everydayhealth.com)
  • Salicylates are also found in aspirin and other pain medication. (healthline.com)
  • Reviewed by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Accidental overdose from aspirin is very uncommon in the paediatric population, but methyl salicylate overdose is associated with significant toxicity even with very small ingestions. (innovation-arg.com)
  • Herres J, Ryan D, Salzman M. Delayed salicylate toxicity with undetectable initial levels after large-dose aspirin ingestion. (medscape.com)
  • You are allergic to salicylates (including aspirin) or any other pain reliever/fever reducer. (healthinhand.org)
  • The association of Reye syndrome with salicylates, particularly aspirin, was demonstrated in several epidemiologic studies around the world. (medscape.com)
Sodium salicylate5
  • In addition, such patients, as you know, can tolerate salicylate in the form of sodium salicylate without difficulty (1). (aaaai.org)
  • Add 6.5 ounces (192 mL) of Sodium Salicylate 60% Concentrate with Caffeine 5.7% to make 1 gallon of stock solution and administer through a medicator metered at 1:128 (1 ounce per gallon). (drugs.com)
  • Add 6.5 ounces (192 mL) of Sodium Salicylate 60% Concentrate with Caffeine 5.7% to 128 gallons of drinking water. (drugs.com)
  • The formation, growth, and stability of worm-like micelles formed by cetyltrimethylammonium bromide (CTAB) and sodium salicylate(NaSal) were investigated using the self-fluorescence of salicylate ions and the ability of the giant micelles to promote hydrodynamic drag reduction under turbulent flow. (bath.ac.uk)
  • Bottle for sodium salicylate tablets. (tol.ca)
Salicylic acid2
  • Ingestion of topical products containing salicylates (eg, Ben-Gay, salicylic acid [keratolytic], oil of wintergreen or methyl salicylate), can cause severe salicylate toxicity. (medscape.com)
  • Methyl salicylate can be produced by esterifiying salicylic acid with methanol . (wikidoc.org)
Wintergreen4
  • Methyl salicylate (oil of wintergreen) is a chemical that smells like wintergreen. (medlineplus.gov)
  • Methyl salicylate (C8H8O3, MW 152.15) occurs as a colorless, yellowish, or reddish liquid with the characteristic odor and taste of wintergreen. (contemplation.biz)
  • Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. (contemplation.biz)
  • Ingestion of 5 mL of oil of wintergreen ( methyl salicylate , a component of some liniments and solutions used in hot vaporizers) can kill a young child. (msdmanuals.com)
Magnesium Salicylate16
  • Magnesium salicylate is a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates). (everydayhealth.com)
  • Diphenhydramine and magnesium salicylate is a combination medicine that is used to treat back pain that keeps you awake during your normal sleeping hours. (everydayhealth.com)
  • Diphenhydramine and magnesium salicylate may also be used for purposes not listed in this medication guide. (everydayhealth.com)
  • What is Doans PM (Diphenhydramine Magnesium Salicylate) used for? (everydayhealth.com)
  • Magnesium salicylate may cause stomach or intestinal bleeding, which can be fatal. (everydayhealth.com)
  • These conditions can occur without warning while you are using magnesium salicylate, especially in older adults. (everydayhealth.com)
  • Can I take Doans PM (Diphenhydramine Magnesium Salicylate) if I'm pregnant or breastfeeding? (everydayhealth.com)
  • Use Doans PM (Diphenhydramine Magnesium Salicylate) exactly as directed on the label, or as prescribed by your doctor. (everydayhealth.com)
  • Magnesium salicylate is an internal analgesic available in over-the-counter (OTC) medicines that temporarily relieves minor aches and pains. (healthinhand.org)
  • Magnesium salicylate is part of a group of pain relievers and fever reducers called non-steroidal anti-inflammatory drugs (NSAIDs). (healthinhand.org)
  • The U.S. Food and Drug Administration (FDA) recommends adults take no more than 4,640 milligrams (mg) of magnesium salicylate in a 24-hour period. (healthinhand.org)
  • Different types of products containing magnesium salicylate have different strengths. (healthinhand.org)
  • Magnesium salicylate is approved by FDA and is safe and effective when used according to the Drug Facts label. (healthinhand.org)
  • Do not give an OTC medicine containing magnesium salicylate to children under the age of 12 unless advised by a healthcare provider. (healthinhand.org)
  • Your child or teenager has or is recovering from the chicken pox or flu due to a rare illness (Reye's syndrome) reported to be associated with magnesium salicylate. (healthinhand.org)
  • Magnesium salicylate, like other NSAIDs, may cause a severe allergic reaction. (healthinhand.org)
Toxicity11
  • Salicylate toxicity has been reported with the topical use of salicylate-containing teething gels in infants. (medscape.com)
  • In a study of 599 cases of salicylate exposure in children less than 6 years old, the majority of children with signs of salicylate toxicity (metabolic acidosis, tachypnea) were exposed to liquid preparations. (medscape.com)
  • The acid-base, fluid, and electrolyte abnormalities seen with salicylate toxicity can be grouped into phases. (medscape.com)
  • Aside from its toxicity, methyl salicylate may be used by plants as a pheromone to warn other plants of pathogens such as tobacco mosaic virus . (wikidoc.org)
  • Definition: Salicylate toxicity is characterized by a constellation of symptoms caused by acute or chronic overdose of salicylate containing compounds. (innovation-arg.com)
  • Hyperpnea is an early finding of toxicity, as salicylates can act directly on the medullary respiratory center leading to hyperventilation leading to a respiratory alkalosis. (innovation-arg.com)
  • Methyl salicylate is easily characterized by a high degree of toxicity. (innovation-arg.com)
  • Lewis TV, Badillo R, Schaeffer S, Hagemann TM, McGoodwin L. Salicylate toxicity associated with administration of Percy medicine in an infant. (medscape.com)
  • Salicylate toxicity model of tinnitus. (medscape.com)
  • 150 mg/kg of salicylate can cause severe toxicity. (msdmanuals.com)
  • Dehydration, hyperthermia, and chronic ingestion increase salicylate toxicity because they result in greater distribution of salicylate to tissues. (msdmanuals.com)
Produce methyl salicylate2
  • [2] Numerous plants produce methyl salicylate in very small amounts. (wikidoc.org)
  • 204-317-7 For the full text of the H-Statements and R-Phrases mentioned … Wintergreenplants which are botanically referred to as gaultheria procumbens are the oneswhich produce methyl salicylate in significant amounts and they can always berecognized by a rather characteristic scent. (innovation-arg.com)
Methyl salicylate overdose2
  • Methyl salicylate overdose occurs when someone swallows a dangerous amount of a product containing this substance. (medlineplus.gov)
  • Below are symptoms of a methyl salicylate overdose in different parts of the body. (medlineplus.gov)
Sensitivity4
  • Any advice regarding association of salicylates in food and sensitivity decreasing after long term ASA desensitization? (aaaai.org)
  • Before taking physostigmine salicylate tell your doctor if you have sulfite sensitivity . (rxlist.com)
  • The other thing it could also be is a salicylate sensitivity! (noallergiesplease.com)
  • A Salicylate sensitivity is the body's inability to handle more than a certain amount of salicylates at any one time. (noallergiesplease.com)
Serum2
  • Medicinal products Methyl salicylate has anti-inflammatory properties and is still used, A study in 4 human volunteers (Wolowich, 2003) gave a mean time to maximum serum concentration of salicylate of 2.4 hours, confirming the slower absorption in humans reported by Davison … The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. (innovation-arg.com)
  • Diagnosis is clinical, supplemented by measurement of the anion gap, arterial blood gases, and serum salicylate levels. (msdmanuals.com)
Phenyl salicylate1
  • Help support Wordnik (and make this page ad-free) by adopting the word phenyl salicylate . (wordnik.com)
Increase salicylate1
  • Does urine alkalinization increase salicylate elimination? (medscape.com)
Contain salicylates1
Symptoms2
  • However, there is a lack of research on the effects of salicylate elimination on ADHD symptoms and it is not currently recommended as a treatment method for ADHA. (healthline.com)
  • Haslinger V, Dietz W, Bartsch M, Simma B. Salicylate intoxication with symptoms of septicaemia in a 17-month-old girl. (medscape.com)
Compounds2
  • Salicylates are just one group of the hundreds of compounds in foods that can have varying effects on us, depending on how much we eat and how sensitive we are. (noallergiesplease.com)
  • The glue vapors consisted of methyl- salicylate (119368), o-phenylphenol (90437), and various terpene or terpene derivative compounds. (cdc.gov)
Ester2
  • Plants containing methyl salicylate produce this organic ester (a combination of an organic acid with an alcohol ) most likely as an anti- herbivore defense. (wikidoc.org)
  • Benzyl salicylate is a phenolic ester with a musky floral aroma, as found in jasmine, lilac, and carnation. (earthtokathy.com)
Ingestion2
  • Salicylate is available for ingestion as tablets, capsules, and liquids. (medscape.com)
  • Salicylate ingestion continues to be a common cause of poisoning in children and adolescents. (medscape.com)
Excretion2
  • Kirshenbaum LA, Mathews SC, Sitar DS, Tenenbein M. Does multiple-dose charcoal therapy enhance salicylate excretion? (medscape.com)
  • Excretion of salicylates increases when urine pH increases. (msdmanuals.com)
Analgesic2
  • Salicylates are used as analgesic agents for the treatment of mild to moderate pain. (medscape.com)
  • For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. (contemplation.biz)
Benzyl10
  • Physostigmine Salicylate (physostigmine salicylate injection) Injection is available in 2 mL ampules, each mL containing 1 mg of Physostigmine Salicylate (physostigmine salicylate injection) in a vehicle composed of sodium metabisulfite 0.1%, benzyl alcohol 2.0% as a preservative in Water for Injection. (rxlist.com)
  • Benzyl Salicylate is a oil textured liquid, which occurs from colourless to pale yellow colour. (lookmagazines.com)
  • Benzyl salicylate is a UV light absorber and smells like sweet floral and fainted. (lookmagazines.com)
  • Benzyl salicylate has a density of about 1.17 g/cm³. (lookmagazines.com)
  • Countries like China and Japan are adding up to the market growth of benzyl salicylate. (lookmagazines.com)
  • On the other hand, South America is also a fast-growing market for benzyl salicylate. (lookmagazines.com)
  • Procurement Resource does an in-depth analysis of the price trend to bring forth the monthly, quarterly, half-yearly, and yearly information on the benzyl salicylate price, neopentyl glycol price and tetrabromobisphenol a price etc. in its latest pricing dashboard. (lookmagazines.com)
  • The benzyl salicylate price chart, pricing database, and analysis can prove valuable for the procurement managers, directors, and decision-makers to build up their strongly backed up strategic insights to attain progress and profitability in the business. (lookmagazines.com)
  • Industrial uses impacting the benzyl salicylate price trend primarily include self-care and personal care products, flavouring and fragrance agents, UV absorber in cosmetics, fixation in the floral perfumes, and solvents. (lookmagazines.com)
  • Benzyl salicylate may be sensitizing and is restricted by the International Fragrance Association. (earthtokathy.com)
Search1
Reye's1
  • Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children. (everydayhealth.com)
Acute2
  • Rauschka H, Aboul-Enein F, Bauer J, Nobis H, Lassmann H, Schmidbauer M. Acute cerebral white matter damage in lethal salicylate intoxication. (medscape.com)
  • Ointments or liniments containing methyl salicylate are applied topically as counter irritant for relief of acute pain associated with lumbago,sciatica and rheumatic conditions. (contemplation.biz)
Toxic3
  • According to published sources, one teaspoon of 98% methyl salicylate contains as much as 7000 mg of salicylate, the equivalent of nearly 90 baby aspirins and more than 4 times the potentially toxic dose for a child who weighs 10 kg. (medscape.com)
  • In pure form, methyl salicylate is toxic, especially when taken internally. (wikidoc.org)
  • Toxic ingestions of salicylates typically occur with doses of approximately 150 mg/kg body weight. (innovation-arg.com)
Tinnitus1
  • Previous studies have demonstrated efficacy of nimodipine, an L-type calcium channel blocker, on reversing these changes in salicylate and quinine induced tinnitus in rat models (Jastreboff, 1991). (cdc.gov)
Induces2
  • Volatile methyl salicylate induces systemic signalling in the phylloxerated root system of hybridised Vitis spp. (iobc-wprs.org)
  • The copper (II) complex of salicylate phenanthroline inhibits proliferation and induces apoptosis of hepatocellular carcinoma cells. (bvsalud.org)
Metabolic2
  • Minor metabolism may occur in various tissues but hepatic metabolism constitutes the majority of metabolic processes of absorbed methyl salicylate. (contemplation.biz)
  • Salicylates simultaneously and independently cause primary metabolic acidosis. (msdmanuals.com)
Liniments1
  • certain plastic containers (polystyrene) are unsuitable for liniments or ointments containing methyl salicylate. (contemplation.biz)
Chronic1
Amounts2
  • Methyl salicylate can be poisonous in large amounts. (medlineplus.gov)
  • Bismuth subsalicylate (8.7 mg salicylate/mL) is another potentially unexpected source of large amounts of salicylate. (msdmanuals.com)
Drugs2
  • Physostigmine Salicylate Injection is an antidote used to reverse the effect of drugs that cause anticholinergic syndrome. (rxlist.com)
  • Other drugs may interact with physostigmine salicylate. (rxlist.com)
Salicylism1
  • Abstract We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. (innovation-arg.com)
Concentrations1
  • In one study, salicylate concentrations increased or changed insignificantly in 50% of patients who ingested tablets, but following powder ingestions, concentrations declined in 94% of cases. (medscape.com)
Anti-inflammatory2
  • Morpholine salicylate is a nonsteroidal anti-inflammatory drug. (wikipedia.org)
  • The plasma half-life for salicylate is 2 to 3 hr in low doses and about 12 hr at usual anti-inflammatory doses. (contemplation.biz)
Lotions1
  • Salicylate is also available for topical application, in creams or lotions. (medscape.com)
Tissues2
  • When applied topically, methyl salicylate is thought to penetrate the skin and underlying tissues where it reversibly inhibits cyclooxygenase enzyme and locally and peripherally prevents the production of inflammatory mediators such as prostaglandin and thromboxane A2. (contemplation.biz)
  • After absorption, methyl salicylate is distributed throughout most body tissues and most transcellular fluids, primarily by pH dependent passive processes. (contemplation.biz)
Pediatric2
  • A comprehensive review of the existing medical literature on methyl salicylate poisoning has determined that it is a relatively common source of pediatric exposures. (medscape.com)
  • A simple modified bicarbonate regimen for urine alkalinization in moderate pediatric salicylate poisoning in the emergency department. (medscape.com)
Topical3
  • Salicylates, topical. (medlineplus.gov)
  • Therefore, consider salicylate poisoning when topical herbal medicinal oil is involved. (medscape.com)
  • [6] It has proven fatal to small children in doses as small as 4 mL. [7] A 17 year-old cross-country runner at Notre Dame Academy on Staten Island, died April 3, 2007, after her body absorbed high levels of methyl salicylate through excessive use of topical muscle-pain relief products. (wikidoc.org)
Https1
  • 2017. https://im.unboundmedicine.com/medicine/view/GDT/619007/all/Salicylate. (unboundmedicine.com)
Medicinal2
  • cis-3 Hexenyl Salicylate is green aromatic floral phenolic-medicinal leathery-mossy modern-powdery-florals gives natural-green-support. (perfumersworld.com)
  • The presence of methyl salicylate in this plant confirms the ethno medicinal importance of L. aestuans. (innovation-arg.com)
Exposure1
Definitions1
  • The chemical synthesis methyl salicylate market report offers a primary overview of the chemical synthesis methyl salicylate industry covering different product definitions, classifications, and participants in the industry chain structure. (researchcorridor.com)
Occur1
  • Salicylates are chemicals that occur naturally in many plants - they're a kind of natural pesticide - to protect the plants against insects and diseases. (noallergiesplease.com)
Medicines1
  • Many of these medicines may contain salicylate. (medscape.com)
Molecular1
  • In the present study, we investigated the antitumor effect and associated molecular mechanisms of the copper (II) complex of salicylate phenanthroline [Cu(sal)(phen)] against hepatocellular carcinoma (HCC). (bvsalud.org)
Chemicals2
  • Methyl salicylate is the most poisonous form of the salicylate type of chemicals. (medlineplus.gov)
  • Salicylates are also found in medications, fragrances, industrial chemicals, plastics and some pesticides, and can cause adverse effects when inhaled as well as eaten. (noallergiesplease.com)
Products2
  • Other products may also contain methyl salicylate. (medlineplus.gov)
  • [ 11 ] Percy Medicine is available OTC, and parents should be educated that salicylate-containing products are not routinely recommended for children aged 1 year or younger. (medscape.com)
Abstract1
  • Abstract: Root phylloxeration stimulates the biosynthesis of methyl salicylate in root gall tissue below-ground. (iobc-wprs.org)
Scientific1
  • Scientific literature review of salicylates and salicylaldehyde. (femaflavor.org)
Doses1
  • The half-life of salicylate may be as long as 15 to 30 hr at high therapeutic doses or when there is intoxication. (contemplation.biz)
Insects1
  • [1] If the plant is infested with herbivorous insects, the release of methyl salicylate may function as an aid in the recruitment of beneficial insects to kill the herbivorous insects. (wikidoc.org)
Teaspoon1
  • A single teaspoon (5 ml) of methyl salicylate contains approximately 6 g of salicylate, which is equivalent to almost twenty 300 mg aspirintablets (5 ml × 1.174 g/ml = 5.87 g). (innovation-arg.com)