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  • Trolamine
  • The US Food and Drug Administration has not reviewed any of the over-the-counter products listed in the Daily Med database that contain trolamine salicylate. (wikipedia.org)
  • Also, the producers of trolamine salicylate products have not provided evidence to the FDA in support of claims that this chemical is directly absorbed through the skin into underlying tissue. (wikipedia.org)
  • However, one study reported that trolamine salicylate does penetrate into, and persist within, underlying muscle tissue. (wikipedia.org)
  • The test subjects used either the trolamine salicylate product or a placebo while engaging in an exercise regimen designed to induce muscle soreness. (wikipedia.org)
  • The experimenters observed that those using the trolamine salicylate product exercised longer before reporting the onset of soreness, reported less intense soreness, and reported that their soreness did not last as long as the people who used the placebo. (wikipedia.org)
  • All of the trolamine salicylate-containing products listed in the two cited references are 10% solutions. (wikipedia.org)
  • displaystyle
  • In enzymology, a salicylate 1-monooxygenase (EC 1.14.13.1) is an enzyme that catalyzes the chemical reaction salicylate + NADH + 2 H+ + O2 ⇌ {\displaystyle \rightleftharpoons } catechol + NAD+ + H2O + CO2 The 4 substrates of this enzyme are salicylate, NADH, H+, and O2, whereas its 4 products are catechol, NAD+, H2O, and CO2. (wikipedia.org)
  • excretion
  • Kirshenbaum LA, Mathews SC, Sitar DS, Tenenbein M. Does multiple-dose charcoal therapy enhance salicylate excretion? (medscape.com)
  • Sodium Salicylate is a gastric irritant and sodium bicarbonate is often given with it to reduce this effect (however the bicarbonate also increases rate of excretion and this lowers the concentration of salicylate in the blood). (intekom.com)
  • insects
  • Salicylates are chemicals that occur naturally in many plants - they're a kind of natural pesticide - to protect the plants against insects and diseases. (fedup.com.au)
  • prostaglandins
  • Salicylates, by inhibiting the synthesis of prostaglandins that occur in inflamed tissues, prevent the sensitization of the pain receptors to mechanical stimulation or to chemicals, such as bradykinin, that appear to mediate pain response. (intekom.com)
  • molecule
  • The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. (wikipedia.org)
  • serum
  • It is therefore possible to quantify the serum salicylate level through the signal strength-the amount of reflected light received. (wikipedia.org)
  • stiffness
  • the pain, essentially nocturnal, is spectacularly but transiently relieved by salicylates and is accompanied by often frank stiffness of the spine. (curehunter.com)